Mutagenetix > Incidental Mutation

Incidental Mutation 'R9709:Nbea'

729946

Institutional Source

Beutler Lab

Gene Symbol

Nbea

Ensembl Gene

ENSMUSG00000027799

Gene Name

neurobeachin

Synonyms

MMRRC Submission

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R9709 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

55532616-56091122 bp(-) (GRCm39)

Type of Mutation

nonsense

DNA Base Change (assembly)

T to A at 55693879 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Stop codon at position 2180 (K2180*)

Ref Sequence

ENSEMBL: ENSMUSP00000029374 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000029374] [ENSMUST00000075422]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000029374
AA Change: K2180*

SMART Domains

Protein: ENSMUSP00000029374
Gene: ENSMUSG00000027799
AA Change: K2180*

Domain	Start	End	E-Value	Type
low complexity region	19	40	N/A	INTRINSIC
Pfam:Laminin_G_3	228	393	2.8e-13	PFAM
Pfam:DUF4704	462	733	4e-113	PFAM
low complexity region	792	802	N/A	INTRINSIC
low complexity region	964	969	N/A	INTRINSIC
low complexity region	1781	1790	N/A	INTRINSIC
low complexity region	1791	1807	N/A	INTRINSIC
low complexity region	1835	1845	N/A	INTRINSIC
Pfam:DUF1088	1956	2122	3.5e-91	PFAM
Pfam:PH_BEACH	2148	2245	2.6e-32	PFAM
Beach	2276	2553	1.3e-205	SMART
WD40	2659	2696	2.12e2	SMART
WD40	2699	2742	2.22e0	SMART
WD40	2759	2798	9.21e0	SMART
WD40	2842	2880	2.88e-1	SMART
WD40	2883	2922	8.91e-1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000075422

SMART Domains

Protein: ENSMUSP00000074878
Gene: ENSMUSG00000056947

Domain	Start	End	E-Value	Type
Mab-21	61	347	3.59e-94	SMART

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.5%
20x: 98.3%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients with multiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined.[provided by RefSeq, Feb 2011]
PHENOTYPE: Mice homozygous for a gene trapped allele or transgene insertion die shortly after birth, are cyanotic, and exhibit no response to tactile stimuli, no spontaneous movement, and impaired CNS synaptic transmission. [provided by MGI curators]

Allele List at MGI

All alleles(4) : Gene trapped(3) Transgenic(1)

Other mutations in this stock

Total: 100 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1810062G17Rik	T	C	3: 36,530,356 (GRCm39)	S25P	unknown	Het
4921539E11Rik	A	G	4: 103,092,678 (GRCm39)	I268T	unknown	Het
4930507D05Rik	T	A	10: 62,285,581 (GRCm39)	C102S	unknown	Het
Abca14	T	A	7: 119,888,739 (GRCm39)	Y1228*	probably null	Het
Abca17	T	C	17: 24,517,934 (GRCm39)	I792V	probably benign	Het
Abca6	C	A	11: 110,102,589 (GRCm39)	L878F	probably benign	Het
Adk	C	A	14: 21,126,386 (GRCm39)	T4N	probably benign	Het
Ankrd40cl	G	A	11: 94,175,560 (GRCm39)	S65N	probably benign	Het
Atg2b	A	T	12: 105,611,140 (GRCm39)	F1264I	probably damaging	Het
Atl3	T	G	19: 7,507,921 (GRCm39)	S358A	probably benign	Het
Atp8a2	T	A	14: 60,271,187 (GRCm39)	Y248F	probably damaging	Het
Bcas3	T	C	11: 85,474,749 (GRCm39)	V785A	probably damaging	Het
Cckar	C	T	5: 53,860,201 (GRCm39)		probably null	Het
Cdc42se2	A	G	11: 54,614,417 (GRCm39)	F47L	probably benign	Het
Cfap58	T	C	19: 47,963,992 (GRCm39)	L540P	probably damaging	Het
Copg1	A	G	6: 87,868,957 (GRCm39)	E117G	probably benign	Het
Cstpp1	T	C	2: 91,112,099 (GRCm39)	Q250R	probably benign	Het
Cul2	C	T	18: 3,431,560 (GRCm39)	T655M	probably damaging	Het
Ddi2	T	C	4: 141,412,429 (GRCm39)	Q161R	probably benign	Het
Dffb	T	C	4: 154,059,121 (GRCm39)	Y52C	probably damaging	Het
Dll1	T	C	17: 15,591,198 (GRCm39)	Q249R	probably benign	Het
Dnmt3a	T	A	12: 3,957,701 (GRCm39)	I894N	probably damaging	Het
Fshr	G	A	17: 89,293,265 (GRCm39)	T471I	probably damaging	Het
Gabpb1	C	T	2: 126,500,488 (GRCm39)	V4I	probably benign	Het
Gbp9	T	C	5: 105,231,542 (GRCm39)	Q348R	probably damaging	Het
Gm21149	G	A	5: 15,677,110 (GRCm39)	S248F	unknown	Het
Gpr152	C	A	19: 4,192,640 (GRCm39)	H60Q	probably benign	Het
Hdac9	A	G	12: 34,362,602 (GRCm39)	S612P	probably benign	Het
Hhipl2	A	G	1: 183,199,747 (GRCm39)	D102G	possibly damaging	Het
Hspa9	A	G	18: 35,073,294 (GRCm39)	V530A	possibly damaging	Het
Igfbp7	T	C	5: 77,549,384 (GRCm39)	N173S	unknown	Het
Ighv1-75	A	G	12: 115,797,791 (GRCm39)	S44P	possibly damaging	Het
Iqgap3	C	A	3: 88,016,176 (GRCm39)	F986L	probably damaging	Het
Itgax	G	T	7: 127,735,500 (GRCm39)	G523W	probably damaging	Het
Itih3	A	G	14: 30,637,587 (GRCm39)		probably null	Het
Kcnb2	T	C	1: 15,780,523 (GRCm39)	I465T	probably benign	Het
Kmt2b	A	G	7: 30,279,228 (GRCm39)	V1478A	probably damaging	Het
Ky	A	T	9: 102,419,411 (GRCm39)	I473F	probably damaging	Het
Lbr	A	G	1: 181,666,034 (GRCm39)	V25A	probably damaging	Het
Ldlr	A	G	9: 21,657,135 (GRCm39)	T751A	probably benign	Het
Lrrtm4	A	G	6: 80,786,154 (GRCm39)	E587G	probably damaging	Het
Lvrn	A	C	18: 47,006,847 (GRCm39)		probably null	Het
Mast2	A	T	4: 116,173,044 (GRCm39)	C594S	probably damaging	Het
Mast4	A	G	13: 102,910,711 (GRCm39)	V644A	probably damaging	Het
Mcm5	T	C	8: 75,842,604 (GRCm39)	Y293H	probably damaging	Het
Mthfd2	A	T	6: 83,283,665 (GRCm39)	V339E	possibly damaging	Het
Muc4	A	T	16: 32,590,644 (GRCm39)	I881F		Het
Myo7a	A	G	7: 97,743,536 (GRCm39)	S372P	possibly damaging	Het
Neb	T	C	2: 52,101,507 (GRCm39)	D4621G	probably damaging	Het
Nefh	C	T	11: 4,890,042 (GRCm39)	S859N	probably benign	Het
Nek2	T	A	1: 191,563,289 (GRCm39)	H384Q	possibly damaging	Het
Nfkb2	A	G	19: 46,298,782 (GRCm39)	E645G	probably benign	Het
Nin	G	T	12: 70,149,468 (GRCm39)	P47Q		Het
Nit1	C	A	1: 171,171,307 (GRCm39)	K178N	probably benign	Het
Nrap	C	A	19: 56,317,452 (GRCm39)	K1433N	probably damaging	Het
Nrap	T	C	19: 56,317,453 (GRCm39)	K1433R	probably benign	Het
Nup85	A	G	11: 115,457,463 (GRCm39)	Y55C	possibly damaging	Het
Or2a14	G	T	6: 43,130,469 (GRCm39)	V77F	possibly damaging	Het
Pde1b	A	G	15: 103,411,985 (GRCm39)	K29E	probably benign	Het
Pheta2	G	T	15: 82,227,537 (GRCm39)	D19Y	probably damaging	Het
Pheta2	C	G	15: 82,227,535 (GRCm39)	A18G	probably damaging	Het
Pik3cg	A	T	12: 32,226,687 (GRCm39)	Y1067N	probably benign	Het
Pkd1l1	C	T	11: 8,799,016 (GRCm39)	G2249S	probably damaging	Het
Plppr4	T	A	3: 117,121,976 (GRCm39)	T201S	possibly damaging	Het
Polr1e	A	G	4: 45,018,678 (GRCm39)	T3A	probably benign	Het
Polr1has	A	T	17: 37,275,249 (GRCm39)	R7S	probably benign	Het
Pou6f2	G	T	13: 18,414,389 (GRCm39)	Q129K	unknown	Het
Ppil4	T	A	10: 7,675,341 (GRCm39)	D163E	probably benign	Het
Pradc1	A	G	6: 85,424,952 (GRCm39)	F82L	probably benign	Het
Psd3	T	C	8: 68,194,414 (GRCm39)	K784R	probably null	Het
Ptgs1	C	A	2: 36,141,204 (GRCm39)	S550R	probably damaging	Het
Pxylp1	A	G	9: 96,711,030 (GRCm39)	L153P	probably damaging	Het
Rgs10	A	C	7: 127,975,729 (GRCm39)	F146C	probably damaging	Het
Rimbp2	G	A	5: 128,874,875 (GRCm39)	P239S	probably damaging	Het
Rp1	A	G	1: 4,112,255 (GRCm39)	Y1199H	unknown	Het
Rrp12	A	T	19: 41,857,231 (GRCm39)	M1181K	probably benign	Het
Rundc3b	T	C	5: 8,570,982 (GRCm39)	N279S	probably benign	Het
Sbf2	G	T	7: 110,027,514 (GRCm39)	P494Q	probably damaging	Het
Scnn1b	A	G	7: 121,509,693 (GRCm39)	T281A	probably benign	Het
Scube2	A	T	7: 109,430,971 (GRCm39)	N409K	probably damaging	Het
Serpina3m	A	C	12: 104,359,008 (GRCm39)	D340A	probably damaging	Het
Sez6	G	A	11: 77,865,121 (GRCm39)	E623K	possibly damaging	Het
Sgpp2	T	C	1: 78,367,200 (GRCm39)	I111T	probably benign	Het
Shprh	C	T	10: 11,038,574 (GRCm39)	T443I	possibly damaging	Het
Sis	T	A	3: 72,799,074 (GRCm39)	Y1726F	possibly damaging	Het
Slc17a9	T	C	2: 180,374,321 (GRCm39)	L129P	probably damaging	Het
Slc1a5	T	A	7: 16,527,729 (GRCm39)	F342I	probably benign	Het
Slc4a4	T	A	5: 89,188,205 (GRCm39)		probably null	Het
Slco3a1	T	C	7: 73,952,957 (GRCm39)	E534G	possibly damaging	Het
Smok2b	A	T	17: 13,454,052 (GRCm39)	I71F	possibly damaging	Het
Tmbim7	A	T	5: 3,711,809 (GRCm39)	H18L	probably damaging	Het
Tmem151a	A	T	19: 5,131,876 (GRCm39)	Y443*	probably null	Het
Tnks1bp1	T	G	2: 84,902,125 (GRCm39)	S1674A	probably benign	Het
Trappc11	T	A	8: 47,946,348 (GRCm39)	I1095F	probably damaging	Het
Trim11	A	G	11: 58,872,864 (GRCm39)	R183G	possibly damaging	Het
Trim29	A	G	9: 43,231,797 (GRCm39)	D348G	probably benign	Het
Ttc28	A	T	5: 111,433,637 (GRCm39)	S2224C	probably damaging	Het
Vps13d	C	T	4: 144,875,915 (GRCm39)	V1537M		Het
Zfp1005	T	A	2: 150,110,305 (GRCm39)	C332S	possibly damaging	Het
Zfp184	A	G	13: 22,143,665 (GRCm39)	D457G	possibly damaging	Het

Other mutations in Nbea

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00540:Nbea	APN	3	55,535,914 (GRCm39)	missense	probably damaging	1.00
IGL00541:Nbea	APN	3	55,875,510 (GRCm39)	missense	probably benign	0.02
IGL00584:Nbea	APN	3	55,989,869 (GRCm39)	missense	probably damaging	0.98
IGL00648:Nbea	APN	3	55,916,681 (GRCm39)	missense	probably damaging	0.98
IGL00785:Nbea	APN	3	55,862,814 (GRCm39)	missense	probably benign
IGL00899:Nbea	APN	3	55,550,266 (GRCm39)	missense	probably benign	0.32
IGL00955:Nbea	APN	3	55,912,893 (GRCm39)	missense	possibly damaging	0.45
IGL01296:Nbea	APN	3	55,938,957 (GRCm39)	missense	probably benign	0.04
IGL01299:Nbea	APN	3	55,598,315 (GRCm39)	missense	probably damaging	1.00
IGL01393:Nbea	APN	3	55,912,729 (GRCm39)	missense	probably benign	0.02
IGL01550:Nbea	APN	3	55,712,669 (GRCm39)	missense	possibly damaging	0.93
IGL02023:Nbea	APN	3	55,588,437 (GRCm39)	missense	probably damaging	1.00
IGL02034:Nbea	APN	3	55,875,577 (GRCm39)	missense	probably damaging	1.00
IGL02061:Nbea	APN	3	55,625,308 (GRCm39)	missense	possibly damaging	0.54
IGL02082:Nbea	APN	3	55,875,588 (GRCm39)	missense	possibly damaging	0.88
IGL02113:Nbea	APN	3	55,899,913 (GRCm39)	missense	probably benign
IGL02188:Nbea	APN	3	55,891,258 (GRCm39)	missense	probably benign	0.00
IGL02319:Nbea	APN	3	55,893,159 (GRCm39)	missense	probably damaging	1.00
IGL02406:Nbea	APN	3	55,993,687 (GRCm39)	missense	probably benign	0.02
IGL02494:Nbea	APN	3	55,712,772 (GRCm39)	missense	probably benign	0.02
IGL02550:Nbea	APN	3	55,926,835 (GRCm39)	missense	probably damaging	0.98
IGL02706:Nbea	APN	3	55,944,699 (GRCm39)	missense	probably damaging	1.00
IGL02718:Nbea	APN	3	55,539,483 (GRCm39)	nonsense	probably null
IGL02822:Nbea	APN	3	55,926,868 (GRCm39)	missense	possibly damaging	0.93
IGL02885:Nbea	APN	3	55,539,407 (GRCm39)	missense	probably benign	0.01
IGL03000:Nbea	APN	3	55,912,048 (GRCm39)	missense	possibly damaging	0.94
IGL03081:Nbea	APN	3	55,987,339 (GRCm39)	missense	probably damaging	1.00
IGL03091:Nbea	APN	3	55,992,725 (GRCm39)	missense	probably damaging	1.00
IGL03368:Nbea	APN	3	55,987,351 (GRCm39)	missense	probably damaging	0.98
Neches	UTSW	3	55,860,455 (GRCm39)	critical splice donor site	probably null
scotland	UTSW	3	55,534,329 (GRCm39)	missense	probably damaging	1.00
Wales	UTSW	3	55,998,540 (GRCm39)	missense	probably damaging	1.00
FR4340:Nbea	UTSW	3	55,916,633 (GRCm39)	critical splice donor site	probably benign
G4846:Nbea	UTSW	3	55,994,918 (GRCm39)	missense	probably damaging	0.98
IGL02835:Nbea	UTSW	3	55,625,290 (GRCm39)	missense	possibly damaging	0.88
LCD18:Nbea	UTSW	3	55,608,948 (GRCm39)	intron	probably benign
R0087:Nbea	UTSW	3	55,998,444 (GRCm39)	missense	possibly damaging	0.92
R0220:Nbea	UTSW	3	55,912,724 (GRCm39)	missense	probably benign	0.30
R0324:Nbea	UTSW	3	55,965,369 (GRCm39)	critical splice donor site	probably null
R0330:Nbea	UTSW	3	55,550,238 (GRCm39)	missense	probably benign	0.27
R0391:Nbea	UTSW	3	55,944,698 (GRCm39)	missense	probably damaging	1.00
R0394:Nbea	UTSW	3	55,937,328 (GRCm39)	missense	probably damaging	1.00
R0419:Nbea	UTSW	3	55,726,715 (GRCm39)	missense	probably benign	0.05
R0503:Nbea	UTSW	3	55,550,257 (GRCm39)	missense	possibly damaging	0.79
R0521:Nbea	UTSW	3	55,915,689 (GRCm39)	missense	probably damaging	1.00
R0595:Nbea	UTSW	3	55,535,917 (GRCm39)	missense	probably benign	0.18
R0894:Nbea	UTSW	3	55,916,761 (GRCm39)	missense	possibly damaging	0.89
R1072:Nbea	UTSW	3	55,993,617 (GRCm39)	missense	possibly damaging	0.94
R1125:Nbea	UTSW	3	55,764,427 (GRCm39)	nonsense	probably null
R1169:Nbea	UTSW	3	55,875,744 (GRCm39)	missense	probably benign	0.00
R1241:Nbea	UTSW	3	55,965,461 (GRCm39)	missense	probably damaging	1.00
R1269:Nbea	UTSW	3	55,912,202 (GRCm39)	missense	probably benign	0.05
R1406:Nbea	UTSW	3	55,944,702 (GRCm39)	missense	probably benign	0.00
R1406:Nbea	UTSW	3	55,944,702 (GRCm39)	missense	probably benign	0.00
R1457:Nbea	UTSW	3	55,992,748 (GRCm39)	missense	probably damaging	1.00
R1482:Nbea	UTSW	3	55,987,414 (GRCm39)	missense	probably damaging	1.00
R1483:Nbea	UTSW	3	55,910,211 (GRCm39)	missense	probably benign	0.25
R1502:Nbea	UTSW	3	55,912,310 (GRCm39)	missense	probably benign	0.03
R1544:Nbea	UTSW	3	55,966,248 (GRCm39)	missense	probably damaging	0.99
R1629:Nbea	UTSW	3	55,910,312 (GRCm39)	missense	possibly damaging	0.52
R1647:Nbea	UTSW	3	55,537,650 (GRCm39)	missense	probably damaging	0.97
R1663:Nbea	UTSW	3	55,553,407 (GRCm39)	missense	possibly damaging	0.95
R1722:Nbea	UTSW	3	55,573,116 (GRCm39)	missense	probably damaging	1.00
R1757:Nbea	UTSW	3	55,537,610 (GRCm39)	missense	possibly damaging	0.83
R1771:Nbea	UTSW	3	55,841,940 (GRCm39)	missense	probably benign	0.00
R1796:Nbea	UTSW	3	55,551,129 (GRCm39)	missense	possibly damaging	0.48
R1844:Nbea	UTSW	3	55,989,857 (GRCm39)	missense	probably damaging	0.97
R1872:Nbea	UTSW	3	55,550,310 (GRCm39)	missense	probably benign	0.12
R1938:Nbea	UTSW	3	55,992,743 (GRCm39)	missense	probably damaging	1.00
R1940:Nbea	UTSW	3	55,860,521 (GRCm39)	missense	possibly damaging	0.78
R2062:Nbea	UTSW	3	55,993,578 (GRCm39)	splice site	probably benign
R2066:Nbea	UTSW	3	55,875,567 (GRCm39)	missense	probably damaging	1.00
R2097:Nbea	UTSW	3	55,630,638 (GRCm39)	missense	probably damaging	0.96
R2181:Nbea	UTSW	3	55,937,360 (GRCm39)	missense	possibly damaging	0.92
R2274:Nbea	UTSW	3	55,895,506 (GRCm39)	splice site	probably null
R2345:Nbea	UTSW	3	55,992,700 (GRCm39)	missense	probably damaging	1.00
R2423:Nbea	UTSW	3	55,992,727 (GRCm39)	missense	probably damaging	1.00
R2434:Nbea	UTSW	3	55,554,881 (GRCm39)	missense	possibly damaging	0.91
R2880:Nbea	UTSW	3	55,554,779 (GRCm39)	missense	probably benign	0.04
R2881:Nbea	UTSW	3	55,554,779 (GRCm39)	missense	probably benign	0.04
R2940:Nbea	UTSW	3	55,842,045 (GRCm39)	missense	probably benign	0.24
R3500:Nbea	UTSW	3	55,588,431 (GRCm39)	missense	possibly damaging	0.88
R3765:Nbea	UTSW	3	55,912,970 (GRCm39)	missense	probably damaging	1.00
R3790:Nbea	UTSW	3	55,912,450 (GRCm39)	missense	probably benign
R3808:Nbea	UTSW	3	55,625,269 (GRCm39)	missense	probably benign	0.02
R3845:Nbea	UTSW	3	55,993,713 (GRCm39)	splice site	probably benign
R4182:Nbea	UTSW	3	55,915,848 (GRCm39)	missense	probably damaging	0.99
R4385:Nbea	UTSW	3	55,908,059 (GRCm39)	missense	possibly damaging	0.77
R4419:Nbea	UTSW	3	55,917,021 (GRCm39)	missense	probably damaging	1.00
R4426:Nbea	UTSW	3	55,989,800 (GRCm39)	missense	probably damaging	0.98
R4451:Nbea	UTSW	3	55,899,753 (GRCm39)	critical splice donor site	probably null
R4456:Nbea	UTSW	3	55,551,205 (GRCm39)	missense	probably benign	0.00
R4604:Nbea	UTSW	3	55,631,069 (GRCm39)	missense	probably benign	0.18
R4687:Nbea	UTSW	3	55,965,486 (GRCm39)	missense	probably damaging	1.00
R4758:Nbea	UTSW	3	55,912,824 (GRCm39)	missense	probably benign
R4840:Nbea	UTSW	3	55,618,091 (GRCm39)	missense	probably benign	0.37
R4888:Nbea	UTSW	3	55,912,776 (GRCm39)	missense	possibly damaging	0.61
R4954:Nbea	UTSW	3	55,943,379 (GRCm39)	missense	probably damaging	1.00
R4972:Nbea	UTSW	3	55,992,667 (GRCm39)	missense	probably damaging	0.99
R4980:Nbea	UTSW	3	55,860,466 (GRCm39)	missense	probably benign	0.00
R4980:Nbea	UTSW	3	55,554,772 (GRCm39)	splice site	probably null
R5104:Nbea	UTSW	3	55,987,348 (GRCm39)	missense	probably damaging	1.00
R5139:Nbea	UTSW	3	55,534,384 (GRCm39)	missense	possibly damaging	0.90
R5166:Nbea	UTSW	3	55,926,874 (GRCm39)	missense	probably damaging	1.00
R5347:Nbea	UTSW	3	55,948,297 (GRCm39)	missense	probably damaging	1.00
R5350:Nbea	UTSW	3	55,926,845 (GRCm39)	missense	probably damaging	1.00
R5418:Nbea	UTSW	3	55,553,410 (GRCm39)	missense	possibly damaging	0.86
R5586:Nbea	UTSW	3	55,539,392 (GRCm39)	missense	probably benign	0.08
R5627:Nbea	UTSW	3	55,899,766 (GRCm39)	missense	probably damaging	1.00
R5683:Nbea	UTSW	3	55,536,007 (GRCm39)	missense	possibly damaging	0.53
R5765:Nbea	UTSW	3	55,912,719 (GRCm39)	missense	probably benign	0.15
R5853:Nbea	UTSW	3	55,899,822 (GRCm39)	missense	probably damaging	1.00
R5858:Nbea	UTSW	3	55,860,455 (GRCm39)	critical splice donor site	probably null
R5955:Nbea	UTSW	3	55,588,404 (GRCm39)	missense	probably benign	0.00
R5976:Nbea	UTSW	3	55,761,268 (GRCm39)	missense	probably benign	0.30
R6039:Nbea	UTSW	3	55,912,538 (GRCm39)	missense	probably benign	0.00
R6039:Nbea	UTSW	3	55,912,538 (GRCm39)	missense	probably benign	0.00
R6043:Nbea	UTSW	3	55,693,896 (GRCm39)	missense	probably benign	0.32
R6122:Nbea	UTSW	3	55,937,317 (GRCm39)	missense	probably damaging	1.00
R6218:Nbea	UTSW	3	55,535,905 (GRCm39)	missense	probably damaging	0.97
R6331:Nbea	UTSW	3	55,908,037 (GRCm39)	missense	possibly damaging	0.94
R6334:Nbea	UTSW	3	55,944,570 (GRCm39)	missense	probably damaging	1.00
R6393:Nbea	UTSW	3	55,998,540 (GRCm39)	missense	probably damaging	1.00
R6411:Nbea	UTSW	3	55,712,778 (GRCm39)	missense	probably benign	0.01
R6457:Nbea	UTSW	3	55,907,990 (GRCm39)	missense	probably damaging	1.00
R6476:Nbea	UTSW	3	55,912,227 (GRCm39)	missense	probably benign	0.00
R6488:Nbea	UTSW	3	55,625,264 (GRCm39)	missense	probably damaging	0.99
R6700:Nbea	UTSW	3	55,989,869 (GRCm39)	missense	possibly damaging	0.89
R6702:Nbea	UTSW	3	55,912,923 (GRCm39)	missense	probably benign	0.06
R6752:Nbea	UTSW	3	55,944,640 (GRCm39)	missense	probably benign
R6752:Nbea	UTSW	3	55,875,730 (GRCm39)	missense	probably benign	0.02
R6804:Nbea	UTSW	3	55,994,874 (GRCm39)	missense	probably benign	0.37
R6901:Nbea	UTSW	3	55,926,836 (GRCm39)	missense	probably damaging	1.00
R6933:Nbea	UTSW	3	55,631,031 (GRCm39)	missense	possibly damaging	0.63
R7124:Nbea	UTSW	3	55,899,865 (GRCm39)	missense	probably damaging	1.00
R7211:Nbea	UTSW	3	55,912,322 (GRCm39)	missense	probably benign	0.05
R7308:Nbea	UTSW	3	55,998,452 (GRCm39)	missense	probably damaging	1.00
R7405:Nbea	UTSW	3	55,712,687 (GRCm39)	missense	possibly damaging	0.94
R7669:Nbea	UTSW	3	55,625,200 (GRCm39)	missense	probably damaging	1.00
R7762:Nbea	UTSW	3	55,557,126 (GRCm39)	missense	probably damaging	1.00
R7833:Nbea	UTSW	3	55,910,218 (GRCm39)	missense	probably damaging	1.00
R7885:Nbea	UTSW	3	55,573,110 (GRCm39)	missense	probably damaging	0.97
R7935:Nbea	UTSW	3	55,966,086 (GRCm39)	missense	probably damaging	1.00
R8050:Nbea	UTSW	3	55,895,402 (GRCm39)	missense	probably damaging	0.99
R8108:Nbea	UTSW	3	55,726,736 (GRCm39)	missense	probably benign	0.11
R8290:Nbea	UTSW	3	55,966,056 (GRCm39)	nonsense	probably null
R8314:Nbea	UTSW	3	55,916,672 (GRCm39)	missense	probably damaging	0.99
R8321:Nbea	UTSW	3	56,090,518 (GRCm39)	missense	possibly damaging	0.86
R8376:Nbea	UTSW	3	55,551,076 (GRCm39)	missense	possibly damaging	0.79
R8410:Nbea	UTSW	3	55,944,684 (GRCm39)	missense	probably damaging	1.00
R8556:Nbea	UTSW	3	55,554,807 (GRCm39)	missense	probably benign	0.25
R8753:Nbea	UTSW	3	55,534,329 (GRCm39)	missense	probably damaging	1.00
R8844:Nbea	UTSW	3	55,998,415 (GRCm39)	missense	probably damaging	0.97
R8884:Nbea	UTSW	3	55,712,720 (GRCm39)	missense	probably benign	0.00
R8886:Nbea	UTSW	3	55,966,148 (GRCm39)	missense	probably damaging	1.00
R8890:Nbea	UTSW	3	55,926,784 (GRCm39)	splice site	probably benign
R9004:Nbea	UTSW	3	55,910,359 (GRCm39)	missense	probably benign	0.01
R9022:Nbea	UTSW	3	55,551,110 (GRCm39)	missense	possibly damaging	0.79
R9080:Nbea	UTSW	3	55,912,516 (GRCm39)	nonsense	probably null
R9087:Nbea	UTSW	3	55,550,157 (GRCm39)	critical splice donor site	probably null
R9104:Nbea	UTSW	3	55,862,809 (GRCm39)	missense	probably benign
R9165:Nbea	UTSW	3	55,912,289 (GRCm39)	missense	probably benign	0.15
R9219:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9221:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9222:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9260:Nbea	UTSW	3	55,891,233 (GRCm39)	missense	possibly damaging	0.50
R9263:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9265:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9294:Nbea	UTSW	3	55,998,513 (GRCm39)	missense	probably benign	0.00
R9360:Nbea	UTSW	3	55,943,319 (GRCm39)	missense	possibly damaging	0.96
R9387:Nbea	UTSW	3	55,898,460 (GRCm39)	missense	probably benign	0.12
R9428:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9435:Nbea	UTSW	3	55,943,309 (GRCm39)	missense	possibly damaging	0.63
R9507:Nbea	UTSW	3	55,573,011 (GRCm39)	missense	probably damaging	1.00
R9514:Nbea	UTSW	3	55,937,366 (GRCm39)	missense	probably damaging	1.00
R9516:Nbea	UTSW	3	55,937,366 (GRCm39)	missense	probably damaging	1.00
R9674:Nbea	UTSW	3	55,966,183 (GRCm39)	missense	probably damaging	1.00
R9688:Nbea	UTSW	3	55,557,165 (GRCm39)	missense	probably benign	0.42
RF051:Nbea	UTSW	3	55,916,633 (GRCm39)	critical splice donor site	probably benign
X0018:Nbea	UTSW	3	55,943,469 (GRCm39)	missense	probably benign	0.39
Z1088:Nbea	UTSW	3	55,630,584 (GRCm39)	missense	probably benign	0.34
Z1177:Nbea	UTSW	3	55,938,971 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AACTACTCATTTGCACATGCTC -3'
(R):5'- ATCAGGCCATACCCTCTGAG -3'

Sequencing Primer
(F):5'- TGCACATGCTCTCTTAATACAGG -3'
(R):5'- CCTCTGAGAGGGAGTTTGGAAG -3'

Posted On

2022-10-06