Incidental Mutation 'R9680:Prdm2'
| ID |
728469 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Prdm2
|
| Ensembl Gene |
ENSMUSG00000057637 |
| Gene Name |
PR domain containing 2, with ZNF domain |
| Synonyms |
KMT8, LOC381568, Riz, E330024L24Rik, 4833427P12Rik, Riz1 |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9680 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
142833961-142939560 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 142859079 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 1404
(S1404P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000101404
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000105778]
|
| AlphaFold |
A2A7B5 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000105778
AA Change: S1404P
PolyPhen 2
Score 0.734 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000101404
Gene: ENSMUSG00000057637
AA Change: S1404P
| Domain | Start | End | E-Value | Type |
|---|
|
SET
|
29 |
146 |
2.79e-21 |
SMART |
|
coiled coil region
|
254 |
293 |
N/A |
INTRINSIC |
|
low complexity region
|
333 |
346 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
356 |
378 |
2.95e-3 |
SMART |
|
ZnF_C2H2
|
386 |
408 |
4.79e-3 |
SMART |
|
ZnF_C2H2
|
477 |
500 |
4.17e-3 |
SMART |
|
low complexity region
|
517 |
528 |
N/A |
INTRINSIC |
|
low complexity region
|
653 |
669 |
N/A |
INTRINSIC |
|
low complexity region
|
682 |
697 |
N/A |
INTRINSIC |
|
low complexity region
|
726 |
744 |
N/A |
INTRINSIC |
|
low complexity region
|
868 |
877 |
N/A |
INTRINSIC |
|
low complexity region
|
931 |
951 |
N/A |
INTRINSIC |
|
low complexity region
|
954 |
992 |
N/A |
INTRINSIC |
|
low complexity region
|
1011 |
1032 |
N/A |
INTRINSIC |
|
low complexity region
|
1035 |
1080 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1126 |
1148 |
3.52e-1 |
SMART |
|
ZnF_C2H2
|
1154 |
1177 |
7.55e-1 |
SMART |
|
ZnF_C2H2
|
1183 |
1206 |
4.72e-2 |
SMART |
|
low complexity region
|
1239 |
1253 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1324 |
1344 |
5.12e1 |
SMART |
|
low complexity region
|
1406 |
1423 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1446 |
1466 |
1.86e1 |
SMART |
|
low complexity region
|
1475 |
1507 |
N/A |
INTRINSIC |
|
low complexity region
|
1551 |
1568 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000197026
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
PHENOTYPE: Homozygous null mice have shortened life spans, becoming moribund due to increased incidence of tumors. Mice had a broad spectrum of unusual tumors in multiple organs, with a high incidence of diffuse large B cell lymphomas. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 73 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam25 |
T |
A |
8: 41,208,239 (GRCm39) |
Y502N |
probably damaging |
Het |
| Adam6a |
T |
A |
12: 113,509,484 (GRCm39) |
L619* |
probably null |
Het |
| Akap9 |
A |
T |
5: 4,011,587 (GRCm39) |
R763S |
probably benign |
Het |
| Akt3 |
G |
A |
1: 176,958,639 (GRCm39) |
P24S |
probably damaging |
Het |
| Ano2 |
A |
T |
6: 125,857,382 (GRCm39) |
|
probably null |
Het |
| B4galnt4 |
G |
A |
7: 140,647,957 (GRCm39) |
R491Q |
possibly damaging |
Het |
| Bahcc1 |
A |
G |
11: 120,163,286 (GRCm39) |
D528G |
possibly damaging |
Het |
| Camk1g |
G |
T |
1: 193,030,483 (GRCm39) |
Q409K |
probably benign |
Het |
| Cdh3 |
T |
A |
8: 107,274,396 (GRCm39) |
N638K |
probably benign |
Het |
| Cgnl1 |
T |
A |
9: 71,562,632 (GRCm39) |
E882D |
possibly damaging |
Het |
| Cplane1 |
A |
G |
15: 8,231,785 (GRCm39) |
N1077S |
possibly damaging |
Het |
| Cpxm2 |
C |
T |
7: 131,661,651 (GRCm39) |
E379K |
probably damaging |
Het |
| Cyp3a16 |
A |
G |
5: 145,389,690 (GRCm39) |
L225P |
probably damaging |
Het |
| Dchs1 |
T |
C |
7: 105,411,625 (GRCm39) |
E1497G |
probably damaging |
Het |
| Denr |
T |
A |
5: 124,065,117 (GRCm39) |
S157T |
possibly damaging |
Het |
| Disp3 |
A |
G |
4: 148,356,101 (GRCm39) |
I253T |
probably damaging |
Het |
| Dlgap2 |
C |
T |
8: 14,896,653 (GRCm39) |
T1043M |
probably damaging |
Het |
| Epb41l5 |
T |
C |
1: 119,535,804 (GRCm39) |
T355A |
probably damaging |
Het |
| Etv6 |
G |
A |
6: 134,013,062 (GRCm39) |
|
probably benign |
Het |
| Fbn1 |
T |
C |
2: 125,310,484 (GRCm39) |
I141V |
probably benign |
Het |
| Fsip2 |
T |
G |
2: 82,819,272 (GRCm39) |
S5002A |
probably benign |
Het |
| Gbf1 |
T |
G |
19: 46,271,837 (GRCm39) |
V1576G |
probably damaging |
Het |
| Gmfg |
T |
A |
7: 28,140,733 (GRCm39) |
|
probably null |
Het |
| Gsdmc4 |
T |
C |
15: 63,774,706 (GRCm39) |
E25G |
possibly damaging |
Het |
| Igkv6-23 |
A |
T |
6: 70,237,884 (GRCm39) |
L12M |
possibly damaging |
Het |
| Kank1 |
G |
A |
19: 25,388,138 (GRCm39) |
V604M |
probably damaging |
Het |
| Kctd1 |
A |
G |
18: 15,140,822 (GRCm39) |
V40A |
probably damaging |
Het |
| Krt222 |
T |
C |
11: 99,127,065 (GRCm39) |
K185R |
possibly damaging |
Het |
| Ldc1 |
A |
G |
4: 130,115,527 (GRCm39) |
V7A |
probably benign |
Het |
| Lipm |
T |
C |
19: 34,089,494 (GRCm39) |
F151L |
probably damaging |
Het |
| Lrrc2 |
A |
T |
9: 110,791,710 (GRCm39) |
N154I |
probably damaging |
Het |
| Map1a |
T |
A |
2: 121,132,865 (GRCm39) |
M1227K |
probably damaging |
Het |
| Med1 |
T |
C |
11: 98,071,114 (GRCm39) |
T78A |
probably damaging |
Het |
| Mrm1 |
A |
G |
11: 84,710,144 (GRCm39) |
S19P |
possibly damaging |
Het |
| Naf1 |
GCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCCGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCCGCCAGCCCCGAACTGGGATGCGGGCGGAAGACCACCACCGCCGCCAGCCCCGAACTCGGATCCCGGCGGAAGACC |
GCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCTGCCAGCCCCGAACTCGGATCCCGGCGGAAGACCACCGCCGCCGCCAGCCCCGAGCTCGGATCCCGGCGGAAGACCACCGCCGCCGCCAGCCCCGAACTGGGATGCGGGCGGAAGACCACCACCGCCGCCAGCCCCGAACTCGGATCCCGGCGGAAGACC |
8: 67,313,200 (GRCm39) |
|
probably benign |
Het |
| Nap1l1 |
A |
G |
10: 111,330,657 (GRCm39) |
Y354C |
probably damaging |
Het |
| Npr1 |
A |
G |
3: 90,368,448 (GRCm39) |
V474A |
probably benign |
Het |
| Nyap1 |
A |
T |
5: 137,733,840 (GRCm39) |
S398T |
probably damaging |
Het |
| Obox7 |
C |
T |
7: 14,398,067 (GRCm39) |
Q36* |
probably null |
Het |
| Or5aq6 |
A |
T |
2: 86,923,390 (GRCm39) |
M117K |
possibly damaging |
Het |
| Or6c8 |
A |
T |
10: 128,915,358 (GRCm39) |
I158N |
probably benign |
Het |
| P3h1 |
T |
A |
4: 119,090,428 (GRCm39) |
L92H |
probably benign |
Het |
| Pappa2 |
T |
C |
1: 158,609,818 (GRCm39) |
T1548A |
possibly damaging |
Het |
| Pnisr |
A |
G |
4: 21,873,586 (GRCm39) |
E443G |
probably damaging |
Het |
| Prom1 |
A |
T |
5: 44,190,284 (GRCm39) |
|
probably null |
Het |
| Rbm27 |
A |
T |
18: 42,455,186 (GRCm39) |
Q646H |
probably damaging |
Het |
| Scamp3 |
C |
T |
3: 89,087,561 (GRCm39) |
R134* |
probably null |
Het |
| Scrt2 |
T |
C |
2: 151,924,018 (GRCm39) |
C17R |
probably benign |
Het |
| Setbp1 |
A |
G |
18: 78,902,498 (GRCm39) |
S390P |
probably benign |
Het |
| Shank2 |
A |
T |
7: 143,964,837 (GRCm39) |
D815V |
probably damaging |
Het |
| Sirt7 |
G |
A |
11: 120,511,296 (GRCm39) |
T285M |
|
Het |
| Sis |
T |
G |
3: 72,863,621 (GRCm39) |
S206R |
probably benign |
Het |
| Slc24a4 |
T |
G |
12: 102,193,334 (GRCm39) |
D206E |
possibly damaging |
Het |
| Slc26a4 |
C |
A |
12: 31,585,292 (GRCm39) |
G501C |
probably damaging |
Het |
| Sptb |
T |
C |
12: 76,677,489 (GRCm39) |
N115S |
probably damaging |
Het |
| Srprb |
T |
C |
9: 103,074,807 (GRCm39) |
T112A |
possibly damaging |
Het |
| Tbk1 |
G |
T |
10: 121,389,841 (GRCm39) |
A537E |
probably benign |
Het |
| Tbx19 |
T |
A |
1: 164,970,067 (GRCm39) |
H274L |
probably damaging |
Het |
| Tmem130 |
A |
G |
5: 144,674,233 (GRCm39) |
S394P |
probably damaging |
Het |
| Tmem40 |
A |
G |
6: 115,718,517 (GRCm39) |
S104P |
possibly damaging |
Het |
| Tmprss2 |
T |
A |
16: 97,379,826 (GRCm39) |
Q158L |
probably damaging |
Het |
| Tnip1 |
A |
T |
11: 54,828,876 (GRCm39) |
V97D |
possibly damaging |
Het |
| Tpr |
T |
A |
1: 150,314,887 (GRCm39) |
S1985T |
probably benign |
Het |
| Traf7 |
CA |
CAA |
17: 24,746,737 (GRCm39) |
|
probably benign |
Het |
| Trio |
G |
T |
15: 27,744,158 (GRCm39) |
N2591K |
possibly damaging |
Het |
| Ushbp1 |
A |
T |
8: 71,838,573 (GRCm39) |
C618S |
possibly damaging |
Het |
| Usp34 |
A |
G |
11: 23,317,385 (GRCm39) |
S834G |
possibly damaging |
Het |
| Vmn2r103 |
C |
A |
17: 20,019,525 (GRCm39) |
C536* |
probably null |
Het |
| Vmn2r124 |
T |
A |
17: 18,293,758 (GRCm39) |
V615D |
probably damaging |
Het |
| Zbtb38 |
G |
A |
9: 96,570,397 (GRCm39) |
T229I |
probably benign |
Het |
| Zfhx4 |
T |
A |
3: 5,465,656 (GRCm39) |
V1963E |
probably damaging |
Het |
| Zfp142 |
G |
A |
1: 74,610,933 (GRCm39) |
T954M |
probably benign |
Het |
| Zgrf1 |
A |
G |
3: 127,409,216 (GRCm39) |
Y1730C |
probably benign |
Het |
|
| Other mutations in Prdm2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00530:Prdm2
|
APN |
4 |
142,860,329 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00843:Prdm2
|
APN |
4 |
142,860,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01419:Prdm2
|
APN |
4 |
142,860,218 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01662:Prdm2
|
APN |
4 |
142,860,138 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL01892:Prdm2
|
APN |
4 |
142,860,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02104:Prdm2
|
APN |
4 |
142,859,997 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02208:Prdm2
|
APN |
4 |
142,862,313 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02260:Prdm2
|
APN |
4 |
142,861,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02479:Prdm2
|
APN |
4 |
142,861,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02943:Prdm2
|
APN |
4 |
142,858,542 (GRCm39) |
missense |
probably benign |
|
|
IGL02972:Prdm2
|
APN |
4 |
142,858,736 (GRCm39) |
missense |
probably benign |
|
|
IGL03038:Prdm2
|
APN |
4 |
142,860,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03399:Prdm2
|
APN |
4 |
142,861,658 (GRCm39) |
missense |
probably benign |
0.07 |
|
G1patch:Prdm2
|
UTSW |
4 |
142,859,471 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
PIT4677001:Prdm2
|
UTSW |
4 |
142,861,648 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0088:Prdm2
|
UTSW |
4 |
142,861,524 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0153:Prdm2
|
UTSW |
4 |
142,860,338 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0320:Prdm2
|
UTSW |
4 |
142,905,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0384:Prdm2
|
UTSW |
4 |
142,862,258 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0400:Prdm2
|
UTSW |
4 |
142,838,240 (GRCm39) |
missense |
probably benign |
|
|
R0658:Prdm2
|
UTSW |
4 |
142,861,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0850:Prdm2
|
UTSW |
4 |
142,858,773 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1118:Prdm2
|
UTSW |
4 |
142,858,953 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R1355:Prdm2
|
UTSW |
4 |
142,858,533 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1519:Prdm2
|
UTSW |
4 |
142,862,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1936:Prdm2
|
UTSW |
4 |
142,861,032 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1987:Prdm2
|
UTSW |
4 |
142,859,079 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2006:Prdm2
|
UTSW |
4 |
142,858,447 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2008:Prdm2
|
UTSW |
4 |
142,861,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2030:Prdm2
|
UTSW |
4 |
142,859,334 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R2112:Prdm2
|
UTSW |
4 |
142,858,506 (GRCm39) |
missense |
probably benign |
|
|
R2221:Prdm2
|
UTSW |
4 |
142,861,469 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R2223:Prdm2
|
UTSW |
4 |
142,861,469 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R2426:Prdm2
|
UTSW |
4 |
142,838,320 (GRCm39) |
nonsense |
probably null |
|
|
R2430:Prdm2
|
UTSW |
4 |
142,859,733 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2484:Prdm2
|
UTSW |
4 |
142,861,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3735:Prdm2
|
UTSW |
4 |
142,860,929 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3944:Prdm2
|
UTSW |
4 |
142,858,385 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R4209:Prdm2
|
UTSW |
4 |
142,861,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4411:Prdm2
|
UTSW |
4 |
142,860,240 (GRCm39) |
missense |
probably benign |
0.18 |
|
R4647:Prdm2
|
UTSW |
4 |
142,859,525 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4898:Prdm2
|
UTSW |
4 |
142,860,761 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5032:Prdm2
|
UTSW |
4 |
142,905,937 (GRCm39) |
nonsense |
probably null |
|
|
R5181:Prdm2
|
UTSW |
4 |
142,861,536 (GRCm39) |
missense |
probably benign |
0.35 |
|
R5513:Prdm2
|
UTSW |
4 |
142,862,463 (GRCm39) |
small deletion |
probably benign |
|
|
R5539:Prdm2
|
UTSW |
4 |
142,859,264 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5563:Prdm2
|
UTSW |
4 |
142,861,200 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5618:Prdm2
|
UTSW |
4 |
142,860,107 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5900:Prdm2
|
UTSW |
4 |
142,861,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5990:Prdm2
|
UTSW |
4 |
142,896,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6148:Prdm2
|
UTSW |
4 |
142,859,477 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6166:Prdm2
|
UTSW |
4 |
142,861,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6223:Prdm2
|
UTSW |
4 |
142,868,777 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6530:Prdm2
|
UTSW |
4 |
142,860,617 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6631:Prdm2
|
UTSW |
4 |
142,861,454 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6725:Prdm2
|
UTSW |
4 |
142,859,471 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6847:Prdm2
|
UTSW |
4 |
142,859,520 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7193:Prdm2
|
UTSW |
4 |
142,907,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Prdm2
|
UTSW |
4 |
142,862,391 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7292:Prdm2
|
UTSW |
4 |
142,859,471 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R7417:Prdm2
|
UTSW |
4 |
142,905,869 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7748:Prdm2
|
UTSW |
4 |
142,862,459 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7885:Prdm2
|
UTSW |
4 |
142,861,140 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7936:Prdm2
|
UTSW |
4 |
142,862,434 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7976:Prdm2
|
UTSW |
4 |
142,859,812 (GRCm39) |
nonsense |
probably null |
|
|
R8124:Prdm2
|
UTSW |
4 |
142,861,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8150:Prdm2
|
UTSW |
4 |
142,859,303 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8156:Prdm2
|
UTSW |
4 |
142,861,338 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8178:Prdm2
|
UTSW |
4 |
142,859,018 (GRCm39) |
missense |
probably benign |
0.33 |
|
R8235:Prdm2
|
UTSW |
4 |
142,859,037 (GRCm39) |
nonsense |
probably null |
|
|
R8404:Prdm2
|
UTSW |
4 |
142,861,584 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8498:Prdm2
|
UTSW |
4 |
142,907,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8502:Prdm2
|
UTSW |
4 |
142,861,584 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8688:Prdm2
|
UTSW |
4 |
142,838,310 (GRCm39) |
missense |
probably benign |
|
|
R8732:Prdm2
|
UTSW |
4 |
142,862,580 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8796:Prdm2
|
UTSW |
4 |
142,860,017 (GRCm39) |
missense |
probably benign |
0.33 |
|
R8874:Prdm2
|
UTSW |
4 |
142,859,785 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8887:Prdm2
|
UTSW |
4 |
142,860,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9119:Prdm2
|
UTSW |
4 |
142,858,449 (GRCm39) |
nonsense |
probably null |
|
|
R9139:Prdm2
|
UTSW |
4 |
142,858,752 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9165:Prdm2
|
UTSW |
4 |
142,858,674 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9342:Prdm2
|
UTSW |
4 |
142,861,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9518:Prdm2
|
UTSW |
4 |
142,860,579 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9546:Prdm2
|
UTSW |
4 |
142,861,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9547:Prdm2
|
UTSW |
4 |
142,861,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9730:Prdm2
|
UTSW |
4 |
142,858,659 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
X0017:Prdm2
|
UTSW |
4 |
142,861,277 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TATTCAGGCTGCCGATGTAC -3'
(R):5'- TGGCAAGAGTGTTGATAACATGC -3'
Sequencing Primer
(F):5'- TGCCGATGTACGTGAACTC -3'
(R):5'- TGATAACATGCCTGAGCTGC -3'
|
| Posted On |
2022-10-06 |
Incidental Mutation