Incidental Mutation 'R9695:Adgrl1'
| ID |
729220 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adgrl1
|
| Ensembl Gene |
ENSMUSG00000013033 |
| Gene Name |
adhesion G protein-coupled receptor L1 |
| Synonyms |
Lec2, 2900070I05Rik, lectomedin-2, Lphn1 |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9695 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
8 |
| Chromosomal Location |
84626734-84668583 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 84665060 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Glutamine
at position 1249
(R1249Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000118452
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000045393]
[ENSMUST00000098595]
[ENSMUST00000124355]
[ENSMUST00000131717]
[ENSMUST00000132500]
[ENSMUST00000141158]
[ENSMUST00000152978]
|
| AlphaFold |
Q80TR1 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000045393
AA Change: R1254Q
PolyPhen 2
Score 0.987 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000048422
Gene: ENSMUSG00000013033
AA Change: R1254Q
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Pfam:Gal_Lectin
|
48 |
128 |
6.6e-23 |
PFAM |
|
OLF
|
142 |
398 |
8.5e-138 |
SMART |
|
low complexity region
|
405 |
441 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
470 |
N/A |
INTRINSIC |
|
HormR
|
476 |
541 |
1.4e-23 |
SMART |
|
low complexity region
|
579 |
591 |
N/A |
INTRINSIC |
|
low complexity region
|
747 |
758 |
N/A |
INTRINSIC |
|
GPS
|
797 |
849 |
3.5e-27 |
SMART |
|
Pfam:7tm_2
|
856 |
1092 |
5.3e-66 |
PFAM |
|
Pfam:Latrophilin
|
1112 |
1470 |
1.7e-177 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000098595
|
| SMART Domains |
Protein: ENSMUSP00000096195
Gene: ENSMUSG00000074219
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
60 |
72 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000124355
|
| SMART Domains |
Protein: ENSMUSP00000116064
Gene: ENSMUSG00000013033
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Pfam:Gal_Lectin
|
48 |
128 |
1.1e-24 |
PFAM |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000117720
Gene: ENSMUSG00000013033
AA Change: R68Q
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Latrophilin
|
1 |
213 |
9.2e-76 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000131717
AA Change: R1078Q
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000118579
Gene: ENSMUSG00000013033
AA Change: R1078Q
| Domain | Start | End | E-Value | Type |
|---|
|
OLF
|
1 |
222 |
4.51e-103 |
SMART |
|
low complexity region
|
229 |
265 |
N/A |
INTRINSIC |
|
low complexity region
|
279 |
294 |
N/A |
INTRINSIC |
|
HormR
|
300 |
365 |
2.26e-21 |
SMART |
|
low complexity region
|
403 |
415 |
N/A |
INTRINSIC |
|
low complexity region
|
571 |
582 |
N/A |
INTRINSIC |
|
GPS
|
621 |
673 |
5.64e-25 |
SMART |
|
Pfam:7tm_2
|
680 |
916 |
7.9e-68 |
PFAM |
|
Pfam:Latrophilin
|
936 |
1295 |
2.7e-181 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000132500
AA Change: R1294Q
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000119100
Gene: ENSMUSG00000013033
AA Change: R1294Q
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
Pfam:Gal_Lectin
|
48 |
128 |
1.6e-25 |
PFAM |
|
OLF
|
137 |
393 |
1.39e-135 |
SMART |
|
low complexity region
|
400 |
436 |
N/A |
INTRINSIC |
|
low complexity region
|
450 |
465 |
N/A |
INTRINSIC |
|
HormR
|
471 |
536 |
2.26e-21 |
SMART |
|
low complexity region
|
574 |
586 |
N/A |
INTRINSIC |
|
low complexity region
|
742 |
753 |
N/A |
INTRINSIC |
|
GPS
|
792 |
844 |
5.64e-25 |
SMART |
|
Pfam:7tm_2
|
851 |
1087 |
3.4e-68 |
PFAM |
|
Pfam:Latrophilin
|
1146 |
1511 |
6.4e-193 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000141158
AA Change: R1249Q
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000118452
Gene: ENSMUSG00000013033
AA Change: R1249Q
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
Pfam:Gal_Lectin
|
48 |
128 |
3.4e-25 |
PFAM |
|
OLF
|
137 |
393 |
1.39e-135 |
SMART |
|
low complexity region
|
400 |
436 |
N/A |
INTRINSIC |
|
low complexity region
|
450 |
465 |
N/A |
INTRINSIC |
|
HormR
|
471 |
536 |
2.26e-21 |
SMART |
|
low complexity region
|
574 |
586 |
N/A |
INTRINSIC |
|
low complexity region
|
742 |
753 |
N/A |
INTRINSIC |
|
GPS
|
792 |
844 |
5.64e-25 |
SMART |
|
Pfam:7tm_2
|
851 |
1087 |
4.5e-68 |
PFAM |
|
Pfam:Latrophilin
|
1107 |
1466 |
1.1e-180 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000152978
AA Change: R1299Q
PolyPhen 2
Score 0.955 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000115295
Gene: ENSMUSG00000013033
AA Change: R1299Q
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
Pfam:Gal_Lectin
|
48 |
128 |
2.1e-25 |
PFAM |
|
OLF
|
142 |
398 |
1.39e-135 |
SMART |
|
low complexity region
|
405 |
441 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
470 |
N/A |
INTRINSIC |
|
HormR
|
476 |
541 |
2.26e-21 |
SMART |
|
Pfam:GAIN
|
544 |
773 |
4.1e-59 |
PFAM |
|
GPS
|
797 |
849 |
5.64e-25 |
SMART |
|
Pfam:7tm_2
|
856 |
1092 |
2.3e-69 |
PFAM |
|
Pfam:Latrophilin
|
1112 |
1516 |
7.3e-136 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]
PHENOTYPE: Mice homozygous for a targeted null allele at this locus are viable and fertile. Female homozygotes fail adequately to care for their litters. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 66 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ablim1 |
T |
C |
19: 57,170,739 (GRCm39) |
T1A |
|
Het |
| Apeh |
G |
A |
9: 107,963,483 (GRCm39) |
R580C |
probably damaging |
Het |
| Armc12 |
T |
A |
17: 28,749,993 (GRCm39) |
C46S |
probably benign |
Het |
| Avpr1a |
C |
T |
10: 122,284,845 (GRCm39) |
R46C |
probably damaging |
Het |
| Cbln4 |
C |
G |
2: 171,879,469 (GRCm39) |
G140R |
probably damaging |
Het |
| Ccdc89 |
A |
G |
7: 90,076,552 (GRCm39) |
N254S |
probably benign |
Het |
| Cd96 |
T |
A |
16: 45,919,410 (GRCm39) |
I204F |
probably damaging |
Het |
| Cel |
G |
T |
2: 28,450,961 (GRCm39) |
L101I |
probably damaging |
Het |
| Crtap |
A |
T |
9: 114,215,378 (GRCm39) |
Y170* |
probably null |
Het |
| Ctxn3 |
A |
G |
18: 57,610,185 (GRCm39) |
M1V |
probably null |
Het |
| Cwf19l1 |
G |
T |
19: 44,101,425 (GRCm39) |
H478N |
probably damaging |
Het |
| Dpysl3 |
A |
T |
18: 43,571,192 (GRCm39) |
D27E |
probably damaging |
Het |
| Dsg1b |
A |
G |
18: 20,532,389 (GRCm39) |
T478A |
probably damaging |
Het |
| Dvl2 |
G |
A |
11: 69,899,976 (GRCm39) |
R590Q |
possibly damaging |
Het |
| Elovl7 |
C |
A |
13: 108,416,242 (GRCm39) |
Q211K |
probably damaging |
Het |
| Fech |
A |
G |
18: 64,600,803 (GRCm39) |
I233T |
probably damaging |
Het |
| Fsip2 |
A |
T |
2: 82,806,226 (GRCm39) |
Q848H |
probably benign |
Het |
| Gna15 |
A |
G |
10: 81,359,752 (GRCm39) |
C13R |
probably damaging |
Het |
| Gstt4 |
A |
T |
10: 75,657,072 (GRCm39) |
S65T |
probably benign |
Het |
| Heatr1 |
T |
C |
13: 12,438,624 (GRCm39) |
V1353A |
probably damaging |
Het |
| Hip1r |
A |
T |
5: 124,139,916 (GRCm39) |
K1006N |
possibly damaging |
Het |
| Hspg2 |
T |
A |
4: 137,265,701 (GRCm39) |
V1804E |
probably damaging |
Het |
| Ifi206 |
T |
C |
1: 173,301,249 (GRCm39) |
T810A |
unknown |
Het |
| Ighv1-69 |
T |
C |
12: 115,586,987 (GRCm39) |
T49A |
probably benign |
Het |
| Il4i1 |
A |
T |
7: 44,489,033 (GRCm39) |
D266V |
probably damaging |
Het |
| Itga3 |
A |
T |
11: 94,946,520 (GRCm39) |
|
probably null |
Het |
| Itpr1 |
A |
G |
6: 108,378,311 (GRCm39) |
N1279S |
probably damaging |
Het |
| Madd |
T |
C |
2: 90,992,929 (GRCm39) |
T997A |
probably benign |
Het |
| Mal |
C |
T |
2: 127,482,308 (GRCm39) |
V32I |
probably benign |
Het |
| Map9 |
T |
A |
3: 82,284,292 (GRCm39) |
S289T |
probably benign |
Het |
| Mmp15 |
G |
T |
8: 96,097,414 (GRCm39) |
R461L |
possibly damaging |
Het |
| Nelfcd |
T |
A |
2: 174,266,923 (GRCm39) |
I395N |
probably benign |
Het |
| Neurog2 |
T |
A |
3: 127,427,694 (GRCm39) |
V106E |
probably damaging |
Het |
| Nup160 |
T |
A |
2: 90,538,486 (GRCm39) |
N761K |
probably damaging |
Het |
| Oasl1 |
G |
A |
5: 115,074,054 (GRCm39) |
R321Q |
probably damaging |
Het |
| Oosp2 |
T |
C |
19: 11,628,994 (GRCm39) |
T36A |
|
Het |
| Or2a52 |
A |
T |
6: 43,144,510 (GRCm39) |
I173L |
probably benign |
Het |
| Or7g22 |
A |
G |
9: 19,049,171 (GRCm39) |
N294S |
probably damaging |
Het |
| Or8k30 |
T |
C |
2: 86,339,100 (GRCm39) |
V99A |
probably benign |
Het |
| Or9s27 |
A |
G |
1: 92,516,595 (GRCm39) |
D181G |
probably benign |
Het |
| Otx2 |
T |
G |
14: 48,899,952 (GRCm39) |
S16R |
probably damaging |
Het |
| Phactr2 |
A |
G |
10: 13,349,908 (GRCm39) |
S39P |
unknown |
Het |
| Piwil2 |
A |
G |
14: 70,627,349 (GRCm39) |
Y797H |
possibly damaging |
Het |
| Plxna4 |
T |
G |
6: 32,183,056 (GRCm39) |
Y949S |
probably benign |
Het |
| Prss35 |
A |
G |
9: 86,637,761 (GRCm39) |
Y177C |
probably damaging |
Het |
| Rbm19 |
T |
C |
5: 120,335,986 (GRCm39) |
I934T |
probably damaging |
Het |
| Rictor |
T |
G |
15: 6,816,010 (GRCm39) |
V1094G |
probably benign |
Het |
| Riok1 |
A |
G |
13: 38,242,676 (GRCm39) |
T467A |
possibly damaging |
Het |
| Slc15a4 |
G |
A |
5: 127,694,400 (GRCm39) |
R12W |
possibly damaging |
Het |
| Slc44a5 |
T |
A |
3: 153,956,588 (GRCm39) |
I280K |
probably damaging |
Het |
| Slc9c1 |
T |
C |
16: 45,368,026 (GRCm39) |
L205S |
probably benign |
Het |
| Slco2a1 |
A |
G |
9: 102,962,139 (GRCm39) |
R604G |
possibly damaging |
Het |
| Slmap |
T |
A |
14: 26,183,496 (GRCm39) |
T296S |
probably damaging |
Het |
| Snrk |
T |
C |
9: 121,995,640 (GRCm39) |
V473A |
probably benign |
Het |
| Spart |
A |
G |
3: 55,033,955 (GRCm39) |
T394A |
probably benign |
Het |
| Stil |
T |
C |
4: 114,881,378 (GRCm39) |
S641P |
probably damaging |
Het |
| Syne1 |
A |
G |
10: 5,268,461 (GRCm39) |
V2076A |
probably benign |
Het |
| Tcirg1 |
G |
A |
19: 3,952,360 (GRCm39) |
A336V |
probably null |
Het |
| Tespa1 |
T |
C |
10: 130,198,285 (GRCm39) |
S436P |
probably benign |
Het |
| Thumpd3 |
G |
T |
6: 113,024,622 (GRCm39) |
R72L |
possibly damaging |
Het |
| Tmem70 |
A |
C |
1: 16,735,659 (GRCm39) |
E43A |
probably benign |
Het |
| Vars1 |
A |
G |
17: 35,231,564 (GRCm39) |
D696G |
possibly damaging |
Het |
| Vwa5b2 |
A |
T |
16: 20,422,975 (GRCm39) |
H991L |
probably benign |
Het |
| Zfp160 |
A |
G |
17: 21,245,746 (GRCm39) |
K99E |
possibly damaging |
Het |
| Zfp759 |
G |
A |
13: 67,287,198 (GRCm39) |
V250I |
possibly damaging |
Het |
| Zmym6 |
T |
C |
4: 127,016,340 (GRCm39) |
V707A |
probably benign |
Het |
|
| Other mutations in Adgrl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00965:Adgrl1
|
APN |
8 |
84,664,332 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01413:Adgrl1
|
APN |
8 |
84,656,486 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02020:Adgrl1
|
APN |
8 |
84,659,577 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02422:Adgrl1
|
APN |
8 |
84,664,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03065:Adgrl1
|
APN |
8 |
84,665,143 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03169:Adgrl1
|
APN |
8 |
84,658,624 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03237:Adgrl1
|
APN |
8 |
84,656,312 (GRCm39) |
splice site |
probably null |
|
|
Swiss_rolls
|
UTSW |
8 |
84,645,551 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0375:Adgrl1
|
UTSW |
8 |
84,661,530 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0505:Adgrl1
|
UTSW |
8 |
84,661,279 (GRCm39) |
splice site |
probably benign |
|
|
R0681:Adgrl1
|
UTSW |
8 |
84,661,279 (GRCm39) |
splice site |
probably benign |
|
|
R0964:Adgrl1
|
UTSW |
8 |
84,661,041 (GRCm39) |
splice site |
probably benign |
|
|
R1182:Adgrl1
|
UTSW |
8 |
84,656,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1373:Adgrl1
|
UTSW |
8 |
84,664,392 (GRCm39) |
missense |
probably benign |
0.23 |
|
R1475:Adgrl1
|
UTSW |
8 |
84,664,979 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R1610:Adgrl1
|
UTSW |
8 |
84,659,002 (GRCm39) |
missense |
probably benign |
0.16 |
|
R1778:Adgrl1
|
UTSW |
8 |
84,656,666 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2089:Adgrl1
|
UTSW |
8 |
84,661,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2091:Adgrl1
|
UTSW |
8 |
84,661,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2091:Adgrl1
|
UTSW |
8 |
84,661,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2300:Adgrl1
|
UTSW |
8 |
84,656,746 (GRCm39) |
nonsense |
probably null |
|
|
R2403:Adgrl1
|
UTSW |
8 |
84,657,870 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2935:Adgrl1
|
UTSW |
8 |
84,661,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3772:Adgrl1
|
UTSW |
8 |
84,649,633 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R4191:Adgrl1
|
UTSW |
8 |
84,665,569 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4393:Adgrl1
|
UTSW |
8 |
84,665,222 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4406:Adgrl1
|
UTSW |
8 |
84,656,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4445:Adgrl1
|
UTSW |
8 |
84,661,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4782:Adgrl1
|
UTSW |
8 |
84,662,202 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4799:Adgrl1
|
UTSW |
8 |
84,662,202 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5214:Adgrl1
|
UTSW |
8 |
84,642,202 (GRCm39) |
splice site |
probably null |
|
|
R5242:Adgrl1
|
UTSW |
8 |
84,657,711 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R5409:Adgrl1
|
UTSW |
8 |
84,656,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5522:Adgrl1
|
UTSW |
8 |
84,649,704 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5607:Adgrl1
|
UTSW |
8 |
84,663,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5608:Adgrl1
|
UTSW |
8 |
84,663,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5652:Adgrl1
|
UTSW |
8 |
84,656,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5655:Adgrl1
|
UTSW |
8 |
84,665,230 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5919:Adgrl1
|
UTSW |
8 |
84,659,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6033:Adgrl1
|
UTSW |
8 |
84,645,551 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6033:Adgrl1
|
UTSW |
8 |
84,645,551 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6129:Adgrl1
|
UTSW |
8 |
84,645,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6221:Adgrl1
|
UTSW |
8 |
84,664,316 (GRCm39) |
nonsense |
probably null |
|
|
R7142:Adgrl1
|
UTSW |
8 |
84,663,829 (GRCm39) |
missense |
probably benign |
0.38 |
|
R7181:Adgrl1
|
UTSW |
8 |
84,652,878 (GRCm39) |
splice site |
probably null |
|
|
R7238:Adgrl1
|
UTSW |
8 |
84,665,693 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7547:Adgrl1
|
UTSW |
8 |
84,665,513 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7709:Adgrl1
|
UTSW |
8 |
84,665,617 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7741:Adgrl1
|
UTSW |
8 |
84,656,343 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7852:Adgrl1
|
UTSW |
8 |
84,662,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7866:Adgrl1
|
UTSW |
8 |
84,664,564 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8146:Adgrl1
|
UTSW |
8 |
84,657,618 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R8314:Adgrl1
|
UTSW |
8 |
84,665,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8829:Adgrl1
|
UTSW |
8 |
84,665,458 (GRCm39) |
missense |
|
|
|
R8857:Adgrl1
|
UTSW |
8 |
84,657,657 (GRCm39) |
missense |
probably benign |
0.24 |
|
R8979:Adgrl1
|
UTSW |
8 |
84,665,015 (GRCm39) |
missense |
probably benign |
0.12 |
|
R9204:Adgrl1
|
UTSW |
8 |
84,660,519 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9226:Adgrl1
|
UTSW |
8 |
84,656,426 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9302:Adgrl1
|
UTSW |
8 |
84,656,426 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9785:Adgrl1
|
UTSW |
8 |
84,665,168 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF007:Adgrl1
|
UTSW |
8 |
84,661,401 (GRCm39) |
missense |
probably benign |
0.14 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACACCCCTGTCAGCCTATTG -3'
(R):5'- AGTTCAATCTCTGCCCGGTC -3'
Sequencing Primer
(F):5'- AGACGCCACTGCAGCAGAG -3'
(R):5'- AATCTCTGCCCGGTCAGCAC -3'
|
| Posted On |
2022-10-06 |
Incidental Mutation