Incidental Mutation 'R9697:Pik3c2g'
| ID |
729367 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pik3c2g
|
| Ensembl Gene |
ENSMUSG00000030228 |
| Gene Name |
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma |
| Synonyms |
|
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.118)
|
| Stock # |
R9697 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
139591070-139915010 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 139913517 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Methionine
at position 972
(V972M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000107499
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000087657]
[ENSMUST00000111868]
[ENSMUST00000218528]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000087657
AA Change: V604M
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000084939
Gene: ENSMUSG00000030228
AA Change: V604M
| Domain | Start | End | E-Value | Type |
|---|
|
PI3Kc
|
125 |
387 |
2.11e-109 |
SMART |
|
PX
|
411 |
515 |
1.24e-21 |
SMART |
|
C2
|
550 |
647 |
1.34e-7 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000111868
AA Change: V972M
|
| SMART Domains |
Protein: ENSMUSP00000107499
Gene: ENSMUSG00000030228
AA Change: V972M
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1e8xa2
|
1 |
83 |
4e-16 |
SMART |
|
PI3Ka
|
103 |
288 |
7.6e-29 |
SMART |
|
PI3Kc
|
375 |
637 |
2.11e-109 |
SMART |
|
PX
|
661 |
765 |
1.24e-21 |
SMART |
|
C2
|
800 |
897 |
1.34e-7 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000218528
AA Change: V854M
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 98.6%
- 20x: 96.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
PHENOTYPE: Mice homozygous for a knock-out allelel exhibit reduced liver glucogen accumulation, hyperlipidemia, adiposity and insulin resistance with age or after consumption of a high-fat diet. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 62 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1600012H06Rik |
C |
T |
17: 15,163,769 (GRCm39) |
|
probably benign |
Het |
| 9330182O14Rik |
C |
T |
15: 40,005,500 (GRCm39) |
|
probably benign |
Het |
| Adamts19 |
C |
A |
18: 59,101,834 (GRCm39) |
P635T |
probably damaging |
Het |
| Adgrf1 |
T |
C |
17: 43,625,362 (GRCm39) |
W857R |
possibly damaging |
Het |
| Ak9 |
T |
G |
10: 41,298,968 (GRCm39) |
Y1556* |
probably null |
Het |
| Ang2 |
T |
C |
14: 51,433,326 (GRCm39) |
I19V |
probably benign |
Het |
| Ano3 |
T |
A |
2: 110,496,253 (GRCm39) |
T834S |
probably damaging |
Het |
| As3mt |
A |
T |
19: 46,708,420 (GRCm39) |
I236F |
probably benign |
Het |
| Asns |
A |
T |
6: 7,689,268 (GRCm39) |
I78N |
probably damaging |
Het |
| Bet1 |
G |
A |
6: 4,082,471 (GRCm39) |
T44M |
probably damaging |
Het |
| Cabyr |
T |
C |
18: 12,884,407 (GRCm39) |
V298A |
possibly damaging |
Het |
| Cacna1c |
A |
G |
6: 118,589,598 (GRCm39) |
V1601A |
|
Het |
| Ccni |
A |
T |
5: 93,350,201 (GRCm39) |
M26K |
probably damaging |
Het |
| Cdhr2 |
T |
C |
13: 54,867,679 (GRCm39) |
I503T |
probably damaging |
Het |
| Cfap54 |
T |
C |
10: 92,792,851 (GRCm39) |
K1754R |
unknown |
Het |
| Cfap69 |
A |
G |
5: 5,676,041 (GRCm39) |
V218A |
possibly damaging |
Het |
| Clcn3 |
A |
G |
8: 61,372,518 (GRCm39) |
L741P |
probably damaging |
Het |
| Cntnap1 |
T |
C |
11: 101,068,828 (GRCm39) |
F124L |
possibly damaging |
Het |
| Col20a1 |
G |
A |
2: 180,641,577 (GRCm39) |
G673D |
probably benign |
Het |
| Col4a2 |
A |
G |
8: 11,487,628 (GRCm39) |
I977V |
probably benign |
Het |
| Cyp3a59 |
A |
T |
5: 146,031,190 (GRCm39) |
I118F |
probably damaging |
Het |
| Dgcr8 |
A |
T |
16: 18,098,283 (GRCm39) |
D369E |
probably benign |
Het |
| Dhtkd1 |
T |
C |
2: 5,919,651 (GRCm39) |
T577A |
probably benign |
Het |
| Dock2 |
A |
T |
11: 34,204,417 (GRCm39) |
M1375K |
probably benign |
Het |
| Fa2h |
G |
A |
8: 112,074,659 (GRCm39) |
H315Y |
probably damaging |
Het |
| Foxd2 |
G |
A |
4: 114,765,684 (GRCm39) |
P112L |
unknown |
Het |
| Gin1 |
A |
G |
1: 97,712,897 (GRCm39) |
I317V |
probably benign |
Het |
| Gpr180 |
G |
A |
14: 118,391,302 (GRCm39) |
G235R |
probably damaging |
Het |
| H2-T3 |
T |
A |
17: 36,500,744 (GRCm39) |
Y33F |
probably damaging |
Het |
| Idh2 |
TCCCAGG |
T |
7: 79,748,079 (GRCm39) |
|
probably benign |
Het |
| Il12rb1 |
G |
A |
8: 71,263,874 (GRCm39) |
W145* |
probably null |
Het |
| Il6ra |
A |
G |
3: 89,785,219 (GRCm39) |
V330A |
probably benign |
Het |
| Impdh2 |
T |
C |
9: 108,438,847 (GRCm39) |
S67P |
possibly damaging |
Het |
| Ltbp3 |
T |
A |
19: 5,792,521 (GRCm39) |
S85T |
probably benign |
Het |
| Magi3 |
A |
G |
3: 103,956,458 (GRCm39) |
|
probably null |
Het |
| Mettl4 |
T |
A |
17: 95,034,806 (GRCm39) |
I430F |
probably damaging |
Het |
| Mmd |
T |
A |
11: 90,167,579 (GRCm39) |
F203I |
probably damaging |
Het |
| Nlgn1 |
T |
C |
3: 25,494,035 (GRCm39) |
T305A |
possibly damaging |
Het |
| Ntn1 |
A |
G |
11: 68,168,356 (GRCm39) |
V367A |
probably damaging |
Het |
| Or2w1b |
A |
T |
13: 21,299,892 (GRCm39) |
H10L |
probably benign |
Het |
| Or5b107 |
G |
A |
19: 13,142,888 (GRCm39) |
C170Y |
possibly damaging |
Het |
| Pcdh12 |
T |
C |
18: 38,415,022 (GRCm39) |
H701R |
possibly damaging |
Het |
| Pcgf3 |
G |
A |
5: 108,621,773 (GRCm39) |
|
probably null |
Het |
| Pink1 |
A |
G |
4: 138,041,323 (GRCm39) |
C563R |
possibly damaging |
Het |
| Prol1 |
A |
T |
5: 88,466,426 (GRCm39) |
N3I |
probably benign |
Het |
| Ptpro |
T |
G |
6: 137,363,288 (GRCm39) |
I474S |
probably damaging |
Het |
| Rabgef1 |
A |
G |
5: 130,241,781 (GRCm39) |
E395G |
probably benign |
Het |
| Rpgrip1l |
G |
T |
8: 91,987,391 (GRCm39) |
H889N |
possibly damaging |
Het |
| Sapcd2 |
T |
A |
2: 25,262,925 (GRCm39) |
C161* |
probably null |
Het |
| Sbsn |
GAAAAGGAAGCAGAAAAAGTGGCCCATGGGGTACAGAATGGAGTCAACCAGGCTCAAAAGGAAGCAGAAAAAGTGGCCCATGGGGTACAGAATGGAGTCAACCAGGCTCAAAAGGAAGCAGAAAAAGTGGCCCATGGGGTACAGAATGGAGTCAACCAGGCTCAAAAGGAAGCAGAAAAAGTGGCCCA |
GAAAAGGAAGCAGAAAAAGTGGCCCATGGGGTACAGAATGGAGTCAACCAGGCTCAAAAGGAAGCAGAAAAAGTGGCCCATGGGGTACAGAATGGAGTCAACCAGGCTCAAAAGGAAGCAGAAAAAGTGGCCCA |
7: 30,452,391 (GRCm39) |
|
probably benign |
Het |
| Spen |
A |
G |
4: 141,196,275 (GRCm39) |
L3625P |
probably damaging |
Het |
| Stil |
T |
C |
4: 114,878,701 (GRCm39) |
I379T |
probably benign |
Het |
| Stim1 |
A |
G |
7: 102,078,014 (GRCm39) |
D172G |
|
Het |
| Timm50 |
A |
G |
7: 28,010,350 (GRCm39) |
L68P |
probably damaging |
Het |
| Tlr9 |
C |
T |
9: 106,100,723 (GRCm39) |
R5* |
probably null |
Het |
| Top1mt |
A |
T |
15: 75,547,874 (GRCm39) |
Y71N |
probably damaging |
Het |
| Trpv4 |
A |
G |
5: 114,771,285 (GRCm39) |
Y415H |
possibly damaging |
Het |
| Try10 |
C |
T |
6: 41,331,041 (GRCm39) |
|
probably benign |
Het |
| Uhrf2 |
A |
G |
19: 30,063,780 (GRCm39) |
E581G |
probably damaging |
Het |
| Usp17lb |
G |
A |
7: 104,490,495 (GRCm39) |
T144I |
possibly damaging |
Het |
| Vmn1r64 |
T |
C |
7: 5,886,859 (GRCm39) |
N228S |
probably benign |
Het |
| Vwa1 |
G |
A |
4: 155,857,336 (GRCm39) |
P154L |
probably damaging |
Het |
|
| Other mutations in Pik3c2g |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00159:Pik3c2g
|
APN |
6 |
139,841,851 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01355:Pik3c2g
|
APN |
6 |
139,798,583 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01579:Pik3c2g
|
APN |
6 |
139,700,467 (GRCm39) |
nonsense |
probably null |
|
|
IGL01580:Pik3c2g
|
APN |
6 |
139,599,514 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01587:Pik3c2g
|
APN |
6 |
139,700,467 (GRCm39) |
nonsense |
probably null |
|
|
IGL01813:Pik3c2g
|
APN |
6 |
139,599,407 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL02218:Pik3c2g
|
APN |
6 |
139,806,081 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02479:Pik3c2g
|
APN |
6 |
139,863,730 (GRCm39) |
missense |
probably benign |
0.40 |
|
IGL02480:Pik3c2g
|
APN |
6 |
139,798,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02721:Pik3c2g
|
APN |
6 |
139,682,699 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL02967:Pik3c2g
|
APN |
6 |
139,913,554 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03221:Pik3c2g
|
APN |
6 |
139,718,133 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
FR4304:Pik3c2g
|
UTSW |
6 |
139,612,654 (GRCm39) |
frame shift |
probably null |
|
|
FR4340:Pik3c2g
|
UTSW |
6 |
139,612,654 (GRCm39) |
frame shift |
probably null |
|
|
FR4976:Pik3c2g
|
UTSW |
6 |
139,612,652 (GRCm39) |
frame shift |
probably null |
|
|
IGL02837:Pik3c2g
|
UTSW |
6 |
139,603,562 (GRCm39) |
nonsense |
probably null |
|
|
PIT4531001:Pik3c2g
|
UTSW |
6 |
139,805,096 (GRCm39) |
missense |
|
|
|
R0002:Pik3c2g
|
UTSW |
6 |
139,714,471 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0081:Pik3c2g
|
UTSW |
6 |
139,903,519 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0098:Pik3c2g
|
UTSW |
6 |
139,639,441 (GRCm39) |
missense |
unknown |
|
|
R0719:Pik3c2g
|
UTSW |
6 |
139,606,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0740:Pik3c2g
|
UTSW |
6 |
139,610,791 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0837:Pik3c2g
|
UTSW |
6 |
139,903,425 (GRCm39) |
splice site |
probably benign |
|
|
R0840:Pik3c2g
|
UTSW |
6 |
139,841,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1306:Pik3c2g
|
UTSW |
6 |
139,718,154 (GRCm39) |
missense |
probably benign |
|
|
R1501:Pik3c2g
|
UTSW |
6 |
139,789,796 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1591:Pik3c2g
|
UTSW |
6 |
139,693,904 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1666:Pik3c2g
|
UTSW |
6 |
139,612,634 (GRCm39) |
intron |
probably benign |
|
|
R1907:Pik3c2g
|
UTSW |
6 |
139,789,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1970:Pik3c2g
|
UTSW |
6 |
139,846,112 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1982:Pik3c2g
|
UTSW |
6 |
139,599,546 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2171:Pik3c2g
|
UTSW |
6 |
139,801,012 (GRCm39) |
nonsense |
probably null |
|
|
R2188:Pik3c2g
|
UTSW |
6 |
139,798,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3777:Pik3c2g
|
UTSW |
6 |
139,599,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3778:Pik3c2g
|
UTSW |
6 |
139,599,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3965:Pik3c2g
|
UTSW |
6 |
139,801,018 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4076:Pik3c2g
|
UTSW |
6 |
139,798,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4078:Pik3c2g
|
UTSW |
6 |
139,612,608 (GRCm39) |
intron |
probably benign |
|
|
R4108:Pik3c2g
|
UTSW |
6 |
139,676,096 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4461:Pik3c2g
|
UTSW |
6 |
139,787,407 (GRCm39) |
intron |
probably benign |
|
|
R4474:Pik3c2g
|
UTSW |
6 |
139,610,749 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4509:Pik3c2g
|
UTSW |
6 |
139,665,732 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4646:Pik3c2g
|
UTSW |
6 |
139,665,744 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4732:Pik3c2g
|
UTSW |
6 |
139,881,711 (GRCm39) |
missense |
probably benign |
0.28 |
|
R4733:Pik3c2g
|
UTSW |
6 |
139,881,711 (GRCm39) |
missense |
probably benign |
0.28 |
|
R4854:Pik3c2g
|
UTSW |
6 |
139,714,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4928:Pik3c2g
|
UTSW |
6 |
139,913,528 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4959:Pik3c2g
|
UTSW |
6 |
139,789,657 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R4973:Pik3c2g
|
UTSW |
6 |
139,789,657 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5032:Pik3c2g
|
UTSW |
6 |
139,841,928 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5071:Pik3c2g
|
UTSW |
6 |
139,665,873 (GRCm39) |
missense |
probably null |
0.00 |
|
R5072:Pik3c2g
|
UTSW |
6 |
139,665,873 (GRCm39) |
missense |
probably null |
0.00 |
|
R5073:Pik3c2g
|
UTSW |
6 |
139,665,873 (GRCm39) |
missense |
probably null |
0.00 |
|
R5074:Pik3c2g
|
UTSW |
6 |
139,665,873 (GRCm39) |
missense |
probably null |
0.00 |
|
R5107:Pik3c2g
|
UTSW |
6 |
139,612,623 (GRCm39) |
intron |
probably benign |
|
|
R5186:Pik3c2g
|
UTSW |
6 |
139,599,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5253:Pik3c2g
|
UTSW |
6 |
139,841,983 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5359:Pik3c2g
|
UTSW |
6 |
139,599,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5394:Pik3c2g
|
UTSW |
6 |
139,665,808 (GRCm39) |
missense |
probably benign |
|
|
R5417:Pik3c2g
|
UTSW |
6 |
139,682,669 (GRCm39) |
missense |
probably benign |
|
|
R5435:Pik3c2g
|
UTSW |
6 |
139,661,581 (GRCm39) |
splice site |
probably null |
|
|
R5580:Pik3c2g
|
UTSW |
6 |
139,603,531 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5664:Pik3c2g
|
UTSW |
6 |
139,682,733 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5908:Pik3c2g
|
UTSW |
6 |
139,714,436 (GRCm39) |
missense |
|
|
|
R5914:Pik3c2g
|
UTSW |
6 |
139,599,477 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6046:Pik3c2g
|
UTSW |
6 |
139,842,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6046:Pik3c2g
|
UTSW |
6 |
139,599,137 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6298:Pik3c2g
|
UTSW |
6 |
139,603,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6382:Pik3c2g
|
UTSW |
6 |
139,665,724 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6480:Pik3c2g
|
UTSW |
6 |
139,676,195 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6917:Pik3c2g
|
UTSW |
6 |
139,841,899 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6929:Pik3c2g
|
UTSW |
6 |
139,903,502 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7022:Pik3c2g
|
UTSW |
6 |
139,599,061 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7144:Pik3c2g
|
UTSW |
6 |
139,606,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7213:Pik3c2g
|
UTSW |
6 |
139,805,990 (GRCm39) |
missense |
|
|
|
R7215:Pik3c2g
|
UTSW |
6 |
139,700,589 (GRCm39) |
missense |
|
|
|
R7332:Pik3c2g
|
UTSW |
6 |
139,841,981 (GRCm39) |
missense |
|
|
|
R7357:Pik3c2g
|
UTSW |
6 |
139,610,791 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7359:Pik3c2g
|
UTSW |
6 |
139,913,620 (GRCm39) |
missense |
unknown |
|
|
R7385:Pik3c2g
|
UTSW |
6 |
139,801,079 (GRCm39) |
missense |
|
|
|
R7455:Pik3c2g
|
UTSW |
6 |
139,913,643 (GRCm39) |
missense |
unknown |
|
|
R7651:Pik3c2g
|
UTSW |
6 |
139,599,070 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7888:Pik3c2g
|
UTSW |
6 |
139,842,470 (GRCm39) |
missense |
|
|
|
R7923:Pik3c2g
|
UTSW |
6 |
139,610,791 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7964:Pik3c2g
|
UTSW |
6 |
139,827,786 (GRCm39) |
missense |
|
|
|
R8005:Pik3c2g
|
UTSW |
6 |
139,599,067 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8371:Pik3c2g
|
UTSW |
6 |
139,881,782 (GRCm39) |
missense |
unknown |
|
|
R8724:Pik3c2g
|
UTSW |
6 |
139,913,619 (GRCm39) |
missense |
unknown |
|
|
R8733:Pik3c2g
|
UTSW |
6 |
139,714,426 (GRCm39) |
nonsense |
probably null |
|
|
R8809:Pik3c2g
|
UTSW |
6 |
139,714,436 (GRCm39) |
missense |
|
|
|
R8888:Pik3c2g
|
UTSW |
6 |
139,676,092 (GRCm39) |
nonsense |
probably null |
|
|
R8931:Pik3c2g
|
UTSW |
6 |
139,821,093 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9188:Pik3c2g
|
UTSW |
6 |
139,599,401 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9336:Pik3c2g
|
UTSW |
6 |
139,821,161 (GRCm39) |
missense |
|
|
|
R9383:Pik3c2g
|
UTSW |
6 |
139,827,742 (GRCm39) |
nonsense |
probably null |
|
|
R9524:Pik3c2g
|
UTSW |
6 |
139,606,768 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9531:Pik3c2g
|
UTSW |
6 |
139,841,926 (GRCm39) |
missense |
|
|
|
R9630:Pik3c2g
|
UTSW |
6 |
139,599,237 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9708:Pik3c2g
|
UTSW |
6 |
139,606,865 (GRCm39) |
missense |
probably benign |
|
|
R9717:Pik3c2g
|
UTSW |
6 |
139,841,910 (GRCm39) |
missense |
|
|
|
RF015:Pik3c2g
|
UTSW |
6 |
139,700,497 (GRCm39) |
missense |
|
|
|
RF032:Pik3c2g
|
UTSW |
6 |
139,612,656 (GRCm39) |
frame shift |
probably null |
|
|
X0024:Pik3c2g
|
UTSW |
6 |
139,805,984 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTAGAGCCTTGACTCTTCAGG -3'
(R):5'- TTGCATATGTGACAGAGGCAAG -3'
Sequencing Primer
(F):5'- CCTTGACTCTTCAGGGTTAACAC -3'
(R):5'- CTTAAGCAGTAATGCATACGCTCGTG -3'
|
| Posted On |
2022-10-06 |
Incidental Mutation