Mutagenetix > Incidental Mutation

Incidental Mutation 'R9711:Tenm2'

730180

Institutional Source

Beutler Lab

Gene Symbol

Tenm2

Ensembl Gene

ENSMUSG00000049336

Gene Name

teneurin transmembrane protein 2

Synonyms

D3Bwg1534e, Odz2, 9330187F13Rik, Ten-m2, 2610040L17Rik

MMRRC Submission

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.569) question?

Stock #

R9711 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

35897483-37126791 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to A at 35915341 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Asparagine at position 2065 (K2065N)

Ref Sequence

ENSEMBL: ENSMUSP00000052014 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057207] [ENSMUST00000102801] [ENSMUST00000163524]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000057207
AA Change: K2065N

PolyPhen 2 Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000052014
Gene: ENSMUSG00000049336
AA Change: K2065N

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	374	4.9e-177	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	738	766	9.63e0	SMART
EGF	769	797	1.25e1	SMART
EGF	800	832	1.4e0	SMART
low complexity region	1459	1475	N/A	INTRINSIC
low complexity region	2219	2230	N/A	INTRINSIC
Pfam:Tox-GHH	2681	2758	1.4e-34	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000102801
AA Change: K2064N

PolyPhen 2 Score 0.958 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000099865
Gene: ENSMUSG00000049336
AA Change: K2064N

Domain	Start	End	E-Value	Type
Pfam:Ten_N	9	374	2e-186	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	737	765	9.63e0	SMART
EGF	768	796	1.25e1	SMART
EGF	799	831	1.4e0	SMART
low complexity region	1458	1474	N/A	INTRINSIC
low complexity region	2218	2229	N/A	INTRINSIC
Pfam:Tox-GHH	2679	2757	2e-34	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000163524
AA Change: K2064N

PolyPhen 2 Score 0.958 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000129951
Gene: ENSMUSG00000049336
AA Change: K2064N

Domain	Start	End	E-Value	Type
Pfam:Ten_N	9	374	2e-186	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	737	765	9.63e0	SMART
EGF	768	796	1.25e1	SMART
EGF	799	831	1.4e0	SMART
low complexity region	1458	1474	N/A	INTRINSIC
low complexity region	2218	2229	N/A	INTRINSIC
Pfam:Tox-GHH	2679	2757	2e-34	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.0%

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozygous for a null allele show abnormalities in the laterality and mapping of ipsilateral retinal projections that lead to loss of ipsilateral drive, defects in binocular vision, and impaired performance on a visual discrimination task. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 87 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc12	T	C	8: 87,275,388 (GRCm39)	D430G	probably damaging	Het
Adgrf1	T	C	17: 43,621,580 (GRCm39)	S606P	possibly damaging	Het
Afap1	A	G	5: 36,141,540 (GRCm39)	N475D	probably damaging	Het
Ahnak2	A	G	12: 112,739,468 (GRCm39)	S1535P	possibly damaging	Het
Akt1	G	T	12: 112,624,885 (GRCm39)	H194N	possibly damaging	Het
Api5	T	A	2: 94,251,812 (GRCm39)	Q396L	possibly damaging	Het
Aplp2	T	C	9: 31,083,303 (GRCm39)	N148S	probably benign	Het
Asb3	A	G	11: 31,031,400 (GRCm39)	Y340C	probably damaging	Het
Bbox1	A	T	2: 110,098,581 (GRCm39)	M332K	probably damaging	Het
Cabin1	A	T	10: 75,579,090 (GRCm39)	S449T	probably benign	Het
Carns1	A	G	19: 4,216,007 (GRCm39)	V725A	possibly damaging	Het
Cdkn1b	A	G	6: 134,898,058 (GRCm39)	K59R	possibly damaging	Het
Cdv3	A	T	9: 103,233,539 (GRCm39)	I212K	probably damaging	Het
Clec14a	T	A	12: 58,314,432 (GRCm39)	I397F	probably damaging	Het
Cnnm1	A	G	19: 43,483,469 (GRCm39)	I950V	possibly damaging	Het
Ddi2	A	G	4: 141,422,734 (GRCm39)	M326T	probably benign	Het
Dhx30	T	C	9: 109,914,103 (GRCm39)	T1065A	probably benign	Het
Eif3c	A	T	7: 126,146,674 (GRCm39)	M808K	possibly damaging	Het
Evi2	G	T	11: 79,406,971 (GRCm39)	H201Q	possibly damaging	Het
Exoc4	A	G	6: 33,452,991 (GRCm39)	T494A	unknown	Het
Fam83f	T	A	15: 80,574,819 (GRCm39)	M242K	probably damaging	Het
Fat4	T	C	3: 39,055,374 (GRCm39)	Y4198H	probably benign	Het
Fcgbp	C	A	7: 27,793,000 (GRCm39)	N1001K	probably benign	Het
Gda	G	T	19: 21,400,449 (GRCm39)	A164E	probably damaging	Het
Gm19410	T	C	8: 36,279,493 (GRCm39)	V1786A	possibly damaging	Het
Gm45871	A	G	18: 90,609,069 (GRCm39)	N82S	probably benign	Het
Gnas	T	A	2: 174,141,392 (GRCm39)	S580T	unknown	Het
Gprin1	G	A	13: 54,886,714 (GRCm39)	P520L	probably benign	Het
Gramd4	C	T	15: 86,014,751 (GRCm39)	R433C	probably damaging	Het
Ighv5-12	T	A	12: 113,665,958 (GRCm39)	T47S	probably benign	Het
Itprid1	T	G	6: 55,864,018 (GRCm39)	S115A	probably damaging	Het
Kdm5a	T	A	6: 120,367,658 (GRCm39)	L451Q	probably damaging	Het
Kif12	T	A	4: 63,084,126 (GRCm39)	R624S	probably benign	Het
Lepr	T	A	4: 101,592,851 (GRCm39)	Y155*	probably null	Het
Lnx2	T	A	5: 146,961,376 (GRCm39)	I519F	probably damaging	Het
Marchf7	T	A	2: 60,060,175 (GRCm39)	S101T	probably damaging	Het
Miox	A	G	15: 89,220,785 (GRCm39)	D230G	probably damaging	Het
Morc2a	T	A	11: 3,600,381 (GRCm39)	M1K	probably null	Het
Mtus1	T	C	8: 41,536,222 (GRCm39)	N498S	probably damaging	Het
Mxd1	T	A	6: 86,645,554 (GRCm39)	R46W	probably damaging	Het
Ndufa11	G	C	17: 57,024,843 (GRCm39)	A2P	possibly damaging	Het
Necab2	C	T	8: 120,198,513 (GRCm39)	H362Y	probably damaging	Het
Nphp4	G	A	4: 152,623,434 (GRCm39)	V703I	possibly damaging	Het
Nup54	T	C	5: 92,582,218 (GRCm39)	N31S	unknown	Het
Or13a23-ps1	T	A	7: 140,118,497 (GRCm39)	S22R	probably benign	Het
Or1ad6	T	C	11: 50,860,316 (GRCm39)	L157P	probably damaging	Het
Or1e34	A	T	11: 73,778,696 (GRCm39)	C167*	probably null	Het
Or8b4	A	C	9: 37,830,066 (GRCm39)	T38P	probably damaging	Het
P2rx2	T	C	5: 110,490,388 (GRCm39)	E109G	possibly damaging	Het
Pcdha7	T	C	18: 37,107,409 (GRCm39)	S145P	probably damaging	Het
Pdlim5	A	T	3: 141,948,529 (GRCm39)	V586E	probably damaging	Het
Pex5l	T	C	3: 33,136,204 (GRCm39)	E5G	probably benign	Het
Plch1	T	A	3: 63,615,176 (GRCm39)	D774V	probably damaging	Het
Plekhg3	A	T	12: 76,611,726 (GRCm39)	D335V	possibly damaging	Het
Pop1	A	G	15: 34,530,227 (GRCm39)	H905R	probably benign	Het
Ppm1k	T	C	6: 57,492,720 (GRCm39)	T189A	probably damaging	Het
Pramel13	A	G	4: 144,122,517 (GRCm39)	L9P	probably damaging	Het
Recql5	A	G	11: 115,784,367 (GRCm39)	V911A	probably damaging	Het
Rnf145	T	A	11: 44,415,830 (GRCm39)	L15*	probably null	Het
Rpl13a	A	G	7: 44,776,673 (GRCm39)	V29A	probably benign	Het
Rps6ka5	A	G	12: 100,540,250 (GRCm39)	V491A	probably benign	Het
Setbp1	T	C	18: 78,900,142 (GRCm39)	H1175R	probably benign	Het
Setd5	T	C	6: 113,093,063 (GRCm39)	S372P	probably damaging	Het
Slc1a3	T	C	15: 8,675,177 (GRCm39)	E276G	probably damaging	Het
Slc36a2	T	C	11: 55,070,169 (GRCm39)	N136S	probably benign	Het
Spag1	G	A	15: 36,190,683 (GRCm39)		probably null	Het
Spon1	A	C	7: 113,387,685 (GRCm39)	T81P	probably damaging	Het
Sv2b	A	T	7: 74,856,238 (GRCm39)	D17E	probably benign	Het
Tasor2	A	G	13: 3,649,667 (GRCm39)	V44A	probably benign	Het
Tax1bp1	C	T	6: 52,704,215 (GRCm39)	T65I	probably damaging	Het
Ticam2	T	C	18: 46,693,658 (GRCm39)	D143G	probably damaging	Het
Tmem132d	T	C	5: 127,869,579 (GRCm39)	E585G	possibly damaging	Het
Tnfrsf8	C	T	4: 145,019,668 (GRCm39)		probably null	Het
Trim44	C	T	2: 102,230,813 (GRCm39)	G73R	unknown	Het
Trpc3	C	T	3: 36,692,713 (GRCm39)	D760N	possibly damaging	Het
Tspan9	T	A	6: 127,942,715 (GRCm39)	M171L	probably benign	Het
Ugt2b37	A	G	5: 87,402,532 (GRCm39)	F33S	possibly damaging	Het
Vav2	A	T	2: 27,159,027 (GRCm39)	V734E	probably damaging	Het
Vmn1r214	A	G	13: 23,218,508 (GRCm39)	M1V	probably null	Het
Vmn1r24	A	T	6: 57,932,804 (GRCm39)	V238E	probably damaging	Het
Vmn2r107	A	G	17: 20,577,262 (GRCm39)	Q420R	probably damaging	Het
Vmn2r31	G	A	7: 7,387,085 (GRCm39)	P829S	probably damaging	Het
Xpo6	A	G	7: 125,712,873 (GRCm39)	F703L	probably benign	Het
Zfp442	T	A	2: 150,250,207 (GRCm39)	H565L	possibly damaging	Het
Zfp950	A	T	19: 61,116,000 (GRCm39)	D2E	probably damaging	Het
Zfp992	T	A	4: 146,551,345 (GRCm39)	S355R	probably damaging	Het
Zwilch	A	T	9: 64,063,303 (GRCm39)	F309Y	probably damaging	Het

Other mutations in Tenm2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00161:Tenm2	APN	11	36,097,726 (GRCm39)	splice site	probably benign
IGL00834:Tenm2	APN	11	35,915,085 (GRCm39)	missense	probably damaging	1.00
IGL00911:Tenm2	APN	11	35,899,560 (GRCm39)	nonsense	probably null
IGL00937:Tenm2	APN	11	35,915,450 (GRCm39)	missense	probably damaging	1.00
IGL01154:Tenm2	APN	11	35,932,371 (GRCm39)	missense	probably damaging	1.00
IGL01313:Tenm2	APN	11	35,915,075 (GRCm39)	missense	probably damaging	0.98
IGL01346:Tenm2	APN	11	35,918,232 (GRCm39)	nonsense	probably null
IGL01539:Tenm2	APN	11	35,997,654 (GRCm39)	missense	possibly damaging	0.89
IGL01629:Tenm2	APN	11	36,755,711 (GRCm39)	missense	probably damaging	0.98
IGL01780:Tenm2	APN	11	35,937,768 (GRCm39)	missense	probably benign
IGL01821:Tenm2	APN	11	35,914,710 (GRCm39)	missense	probably damaging	0.98
IGL01988:Tenm2	APN	11	35,918,078 (GRCm39)	missense	probably damaging	1.00
IGL02002:Tenm2	APN	11	36,097,922 (GRCm39)	missense	probably benign
IGL02449:Tenm2	APN	11	35,914,449 (GRCm39)	missense	probably damaging	0.99
IGL02505:Tenm2	APN	11	35,942,743 (GRCm39)	nonsense	probably null
IGL02649:Tenm2	APN	11	36,097,912 (GRCm39)	missense	possibly damaging	0.85
IGL02688:Tenm2	APN	11	35,959,285 (GRCm39)	missense	probably benign	0.05
IGL02801:Tenm2	APN	11	35,937,857 (GRCm39)	nonsense	probably null
IGL02928:Tenm2	APN	11	35,917,997 (GRCm39)	missense	possibly damaging	0.69
IGL02940:Tenm2	APN	11	35,932,471 (GRCm39)	missense	probably damaging	1.00
IGL03202:Tenm2	APN	11	35,915,375 (GRCm39)	missense	probably damaging	1.00
IGL03213:Tenm2	APN	11	35,914,157 (GRCm39)	missense	probably benign	0.05
IGL03276:Tenm2	APN	11	35,963,603 (GRCm39)	missense	possibly damaging	0.95
IGL03296:Tenm2	APN	11	35,942,852 (GRCm39)	splice site	probably null
IGL03381:Tenm2	APN	11	35,959,238 (GRCm39)	missense	probably benign	0.01
IGL03398:Tenm2	APN	11	35,915,370 (GRCm39)	missense	probably damaging	1.00
browser	UTSW	11	35,937,592 (GRCm39)	critical splice donor site	probably null
mosaic	UTSW	11	35,954,602 (GRCm39)	critical splice donor site	probably null
IGL02799:Tenm2	UTSW	11	36,164,235 (GRCm39)	missense	probably damaging	1.00
PIT4260001:Tenm2	UTSW	11	36,054,557 (GRCm39)	missense	probably damaging	1.00
PIT4382001:Tenm2	UTSW	11	35,954,729 (GRCm39)	missense	probably damaging	0.99
R0004:Tenm2	UTSW	11	35,914,184 (GRCm39)	missense	probably damaging	1.00
R0420:Tenm2	UTSW	11	36,097,951 (GRCm39)	splice site	probably benign
R0537:Tenm2	UTSW	11	36,054,557 (GRCm39)	missense	probably damaging	1.00
R0599:Tenm2	UTSW	11	35,915,607 (GRCm39)	missense	possibly damaging	0.93
R0636:Tenm2	UTSW	11	36,834,803 (GRCm39)	missense	probably damaging	1.00
R0693:Tenm2	UTSW	11	35,915,636 (GRCm39)	missense	probably damaging	1.00
R0991:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R0992:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1167:Tenm2	UTSW	11	36,755,511 (GRCm39)	missense	probably benign	0.30
R1177:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1178:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1179:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1180:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1181:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1193:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1194:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1259:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1265:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1267:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1268:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1269:Tenm2	UTSW	11	35,899,185 (GRCm39)	missense	possibly damaging	0.64
R1270:Tenm2	UTSW	11	35,932,486 (GRCm39)	missense	probably damaging	1.00
R1272:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1273:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1311:Tenm2	UTSW	11	35,959,421 (GRCm39)	splice site	probably benign
R1374:Tenm2	UTSW	11	35,899,281 (GRCm39)	missense	probably benign	0.00
R1542:Tenm2	UTSW	11	36,191,047 (GRCm39)	missense	probably damaging	0.99
R1573:Tenm2	UTSW	11	35,937,896 (GRCm39)	missense	probably damaging	1.00
R1579:Tenm2	UTSW	11	35,997,610 (GRCm39)	missense	probably damaging	1.00
R1697:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1722:Tenm2	UTSW	11	35,898,930 (GRCm39)	missense	probably damaging	1.00
R1756:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1793:Tenm2	UTSW	11	35,914,209 (GRCm39)	missense	probably damaging	0.99
R1950:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1954:Tenm2	UTSW	11	35,938,374 (GRCm39)	missense	possibly damaging	0.87
R2025:Tenm2	UTSW	11	35,938,091 (GRCm39)	nonsense	probably null
R2117:Tenm2	UTSW	11	35,915,681 (GRCm39)	missense	probably damaging	1.00
R2244:Tenm2	UTSW	11	36,755,689 (GRCm39)	missense	probably damaging	0.98
R2298:Tenm2	UTSW	11	35,937,604 (GRCm39)	missense	possibly damaging	0.62
R2432:Tenm2	UTSW	11	35,918,018 (GRCm39)	missense	probably damaging	1.00
R3014:Tenm2	UTSW	11	35,914,800 (GRCm39)	missense	probably damaging	1.00
R3115:Tenm2	UTSW	11	35,914,193 (GRCm39)	missense	probably damaging	1.00
R3684:Tenm2	UTSW	11	35,942,644 (GRCm39)	missense	probably benign	0.00
R3685:Tenm2	UTSW	11	35,942,644 (GRCm39)	missense	probably benign	0.00
R3705:Tenm2	UTSW	11	35,959,153 (GRCm39)	missense	probably damaging	0.97
R3820:Tenm2	UTSW	11	35,915,147 (GRCm39)	missense	probably damaging	0.98
R3821:Tenm2	UTSW	11	35,915,147 (GRCm39)	missense	probably damaging	0.98
R3822:Tenm2	UTSW	11	35,915,147 (GRCm39)	missense	probably damaging	0.98
R3844:Tenm2	UTSW	11	35,938,365 (GRCm39)	missense	probably damaging	0.98
R3878:Tenm2	UTSW	11	36,030,401 (GRCm39)	critical splice donor site	probably null
R4019:Tenm2	UTSW	11	35,937,901 (GRCm39)	missense	probably benign	0.04
R4062:Tenm2	UTSW	11	35,899,482 (GRCm39)	missense	probably damaging	1.00
R4367:Tenm2	UTSW	11	35,918,225 (GRCm39)	missense	probably benign
R4395:Tenm2	UTSW	11	35,915,451 (GRCm39)	missense	probably benign	0.23
R4508:Tenm2	UTSW	11	35,899,172 (GRCm39)	missense	possibly damaging	0.82
R4534:Tenm2	UTSW	11	35,953,931 (GRCm39)	missense	possibly damaging	0.64
R4539:Tenm2	UTSW	11	35,937,607 (GRCm39)	missense	probably damaging	1.00
R4644:Tenm2	UTSW	11	35,937,963 (GRCm39)	missense	probably benign	0.00
R4661:Tenm2	UTSW	11	35,915,275 (GRCm39)	missense	probably damaging	0.99
R4669:Tenm2	UTSW	11	35,901,314 (GRCm39)	missense	probably damaging	1.00
R4687:Tenm2	UTSW	11	35,939,924 (GRCm39)	missense	probably benign
R4711:Tenm2	UTSW	11	36,191,039 (GRCm39)	missense	probably damaging	0.98
R4816:Tenm2	UTSW	11	35,918,117 (GRCm39)	missense	probably damaging	1.00
R4843:Tenm2	UTSW	11	35,914,847 (GRCm39)	missense	probably damaging	1.00
R4850:Tenm2	UTSW	11	35,914,315 (GRCm39)	nonsense	probably null
R4870:Tenm2	UTSW	11	35,969,396 (GRCm39)	missense	probably damaging	1.00
R5058:Tenm2	UTSW	11	36,097,907 (GRCm39)	missense	possibly damaging	0.80
R5071:Tenm2	UTSW	11	35,959,208 (GRCm39)	missense	probably damaging	0.99
R5073:Tenm2	UTSW	11	35,959,208 (GRCm39)	missense	probably damaging	0.99
R5074:Tenm2	UTSW	11	35,959,208 (GRCm39)	missense	probably damaging	0.99
R5081:Tenm2	UTSW	11	35,915,460 (GRCm39)	missense	possibly damaging	0.95
R5093:Tenm2	UTSW	11	36,834,989 (GRCm39)	missense	probably damaging	1.00
R5170:Tenm2	UTSW	11	35,915,633 (GRCm39)	missense	probably damaging	0.98
R5253:Tenm2	UTSW	11	35,938,028 (GRCm39)	nonsense	probably null
R5343:Tenm2	UTSW	11	35,960,330 (GRCm39)	missense	probably benign	0.00
R5493:Tenm2	UTSW	11	36,755,503 (GRCm39)	missense	probably benign	0.01
R5600:Tenm2	UTSW	11	36,054,541 (GRCm39)	splice site	probably null
R5677:Tenm2	UTSW	11	36,032,510 (GRCm39)	missense	probably damaging	0.98
R5703:Tenm2	UTSW	11	35,914,626 (GRCm39)	missense	probably benign	0.34
R5707:Tenm2	UTSW	11	35,938,009 (GRCm39)	missense	possibly damaging	0.79
R6026:Tenm2	UTSW	11	35,963,556 (GRCm39)	critical splice donor site	probably null
R6063:Tenm2	UTSW	11	36,054,544 (GRCm39)	critical splice donor site	probably null
R6086:Tenm2	UTSW	11	35,899,473 (GRCm39)	missense	possibly damaging	0.64
R6151:Tenm2	UTSW	11	35,899,610 (GRCm39)	missense	probably damaging	1.00
R6169:Tenm2	UTSW	11	36,030,517 (GRCm39)	missense	probably damaging	0.99
R6193:Tenm2	UTSW	11	35,937,621 (GRCm39)	missense	probably damaging	1.00
R6405:Tenm2	UTSW	11	36,755,686 (GRCm39)	missense	probably benign	0.44
R6477:Tenm2	UTSW	11	35,901,334 (GRCm39)	critical splice acceptor site	probably null
R6607:Tenm2	UTSW	11	35,954,602 (GRCm39)	critical splice donor site	probably null
R6668:Tenm2	UTSW	11	35,937,592 (GRCm39)	critical splice donor site	probably null
R6825:Tenm2	UTSW	11	35,937,711 (GRCm39)	missense	probably benign	0.02
R6885:Tenm2	UTSW	11	35,914,407 (GRCm39)	missense	possibly damaging	0.95
R7017:Tenm2	UTSW	11	36,062,236 (GRCm39)	missense	probably damaging	0.98
R7115:Tenm2	UTSW	11	36,054,644 (GRCm39)	missense	probably damaging	0.99
R7153:Tenm2	UTSW	11	35,915,009 (GRCm39)	missense	probably damaging	0.98
R7173:Tenm2	UTSW	11	35,932,378 (GRCm39)	missense	probably damaging	0.99
R7199:Tenm2	UTSW	11	36,062,263 (GRCm39)	missense	probably damaging	1.00
R7205:Tenm2	UTSW	11	35,939,956 (GRCm39)	missense	probably damaging	0.99
R7250:Tenm2	UTSW	11	35,963,625 (GRCm39)	missense	probably damaging	1.00
R7290:Tenm2	UTSW	11	35,914,298 (GRCm39)	missense	probably damaging	1.00
R7366:Tenm2	UTSW	11	35,960,241 (GRCm39)	missense	probably benign	0.09
R7432:Tenm2	UTSW	11	36,755,768 (GRCm39)	missense	probably benign
R7504:Tenm2	UTSW	11	36,030,570 (GRCm39)	missense	probably damaging	1.00
R7513:Tenm2	UTSW	11	35,942,727 (GRCm39)	missense	probably benign	0.34
R7523:Tenm2	UTSW	11	35,969,408 (GRCm39)	splice site	probably null
R7527:Tenm2	UTSW	11	36,097,803 (GRCm39)	missense	probably damaging	1.00
R7648:Tenm2	UTSW	11	35,997,563 (GRCm39)	missense	probably damaging	1.00
R7653:Tenm2	UTSW	11	35,938,174 (GRCm39)	missense	probably benign	0.09
R7717:Tenm2	UTSW	11	36,755,762 (GRCm39)	missense	probably damaging	0.97
R7739:Tenm2	UTSW	11	35,960,388 (GRCm39)	missense	possibly damaging	0.50
R7762:Tenm2	UTSW	11	35,914,133 (GRCm39)	missense	possibly damaging	0.74
R7786:Tenm2	UTSW	11	35,901,276 (GRCm39)	missense	probably damaging	0.99
R7803:Tenm2	UTSW	11	35,937,943 (GRCm39)	missense	probably damaging	0.98
R7834:Tenm2	UTSW	11	35,915,681 (GRCm39)	missense	probably damaging	1.00
R7838:Tenm2	UTSW	11	35,997,626 (GRCm39)	missense	probably benign	0.02
R8073:Tenm2	UTSW	11	36,030,471 (GRCm39)	missense	possibly damaging	0.56
R8076:Tenm2	UTSW	11	35,918,048 (GRCm39)	missense	probably benign	0.23
R8109:Tenm2	UTSW	11	35,899,137 (GRCm39)	missense	probably benign
R8306:Tenm2	UTSW	11	35,960,196 (GRCm39)	missense	possibly damaging	0.52
R8352:Tenm2	UTSW	11	35,914,428 (GRCm39)	missense	probably damaging	0.98
R8452:Tenm2	UTSW	11	35,914,428 (GRCm39)	missense	probably damaging	0.98
R8864:Tenm2	UTSW	11	35,918,022 (GRCm39)	missense	possibly damaging	0.95
R8880:Tenm2	UTSW	11	35,942,788 (GRCm39)	missense	probably damaging	0.99
R8943:Tenm2	UTSW	11	36,834,861 (GRCm39)	missense	probably damaging	0.98
R8969:Tenm2	UTSW	11	35,942,688 (GRCm39)	missense	probably damaging	0.99
R9168:Tenm2	UTSW	11	35,930,722 (GRCm39)	missense	probably damaging	1.00
R9279:Tenm2	UTSW	11	35,959,303 (GRCm39)	missense	probably benign	0.00
R9294:Tenm2	UTSW	11	35,915,327 (GRCm39)	missense	probably damaging	0.98
R9320:Tenm2	UTSW	11	35,914,474 (GRCm39)	missense	probably damaging	0.99
R9373:Tenm2	UTSW	11	35,930,713 (GRCm39)	missense	probably damaging	1.00
R9408:Tenm2	UTSW	11	35,960,246 (GRCm39)	missense	probably damaging	1.00
R9410:Tenm2	UTSW	11	36,032,396 (GRCm39)	missense	probably damaging	0.99
R9454:Tenm2	UTSW	11	36,112,286 (GRCm39)	missense	probably benign
R9489:Tenm2	UTSW	11	36,834,791 (GRCm39)	missense	probably damaging	0.99
RF021:Tenm2	UTSW	11	35,915,030 (GRCm39)	missense	possibly damaging	0.95
X0018:Tenm2	UTSW	11	35,915,027 (GRCm39)	missense	probably damaging	1.00
X0063:Tenm2	UTSW	11	35,915,557 (GRCm39)	missense	probably benign
Z1088:Tenm2	UTSW	11	36,164,094 (GRCm39)	missense	probably damaging	1.00
Z1177:Tenm2	UTSW	11	36,191,162 (GRCm39)	missense	probably damaging	0.98
Z1177:Tenm2	UTSW	11	35,899,061 (GRCm39)	missense	possibly damaging	0.95
Z1177:Tenm2	UTSW	11	36,275,957 (GRCm39)	missense	probably benign	0.01

Predicted Primers

PCR Primer
(F):5'- ACTTGCCGAAGTGTTCCAC -3'
(R):5'- TTGACTACAGTGATGACGGC -3'

Sequencing Primer
(F):5'- CCTTGCCGGAAATCTCATCATAG -3'
(R):5'- CTAAAGACATCTTTCTTGGGCACTGG -3'

Posted On

2022-10-06