Mutagenetix > Incidental Mutation

Incidental Mutation 'R9696:Vps13b'

729322

Institutional Source

Beutler Lab

Gene Symbol

Vps13b

Ensembl Gene

ENSMUSG00000037646

Gene Name

vacuolar protein sorting 13B

Synonyms

1810042B05Rik, C330002D13Rik, 2310042E16Rik, Coh1

MMRRC Submission

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R9696 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

35371306-35931375 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to A at 35675033 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glutamine to Lysine at position 1718 (Q1718K)

Ref Sequence

ENSEMBL: ENSMUSP00000045490 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000048646]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000048646
AA Change: Q1718K

PolyPhen 2 Score 0.563 (Sensitivity: 0.88; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000045490
Gene: ENSMUSG00000037646
AA Change: Q1718K

Domain	Start	End	E-Value	Type
Pfam:Chorein_N	2	120	1e-29	PFAM
low complexity region	128	137	N/A	INTRINSIC
low complexity region	143	160	N/A	INTRINSIC
low complexity region	975	984	N/A	INTRINSIC
low complexity region	1007	1018	N/A	INTRINSIC
low complexity region	1876	1883	N/A	INTRINSIC
low complexity region	2042	2054	N/A	INTRINSIC
low complexity region	2414	2423	N/A	INTRINSIC
Pfam:SHR-BD	2601	2700	8.4e-10	PFAM
low complexity region	2954	2964	N/A	INTRINSIC
Pfam:VPS13_C	3539	3706	2.6e-30	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 99.0%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a potential transmembrane protein that may function in vesicle-mediated transport and sorting of proteins within the cell. This protein may play a role in the development and the function of the eye, hematological system, and central nervous system. Mutations in this gene have been associated with Cohen syndrome. Multiple splice variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 82 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700001O22Rik	T	C	2: 30,691,256 (GRCm39)	D105G	possibly damaging	Het
4930407I10Rik	A	G	15: 81,949,697 (GRCm39)	N1198S	probably benign	Het
Abca14	A	T	7: 119,888,734 (GRCm39)	I1227F	possibly damaging	Het
Abhd10	T	C	16: 45,552,042 (GRCm39)	D277G	probably damaging	Het
Adam20	A	G	8: 41,249,633 (GRCm39)	N581S	probably damaging	Het
Apbb1ip	A	T	2: 22,725,989 (GRCm39)	T254S	probably benign	Het
Arap3	T	C	18: 38,112,905 (GRCm39)	T1102A	probably damaging	Het
Asb16	A	T	11: 102,159,766 (GRCm39)	R40W	probably damaging	Het
Birc6	T	A	17: 74,947,292 (GRCm39)	S3019T	probably damaging	Het
Btbd18	T	A	2: 84,497,854 (GRCm39)	C497*	probably null	Het
Cacna1h	T	C	17: 25,602,215 (GRCm39)	M1542V	possibly damaging	Het
Ccdc8	T	G	7: 16,730,087 (GRCm39)	S525R	unknown	Het
Ch25h	G	A	19: 34,451,947 (GRCm39)	R194W	probably damaging	Het
Ciapin1	C	A	8: 95,555,065 (GRCm39)	L130F	probably damaging	Het
Cnfn	G	T	7: 25,067,515 (GRCm39)	T54N	probably damaging	Het
Cop1	A	T	1: 159,076,783 (GRCm39)	I195F	probably damaging	Het
Daam1	A	G	12: 71,991,147 (GRCm39)	R254G	unknown	Het
Dcaf13	T	C	15: 39,001,496 (GRCm39)	M268T	possibly damaging	Het
Disp3	C	A	4: 148,345,611 (GRCm39)	V410L	probably damaging	Het
Dus4l	A	T	12: 31,696,647 (GRCm39)	I110K	probably damaging	Het
Endov	C	T	11: 119,398,048 (GRCm39)	P271L	probably damaging	Het
Epha2	A	G	4: 141,047,834 (GRCm39)	I539V	probably benign	Het
Ercc4	A	T	16: 12,950,810 (GRCm39)	I635L	probably damaging	Het
Exosc10	A	G	4: 148,649,704 (GRCm39)	D378G	probably damaging	Het
Fmnl1	A	G	11: 103,086,297 (GRCm39)	D804G	unknown	Het
Gm11983	T	A	11: 6,787,020 (GRCm39)	I36F	unknown	Het
Gm11992	A	T	11: 9,006,438 (GRCm39)	I123L	probably benign	Het
Gm19965	T	C	1: 116,730,838 (GRCm39)		probably benign	Het
Gm19965	A	G	1: 116,749,210 (GRCm39)	D297G		Het
Gpr180	G	A	14: 118,391,302 (GRCm39)	G235R	probably damaging	Het
Gse1	T	C	8: 120,956,280 (GRCm39)	V257A	unknown	Het
Haus1	A	T	18: 77,847,202 (GRCm39)	S225T	probably benign	Het
Hgf	A	G	5: 16,777,534 (GRCm39)	Y177C	probably damaging	Het
Insig1	T	C	5: 28,279,546 (GRCm39)	W184R	probably damaging	Het
Krt5	A	T	15: 101,616,141 (GRCm39)	S491R	unknown	Het
Lcn5	A	G	2: 25,550,142 (GRCm39)	I110V	probably benign	Het
Lin9	A	T	1: 180,496,733 (GRCm39)	S341C	possibly damaging	Het
Magi2	C	T	5: 20,670,864 (GRCm39)	H403Y	probably benign	Het
Mapk1ip1l	C	T	14: 47,548,340 (GRCm39)	P163S	probably damaging	Het
Mbtd1	A	G	11: 93,823,218 (GRCm39)	D568G	probably damaging	Het
Mdp1	A	G	14: 55,896,704 (GRCm39)	V119A	probably benign	Het
Me1	A	G	9: 86,469,047 (GRCm39)	I506T	probably damaging	Het
Med1	A	G	11: 98,061,772 (GRCm39)		probably null	Het
Med25	T	A	7: 44,529,524 (GRCm39)	Q656L	probably benign	Het
Memo1	A	C	17: 74,524,041 (GRCm39)	I213S	probably damaging	Het
Mfsd14b	C	A	13: 65,221,414 (GRCm39)	V293L	probably benign	Het
Mpi	T	C	9: 57,452,539 (GRCm39)	D331G	probably benign	Het
Muc4	T	C	16: 32,574,712 (GRCm39)	I1054T	probably benign	Het
Nat10	T	C	2: 103,556,040 (GRCm39)	E927G	possibly damaging	Het
Nlrp9a	T	C	7: 26,275,033 (GRCm39)	L930P	unknown	Het
Nt5c3b	A	T	11: 100,323,811 (GRCm39)	I167N	probably damaging	Het
Ogdh	T	C	11: 6,289,209 (GRCm39)	S308P	probably damaging	Het
Or2y1b	A	G	11: 49,208,390 (GRCm39)	I6V	probably benign	Het
Or4c108	T	G	2: 88,803,615 (GRCm39)	I207L	probably benign	Het
Or52e5	T	A	7: 104,719,283 (GRCm39)	V203D	probably damaging	Het
Or8b9	G	A	9: 37,766,671 (GRCm39)	E186K	probably benign	Het
Parl	A	G	16: 20,105,690 (GRCm39)	V244A	probably benign	Het
Parp14	G	T	16: 35,661,252 (GRCm39)	D1565E	probably damaging	Het
Parp14	T	C	16: 35,661,251 (GRCm39)	K1566E	possibly damaging	Het
Pcdhb18	T	A	18: 37,623,606 (GRCm39)	I312K	possibly damaging	Het
Pcnp	A	T	16: 55,844,867 (GRCm39)		probably benign	Het
Peg10	CATCAGGATCCCCATCAGGATGCACATCAGGATCCACATCAGGATGCACATCAGGATC	CATC	6: 4,756,431 (GRCm39)		probably benign	Het
Rab10	T	A	12: 3,306,947 (GRCm39)	M83L	probably benign	Het
Rabep1	A	G	11: 70,814,029 (GRCm39)	S616G	probably benign	Het
Rnf213	G	A	11: 119,359,806 (GRCm39)	V4400M		Het
Samd9l	T	A	6: 3,375,078 (GRCm39)	I728F	possibly damaging	Het
Scaf4	T	A	16: 90,044,122 (GRCm39)	D620V	unknown	Het
Scnn1b	A	T	7: 121,498,462 (GRCm39)	M1L	probably damaging	Het
Sec23b	T	A	2: 144,428,343 (GRCm39)	M652K	probably benign	Het
Selenoi	T	C	5: 30,453,413 (GRCm39)	F44L	probably benign	Het
Slc36a3	A	T	11: 55,026,161 (GRCm39)	V219E	possibly damaging	Het
Sncaip	A	T	18: 53,038,915 (GRCm39)	Q543L	probably damaging	Het
Stmnd1	A	G	13: 46,443,224 (GRCm39)	I119V	probably damaging	Het
Strn3	T	A	12: 51,676,286 (GRCm39)	E414D	probably damaging	Het
Syne1	T	A	10: 5,297,847 (GRCm39)	H1150L	probably benign	Het
Tdrd7	A	G	4: 46,016,888 (GRCm39)	N676S	possibly damaging	Het
Tgs1	A	T	4: 3,575,071 (GRCm39)	I16F	possibly damaging	Het
Thnsl2	T	G	6: 71,108,930 (GRCm39)	T294P	possibly damaging	Het
Tmem156	A	G	5: 65,231,147 (GRCm39)	I241T	possibly damaging	Het
Unc13a	A	T	8: 72,082,197 (GRCm39)	M1689K	possibly damaging	Het
Uri1	T	C	7: 37,664,738 (GRCm39)	D318G	probably benign	Het
Vmn2r86	T	A	10: 130,285,702 (GRCm39)	Q491L	possibly damaging	Het

Other mutations in Vps13b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00402:Vps13b	APN	15	35,926,372 (GRCm39)	missense	possibly damaging	0.52
IGL00513:Vps13b	APN	15	35,794,030 (GRCm39)	missense	probably damaging	1.00
IGL00516:Vps13b	APN	15	35,640,703 (GRCm39)	missense	probably damaging	1.00
IGL00640:Vps13b	APN	15	35,417,723 (GRCm39)	missense	probably benign
IGL00753:Vps13b	APN	15	35,372,177 (GRCm39)	missense	probably damaging	0.99
IGL00784:Vps13b	APN	15	35,847,046 (GRCm39)	missense	probably damaging	1.00
IGL01138:Vps13b	APN	15	35,446,916 (GRCm39)	splice site	probably benign
IGL01349:Vps13b	APN	15	35,794,091 (GRCm39)	missense	probably benign	0.00
IGL01403:Vps13b	APN	15	35,709,625 (GRCm39)	missense	probably benign	0.00
IGL01535:Vps13b	APN	15	35,455,103 (GRCm39)	missense	possibly damaging	0.67
IGL01571:Vps13b	APN	15	35,877,635 (GRCm39)	splice site	probably benign
IGL01642:Vps13b	APN	15	35,792,218 (GRCm39)	missense	probably benign	0.43
IGL01658:Vps13b	APN	15	35,671,479 (GRCm39)	missense	probably damaging	0.99
IGL01759:Vps13b	APN	15	35,878,935 (GRCm39)	missense	probably damaging	1.00
IGL01763:Vps13b	APN	15	35,709,945 (GRCm39)	missense	possibly damaging	0.72
IGL01906:Vps13b	APN	15	35,639,993 (GRCm39)	splice site	probably benign
IGL01982:Vps13b	APN	15	35,439,050 (GRCm39)	nonsense	probably null
IGL01997:Vps13b	APN	15	35,709,370 (GRCm39)	missense	probably damaging	1.00
IGL02041:Vps13b	APN	15	35,423,391 (GRCm39)	missense	probably damaging	0.98
IGL02073:Vps13b	APN	15	35,875,732 (GRCm39)	missense	possibly damaging	0.52
IGL02077:Vps13b	APN	15	35,910,759 (GRCm39)	missense	possibly damaging	0.68
IGL02141:Vps13b	APN	15	35,572,227 (GRCm39)	missense	probably benign	0.09
IGL02146:Vps13b	APN	15	35,646,479 (GRCm39)	missense	probably benign	0.36
IGL02197:Vps13b	APN	15	35,930,202 (GRCm39)	missense	probably benign	0.02
IGL02311:Vps13b	APN	15	35,709,660 (GRCm39)	missense	probably benign	0.08
IGL02466:Vps13b	APN	15	35,770,887 (GRCm39)	missense	possibly damaging	0.86
IGL02506:Vps13b	APN	15	35,917,308 (GRCm39)	missense	probably damaging	1.00
IGL02550:Vps13b	APN	15	35,572,242 (GRCm39)	missense	probably benign
IGL02553:Vps13b	APN	15	35,646,447 (GRCm39)	missense	probably benign	0.00
IGL02674:Vps13b	APN	15	35,640,104 (GRCm39)	missense	probably benign	0.41
IGL02690:Vps13b	APN	15	35,917,288 (GRCm39)	missense	probably damaging	1.00
IGL02731:Vps13b	APN	15	35,917,274 (GRCm39)	missense	probably benign	0.00
IGL02739:Vps13b	APN	15	35,880,046 (GRCm39)	missense	probably damaging	1.00
IGL02868:Vps13b	APN	15	35,884,665 (GRCm39)	missense	probably benign	0.03
IGL03081:Vps13b	APN	15	35,875,966 (GRCm39)	missense	probably damaging	0.97
IGL03178:Vps13b	APN	15	35,869,446 (GRCm39)	missense	probably damaging	1.00
IGL03343:Vps13b	APN	15	35,917,316 (GRCm39)	missense	possibly damaging	0.76
IGL03407:Vps13b	APN	15	35,640,012 (GRCm39)	missense	possibly damaging	0.95
IGL03410:Vps13b	APN	15	35,910,486 (GRCm39)	missense	probably benign
omlette	UTSW	15	35,671,546 (GRCm39)	missense	probably benign	0.13
swiss	UTSW	15	35,709,819 (GRCm39)	missense	possibly damaging	0.80
FR4449:Vps13b	UTSW	15	35,847,103 (GRCm39)	missense	probably damaging	1.00
FR4548:Vps13b	UTSW	15	35,847,103 (GRCm39)	missense	probably damaging	1.00
FR4737:Vps13b	UTSW	15	35,847,103 (GRCm39)	missense	probably damaging	1.00
FR4976:Vps13b	UTSW	15	35,847,103 (GRCm39)	missense	probably damaging	1.00
LCD18:Vps13b	UTSW	15	35,847,103 (GRCm39)	missense	probably damaging	1.00
PIT4531001:Vps13b	UTSW	15	35,878,971 (GRCm39)	missense	probably damaging	1.00
PIT4581001:Vps13b	UTSW	15	35,534,409 (GRCm39)	missense	probably damaging	1.00
PIT4618001:Vps13b	UTSW	15	35,709,386 (GRCm39)	missense	probably damaging	1.00
R0026:Vps13b	UTSW	15	35,923,447 (GRCm39)	missense	possibly damaging	0.62
R0026:Vps13b	UTSW	15	35,923,447 (GRCm39)	missense	possibly damaging	0.62
R0108:Vps13b	UTSW	15	35,572,265 (GRCm39)	missense	probably benign	0.20
R0109:Vps13b	UTSW	15	35,572,265 (GRCm39)	missense	probably benign	0.20
R0109:Vps13b	UTSW	15	35,572,265 (GRCm39)	missense	probably benign	0.20
R0116:Vps13b	UTSW	15	35,423,301 (GRCm39)	missense	probably damaging	0.99
R0123:Vps13b	UTSW	15	35,887,407 (GRCm39)	missense	probably benign	0.01
R0124:Vps13b	UTSW	15	35,576,674 (GRCm39)	critical splice donor site	probably null
R0134:Vps13b	UTSW	15	35,887,407 (GRCm39)	missense	probably benign	0.01
R0137:Vps13b	UTSW	15	35,926,365 (GRCm39)	missense	probably benign	0.06
R0195:Vps13b	UTSW	15	35,472,045 (GRCm39)	missense	probably benign	0.00
R0225:Vps13b	UTSW	15	35,887,407 (GRCm39)	missense	probably benign	0.01
R0320:Vps13b	UTSW	15	35,674,974 (GRCm39)	missense	probably damaging	0.98
R0333:Vps13b	UTSW	15	35,879,949 (GRCm39)	missense	probably damaging	1.00
R0336:Vps13b	UTSW	15	35,455,279 (GRCm39)	nonsense	probably null
R0463:Vps13b	UTSW	15	35,597,555 (GRCm39)	missense	probably damaging	0.98
R0466:Vps13b	UTSW	15	35,445,748 (GRCm39)	nonsense	probably null
R0472:Vps13b	UTSW	15	35,417,779 (GRCm39)	critical splice donor site	probably null
R0523:Vps13b	UTSW	15	35,472,196 (GRCm39)	missense	probably benign	0.20
R0602:Vps13b	UTSW	15	35,422,514 (GRCm39)	missense	probably damaging	1.00
R0612:Vps13b	UTSW	15	35,623,803 (GRCm39)	missense	probably benign	0.12
R0627:Vps13b	UTSW	15	35,372,145 (GRCm39)	nonsense	probably null
R0679:Vps13b	UTSW	15	35,709,849 (GRCm39)	missense	possibly damaging	0.73
R0742:Vps13b	UTSW	15	35,794,507 (GRCm39)	missense	probably benign	0.22
R1053:Vps13b	UTSW	15	35,652,509 (GRCm39)	missense	probably damaging	1.00
R1355:Vps13b	UTSW	15	35,422,600 (GRCm39)	missense	probably damaging	1.00
R1386:Vps13b	UTSW	15	35,923,458 (GRCm39)	missense	probably damaging	0.99
R1403:Vps13b	UTSW	15	35,709,268 (GRCm39)	splice site	probably benign
R1453:Vps13b	UTSW	15	35,422,590 (GRCm39)	missense	probably damaging	0.97
R1464:Vps13b	UTSW	15	35,709,630 (GRCm39)	missense	probably benign	0.14
R1464:Vps13b	UTSW	15	35,709,630 (GRCm39)	missense	probably benign	0.14
R1511:Vps13b	UTSW	15	35,841,719 (GRCm39)	missense	probably benign	0.00
R1511:Vps13b	UTSW	15	35,840,121 (GRCm39)	missense	probably damaging	0.99
R1513:Vps13b	UTSW	15	35,438,876 (GRCm39)	nonsense	probably null
R1536:Vps13b	UTSW	15	35,875,712 (GRCm39)	missense	probably damaging	0.98
R1537:Vps13b	UTSW	15	35,792,327 (GRCm39)	missense	possibly damaging	0.62
R1558:Vps13b	UTSW	15	35,534,465 (GRCm39)	missense	probably damaging	1.00
R1601:Vps13b	UTSW	15	35,642,582 (GRCm39)	missense	probably benign	0.11
R1653:Vps13b	UTSW	15	35,607,418 (GRCm39)	nonsense	probably null
R1695:Vps13b	UTSW	15	35,576,667 (GRCm39)	missense	probably benign	0.05
R1760:Vps13b	UTSW	15	35,884,765 (GRCm39)	missense	possibly damaging	0.54
R1785:Vps13b	UTSW	15	35,879,937 (GRCm39)	missense	probably damaging	1.00
R1786:Vps13b	UTSW	15	35,879,937 (GRCm39)	missense	probably damaging	1.00
R1803:Vps13b	UTSW	15	35,430,351 (GRCm39)	nonsense	probably null
R1804:Vps13b	UTSW	15	35,917,283 (GRCm39)	missense	probably damaging	1.00
R1808:Vps13b	UTSW	15	35,792,205 (GRCm39)	missense	probably benign	0.00
R1817:Vps13b	UTSW	15	35,910,788 (GRCm39)	missense	possibly damaging	0.86
R1818:Vps13b	UTSW	15	35,877,723 (GRCm39)	missense	probably benign	0.00
R1836:Vps13b	UTSW	15	35,910,378 (GRCm39)	missense	probably damaging	0.99
R1850:Vps13b	UTSW	15	35,675,105 (GRCm39)	splice site	probably benign
R1884:Vps13b	UTSW	15	35,430,437 (GRCm39)	splice site	probably benign
R1938:Vps13b	UTSW	15	35,709,653 (GRCm39)	missense	probably damaging	1.00
R1955:Vps13b	UTSW	15	35,925,554 (GRCm39)	critical splice donor site	probably null
R1956:Vps13b	UTSW	15	35,869,553 (GRCm39)	missense	probably damaging	1.00
R1958:Vps13b	UTSW	15	35,878,835 (GRCm39)	missense	probably damaging	0.99
R2013:Vps13b	UTSW	15	35,607,288 (GRCm39)	missense	probably damaging	0.99
R2014:Vps13b	UTSW	15	35,607,288 (GRCm39)	missense	probably damaging	0.99
R2015:Vps13b	UTSW	15	35,607,288 (GRCm39)	missense	probably damaging	0.99
R2038:Vps13b	UTSW	15	35,884,887 (GRCm39)	missense	probably damaging	1.00
R2058:Vps13b	UTSW	15	35,841,593 (GRCm39)	missense	probably damaging	1.00
R2082:Vps13b	UTSW	15	35,910,892 (GRCm39)	missense	possibly damaging	0.70
R2087:Vps13b	UTSW	15	35,597,639 (GRCm39)	missense	probably damaging	0.99
R2124:Vps13b	UTSW	15	35,646,226 (GRCm39)	missense	probably benign	0.08
R2130:Vps13b	UTSW	15	35,671,546 (GRCm39)	missense	probably benign	0.13
R2168:Vps13b	UTSW	15	35,792,334 (GRCm39)	missense	probably damaging	1.00
R2168:Vps13b	UTSW	15	35,792,335 (GRCm39)	missense	probably damaging	1.00
R2171:Vps13b	UTSW	15	35,887,343 (GRCm39)	missense	probably benign	0.44
R2221:Vps13b	UTSW	15	35,884,743 (GRCm39)	missense	probably benign
R2263:Vps13b	UTSW	15	35,646,327 (GRCm39)	missense	probably benign	0.02
R2289:Vps13b	UTSW	15	35,572,251 (GRCm39)	missense	probably damaging	1.00
R2316:Vps13b	UTSW	15	35,675,045 (GRCm39)	nonsense	probably null
R2351:Vps13b	UTSW	15	35,869,457 (GRCm39)	missense	probably damaging	1.00
R2512:Vps13b	UTSW	15	35,884,701 (GRCm39)	missense	probably benign	0.35
R3054:Vps13b	UTSW	15	35,646,507 (GRCm39)	missense	probably damaging	0.99
R3055:Vps13b	UTSW	15	35,646,507 (GRCm39)	missense	probably damaging	0.99
R3196:Vps13b	UTSW	15	35,869,541 (GRCm39)	missense	probably damaging	1.00
R3236:Vps13b	UTSW	15	35,910,450 (GRCm39)	missense	probably benign	0.40
R3404:Vps13b	UTSW	15	35,926,200 (GRCm39)	missense	probably damaging	1.00
R3722:Vps13b	UTSW	15	35,671,528 (GRCm39)	missense	probably damaging	0.99
R4077:Vps13b	UTSW	15	35,455,274 (GRCm39)	missense	probably damaging	0.99
R4153:Vps13b	UTSW	15	35,792,173 (GRCm39)	splice site	probably null
R4224:Vps13b	UTSW	15	35,876,565 (GRCm39)	missense	probably damaging	0.99
R4408:Vps13b	UTSW	15	35,709,440 (GRCm39)	missense	probably damaging	0.98
R4431:Vps13b	UTSW	15	35,770,899 (GRCm39)	missense	probably damaging	1.00
R4449:Vps13b	UTSW	15	35,876,939 (GRCm39)	missense	possibly damaging	0.86
R4508:Vps13b	UTSW	15	35,709,819 (GRCm39)	missense	possibly damaging	0.80
R4631:Vps13b	UTSW	15	35,646,278 (GRCm39)	missense	possibly damaging	0.95
R4655:Vps13b	UTSW	15	35,770,835 (GRCm39)	missense	probably benign
R4666:Vps13b	UTSW	15	35,640,690 (GRCm39)	missense	probably benign	0.13
R4684:Vps13b	UTSW	15	35,879,967 (GRCm39)	missense	probably benign
R4684:Vps13b	UTSW	15	35,841,487 (GRCm39)	missense	probably benign
R4684:Vps13b	UTSW	15	35,646,324 (GRCm39)	missense	probably damaging	0.98
R4721:Vps13b	UTSW	15	35,910,864 (GRCm39)	nonsense	probably null
R4771:Vps13b	UTSW	15	35,910,946 (GRCm39)	missense	probably damaging	1.00
R4830:Vps13b	UTSW	15	35,452,370 (GRCm39)	missense	possibly damaging	0.94
R4835:Vps13b	UTSW	15	35,869,518 (GRCm39)	missense	probably damaging	1.00
R4835:Vps13b	UTSW	15	35,910,439 (GRCm39)	missense	probably benign
R4857:Vps13b	UTSW	15	35,456,800 (GRCm39)	missense	probably benign	0.01
R4891:Vps13b	UTSW	15	35,640,661 (GRCm39)	splice site	probably null
R5095:Vps13b	UTSW	15	35,923,348 (GRCm39)	missense	probably damaging	1.00
R5110:Vps13b	UTSW	15	35,770,955 (GRCm39)	missense	probably damaging	0.99
R5147:Vps13b	UTSW	15	35,456,824 (GRCm39)	missense	probably benign	0.32
R5153:Vps13b	UTSW	15	35,422,599 (GRCm39)	missense	probably damaging	0.99
R5257:Vps13b	UTSW	15	35,794,567 (GRCm39)	missense	possibly damaging	0.75
R5258:Vps13b	UTSW	15	35,794,567 (GRCm39)	missense	possibly damaging	0.75
R5296:Vps13b	UTSW	15	35,876,559 (GRCm39)	missense	probably damaging	1.00
R5386:Vps13b	UTSW	15	35,640,674 (GRCm39)	critical splice acceptor site	probably null
R5396:Vps13b	UTSW	15	35,887,094 (GRCm39)	missense	probably damaging	0.99
R5412:Vps13b	UTSW	15	35,533,531 (GRCm39)	missense	probably damaging	1.00
R5488:Vps13b	UTSW	15	35,770,688 (GRCm39)	missense	probably benign
R5489:Vps13b	UTSW	15	35,770,688 (GRCm39)	missense	probably benign
R5503:Vps13b	UTSW	15	35,452,312 (GRCm39)	missense	probably damaging	0.97
R5575:Vps13b	UTSW	15	35,930,065 (GRCm39)	missense	probably damaging	1.00
R5781:Vps13b	UTSW	15	35,794,181 (GRCm39)	missense	probably damaging	0.97
R5872:Vps13b	UTSW	15	35,869,497 (GRCm39)	missense	possibly damaging	0.56
R5876:Vps13b	UTSW	15	35,917,207 (GRCm39)	missense	probably damaging	0.99
R5994:Vps13b	UTSW	15	35,875,918 (GRCm39)	missense	probably damaging	1.00
R6031:Vps13b	UTSW	15	35,472,114 (GRCm39)	missense	probably damaging	1.00
R6031:Vps13b	UTSW	15	35,472,114 (GRCm39)	missense	probably damaging	1.00
R6045:Vps13b	UTSW	15	35,671,462 (GRCm39)	missense	probably damaging	0.99
R6143:Vps13b	UTSW	15	35,668,884 (GRCm39)	missense	probably damaging	0.99
R6147:Vps13b	UTSW	15	35,930,177 (GRCm39)	missense	probably benign	0.16
R6218:Vps13b	UTSW	15	35,770,610 (GRCm39)	missense	probably benign	0.00
R6447:Vps13b	UTSW	15	35,572,272 (GRCm39)	missense	probably benign	0.02
R6555:Vps13b	UTSW	15	35,846,993 (GRCm39)	missense	probably damaging	1.00
R6578:Vps13b	UTSW	15	35,446,247 (GRCm39)	missense	probably damaging	0.99
R6640:Vps13b	UTSW	15	35,617,842 (GRCm39)	missense	possibly damaging	0.93
R6645:Vps13b	UTSW	15	35,910,451 (GRCm39)	missense	probably benign	0.25
R6711:Vps13b	UTSW	15	35,887,395 (GRCm39)	missense	probably damaging	1.00
R6727:Vps13b	UTSW	15	35,770,829 (GRCm39)	missense	probably benign	0.19
R6737:Vps13b	UTSW	15	35,910,757 (GRCm39)	missense	probably damaging	1.00
R6844:Vps13b	UTSW	15	35,877,736 (GRCm39)	missense	probably benign	0.06
R6849:Vps13b	UTSW	15	35,905,455 (GRCm39)	missense	probably damaging	1.00
R6861:Vps13b	UTSW	15	35,576,541 (GRCm39)	missense	probably damaging	0.99
R6938:Vps13b	UTSW	15	35,423,344 (GRCm39)	missense	probably damaging	0.99
R6943:Vps13b	UTSW	15	35,448,835 (GRCm39)	missense	possibly damaging	0.95
R6989:Vps13b	UTSW	15	35,448,727 (GRCm39)	missense	probably benign	0.02
R7092:Vps13b	UTSW	15	35,640,780 (GRCm39)	missense	probably damaging	1.00
R7232:Vps13b	UTSW	15	35,877,703 (GRCm39)	missense	probably damaging	1.00
R7307:Vps13b	UTSW	15	35,841,691 (GRCm39)	missense	probably benign
R7400:Vps13b	UTSW	15	35,379,046 (GRCm39)	missense	probably damaging	1.00
R7414:Vps13b	UTSW	15	35,910,973 (GRCm39)	missense	probably damaging	1.00
R7497:Vps13b	UTSW	15	35,876,843 (GRCm39)	missense	probably benign	0.38
R7500:Vps13b	UTSW	15	35,910,670 (GRCm39)	missense	possibly damaging	0.74
R7603:Vps13b	UTSW	15	35,576,585 (GRCm39)	missense	probably damaging	0.98
R7605:Vps13b	UTSW	15	35,770,792 (GRCm39)	missense	probably damaging	0.97
R7849:Vps13b	UTSW	15	35,423,378 (GRCm39)	missense	probably damaging	0.99
R7984:Vps13b	UTSW	15	35,880,059 (GRCm39)	missense	probably benign
R8094:Vps13b	UTSW	15	35,669,052 (GRCm39)	critical splice donor site	probably null
R8097:Vps13b	UTSW	15	35,709,492 (GRCm39)	missense	probably benign	0.38
R8131:Vps13b	UTSW	15	35,372,255 (GRCm39)	critical splice donor site	probably null
R8139:Vps13b	UTSW	15	35,607,418 (GRCm39)	nonsense	probably null
R8174:Vps13b	UTSW	15	35,709,456 (GRCm39)	nonsense	probably null
R8225:Vps13b	UTSW	15	35,794,528 (GRCm39)	missense	probably damaging	0.99
R8239:Vps13b	UTSW	15	35,597,550 (GRCm39)	missense	probably damaging	1.00
R8244:Vps13b	UTSW	15	35,917,349 (GRCm39)	missense	probably damaging	1.00
R8303:Vps13b	UTSW	15	35,640,063 (GRCm39)	missense	probably damaging	1.00
R8311:Vps13b	UTSW	15	35,887,100 (GRCm39)	missense	probably benign	0.37
R8443:Vps13b	UTSW	15	35,455,246 (GRCm39)	missense	probably benign
R8494:Vps13b	UTSW	15	35,422,594 (GRCm39)	missense	probably damaging	0.99
R8499:Vps13b	UTSW	15	35,841,466 (GRCm39)	missense	probably damaging	1.00
R8506:Vps13b	UTSW	15	35,446,891 (GRCm39)	missense	probably benign	0.31
R8559:Vps13b	UTSW	15	35,876,788 (GRCm39)	missense	probably damaging	1.00
R8686:Vps13b	UTSW	15	35,925,535 (GRCm39)	missense	probably damaging	0.99
R8782:Vps13b	UTSW	15	35,422,483 (GRCm39)	missense	possibly damaging	0.93
R8806:Vps13b	UTSW	15	35,472,212 (GRCm39)	critical splice donor site	probably benign
R8824:Vps13b	UTSW	15	35,533,445 (GRCm39)	missense	probably damaging	0.99
R9024:Vps13b	UTSW	15	35,923,470 (GRCm39)	missense	probably damaging	0.97
R9038:Vps13b	UTSW	15	35,875,931 (GRCm39)	missense	possibly damaging	0.70
R9054:Vps13b	UTSW	15	35,422,537 (GRCm39)	missense	probably damaging	1.00
R9091:Vps13b	UTSW	15	35,770,919 (GRCm39)	missense	probably benign	0.13
R9129:Vps13b	UTSW	15	35,448,793 (GRCm39)	missense	probably damaging	1.00
R9214:Vps13b	UTSW	15	35,623,892 (GRCm39)	missense	probably damaging	0.99
R9237:Vps13b	UTSW	15	35,841,479 (GRCm39)	missense	probably damaging	1.00
R9256:Vps13b	UTSW	15	35,623,925 (GRCm39)	missense	possibly damaging	0.95
R9270:Vps13b	UTSW	15	35,770,919 (GRCm39)	missense	probably benign	0.13
R9279:Vps13b	UTSW	15	35,572,290 (GRCm39)	missense	probably damaging	0.97
R9291:Vps13b	UTSW	15	35,847,059 (GRCm39)	missense	probably damaging	1.00
R9342:Vps13b	UTSW	15	35,455,200 (GRCm39)	missense	possibly damaging	0.94
R9404:Vps13b	UTSW	15	35,876,565 (GRCm39)	missense	probably damaging	1.00
R9488:Vps13b	UTSW	15	35,447,880 (GRCm39)	missense	possibly damaging	0.77
R9509:Vps13b	UTSW	15	35,841,457 (GRCm39)	missense	possibly damaging	0.79
R9610:Vps13b	UTSW	15	35,642,555 (GRCm39)	missense	possibly damaging	0.85
R9611:Vps13b	UTSW	15	35,642,555 (GRCm39)	missense	possibly damaging	0.85
R9658:Vps13b	UTSW	15	35,623,774 (GRCm39)	missense	probably benign	0.00
R9674:Vps13b	UTSW	15	35,607,380 (GRCm39)	missense	probably damaging	0.98
R9767:Vps13b	UTSW	15	35,910,403 (GRCm39)	missense	probably damaging	1.00
R9797:Vps13b	UTSW	15	35,675,022 (GRCm39)	missense	probably damaging	1.00
RF020:Vps13b	UTSW	15	35,925,552 (GRCm39)	missense	probably null	1.00
X0026:Vps13b	UTSW	15	35,910,792 (GRCm39)	missense	probably damaging	1.00
X0028:Vps13b	UTSW	15	35,709,577 (GRCm39)	missense	probably benign	0.00
Z1177:Vps13b	UTSW	15	35,669,031 (GRCm39)	nonsense	probably null

Predicted Primers

PCR Primer
(F):5'- TGAGTCCCTGGAGAGTTAGG -3'
(R):5'- TGACACCAGGGTTCTCACAG -3'

Sequencing Primer
(F):5'- TCCCTGGAGAGTTAGGAAGTAG -3'
(R):5'- GGGTTCTCACAGCTCACTTTAGAAAC -3'

Posted On

2022-10-06