Incidental Mutation 'R9680:Zgrf1'
| ID |
728465 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zgrf1
|
| Ensembl Gene |
ENSMUSG00000051278 |
| Gene Name |
zinc finger, GRF-type containing 1 |
| Synonyms |
4930422G04Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.081)
|
| Stock # |
R9680 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
127347138-127411672 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 127409216 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Cysteine
at position 1730
(Y1730C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000044432
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043108]
[ENSMUST00000196141]
[ENSMUST00000196341]
[ENSMUST00000199888]
[ENSMUST00000200490]
|
| AlphaFold |
Q0VGT4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000043108
AA Change: Y1730C
PolyPhen 2
Score 0.383 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000044432
Gene: ENSMUSG00000051278
AA Change: Y1730C
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF2439
|
3 |
81 |
3.7e-23 |
PFAM |
|
low complexity region
|
92 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
628 |
639 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
906 |
N/A |
INTRINSIC |
|
Pfam:zf-GRF
|
1109 |
1153 |
1.5e-17 |
PFAM |
|
low complexity region
|
1316 |
1328 |
N/A |
INTRINSIC |
|
Pfam:AAA_11
|
1501 |
1608 |
1.6e-21 |
PFAM |
|
Pfam:AAA_12
|
1616 |
1802 |
1.3e-51 |
PFAM |
|
coiled coil region
|
1833 |
1861 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000196141
AA Change: Y1730C
PolyPhen 2
Score 0.383 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000143761
Gene: ENSMUSG00000051278
AA Change: Y1730C
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF2439
|
3 |
81 |
3.7e-23 |
PFAM |
|
low complexity region
|
92 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
628 |
639 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
906 |
N/A |
INTRINSIC |
|
Pfam:zf-GRF
|
1109 |
1153 |
1.5e-17 |
PFAM |
|
low complexity region
|
1316 |
1328 |
N/A |
INTRINSIC |
|
Pfam:AAA_11
|
1501 |
1608 |
1.6e-21 |
PFAM |
|
Pfam:AAA_12
|
1616 |
1802 |
1.3e-51 |
PFAM |
|
coiled coil region
|
1833 |
1861 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000196341
|
| SMART Domains |
Protein: ENSMUSP00000143570
Gene: ENSMUSG00000051278
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
12 |
22 |
N/A |
INTRINSIC |
|
Pfam:zf-GRF
|
225 |
269 |
6.7e-15 |
PFAM |
|
low complexity region
|
432 |
444 |
N/A |
INTRINSIC |
|
Pfam:AAA_11
|
491 |
659 |
7.1e-7 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000199888
|
| SMART Domains |
Protein: ENSMUSP00000142693
Gene: ENSMUSG00000051278
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF2439
|
3 |
82 |
3.5e-22 |
PFAM |
|
low complexity region
|
92 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
628 |
639 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000200490
|
| SMART Domains |
Protein: ENSMUSP00000143585
Gene: ENSMUSG00000051278
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF2439
|
3 |
81 |
3.4e-20 |
PFAM |
|
low complexity region
|
92 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
628 |
639 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 73 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam25 |
T |
A |
8: 41,208,239 (GRCm39) |
Y502N |
probably damaging |
Het |
| Adam6a |
T |
A |
12: 113,509,484 (GRCm39) |
L619* |
probably null |
Het |
| Akap9 |
A |
T |
5: 4,011,587 (GRCm39) |
R763S |
probably benign |
Het |
| Akt3 |
G |
A |
1: 176,958,639 (GRCm39) |
P24S |
probably damaging |
Het |
| Ano2 |
A |
T |
6: 125,857,382 (GRCm39) |
|
probably null |
Het |
| B4galnt4 |
G |
A |
7: 140,647,957 (GRCm39) |
R491Q |
possibly damaging |
Het |
| Bahcc1 |
A |
G |
11: 120,163,286 (GRCm39) |
D528G |
possibly damaging |
Het |
| Camk1g |
G |
T |
1: 193,030,483 (GRCm39) |
Q409K |
probably benign |
Het |
| Cdh3 |
T |
A |
8: 107,274,396 (GRCm39) |
N638K |
probably benign |
Het |
| Cgnl1 |
T |
A |
9: 71,562,632 (GRCm39) |
E882D |
possibly damaging |
Het |
| Cplane1 |
A |
G |
15: 8,231,785 (GRCm39) |
N1077S |
possibly damaging |
Het |
| Cpxm2 |
C |
T |
7: 131,661,651 (GRCm39) |
E379K |
probably damaging |
Het |
| Cyp3a16 |
A |
G |
5: 145,389,690 (GRCm39) |
L225P |
probably damaging |
Het |
| Dchs1 |
T |
C |
7: 105,411,625 (GRCm39) |
E1497G |
probably damaging |
Het |
| Denr |
T |
A |
5: 124,065,117 (GRCm39) |
S157T |
possibly damaging |
Het |
| Disp3 |
A |
G |
4: 148,356,101 (GRCm39) |
I253T |
probably damaging |
Het |
| Dlgap2 |
C |
T |
8: 14,896,653 (GRCm39) |
T1043M |
probably damaging |
Het |
| Epb41l5 |
T |
C |
1: 119,535,804 (GRCm39) |
T355A |
probably damaging |
Het |
| Etv6 |
G |
A |
6: 134,013,062 (GRCm39) |
|
probably benign |
Het |
| Fbn1 |
T |
C |
2: 125,310,484 (GRCm39) |
I141V |
probably benign |
Het |
| Fsip2 |
T |
G |
2: 82,819,272 (GRCm39) |
S5002A |
probably benign |
Het |
| Gbf1 |
T |
G |
19: 46,271,837 (GRCm39) |
V1576G |
probably damaging |
Het |
| Gmfg |
T |
A |
7: 28,140,733 (GRCm39) |
|
probably null |
Het |
| Gsdmc4 |
T |
C |
15: 63,774,706 (GRCm39) |
E25G |
possibly damaging |
Het |
| Igkv6-23 |
A |
T |
6: 70,237,884 (GRCm39) |
L12M |
possibly damaging |
Het |
| Kank1 |
G |
A |
19: 25,388,138 (GRCm39) |
V604M |
probably damaging |
Het |
| Kctd1 |
A |
G |
18: 15,140,822 (GRCm39) |
V40A |
probably damaging |
Het |
| Krt222 |
T |
C |
11: 99,127,065 (GRCm39) |
K185R |
possibly damaging |
Het |
| Ldc1 |
A |
G |
4: 130,115,527 (GRCm39) |
V7A |
probably benign |
Het |
| Lipm |
T |
C |
19: 34,089,494 (GRCm39) |
F151L |
probably damaging |
Het |
| Lrrc2 |
A |
T |
9: 110,791,710 (GRCm39) |
N154I |
probably damaging |
Het |
| Map1a |
T |
A |
2: 121,132,865 (GRCm39) |
M1227K |
probably damaging |
Het |
| Med1 |
T |
C |
11: 98,071,114 (GRCm39) |
T78A |
probably damaging |
Het |
| Mrm1 |
A |
G |
11: 84,710,144 (GRCm39) |
S19P |
possibly damaging |
Het |
| Naf1 |
GCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCCGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCCGCCAGCCCCGAACTGGGATGCGGGCGGAAGACCACCACCGCCGCCAGCCCCGAACTCGGATCCCGGCGGAAGACC |
GCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCCGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCCGCCAGCCCCGAACTGGGATGCGGGCGGAAGACCACCACCGCCGCCAGCCCCGAACTCGGATCCCGGCGGAAGACC |
8: 67,313,200 (GRCm39) |
|
probably benign |
Het |
| Nap1l1 |
A |
G |
10: 111,330,657 (GRCm39) |
Y354C |
probably damaging |
Het |
| Npr1 |
A |
G |
3: 90,368,448 (GRCm39) |
V474A |
probably benign |
Het |
| Nyap1 |
A |
T |
5: 137,733,840 (GRCm39) |
S398T |
probably damaging |
Het |
| Obox7 |
C |
T |
7: 14,398,067 (GRCm39) |
Q36* |
probably null |
Het |
| Or5aq6 |
A |
T |
2: 86,923,390 (GRCm39) |
M117K |
possibly damaging |
Het |
| Or6c8 |
A |
T |
10: 128,915,358 (GRCm39) |
I158N |
probably benign |
Het |
| P3h1 |
T |
A |
4: 119,090,428 (GRCm39) |
L92H |
probably benign |
Het |
| Pappa2 |
T |
C |
1: 158,609,818 (GRCm39) |
T1548A |
possibly damaging |
Het |
| Pnisr |
A |
G |
4: 21,873,586 (GRCm39) |
E443G |
probably damaging |
Het |
| Prdm2 |
A |
G |
4: 142,859,079 (GRCm39) |
S1404P |
possibly damaging |
Het |
| Prom1 |
A |
T |
5: 44,190,284 (GRCm39) |
|
probably null |
Het |
| Rbm27 |
A |
T |
18: 42,455,186 (GRCm39) |
Q646H |
probably damaging |
Het |
| Scamp3 |
C |
T |
3: 89,087,561 (GRCm39) |
R134* |
probably null |
Het |
| Scrt2 |
T |
C |
2: 151,924,018 (GRCm39) |
C17R |
probably benign |
Het |
| Setbp1 |
A |
G |
18: 78,902,498 (GRCm39) |
S390P |
probably benign |
Het |
| Shank2 |
A |
T |
7: 143,964,837 (GRCm39) |
D815V |
probably damaging |
Het |
| Sirt7 |
G |
A |
11: 120,511,296 (GRCm39) |
T285M |
|
Het |
| Sis |
T |
G |
3: 72,863,621 (GRCm39) |
S206R |
probably benign |
Het |
| Slc24a4 |
T |
G |
12: 102,193,334 (GRCm39) |
D206E |
possibly damaging |
Het |
| Slc26a4 |
C |
A |
12: 31,585,292 (GRCm39) |
G501C |
probably damaging |
Het |
| Sptb |
T |
C |
12: 76,677,489 (GRCm39) |
N115S |
probably damaging |
Het |
| Srprb |
T |
C |
9: 103,074,807 (GRCm39) |
T112A |
possibly damaging |
Het |
| Tbk1 |
G |
T |
10: 121,389,841 (GRCm39) |
A537E |
probably benign |
Het |
| Tbx19 |
T |
A |
1: 164,970,067 (GRCm39) |
H274L |
probably damaging |
Het |
| Tmem130 |
A |
G |
5: 144,674,233 (GRCm39) |
S394P |
probably damaging |
Het |
| Tmem40 |
A |
G |
6: 115,718,517 (GRCm39) |
S104P |
possibly damaging |
Het |
| Tmprss2 |
T |
A |
16: 97,379,826 (GRCm39) |
Q158L |
probably damaging |
Het |
| Tnip1 |
A |
T |
11: 54,828,876 (GRCm39) |
V97D |
possibly damaging |
Het |
| Tpr |
T |
A |
1: 150,314,887 (GRCm39) |
S1985T |
probably benign |
Het |
| Traf7 |
CA |
CAA |
17: 24,746,737 (GRCm39) |
|
probably benign |
Het |
| Trio |
G |
T |
15: 27,744,158 (GRCm39) |
N2591K |
possibly damaging |
Het |
| Ushbp1 |
A |
T |
8: 71,838,573 (GRCm39) |
C618S |
possibly damaging |
Het |
| Usp34 |
A |
G |
11: 23,317,385 (GRCm39) |
S834G |
possibly damaging |
Het |
| Vmn2r103 |
C |
A |
17: 20,019,525 (GRCm39) |
C536* |
probably null |
Het |
| Vmn2r124 |
T |
A |
17: 18,293,758 (GRCm39) |
V615D |
probably damaging |
Het |
| Zbtb38 |
G |
A |
9: 96,570,397 (GRCm39) |
T229I |
probably benign |
Het |
| Zfhx4 |
T |
A |
3: 5,465,656 (GRCm39) |
V1963E |
probably damaging |
Het |
| Zfp142 |
G |
A |
1: 74,610,933 (GRCm39) |
T954M |
probably benign |
Het |
|
| Other mutations in Zgrf1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01088:Zgrf1
|
APN |
3 |
127,381,790 (GRCm39) |
splice site |
probably benign |
|
|
IGL01153:Zgrf1
|
APN |
3 |
127,396,055 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01330:Zgrf1
|
APN |
3 |
127,377,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01501:Zgrf1
|
APN |
3 |
127,396,211 (GRCm39) |
splice site |
probably null |
|
|
IGL01827:Zgrf1
|
APN |
3 |
127,409,930 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02600:Zgrf1
|
APN |
3 |
127,394,623 (GRCm39) |
splice site |
probably benign |
|
|
IGL03122:Zgrf1
|
APN |
3 |
127,381,782 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL03365:Zgrf1
|
APN |
3 |
127,392,423 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R0015_Zgrf1_014
|
UTSW |
3 |
127,349,046 (GRCm39) |
splice site |
probably benign |
|
|
R1298_Zgrf1_204
|
UTSW |
3 |
127,377,538 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7175_zgrf1_533
|
UTSW |
3 |
127,357,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0015:Zgrf1
|
UTSW |
3 |
127,349,046 (GRCm39) |
splice site |
probably benign |
|
|
R0243:Zgrf1
|
UTSW |
3 |
127,409,095 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0468:Zgrf1
|
UTSW |
3 |
127,355,690 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R0497:Zgrf1
|
UTSW |
3 |
127,378,299 (GRCm39) |
splice site |
probably benign |
|
|
R0505:Zgrf1
|
UTSW |
3 |
127,366,887 (GRCm39) |
missense |
probably benign |
0.30 |
|
R0511:Zgrf1
|
UTSW |
3 |
127,378,309 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0539:Zgrf1
|
UTSW |
3 |
127,408,841 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0617:Zgrf1
|
UTSW |
3 |
127,381,687 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1298:Zgrf1
|
UTSW |
3 |
127,377,538 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1353:Zgrf1
|
UTSW |
3 |
127,405,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1593:Zgrf1
|
UTSW |
3 |
127,354,675 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1846:Zgrf1
|
UTSW |
3 |
127,409,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1912:Zgrf1
|
UTSW |
3 |
127,356,786 (GRCm39) |
missense |
probably benign |
|
|
R2062:Zgrf1
|
UTSW |
3 |
127,406,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2064:Zgrf1
|
UTSW |
3 |
127,406,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2065:Zgrf1
|
UTSW |
3 |
127,406,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2066:Zgrf1
|
UTSW |
3 |
127,406,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2067:Zgrf1
|
UTSW |
3 |
127,406,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2256:Zgrf1
|
UTSW |
3 |
127,355,646 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2321:Zgrf1
|
UTSW |
3 |
127,356,056 (GRCm39) |
nonsense |
probably null |
|
|
R2381:Zgrf1
|
UTSW |
3 |
127,349,863 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2913:Zgrf1
|
UTSW |
3 |
127,392,356 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R3147:Zgrf1
|
UTSW |
3 |
127,377,797 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R3236:Zgrf1
|
UTSW |
3 |
127,407,024 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3237:Zgrf1
|
UTSW |
3 |
127,407,024 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4433:Zgrf1
|
UTSW |
3 |
127,355,727 (GRCm39) |
missense |
probably benign |
|
|
R4441:Zgrf1
|
UTSW |
3 |
127,379,786 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
R4457:Zgrf1
|
UTSW |
3 |
127,389,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4498:Zgrf1
|
UTSW |
3 |
127,379,749 (GRCm39) |
nonsense |
probably null |
|
|
R4598:Zgrf1
|
UTSW |
3 |
127,394,679 (GRCm39) |
missense |
probably benign |
0.14 |
|
R4701:Zgrf1
|
UTSW |
3 |
127,392,353 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4898:Zgrf1
|
UTSW |
3 |
127,396,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4944:Zgrf1
|
UTSW |
3 |
127,355,517 (GRCm39) |
nonsense |
probably null |
|
|
R5256:Zgrf1
|
UTSW |
3 |
127,396,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5294:Zgrf1
|
UTSW |
3 |
127,394,629 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5358:Zgrf1
|
UTSW |
3 |
127,361,352 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5359:Zgrf1
|
UTSW |
3 |
127,394,814 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5447:Zgrf1
|
UTSW |
3 |
127,356,768 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R5569:Zgrf1
|
UTSW |
3 |
127,354,674 (GRCm39) |
missense |
probably benign |
0.33 |
|
R5887:Zgrf1
|
UTSW |
3 |
127,378,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5914:Zgrf1
|
UTSW |
3 |
127,354,672 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5925:Zgrf1
|
UTSW |
3 |
127,366,853 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R5936:Zgrf1
|
UTSW |
3 |
127,355,902 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R6087:Zgrf1
|
UTSW |
3 |
127,409,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6089:Zgrf1
|
UTSW |
3 |
127,389,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6181:Zgrf1
|
UTSW |
3 |
127,381,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6277:Zgrf1
|
UTSW |
3 |
127,392,461 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6441:Zgrf1
|
UTSW |
3 |
127,381,683 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6659:Zgrf1
|
UTSW |
3 |
127,410,155 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6857:Zgrf1
|
UTSW |
3 |
127,375,096 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6932:Zgrf1
|
UTSW |
3 |
127,353,281 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7008:Zgrf1
|
UTSW |
3 |
127,355,421 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7175:Zgrf1
|
UTSW |
3 |
127,357,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7264:Zgrf1
|
UTSW |
3 |
127,357,218 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7272:Zgrf1
|
UTSW |
3 |
127,392,409 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7298:Zgrf1
|
UTSW |
3 |
127,377,299 (GRCm39) |
nonsense |
probably null |
|
|
R7412:Zgrf1
|
UTSW |
3 |
127,356,720 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7836:Zgrf1
|
UTSW |
3 |
127,357,080 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7945:Zgrf1
|
UTSW |
3 |
127,356,409 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7996:Zgrf1
|
UTSW |
3 |
127,389,573 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8165:Zgrf1
|
UTSW |
3 |
127,357,032 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R8198:Zgrf1
|
UTSW |
3 |
127,389,673 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8296:Zgrf1
|
UTSW |
3 |
127,377,644 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8298:Zgrf1
|
UTSW |
3 |
127,408,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8341:Zgrf1
|
UTSW |
3 |
127,354,564 (GRCm39) |
nonsense |
probably null |
|
|
R8445:Zgrf1
|
UTSW |
3 |
127,379,854 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9088:Zgrf1
|
UTSW |
3 |
127,377,326 (GRCm39) |
missense |
probably benign |
0.21 |
|
R9236:Zgrf1
|
UTSW |
3 |
127,378,312 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9250:Zgrf1
|
UTSW |
3 |
127,379,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9253:Zgrf1
|
UTSW |
3 |
127,392,428 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9464:Zgrf1
|
UTSW |
3 |
127,377,741 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9647:Zgrf1
|
UTSW |
3 |
127,355,251 (GRCm39) |
missense |
probably benign |
0.02 |
|
RF015:Zgrf1
|
UTSW |
3 |
127,356,882 (GRCm39) |
missense |
probably benign |
0.02 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCCATGGCCTTTCTGGGAAG -3'
(R):5'- AACAGTCTCAATCCATCTGTCC -3'
Sequencing Primer
(F):5'- CCTTTCTGGGAAGATAATTTTGGATC -3'
(R):5'- TTTTTCCCAACAGCTGTATACTG -3'
|
| Posted On |
2022-10-06 |
Incidental Mutation