Mutagenetix > Incidental Mutation

Incidental Mutation 'R9691:Ahnak'

729190

Institutional Source

Beutler Lab

Gene Symbol

Ahnak

Ensembl Gene

ENSMUSG00000069833

Gene Name

AHNAK nucleoprotein

Synonyms

DY6, 1110004P15Rik, 2310047C17Rik

MMRRC Submission

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.313) question?

Stock #

R9691 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

8966648-9054278 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 8989090 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Methionine to Threonine at position 3458 (M3458T)

Ref Sequence

ENSEMBL: ENSMUSP00000090633 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000092955] [ENSMUST00000092956]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000092955

SMART Domains

Protein: ENSMUSP00000090632
Gene: ENSMUSG00000069833

Domain	Start	End	E-Value	Type
low complexity region	2	13	N/A	INTRINSIC
PDZ	20	91	2.31e-5	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000092956
AA Change: M3458T

PolyPhen 2 Score 0.486 (Sensitivity: 0.88; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000090633
Gene: ENSMUSG00000069833
AA Change: M3458T

Domain	Start	End	E-Value	Type
low complexity region	2	13	N/A	INTRINSIC
PDZ	20	91	2.31e-5	SMART
internal_repeat_2	163	1515	5.22e-182	PROSPERO
internal_repeat_1	224	2314	N/A	PROSPERO
internal_repeat_2	1532	3028	5.22e-182	PROSPERO
internal_repeat_1	2660	5095	N/A	PROSPERO
low complexity region	5336	5353	N/A	INTRINSIC
low complexity region	5493	5504	N/A	INTRINSIC
low complexity region	5580	5600	N/A	INTRINSIC
low complexity region	5620	5636	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.0%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. [provided by RefSeq, Oct 2016]
PHENOTYPE: Mice homozygous for one knock-out allele exhibit decreased T cell proliferation and increased susceptibility to parasitic infection. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 62 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Akap9	T	G	5: 4,010,491 (GRCm39)	L398R	probably damaging	Het
Anks3	A	T	16: 4,759,840 (GRCm39)	C635S	probably benign	Het
Ankzf1	C	A	1: 75,175,196 (GRCm39)	Q649K	probably benign	Het
Atp8a2	T	C	14: 60,245,829 (GRCm39)	E621G	probably damaging	Het
Bscl2	A	G	19: 8,817,110 (GRCm39)	T13A	probably benign	Het
Cd109	T	C	9: 78,611,074 (GRCm39)	L1230P	possibly damaging	Het
Celsr2	T	A	3: 108,301,551 (GRCm39)	S2678C	probably damaging	Het
Cnot10	A	G	9: 114,420,715 (GRCm39)	L709P	probably damaging	Het
Col5a1	G	A	2: 27,842,994 (GRCm39)	R449Q	unknown	Het
Cyp3a25	T	A	5: 145,931,732 (GRCm39)	E125D	probably benign	Het
Ddx50	T	G	10: 62,476,524 (GRCm39)	I250L	probably benign	Het
Dnah10	A	G	5: 124,852,249 (GRCm39)	N1859S	probably damaging	Het
Dnajc13	A	G	9: 104,042,211 (GRCm39)	L2008P	probably damaging	Het
Dock4	C	T	12: 40,686,097 (GRCm39)	L111F	probably damaging	Het
Ffar3	C	G	7: 30,555,119 (GRCm39)	R67P	probably damaging	Het
Gdap2	C	T	3: 100,109,441 (GRCm39)	A486V	probably benign	Het
Gm45871	G	A	18: 90,610,111 (GRCm39)	V450M	possibly damaging	Het
Golgb1	T	A	16: 36,718,996 (GRCm39)	S342T	probably damaging	Het
Grip1	G	A	10: 119,874,569 (GRCm39)	E778K	possibly damaging	Het
Grm5	T	C	7: 87,723,903 (GRCm39)	I731T	probably damaging	Het
Gxylt2	A	T	6: 100,760,109 (GRCm39)	T215S	probably damaging	Het
Jakmip2	A	T	18: 43,673,685 (GRCm39)	I793N	probably damaging	Het
Kcnc1	C	A	7: 46,076,955 (GRCm39)	C252*	probably null	Het
Kdr	T	A	5: 76,129,521 (GRCm39)	D122V	probably damaging	Het
Kmt2a	G	A	9: 44,731,557 (GRCm39)	P2920L	unknown	Het
Lrrc31	T	C	3: 30,741,617 (GRCm39)	E264G	probably damaging	Het
Mbnl1	A	G	3: 60,529,614 (GRCm39)	T256A	probably benign	Het
Myh3	A	G	11: 66,991,921 (GRCm39)	E1822G	possibly damaging	Het
Ndst4	A	G	3: 125,518,344 (GRCm39)	N155S	unknown	Het
Negr1	T	C	3: 156,267,898 (GRCm39)	C23R	probably damaging	Het
Nfia	T	A	4: 97,671,465 (GRCm39)	D58E	probably damaging	Het
Nrp1	A	T	8: 129,202,650 (GRCm39)	N545I	probably damaging	Het
Nrtn	T	A	17: 57,059,480 (GRCm39)		probably benign	Het
Or2a14	A	G	6: 43,130,629 (GRCm39)	H130R	probably benign	Het
Or4c100	T	C	2: 88,356,421 (GRCm39)	F165L	probably benign	Het
Or5an11	C	T	19: 12,246,379 (GRCm39)	R262*	probably null	Het
Pclo	G	A	5: 14,727,558 (GRCm39)	D2139N	unknown	Het
Phlpp1	C	T	1: 106,246,699 (GRCm39)	Q630*	probably null	Het
Pkd1	T	C	17: 24,796,812 (GRCm39)	V2429A	possibly damaging	Het
Pramel20	T	A	4: 143,299,328 (GRCm39)	H330Q	probably benign	Het
Pramel30	T	C	4: 144,056,844 (GRCm39)	L9P	probably damaging	Het
Prkch	A	G	12: 73,805,730 (GRCm39)	K502E	probably damaging	Het
Rad51ap2	A	G	12: 11,509,413 (GRCm39)	K930E	possibly damaging	Het
Reep4	T	A	14: 70,785,683 (GRCm39)	N204K	probably benign	Het
Rin2	T	C	2: 145,690,764 (GRCm39)	L144P	probably damaging	Het
Scfd2	T	C	5: 74,691,611 (GRCm39)	S224G	possibly damaging	Het
Srprb	A	G	9: 103,069,481 (GRCm39)	Y158H	probably damaging	Het
Thbs4	T	A	13: 92,890,896 (GRCm39)	H857L	probably damaging	Het
Tmem184a	A	G	5: 139,798,790 (GRCm39)	L77P	possibly damaging	Het
Trbv26	G	T	6: 41,204,478 (GRCm39)	C7F	probably benign	Het
Trip11	A	G	12: 101,850,123 (GRCm39)	S1314P	probably benign	Het
Ttc28	A	T	5: 111,431,879 (GRCm39)	T1951S	probably benign	Het
Ttc29	A	C	8: 78,972,895 (GRCm39)	D115A	possibly damaging	Het
Upf2	G	A	2: 6,032,024 (GRCm39)	V857I	unknown	Het
Vmn2r43	A	G	7: 8,247,787 (GRCm39)	V792A	probably damaging	Het
Washc5	A	T	15: 59,218,706 (GRCm39)	I687N	probably damaging	Het
Wwc2	G	A	8: 48,281,799 (GRCm39)		probably benign	Het
Xirp2	G	A	2: 67,340,539 (GRCm39)	E927K	possibly damaging	Het
Zc3hav1l	A	G	6: 38,276,112 (GRCm39)	F22L	probably benign	Het
Zfp407	C	T	18: 84,578,312 (GRCm39)	A934T	probably benign	Het
Zfp986	T	A	4: 145,626,070 (GRCm39)	S243R	probably benign	Het
Zfyve9	T	C	4: 108,576,305 (GRCm39)	T259A	probably benign	Het

Other mutations in Ahnak

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00467:Ahnak	APN	19	8,984,587 (GRCm39)	missense	probably damaging	0.99
IGL00509:Ahnak	APN	19	8,987,315 (GRCm39)	missense	possibly damaging	0.94
IGL00539:Ahnak	APN	19	8,985,272 (GRCm39)	missense	possibly damaging	0.50
IGL00558:Ahnak	APN	19	8,981,671 (GRCm39)	missense	possibly damaging	0.93
IGL00567:Ahnak	APN	19	8,990,747 (GRCm39)	missense	probably benign	0.24
IGL00706:Ahnak	APN	19	8,991,094 (GRCm39)	nonsense	probably null
IGL00807:Ahnak	APN	19	8,985,886 (GRCm39)	missense	possibly damaging	0.92
IGL00870:Ahnak	APN	19	8,991,062 (GRCm39)	missense	probably damaging	1.00
IGL01101:Ahnak	APN	19	8,990,251 (GRCm39)	intron	probably benign
IGL01118:Ahnak	APN	19	8,989,942 (GRCm39)	missense	probably damaging	1.00
IGL01288:Ahnak	APN	19	8,979,858 (GRCm39)	missense	possibly damaging	0.94
IGL01324:Ahnak	APN	19	8,980,396 (GRCm39)	missense	probably damaging	1.00
IGL01341:Ahnak	APN	19	8,989,067 (GRCm39)	missense	probably benign
IGL01541:Ahnak	APN	19	8,985,243 (GRCm39)	missense	possibly damaging	0.95
IGL01580:Ahnak	APN	19	8,980,203 (GRCm39)	missense	probably benign	0.02
IGL01595:Ahnak	APN	19	8,980,865 (GRCm39)	nonsense	probably null
IGL01746:Ahnak	APN	19	8,982,276 (GRCm39)	missense	possibly damaging	0.89
IGL01766:Ahnak	APN	19	8,977,482 (GRCm39)	missense	unknown
IGL01821:Ahnak	APN	19	8,989,482 (GRCm39)	missense	probably benign
IGL01913:Ahnak	APN	19	8,983,428 (GRCm39)	nonsense	probably null
IGL01934:Ahnak	APN	19	8,980,021 (GRCm39)	missense	probably damaging	1.00
IGL01940:Ahnak	APN	19	8,983,921 (GRCm39)	missense	probably benign	0.14
IGL01958:Ahnak	APN	19	8,992,273 (GRCm39)	missense	possibly damaging	0.59
IGL02145:Ahnak	APN	19	8,980,219 (GRCm39)	missense	probably benign	0.11
IGL02246:Ahnak	APN	19	8,985,632 (GRCm39)	missense	probably damaging	1.00
IGL02282:Ahnak	APN	19	8,983,351 (GRCm39)	missense	probably damaging	1.00
IGL02428:Ahnak	APN	19	8,992,197 (GRCm39)	missense	possibly damaging	0.83
IGL02442:Ahnak	APN	19	8,981,380 (GRCm39)	missense	probably damaging	1.00
IGL02474:Ahnak	APN	19	8,982,297 (GRCm39)	missense	probably benign	0.13
IGL02483:Ahnak	APN	19	8,980,672 (GRCm39)	missense	probably benign	0.01
IGL02616:Ahnak	APN	19	8,982,991 (GRCm39)	missense	probably benign	0.03
IGL02630:Ahnak	APN	19	8,989,441 (GRCm39)	missense	probably damaging	1.00
IGL02690:Ahnak	APN	19	8,989,948 (GRCm39)	nonsense	probably null
IGL02717:Ahnak	APN	19	8,979,751 (GRCm39)	missense	probably benign	0.00
IGL02721:Ahnak	APN	19	8,987,071 (GRCm39)	missense	probably benign	0.07
IGL02737:Ahnak	APN	19	8,981,957 (GRCm39)	missense	probably benign	0.17
IGL02850:Ahnak	APN	19	8,979,960 (GRCm39)	missense	probably benign	0.00
IGL03071:Ahnak	APN	19	8,989,282 (GRCm39)	missense	possibly damaging	0.63
IGL03072:Ahnak	APN	19	8,983,872 (GRCm39)	missense	probably benign	0.11
IGL03094:Ahnak	APN	19	8,980,911 (GRCm39)	missense	possibly damaging	0.64
IGL03140:Ahnak	APN	19	8,982,576 (GRCm39)	intron	probably benign
IGL03176:Ahnak	APN	19	8,979,813 (GRCm39)	missense	probably damaging	1.00
IGL03176:Ahnak	APN	19	8,985,530 (GRCm39)	missense	possibly damaging	0.56
IGL03189:Ahnak	APN	19	8,988,603 (GRCm39)	missense	possibly damaging	0.65
IGL03357:Ahnak	APN	19	8,986,689 (GRCm39)	intron	probably benign
IGL03371:Ahnak	APN	19	8,981,592 (GRCm39)	missense	possibly damaging	0.91
Eskimo	UTSW	19	8,986,938 (GRCm39)	missense	probably benign	0.31
Nanook	UTSW	19	8,980,595 (GRCm39)	missense	probably benign	0.42
Netsilik	UTSW	19	8,979,685 (GRCm39)	missense	probably benign	0.00
IGL03097:Ahnak	UTSW	19	8,979,751 (GRCm39)	missense	probably benign	0.00
PIT4403001:Ahnak	UTSW	19	8,983,540 (GRCm39)	missense	possibly damaging	0.87
R0054:Ahnak	UTSW	19	8,989,420 (GRCm39)	missense	probably damaging	1.00
R0094:Ahnak	UTSW	19	8,991,257 (GRCm39)	missense	probably benign	0.12
R0110:Ahnak	UTSW	19	8,995,596 (GRCm39)	nonsense	probably null
R0141:Ahnak	UTSW	19	8,984,044 (GRCm39)	missense	probably damaging	1.00
R0166:Ahnak	UTSW	19	8,983,089 (GRCm39)	missense	probably damaging	1.00
R0309:Ahnak	UTSW	19	8,979,859 (GRCm39)	missense	probably damaging	1.00
R0368:Ahnak	UTSW	19	8,985,714 (GRCm39)	nonsense	probably null
R0386:Ahnak	UTSW	19	8,988,508 (GRCm39)	missense	possibly damaging	0.94
R0401:Ahnak	UTSW	19	8,992,480 (GRCm39)	missense	probably benign	0.24
R0415:Ahnak	UTSW	19	8,990,235 (GRCm39)	intron	probably benign
R0463:Ahnak	UTSW	19	8,986,771 (GRCm39)	intron	probably benign
R0469:Ahnak	UTSW	19	8,995,596 (GRCm39)	nonsense	probably null
R0470:Ahnak	UTSW	19	8,986,331 (GRCm39)	missense	probably benign	0.29
R0487:Ahnak	UTSW	19	8,991,484 (GRCm39)	missense	probably damaging	0.99
R0487:Ahnak	UTSW	19	8,984,515 (GRCm39)	missense	probably benign	0.00
R0499:Ahnak	UTSW	19	8,977,628 (GRCm39)	splice site	probably benign
R0506:Ahnak	UTSW	19	8,986,492 (GRCm39)	missense	probably damaging	1.00
R0510:Ahnak	UTSW	19	8,995,596 (GRCm39)	nonsense	probably null
R0557:Ahnak	UTSW	19	8,979,308 (GRCm39)	missense	probably benign	0.10
R0570:Ahnak	UTSW	19	8,991,062 (GRCm39)	missense	probably damaging	1.00
R0610:Ahnak	UTSW	19	8,985,242 (GRCm39)	missense	probably benign	0.08
R0646:Ahnak	UTSW	19	8,990,766 (GRCm39)	nonsense	probably null
R0659:Ahnak	UTSW	19	8,992,366 (GRCm39)	missense	possibly damaging	0.60
R0791:Ahnak	UTSW	19	8,994,098 (GRCm39)	missense	probably benign	0.01
R0792:Ahnak	UTSW	19	8,994,098 (GRCm39)	missense	probably benign	0.01
R0840:Ahnak	UTSW	19	8,982,427 (GRCm39)	missense	probably damaging	1.00
R0847:Ahnak	UTSW	19	8,983,797 (GRCm39)	nonsense	probably null
R0941:Ahnak	UTSW	19	8,987,278 (GRCm39)	missense	probably damaging	1.00
R0962:Ahnak	UTSW	19	8,990,212 (GRCm39)	intron	probably benign
R1017:Ahnak	UTSW	19	8,987,907 (GRCm39)	missense	probably damaging	0.99
R1037:Ahnak	UTSW	19	8,984,982 (GRCm39)	missense	probably benign	0.27
R1085:Ahnak	UTSW	19	8,990,489 (GRCm39)	missense	possibly damaging	0.50
R1113:Ahnak	UTSW	19	8,982,984 (GRCm39)	missense	probably benign	0.29
R1140:Ahnak	UTSW	19	8,981,609 (GRCm39)	missense	probably damaging	1.00
R1158:Ahnak	UTSW	19	8,991,290 (GRCm39)	missense	probably benign	0.00
R1218:Ahnak	UTSW	19	8,992,983 (GRCm39)	missense	probably damaging	1.00
R1225:Ahnak	UTSW	19	8,980,247 (GRCm39)	missense	probably damaging	1.00
R1245:Ahnak	UTSW	19	8,981,533 (GRCm39)	missense	probably benign	0.44
R1421:Ahnak	UTSW	19	8,992,995 (GRCm39)	missense	possibly damaging	0.95
R1447:Ahnak	UTSW	19	8,984,446 (GRCm39)	missense	probably damaging	0.98
R1464:Ahnak	UTSW	19	8,982,260 (GRCm39)	missense	probably damaging	1.00
R1464:Ahnak	UTSW	19	8,982,260 (GRCm39)	missense	probably damaging	1.00
R1466:Ahnak	UTSW	19	8,993,239 (GRCm39)	missense	probably damaging	1.00
R1466:Ahnak	UTSW	19	8,993,239 (GRCm39)	missense	probably damaging	1.00
R1471:Ahnak	UTSW	19	8,990,296 (GRCm39)	intron	probably benign
R1507:Ahnak	UTSW	19	8,987,441 (GRCm39)	missense	probably damaging	1.00
R1521:Ahnak	UTSW	19	8,982,092 (GRCm39)	missense	probably benign	0.11
R1568:Ahnak	UTSW	19	8,979,739 (GRCm39)	missense	probably damaging	0.98
R1569:Ahnak	UTSW	19	8,981,458 (GRCm39)	missense	possibly damaging	0.78
R1616:Ahnak	UTSW	19	8,986,351 (GRCm39)	missense	possibly damaging	0.94
R1638:Ahnak	UTSW	19	8,986,813 (GRCm39)	missense	probably benign	0.01
R1680:Ahnak	UTSW	19	8,987,327 (GRCm39)	missense	probably benign	0.05
R1713:Ahnak	UTSW	19	8,989,173 (GRCm39)	missense	possibly damaging	0.95
R1722:Ahnak	UTSW	19	8,988,019 (GRCm39)	missense	probably damaging	0.99
R1771:Ahnak	UTSW	19	8,991,117 (GRCm39)	missense	probably benign	0.24
R1795:Ahnak	UTSW	19	8,979,802 (GRCm39)	missense	possibly damaging	0.79
R1823:Ahnak	UTSW	19	8,982,269 (GRCm39)	missense	probably damaging	0.99
R1842:Ahnak	UTSW	19	8,983,231 (GRCm39)	missense	probably damaging	0.99
R1854:Ahnak	UTSW	19	8,991,196 (GRCm39)	missense	possibly damaging	0.61
R1856:Ahnak	UTSW	19	8,979,412 (GRCm39)	missense	possibly damaging	0.86
R1886:Ahnak	UTSW	19	8,993,343 (GRCm39)	missense	probably damaging	0.98
R1888:Ahnak	UTSW	19	8,984,452 (GRCm39)	missense	probably damaging	1.00
R1888:Ahnak	UTSW	19	8,984,452 (GRCm39)	missense	probably damaging	1.00
R1912:Ahnak	UTSW	19	8,995,245 (GRCm39)	missense	probably damaging	1.00
R1913:Ahnak	UTSW	19	8,985,286 (GRCm39)	missense	probably damaging	0.99
R1942:Ahnak	UTSW	19	8,992,447 (GRCm39)	missense	probably damaging	0.98
R1987:Ahnak	UTSW	19	8,992,615 (GRCm39)	missense	probably damaging	1.00
R2006:Ahnak	UTSW	19	8,984,439 (GRCm39)	missense	probably damaging	1.00
R2013:Ahnak	UTSW	19	8,991,937 (GRCm39)	missense	probably damaging	0.98
R2014:Ahnak	UTSW	19	8,990,545 (GRCm39)	missense	probably damaging	0.99
R2047:Ahnak	UTSW	19	8,991,664 (GRCm39)	missense	possibly damaging	0.67
R2048:Ahnak	UTSW	19	8,984,420 (GRCm39)	missense	probably damaging	0.99
R2060:Ahnak	UTSW	19	8,985,405 (GRCm39)	missense	probably benign	0.08
R2083:Ahnak	UTSW	19	8,988,921 (GRCm39)	missense	probably damaging	1.00
R2157:Ahnak	UTSW	19	8,978,048 (GRCm39)	missense	possibly damaging	0.92
R2167:Ahnak	UTSW	19	8,988,858 (GRCm39)	nonsense	probably null
R2208:Ahnak	UTSW	19	8,995,096 (GRCm39)	missense	probably benign	0.00
R2224:Ahnak	UTSW	19	8,990,355 (GRCm39)	intron	probably benign
R2268:Ahnak	UTSW	19	8,987,938 (GRCm39)	missense	possibly damaging	0.66
R2420:Ahnak	UTSW	19	8,986,620 (GRCm39)	missense	possibly damaging	0.89
R2426:Ahnak	UTSW	19	8,980,215 (GRCm39)	missense	possibly damaging	0.81
R2910:Ahnak	UTSW	19	8,989,018 (GRCm39)	missense	probably damaging	0.99
R2911:Ahnak	UTSW	19	8,989,018 (GRCm39)	missense	probably damaging	0.99
R2981:Ahnak	UTSW	19	8,977,512 (GRCm39)	missense	probably damaging	0.97
R3151:Ahnak	UTSW	19	8,987,308 (GRCm39)	missense	probably benign	0.12
R3155:Ahnak	UTSW	19	8,987,541 (GRCm39)	missense	possibly damaging	0.49
R3422:Ahnak	UTSW	19	8,984,116 (GRCm39)	missense	probably benign	0.05
R3422:Ahnak	UTSW	19	8,983,072 (GRCm39)	missense	probably benign	0.39
R3430:Ahnak	UTSW	19	8,984,322 (GRCm39)	missense	probably benign	0.42
R3433:Ahnak	UTSW	19	8,987,358 (GRCm39)	missense	probably benign	0.01
R3711:Ahnak	UTSW	19	8,985,262 (GRCm39)	missense	probably benign
R3723:Ahnak	UTSW	19	8,994,217 (GRCm39)	missense	possibly damaging	0.79
R3775:Ahnak	UTSW	19	8,986,387 (GRCm39)	missense	possibly damaging	0.91
R3858:Ahnak	UTSW	19	8,988,223 (GRCm39)	missense	possibly damaging	0.82
R3859:Ahnak	UTSW	19	8,988,223 (GRCm39)	missense	possibly damaging	0.82
R3922:Ahnak	UTSW	19	8,983,692 (GRCm39)	missense	probably benign	0.20
R3924:Ahnak	UTSW	19	8,983,692 (GRCm39)	missense	probably benign	0.20
R3926:Ahnak	UTSW	19	8,983,692 (GRCm39)	missense	probably benign	0.20
R4026:Ahnak	UTSW	19	8,988,663 (GRCm39)	missense	probably damaging	0.97
R4051:Ahnak	UTSW	19	8,991,691 (GRCm39)	missense	probably damaging	1.00
R4209:Ahnak	UTSW	19	8,979,964 (GRCm39)	missense	probably damaging	1.00
R4234:Ahnak	UTSW	19	8,978,150 (GRCm39)	nonsense	probably null
R4237:Ahnak	UTSW	19	8,979,147 (GRCm39)	missense	probably benign	0.02
R4285:Ahnak	UTSW	19	8,994,203 (GRCm39)	nonsense	probably null
R4331:Ahnak	UTSW	19	8,993,184 (GRCm39)	missense	probably damaging	1.00
R4342:Ahnak	UTSW	19	8,989,447 (GRCm39)	missense	possibly damaging	0.79
R4430:Ahnak	UTSW	19	8,980,404 (GRCm39)	missense	probably benign	0.00
R4554:Ahnak	UTSW	19	8,992,294 (GRCm39)	missense	probably damaging	1.00
R4602:Ahnak	UTSW	19	8,988,189 (GRCm39)	missense	possibly damaging	0.66
R4612:Ahnak	UTSW	19	8,981,088 (GRCm39)	missense	probably benign	0.44
R4655:Ahnak	UTSW	19	8,986,065 (GRCm39)	missense	probably damaging	1.00
R4656:Ahnak	UTSW	19	8,982,219 (GRCm39)	missense	possibly damaging	0.80
R4700:Ahnak	UTSW	19	8,982,045 (GRCm39)	missense	probably benign	0.02
R4704:Ahnak	UTSW	19	8,989,622 (GRCm39)	intron	probably benign
R4704:Ahnak	UTSW	19	8,990,545 (GRCm39)	missense	probably damaging	0.99
R4705:Ahnak	UTSW	19	8,994,270 (GRCm39)	missense	probably benign	0.07
R4707:Ahnak	UTSW	19	8,994,099 (GRCm39)	missense	probably benign	0.03
R4732:Ahnak	UTSW	19	8,984,665 (GRCm39)	missense	probably damaging	1.00
R4733:Ahnak	UTSW	19	8,984,665 (GRCm39)	missense	probably damaging	1.00
R4778:Ahnak	UTSW	19	8,989,339 (GRCm39)	missense	possibly damaging	0.79
R4782:Ahnak	UTSW	19	8,989,863 (GRCm39)	intron	probably benign
R4832:Ahnak	UTSW	19	8,989,824 (GRCm39)	intron	probably benign
R4882:Ahnak	UTSW	19	8,983,261 (GRCm39)	missense	probably damaging	0.98
R4884:Ahnak	UTSW	19	8,990,118 (GRCm39)	intron	probably benign
R4895:Ahnak	UTSW	19	8,994,805 (GRCm39)	missense	probably benign	0.43
R4930:Ahnak	UTSW	19	8,988,331 (GRCm39)	missense	possibly damaging	0.79
R4951:Ahnak	UTSW	19	8,995,199 (GRCm39)	missense	probably damaging	1.00
R4968:Ahnak	UTSW	19	8,992,464 (GRCm39)	missense	probably damaging	1.00
R5026:Ahnak	UTSW	19	8,987,995 (GRCm39)	missense	possibly damaging	0.46
R5050:Ahnak	UTSW	19	8,989,822 (GRCm39)	intron	probably benign
R5073:Ahnak	UTSW	19	8,980,595 (GRCm39)	missense	probably benign	0.42
R5110:Ahnak	UTSW	19	8,992,123 (GRCm39)	missense	probably damaging	1.00
R5119:Ahnak	UTSW	19	8,991,008 (GRCm39)	missense	probably benign	0.00
R5128:Ahnak	UTSW	19	8,994,451 (GRCm39)	missense	probably damaging	1.00
R5139:Ahnak	UTSW	19	8,982,019 (GRCm39)	missense	probably damaging	1.00
R5150:Ahnak	UTSW	19	8,988,268 (GRCm39)	missense	possibly damaging	0.46
R5151:Ahnak	UTSW	19	8,994,933 (GRCm39)	missense	probably benign	0.03
R5165:Ahnak	UTSW	19	8,993,029 (GRCm39)	missense	possibly damaging	0.95
R5236:Ahnak	UTSW	19	8,978,048 (GRCm39)	missense	possibly damaging	0.92
R5361:Ahnak	UTSW	19	8,992,705 (GRCm39)	missense	possibly damaging	0.92
R5366:Ahnak	UTSW	19	8,994,099 (GRCm39)	missense	possibly damaging	0.65
R5387:Ahnak	UTSW	19	8,981,055 (GRCm39)	missense	probably damaging	1.00
R5396:Ahnak	UTSW	19	8,984,539 (GRCm39)	missense	probably damaging	0.99
R5583:Ahnak	UTSW	19	8,984,281 (GRCm39)	missense	probably damaging	0.99
R5587:Ahnak	UTSW	19	8,986,840 (GRCm39)	missense	possibly damaging	0.88
R5620:Ahnak	UTSW	19	8,990,458 (GRCm39)	nonsense	probably null
R5643:Ahnak	UTSW	19	8,988,021 (GRCm39)	missense	possibly damaging	0.66
R5644:Ahnak	UTSW	19	8,988,021 (GRCm39)	missense	possibly damaging	0.66
R5657:Ahnak	UTSW	19	8,991,979 (GRCm39)	missense	probably damaging	0.99
R5688:Ahnak	UTSW	19	8,979,883 (GRCm39)	missense	probably benign	0.01
R5702:Ahnak	UTSW	19	8,979,204 (GRCm39)	missense	probably damaging	1.00
R5727:Ahnak	UTSW	19	8,994,111 (GRCm39)	missense	probably damaging	0.99
R5730:Ahnak	UTSW	19	8,987,617 (GRCm39)	missense	possibly damaging	0.81
R5755:Ahnak	UTSW	19	8,979,096 (GRCm39)	missense	probably benign	0.06
R5760:Ahnak	UTSW	19	8,990,926 (GRCm39)	missense	probably damaging	1.00
R5789:Ahnak	UTSW	19	8,979,685 (GRCm39)	missense	probably benign	0.00
R5790:Ahnak	UTSW	19	8,992,612 (GRCm39)	missense	probably damaging	0.99
R5795:Ahnak	UTSW	19	8,989,746 (GRCm39)	nonsense	probably null
R5808:Ahnak	UTSW	19	8,987,599 (GRCm39)	missense	possibly damaging	0.91
R5867:Ahnak	UTSW	19	8,987,416 (GRCm39)	missense	probably damaging	0.99
R5878:Ahnak	UTSW	19	8,985,706 (GRCm39)	missense	probably damaging	1.00
R5898:Ahnak	UTSW	19	8,995,575 (GRCm39)	missense	probably damaging	1.00
R5898:Ahnak	UTSW	19	8,991,131 (GRCm39)	missense	possibly damaging	0.63
R5912:Ahnak	UTSW	19	8,989,267 (GRCm39)	missense	probably damaging	0.99
R5935:Ahnak	UTSW	19	8,992,546 (GRCm39)	missense	possibly damaging	0.91
R5969:Ahnak	UTSW	19	8,993,949 (GRCm39)	missense	probably damaging	1.00
R5988:Ahnak	UTSW	19	8,986,711 (GRCm39)	intron	probably benign
R6000:Ahnak	UTSW	19	8,990,475 (GRCm39)	nonsense	probably null
R6005:Ahnak	UTSW	19	8,992,525 (GRCm39)	missense	possibly damaging	0.61
R6101:Ahnak	UTSW	19	8,981,463 (GRCm39)	missense	probably benign	0.20
R6105:Ahnak	UTSW	19	8,981,463 (GRCm39)	missense	probably benign	0.20
R6116:Ahnak	UTSW	19	8,990,327 (GRCm39)	intron	probably benign
R6209:Ahnak	UTSW	19	8,989,930 (GRCm39)	missense	probably damaging	1.00
R6240:Ahnak	UTSW	19	8,990,947 (GRCm39)	missense	probably damaging	1.00
R6255:Ahnak	UTSW	19	8,985,389 (GRCm39)	missense	possibly damaging	0.95
R6263:Ahnak	UTSW	19	8,995,641 (GRCm39)	missense	probably benign	0.03
R6287:Ahnak	UTSW	19	8,992,367 (GRCm39)	missense	probably benign	0.02
R6296:Ahnak	UTSW	19	8,980,669 (GRCm39)	missense	probably damaging	0.99
R6315:Ahnak	UTSW	19	8,983,990 (GRCm39)	missense	probably damaging	0.99
R6328:Ahnak	UTSW	19	8,984,512 (GRCm39)	missense	probably benign	0.11
R6331:Ahnak	UTSW	19	8,983,989 (GRCm39)	missense	probably benign	0.18
R6355:Ahnak	UTSW	19	8,986,126 (GRCm39)	missense	probably benign	0.02
R6409:Ahnak	UTSW	19	8,986,938 (GRCm39)	missense	probably benign	0.31
R6567:Ahnak	UTSW	19	8,986,170 (GRCm39)	missense	probably benign	0.27
R6572:Ahnak	UTSW	19	8,985,340 (GRCm39)	missense	probably damaging	0.99
R6574:Ahnak	UTSW	19	8,994,411 (GRCm39)	missense	probably benign	0.04
R6590:Ahnak	UTSW	19	8,986,945 (GRCm39)	missense	probably benign	0.29
R6620:Ahnak	UTSW	19	8,992,674 (GRCm39)	missense	possibly damaging	0.95
R6690:Ahnak	UTSW	19	8,986,945 (GRCm39)	missense	probably benign	0.29
R6731:Ahnak	UTSW	19	8,988,926 (GRCm39)	missense	possibly damaging	0.85
R6756:Ahnak	UTSW	19	8,984,925 (GRCm39)	missense	possibly damaging	0.59
R6846:Ahnak	UTSW	19	8,989,221 (GRCm39)	missense	possibly damaging	0.66
R6854:Ahnak	UTSW	19	8,992,599 (GRCm39)	missense	probably damaging	1.00
R6857:Ahnak	UTSW	19	9,014,532 (GRCm39)	nonsense	probably null
R6863:Ahnak	UTSW	19	8,989,729 (GRCm39)	intron	probably benign
R6876:Ahnak	UTSW	19	8,991,484 (GRCm39)	missense	probably damaging	0.99
R6958:Ahnak	UTSW	19	8,992,579 (GRCm39)	missense	possibly damaging	0.88
R7126:Ahnak	UTSW	19	8,979,723 (GRCm39)	missense	possibly damaging	0.61
R7181:Ahnak	UTSW	19	8,990,852 (GRCm39)	missense	probably damaging	1.00
R7183:Ahnak	UTSW	19	8,995,032 (GRCm39)	missense	probably damaging	1.00
R7202:Ahnak	UTSW	19	8,995,163 (GRCm39)	missense	probably damaging	1.00
R7235:Ahnak	UTSW	19	8,989,852 (GRCm39)	missense	unknown
R7241:Ahnak	UTSW	19	8,986,395 (GRCm39)	missense	possibly damaging	0.65
R7269:Ahnak	UTSW	19	8,983,981 (GRCm39)	missense	probably damaging	1.00
R7311:Ahnak	UTSW	19	8,979,507 (GRCm39)	missense	probably benign	0.04
R7311:Ahnak	UTSW	19	8,987,191 (GRCm39)	missense	possibly damaging	0.56
R7329:Ahnak	UTSW	19	8,979,156 (GRCm39)	missense	probably damaging	0.99
R7339:Ahnak	UTSW	19	8,985,529 (GRCm39)	missense	possibly damaging	0.75
R7390:Ahnak	UTSW	19	8,980,569 (GRCm39)	missense	probably benign	0.02
R7400:Ahnak	UTSW	19	8,991,977 (GRCm39)	missense	probably damaging	0.99
R7444:Ahnak	UTSW	19	8,984,787 (GRCm39)	missense	probably benign	0.08
R7483:Ahnak	UTSW	19	8,982,186 (GRCm39)	missense	probably damaging	1.00
R7498:Ahnak	UTSW	19	8,989,383 (GRCm39)	missense	probably benign	0.14
R7521:Ahnak	UTSW	19	8,979,715 (GRCm39)	missense	possibly damaging	0.89
R7522:Ahnak	UTSW	19	8,979,686 (GRCm39)	missense	probably benign	0.01
R7552:Ahnak	UTSW	19	8,984,188 (GRCm39)	missense	probably benign	0.18
R7563:Ahnak	UTSW	19	8,988,529 (GRCm39)	missense	probably damaging	0.99
R7565:Ahnak	UTSW	19	8,993,520 (GRCm39)	missense	probably benign	0.05
R7571:Ahnak	UTSW	19	8,978,150 (GRCm39)	nonsense	probably null
R7583:Ahnak	UTSW	19	8,983,457 (GRCm39)	missense	possibly damaging	0.90
R7600:Ahnak	UTSW	19	8,981,938 (GRCm39)	missense	possibly damaging	0.89
R7771:Ahnak	UTSW	19	8,992,411 (GRCm39)	missense	probably damaging	0.99
R7787:Ahnak	UTSW	19	8,986,679 (GRCm39)	missense	unknown
R7827:Ahnak	UTSW	19	8,982,708 (GRCm39)	nonsense	probably null
R7857:Ahnak	UTSW	19	8,984,832 (GRCm39)	missense	probably damaging	0.97
R7916:Ahnak	UTSW	19	8,983,196 (GRCm39)	missense	possibly damaging	0.66
R7939:Ahnak	UTSW	19	8,991,448 (GRCm39)	nonsense	probably null
R7959:Ahnak	UTSW	19	8,988,013 (GRCm39)	missense	possibly damaging	0.46
R7962:Ahnak	UTSW	19	8,990,164 (GRCm39)	missense	unknown
R7979:Ahnak	UTSW	19	8,988,796 (GRCm39)	missense	probably damaging	1.00
R8006:Ahnak	UTSW	19	8,989,447 (GRCm39)	missense	possibly damaging	0.79
R8013:Ahnak	UTSW	19	8,986,699 (GRCm39)	missense	unknown
R8033:Ahnak	UTSW	19	8,981,074 (GRCm39)	missense	probably benign	0.10
R8124:Ahnak	UTSW	19	8,984,487 (GRCm39)	missense	probably damaging	0.99
R8125:Ahnak	UTSW	19	8,989,240 (GRCm39)	missense	possibly damaging	0.95
R8129:Ahnak	UTSW	19	8,977,464 (GRCm39)	start codon destroyed	not run
R8151:Ahnak	UTSW	19	8,982,043 (GRCm39)	missense	possibly damaging	0.59
R8190:Ahnak	UTSW	19	8,979,619 (GRCm39)	missense	probably benign	0.01
R8221:Ahnak	UTSW	19	8,987,800 (GRCm39)	nonsense	probably null
R8241:Ahnak	UTSW	19	8,984,659 (GRCm39)	missense	probably benign	0.15
R8244:Ahnak	UTSW	19	8,993,037 (GRCm39)	missense	probably benign	0.44
R8248:Ahnak	UTSW	19	8,979,310 (GRCm39)	missense	probably damaging	1.00
R8261:Ahnak	UTSW	19	8,982,817 (GRCm39)	missense	probably damaging	1.00
R8330:Ahnak	UTSW	19	8,987,026 (GRCm39)	missense	possibly damaging	0.86
R8380:Ahnak	UTSW	19	8,995,219 (GRCm39)	missense	probably benign	0.05
R8407:Ahnak	UTSW	19	8,993,037 (GRCm39)	missense	probably benign	0.44
R8409:Ahnak	UTSW	19	8,993,037 (GRCm39)	missense	probably benign	0.44
R8463:Ahnak	UTSW	19	8,986,113 (GRCm39)	missense	probably benign	0.07
R8511:Ahnak	UTSW	19	8,989,719 (GRCm39)	missense	unknown
R8528:Ahnak	UTSW	19	8,985,092 (GRCm39)	missense	probably damaging	1.00
R8549:Ahnak	UTSW	19	8,988,847 (GRCm39)	missense	probably damaging	1.00
R8674:Ahnak	UTSW	19	8,983,360 (GRCm39)	missense	probably damaging	0.98
R8716:Ahnak	UTSW	19	8,986,438 (GRCm39)	missense	probably damaging	1.00
R8722:Ahnak	UTSW	19	8,990,710 (GRCm39)	nonsense	probably null
R8751:Ahnak	UTSW	19	8,987,509 (GRCm39)	missense	probably damaging	1.00
R8752:Ahnak	UTSW	19	8,992,901 (GRCm39)	missense	probably damaging	1.00
R8783:Ahnak	UTSW	19	8,988,837 (GRCm39)	missense	probably damaging	1.00
R8844:Ahnak	UTSW	19	8,984,254 (GRCm39)	missense	probably damaging	1.00
R8859:Ahnak	UTSW	19	8,984,567 (GRCm39)	missense	probably damaging	1.00
R8882:Ahnak	UTSW	19	8,978,106 (GRCm39)	missense	probably damaging	1.00
R8907:Ahnak	UTSW	19	8,986,452 (GRCm39)	missense	probably benign	0.24
R8938:Ahnak	UTSW	19	8,989,099 (GRCm39)	missense	probably benign	0.00
R8975:Ahnak	UTSW	19	8,990,101 (GRCm39)	missense	probably damaging	1.00
R8983:Ahnak	UTSW	19	8,981,477 (GRCm39)	missense	possibly damaging	0.75
R9017:Ahnak	UTSW	19	8,987,487 (GRCm39)	missense	probably damaging	1.00
R9027:Ahnak	UTSW	19	8,984,617 (GRCm39)	missense	possibly damaging	0.94
R9081:Ahnak	UTSW	19	8,985,890 (GRCm39)	missense	possibly damaging	0.81
R9104:Ahnak	UTSW	19	8,987,711 (GRCm39)	missense	probably benign	0.01
R9112:Ahnak	UTSW	19	8,987,149 (GRCm39)	missense	probably damaging	0.98
R9145:Ahnak	UTSW	19	8,992,287 (GRCm39)	missense	probably benign	0.38
R9189:Ahnak	UTSW	19	8,988,247 (GRCm39)	missense	possibly damaging	0.92
R9221:Ahnak	UTSW	19	8,989,943 (GRCm39)	missense	probably damaging	1.00
R9261:Ahnak	UTSW	19	8,993,503 (GRCm39)	missense	possibly damaging	0.63
R9299:Ahnak	UTSW	19	8,989,824 (GRCm39)	intron	probably benign
R9325:Ahnak	UTSW	19	8,991,257 (GRCm39)	missense	probably benign	0.12
R9337:Ahnak	UTSW	19	8,989,824 (GRCm39)	intron	probably benign
R9340:Ahnak	UTSW	19	8,994,411 (GRCm39)	missense	probably benign	0.04
R9351:Ahnak	UTSW	19	8,985,232 (GRCm39)	missense	probably damaging	1.00
R9416:Ahnak	UTSW	19	8,990,266 (GRCm39)	missense	unknown
R9462:Ahnak	UTSW	19	8,981,299 (GRCm39)	missense	probably damaging	0.96
R9469:Ahnak	UTSW	19	8,988,225 (GRCm39)	missense	probably damaging	1.00
R9485:Ahnak	UTSW	19	8,979,438 (GRCm39)	missense	probably benign	0.16
R9503:Ahnak	UTSW	19	8,987,458 (GRCm39)	missense	probably damaging	1.00
R9524:Ahnak	UTSW	19	9,014,617 (GRCm39)	missense
R9534:Ahnak	UTSW	19	8,980,976 (GRCm39)	missense	probably benign	0.20
R9598:Ahnak	UTSW	19	8,981,149 (GRCm39)	missense	probably benign	0.42
R9611:Ahnak	UTSW	19	8,989,162 (GRCm39)	missense	probably damaging	0.99
R9624:Ahnak	UTSW	19	8,989,846 (GRCm39)	missense	unknown
R9649:Ahnak	UTSW	19	8,985,786 (GRCm39)	nonsense	probably null
R9683:Ahnak	UTSW	19	8,984,719 (GRCm39)	missense	possibly damaging	0.94
R9712:Ahnak	UTSW	19	8,984,393 (GRCm39)	small deletion	probably benign
R9712:Ahnak	UTSW	19	8,984,392 (GRCm39)	small deletion	probably benign
R9713:Ahnak	UTSW	19	8,984,393 (GRCm39)	small deletion	probably benign
R9715:Ahnak	UTSW	19	8,984,393 (GRCm39)	small deletion	probably benign
R9725:Ahnak	UTSW	19	8,991,607 (GRCm39)	missense	probably damaging	1.00
R9725:Ahnak	UTSW	19	8,981,533 (GRCm39)	missense	probably benign	0.44
R9747:Ahnak	UTSW	19	8,987,541 (GRCm39)	missense	possibly damaging	0.49
R9798:Ahnak	UTSW	19	8,990,983 (GRCm39)	missense	probably damaging	0.99
RF007:Ahnak	UTSW	19	8,990,965 (GRCm39)	missense	possibly damaging	0.45
X0021:Ahnak	UTSW	19	8,990,983 (GRCm39)	missense	probably damaging	0.99
X0027:Ahnak	UTSW	19	8,989,401 (GRCm39)	missense	probably damaging	1.00
Z1088:Ahnak	UTSW	19	8,993,446 (GRCm39)	missense	probably damaging	0.99
Z1176:Ahnak	UTSW	19	8,986,220 (GRCm39)	missense	probably damaging	0.97
Z1177:Ahnak	UTSW	19	8,994,832 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GCTCCAAAGATCTCCATGCC -3'
(R):5'- ATGTCAGGCATGGAGATCTTGG -3'

Sequencing Primer
(F):5'- CCAAAGATCTCCATGCCTGATATTG -3'
(R):5'- CATCTCAGGCATCTTGAACTTGGG -3'

Posted On

2022-10-06