Incidental Mutation 'R9717:Pik3c2g'
| ID |
730527 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pik3c2g
|
| Ensembl Gene |
ENSMUSG00000030228 |
| Gene Name |
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma |
| Synonyms |
|
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.105)
|
| Stock # |
R9717 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
139591070-139915010 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 139841910 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 772
(S772P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000107499
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000087657]
[ENSMUST00000111868]
[ENSMUST00000218528]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000087657
AA Change: S404P
PolyPhen 2
Score 0.474 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000084939
Gene: ENSMUSG00000030228
AA Change: S404P
| Domain | Start | End | E-Value | Type |
|---|
|
PI3Kc
|
125 |
387 |
2.11e-109 |
SMART |
|
PX
|
411 |
515 |
1.24e-21 |
SMART |
|
C2
|
550 |
647 |
1.34e-7 |
SMART |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000107499
Gene: ENSMUSG00000030228
AA Change: S772P
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1e8xa2
|
1 |
83 |
4e-16 |
SMART |
|
PI3Ka
|
103 |
288 |
7.6e-29 |
SMART |
|
PI3Kc
|
375 |
637 |
2.11e-109 |
SMART |
|
PX
|
661 |
765 |
1.24e-21 |
SMART |
|
C2
|
800 |
897 |
1.34e-7 |
SMART |
|
| Predicted Effect |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
PHENOTYPE: Mice homozygous for a knock-out allelel exhibit reduced liver glucogen accumulation, hyperlipidemia, adiposity and insulin resistance with age or after consumption of a high-fat diet. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adgrv1 |
T |
A |
13: 81,668,900 (GRCm39) |
N2552I |
probably damaging |
Het |
| Amph |
G |
T |
13: 19,309,253 (GRCm39) |
A444S |
probably benign |
Het |
| Ankrd52 |
A |
G |
10: 128,216,457 (GRCm39) |
N157S |
probably benign |
Het |
| Arhgap29 |
T |
C |
3: 121,797,920 (GRCm39) |
F537L |
probably benign |
Het |
| Asic1 |
A |
C |
15: 99,590,657 (GRCm39) |
T136P |
probably damaging |
Het |
| Atg2b |
T |
C |
12: 105,605,561 (GRCm39) |
Y1468C |
probably benign |
Het |
| Atm |
A |
G |
9: 53,427,817 (GRCm39) |
L431P |
probably damaging |
Het |
| Atosb |
T |
C |
4: 43,036,050 (GRCm39) |
H227R |
probably damaging |
Het |
| Btaf1 |
A |
G |
19: 36,922,646 (GRCm39) |
T17A |
probably benign |
Het |
| Car10 |
A |
G |
11: 93,195,367 (GRCm39) |
N58S |
probably benign |
Het |
| Cd79b |
A |
T |
11: 106,202,845 (GRCm39) |
D252E |
probably damaging |
Het |
| Cdipt |
C |
T |
7: 126,576,202 (GRCm39) |
|
probably benign |
Het |
| Cebpe |
T |
C |
14: 54,949,165 (GRCm39) |
D84G |
probably damaging |
Het |
| Cenpj |
T |
C |
14: 56,790,453 (GRCm39) |
E532G |
probably benign |
Het |
| Cherp |
A |
G |
8: 73,216,920 (GRCm39) |
|
probably null |
Het |
| Chuk |
T |
C |
19: 44,071,109 (GRCm39) |
D532G |
possibly damaging |
Het |
| Clec1b |
C |
T |
6: 129,374,603 (GRCm39) |
T9I |
probably benign |
Het |
| Clspn |
G |
T |
4: 126,458,756 (GRCm39) |
A280S |
possibly damaging |
Het |
| Cts3 |
T |
G |
13: 61,712,799 (GRCm39) |
Y307S |
probably benign |
Het |
| Cyp2c39 |
T |
C |
19: 39,556,493 (GRCm39) |
M443T |
possibly damaging |
Het |
| Dhx57 |
C |
T |
17: 80,582,447 (GRCm39) |
R386H |
probably damaging |
Het |
| Dhx58 |
A |
T |
11: 100,592,133 (GRCm39) |
M305K |
probably benign |
Het |
| Dlgap3 |
T |
C |
4: 127,129,287 (GRCm39) |
L894P |
probably damaging |
Het |
| Dnah3 |
A |
T |
7: 119,574,299 (GRCm39) |
N2164K |
probably damaging |
Het |
| Dnajb14 |
A |
G |
3: 137,608,044 (GRCm39) |
N183S |
probably benign |
Het |
| Drd5 |
G |
T |
5: 38,478,090 (GRCm39) |
R361L |
probably damaging |
Het |
| Duoxa1 |
T |
C |
2: 122,135,622 (GRCm39) |
E159G |
probably damaging |
Het |
| Exoc1 |
T |
A |
5: 76,711,079 (GRCm39) |
S659R |
probably benign |
Het |
| Fbln7 |
T |
C |
2: 128,719,314 (GRCm39) |
I37T |
probably benign |
Het |
| Fcgrt |
T |
G |
7: 44,744,853 (GRCm39) |
E205A |
possibly damaging |
Het |
| Fcho2 |
A |
T |
13: 98,900,202 (GRCm39) |
S304T |
probably damaging |
Het |
| Gbp9 |
C |
A |
5: 105,253,587 (GRCm39) |
G43* |
probably null |
Het |
| Gucy2d |
A |
G |
7: 98,123,868 (GRCm39) |
K151R |
probably benign |
Het |
| Heatr4 |
T |
A |
12: 84,024,829 (GRCm39) |
I331F |
probably damaging |
Het |
| Hmcn1 |
G |
A |
1: 150,485,378 (GRCm39) |
T4408I |
probably damaging |
Het |
| Hoxc9 |
C |
T |
15: 102,890,551 (GRCm39) |
T156M |
probably benign |
Het |
| Hrnr |
A |
T |
3: 93,227,987 (GRCm39) |
E35V |
probably damaging |
Het |
| Idua |
C |
T |
5: 108,818,037 (GRCm39) |
Q70* |
probably null |
Het |
| Klf5 |
A |
T |
14: 99,539,189 (GRCm39) |
I201F |
probably damaging |
Het |
| Lonrf1 |
T |
C |
8: 36,701,164 (GRCm39) |
K349E |
probably damaging |
Het |
| Lrp1b |
A |
T |
2: 41,158,395 (GRCm39) |
D1721E |
|
Het |
| Mdh1 |
T |
A |
11: 21,521,870 (GRCm39) |
|
probably benign |
Het |
| Mllt11 |
T |
C |
3: 95,127,521 (GRCm39) |
H83R |
probably benign |
Het |
| Mrgprb4 |
A |
C |
7: 47,848,583 (GRCm39) |
I115S |
possibly damaging |
Het |
| Mrpl38 |
A |
G |
11: 116,023,296 (GRCm39) |
F319S |
probably damaging |
Het |
| Naif1 |
A |
T |
2: 32,344,907 (GRCm39) |
M204L |
probably benign |
Het |
| Ncan |
T |
A |
8: 70,554,628 (GRCm39) |
D1063V |
probably damaging |
Het |
| Noto |
A |
T |
6: 85,401,327 (GRCm39) |
R119W |
possibly damaging |
Het |
| Or4c115 |
G |
A |
2: 88,927,573 (GRCm39) |
L233F |
probably benign |
Het |
| Or51h7 |
A |
T |
7: 102,591,165 (GRCm39) |
D206E |
probably damaging |
Het |
| Or6c69 |
T |
A |
10: 129,748,048 (GRCm39) |
Y33F |
probably damaging |
Het |
| Or8b3 |
A |
T |
9: 38,314,841 (GRCm39) |
I224F |
probably damaging |
Het |
| Ovch2 |
A |
G |
7: 107,393,584 (GRCm39) |
W181R |
probably damaging |
Het |
| Palm |
G |
C |
10: 79,655,117 (GRCm39) |
G292R |
probably damaging |
Het |
| Pdgfrb |
T |
A |
18: 61,205,787 (GRCm39) |
L591* |
probably null |
Het |
| Prx |
C |
A |
7: 27,217,411 (GRCm39) |
D776E |
probably benign |
Het |
| Ptpra |
A |
G |
2: 130,384,366 (GRCm39) |
E562G |
possibly damaging |
Het |
| Rbm4b |
A |
G |
19: 4,807,359 (GRCm39) |
Y25C |
probably damaging |
Het |
| Reln |
T |
C |
5: 22,136,427 (GRCm39) |
T2534A |
probably benign |
Het |
| Rnf123 |
T |
C |
9: 107,954,963 (GRCm39) |
S14G |
probably benign |
Het |
| Rock2 |
A |
G |
12: 17,015,602 (GRCm39) |
H833R |
probably benign |
Het |
| Rxfp3 |
A |
G |
15: 11,037,111 (GRCm39) |
V87A |
possibly damaging |
Het |
| S100b |
G |
A |
10: 76,092,936 (GRCm39) |
G23D |
probably damaging |
Het |
| Scn9a |
T |
A |
2: 66,357,002 (GRCm39) |
M1100L |
probably benign |
Het |
| Septin11 |
T |
A |
5: 93,296,266 (GRCm39) |
S55T |
possibly damaging |
Het |
| Speer4a3 |
T |
C |
5: 26,154,829 (GRCm39) |
E257G |
probably damaging |
Het |
| Sv2b |
T |
A |
7: 74,769,676 (GRCm39) |
Q622L |
probably benign |
Het |
| Taar7a |
T |
C |
10: 23,868,799 (GRCm39) |
D194G |
probably benign |
Het |
| Trappc3 |
T |
C |
4: 126,169,014 (GRCm39) |
I168T |
probably benign |
Het |
| Trim27 |
T |
C |
13: 21,374,296 (GRCm39) |
|
probably null |
Het |
| Wdr49 |
G |
A |
3: 75,304,359 (GRCm39) |
T109I |
probably benign |
Het |
| Wdr64 |
T |
C |
1: 175,544,854 (GRCm39) |
Y96H |
probably damaging |
Het |
| Zfp219 |
A |
T |
14: 52,247,049 (GRCm39) |
L26Q |
probably damaging |
Het |
| Zfp758 |
T |
A |
17: 22,593,829 (GRCm39) |
V105D |
possibly damaging |
Het |
| Zfp975 |
C |
G |
7: 42,312,332 (GRCm39) |
E94Q |
possibly damaging |
Het |
| Zfyve9 |
C |
T |
4: 108,539,334 (GRCm39) |
A289T |
probably benign |
Het |
| Zscan5b |
T |
C |
7: 6,234,525 (GRCm39) |
S184P |
possibly damaging |
Het |
|
| Other mutations in Pik3c2g |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00159:Pik3c2g
|
APN |
6 |
139,841,851 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01355:Pik3c2g
|
APN |
6 |
139,798,583 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01579:Pik3c2g
|
APN |
6 |
139,700,467 (GRCm39) |
nonsense |
probably null |
|
|
IGL01580:Pik3c2g
|
APN |
6 |
139,599,514 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01587:Pik3c2g
|
APN |
6 |
139,700,467 (GRCm39) |
nonsense |
probably null |
|
|
IGL01813:Pik3c2g
|
APN |
6 |
139,599,407 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL02218:Pik3c2g
|
APN |
6 |
139,806,081 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02479:Pik3c2g
|
APN |
6 |
139,863,730 (GRCm39) |
missense |
probably benign |
0.40 |
|
IGL02480:Pik3c2g
|
APN |
6 |
139,798,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02721:Pik3c2g
|
APN |
6 |
139,682,699 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL02967:Pik3c2g
|
APN |
6 |
139,913,554 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03221:Pik3c2g
|
APN |
6 |
139,718,133 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
FR4304:Pik3c2g
|
UTSW |
6 |
139,612,654 (GRCm39) |
frame shift |
probably null |
|
|
FR4340:Pik3c2g
|
UTSW |
6 |
139,612,654 (GRCm39) |
frame shift |
probably null |
|
|
FR4976:Pik3c2g
|
UTSW |
6 |
139,612,652 (GRCm39) |
frame shift |
probably null |
|
|
IGL02837:Pik3c2g
|
UTSW |
6 |
139,603,562 (GRCm39) |
nonsense |
probably null |
|
|
PIT4531001:Pik3c2g
|
UTSW |
6 |
139,805,096 (GRCm39) |
missense |
|
|
|
R0002:Pik3c2g
|
UTSW |
6 |
139,714,471 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0081:Pik3c2g
|
UTSW |
6 |
139,903,519 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0098:Pik3c2g
|
UTSW |
6 |
139,639,441 (GRCm39) |
missense |
unknown |
|
|
R0719:Pik3c2g
|
UTSW |
6 |
139,606,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0740:Pik3c2g
|
UTSW |
6 |
139,610,791 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0837:Pik3c2g
|
UTSW |
6 |
139,903,425 (GRCm39) |
splice site |
probably benign |
|
|
R0840:Pik3c2g
|
UTSW |
6 |
139,841,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1306:Pik3c2g
|
UTSW |
6 |
139,718,154 (GRCm39) |
missense |
probably benign |
|
|
R1501:Pik3c2g
|
UTSW |
6 |
139,789,796 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1591:Pik3c2g
|
UTSW |
6 |
139,693,904 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1666:Pik3c2g
|
UTSW |
6 |
139,612,634 (GRCm39) |
intron |
probably benign |
|
|
R1907:Pik3c2g
|
UTSW |
6 |
139,789,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1970:Pik3c2g
|
UTSW |
6 |
139,846,112 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1982:Pik3c2g
|
UTSW |
6 |
139,599,546 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2171:Pik3c2g
|
UTSW |
6 |
139,801,012 (GRCm39) |
nonsense |
probably null |
|
|
R2188:Pik3c2g
|
UTSW |
6 |
139,798,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3777:Pik3c2g
|
UTSW |
6 |
139,599,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3778:Pik3c2g
|
UTSW |
6 |
139,599,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3965:Pik3c2g
|
UTSW |
6 |
139,801,018 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4076:Pik3c2g
|
UTSW |
6 |
139,798,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4078:Pik3c2g
|
UTSW |
6 |
139,612,608 (GRCm39) |
intron |
probably benign |
|
|
R4108:Pik3c2g
|
UTSW |
6 |
139,676,096 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4461:Pik3c2g
|
UTSW |
6 |
139,787,407 (GRCm39) |
intron |
probably benign |
|
|
R4474:Pik3c2g
|
UTSW |
6 |
139,610,749 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4509:Pik3c2g
|
UTSW |
6 |
139,665,732 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4646:Pik3c2g
|
UTSW |
6 |
139,665,744 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4732:Pik3c2g
|
UTSW |
6 |
139,881,711 (GRCm39) |
missense |
probably benign |
0.28 |
|
R4733:Pik3c2g
|
UTSW |
6 |
139,881,711 (GRCm39) |
missense |
probably benign |
0.28 |
|
R4854:Pik3c2g
|
UTSW |
6 |
139,714,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4928:Pik3c2g
|
UTSW |
6 |
139,913,528 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4959:Pik3c2g
|
UTSW |
6 |
139,789,657 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R4973:Pik3c2g
|
UTSW |
6 |
139,789,657 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5032:Pik3c2g
|
UTSW |
6 |
139,841,928 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5071:Pik3c2g
|
UTSW |
6 |
139,665,873 (GRCm39) |
missense |
probably null |
0.00 |
|
R5072:Pik3c2g
|
UTSW |
6 |
139,665,873 (GRCm39) |
missense |
probably null |
0.00 |
|
R5073:Pik3c2g
|
UTSW |
6 |
139,665,873 (GRCm39) |
missense |
probably null |
0.00 |
|
R5074:Pik3c2g
|
UTSW |
6 |
139,665,873 (GRCm39) |
missense |
probably null |
0.00 |
|
R5107:Pik3c2g
|
UTSW |
6 |
139,612,623 (GRCm39) |
intron |
probably benign |
|
|
R5186:Pik3c2g
|
UTSW |
6 |
139,599,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5253:Pik3c2g
|
UTSW |
6 |
139,841,983 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5359:Pik3c2g
|
UTSW |
6 |
139,599,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5394:Pik3c2g
|
UTSW |
6 |
139,665,808 (GRCm39) |
missense |
probably benign |
|
|
R5417:Pik3c2g
|
UTSW |
6 |
139,682,669 (GRCm39) |
missense |
probably benign |
|
|
R5435:Pik3c2g
|
UTSW |
6 |
139,661,581 (GRCm39) |
splice site |
probably null |
|
|
R5580:Pik3c2g
|
UTSW |
6 |
139,603,531 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5664:Pik3c2g
|
UTSW |
6 |
139,682,733 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5908:Pik3c2g
|
UTSW |
6 |
139,714,436 (GRCm39) |
missense |
|
|
|
R5914:Pik3c2g
|
UTSW |
6 |
139,599,477 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6046:Pik3c2g
|
UTSW |
6 |
139,842,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6046:Pik3c2g
|
UTSW |
6 |
139,599,137 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6298:Pik3c2g
|
UTSW |
6 |
139,603,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6382:Pik3c2g
|
UTSW |
6 |
139,665,724 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6480:Pik3c2g
|
UTSW |
6 |
139,676,195 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6917:Pik3c2g
|
UTSW |
6 |
139,841,899 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6929:Pik3c2g
|
UTSW |
6 |
139,903,502 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7022:Pik3c2g
|
UTSW |
6 |
139,599,061 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7144:Pik3c2g
|
UTSW |
6 |
139,606,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7213:Pik3c2g
|
UTSW |
6 |
139,805,990 (GRCm39) |
missense |
|
|
|
R7215:Pik3c2g
|
UTSW |
6 |
139,700,589 (GRCm39) |
missense |
|
|
|
R7332:Pik3c2g
|
UTSW |
6 |
139,841,981 (GRCm39) |
missense |
|
|
|
R7357:Pik3c2g
|
UTSW |
6 |
139,610,791 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7359:Pik3c2g
|
UTSW |
6 |
139,913,620 (GRCm39) |
missense |
unknown |
|
|
R7385:Pik3c2g
|
UTSW |
6 |
139,801,079 (GRCm39) |
missense |
|
|
|
R7455:Pik3c2g
|
UTSW |
6 |
139,913,643 (GRCm39) |
missense |
unknown |
|
|
R7651:Pik3c2g
|
UTSW |
6 |
139,599,070 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7888:Pik3c2g
|
UTSW |
6 |
139,842,470 (GRCm39) |
missense |
|
|
|
R7923:Pik3c2g
|
UTSW |
6 |
139,610,791 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7964:Pik3c2g
|
UTSW |
6 |
139,827,786 (GRCm39) |
missense |
|
|
|
R8005:Pik3c2g
|
UTSW |
6 |
139,599,067 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8371:Pik3c2g
|
UTSW |
6 |
139,881,782 (GRCm39) |
missense |
unknown |
|
|
R8724:Pik3c2g
|
UTSW |
6 |
139,913,619 (GRCm39) |
missense |
unknown |
|
|
R8733:Pik3c2g
|
UTSW |
6 |
139,714,426 (GRCm39) |
nonsense |
probably null |
|
|
R8809:Pik3c2g
|
UTSW |
6 |
139,714,436 (GRCm39) |
missense |
|
|
|
R8888:Pik3c2g
|
UTSW |
6 |
139,676,092 (GRCm39) |
nonsense |
probably null |
|
|
R8931:Pik3c2g
|
UTSW |
6 |
139,821,093 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9188:Pik3c2g
|
UTSW |
6 |
139,599,401 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9336:Pik3c2g
|
UTSW |
6 |
139,821,161 (GRCm39) |
missense |
|
|
|
R9383:Pik3c2g
|
UTSW |
6 |
139,827,742 (GRCm39) |
nonsense |
probably null |
|
|
R9524:Pik3c2g
|
UTSW |
6 |
139,606,768 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9531:Pik3c2g
|
UTSW |
6 |
139,841,926 (GRCm39) |
missense |
|
|
|
R9630:Pik3c2g
|
UTSW |
6 |
139,599,237 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9697:Pik3c2g
|
UTSW |
6 |
139,913,517 (GRCm39) |
missense |
unknown |
|
|
R9708:Pik3c2g
|
UTSW |
6 |
139,606,865 (GRCm39) |
missense |
probably benign |
|
|
RF015:Pik3c2g
|
UTSW |
6 |
139,700,497 (GRCm39) |
missense |
|
|
|
RF032:Pik3c2g
|
UTSW |
6 |
139,612,656 (GRCm39) |
frame shift |
probably null |
|
|
X0024:Pik3c2g
|
UTSW |
6 |
139,805,984 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCAAACATAAGGCCCAATG -3'
(R):5'- CCACTAATCACTCCGGTTGTTATG -3'
Sequencing Primer
(F):5'- CCCAATGATAAACAAAGCCATGGGG -3'
(R):5'- AAACATCTCCTTAATGGCACTTC -3'
|
| Posted On |
2022-10-06 |
Incidental Mutation