Incidental Mutation 'R9721:Gm9887'
ID 730808
Institutional Source Beutler Lab
Gene Symbol Gm9887
Ensembl Gene ENSMUSG00000052673
Gene Name predicted gene 9887
MMRRC Submission
Accession Numbers
Essential gene? Probably non essential (E-score: 0.141) question?
Stock # R9721 (G1)
Quality Score 195.009
Status Not validated
Chromosome 12
Chromosomal Location 69371835-69372458 bp(-) (GRCm38)
Type of Mutation missense
DNA Base Change (assembly) C to G at 69371855 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Alanine to Proline at position 202 (A202P)
Ref Sequence ENSEMBL: ENSMUSP00000058604 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000050063] [ENSMUST00000053451]
AlphaFold no structure available at present
Predicted Effect probably benign
Transcript: ENSMUST00000050063
SMART Domains Protein: ENSMUSP00000055862
Gene: ENSMUSG00000044147

ARF 1 175 2.34e-134 SMART
Predicted Effect unknown
Transcript: ENSMUST00000053451
AA Change: A202P
SMART Domains Protein: ENSMUSP00000058604
Gene: ENSMUSG00000052673
AA Change: A202P

low complexity region 13 39 N/A INTRINSIC
low complexity region 63 105 N/A INTRINSIC
low complexity region 147 164 N/A INTRINSIC
Coding Region Coverage
  • 1x: 100.0%
  • 3x: 99.9%
  • 10x: 99.7%
  • 20x: 99.1%
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 62 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700006A11Rik A T 3: 124,419,283 (GRCm38) Y120N probably benign Het
2410089E03Rik A G 15: 8,225,409 (GRCm38) T27A unknown Het
4931428F04Rik A T 8: 105,283,188 (GRCm38) D376E probably benign Het
AI314180 A T 4: 58,850,938 (GRCm38) S412T probably benign Het
Alox8 T A 11: 69,197,085 (GRCm38) H131L probably benign Het
Atp13a1 A G 8: 69,799,437 (GRCm38) E588G probably damaging Het
AU040320 G A 4: 126,839,648 (GRCm38) V654M probably damaging Het
Bicra A G 7: 15,979,176 (GRCm38) L982P probably damaging Het
Cdh11 A T 8: 102,679,625 (GRCm38) V72E probably damaging Het
Cfap65 T C 1: 74,919,342 (GRCm38) T869A probably benign Het
Ddx19a A G 8: 110,978,475 (GRCm38) F338S probably damaging Het
Dhrs7c T A 11: 67,815,078 (GRCm38) V219E probably damaging Het
Dhx33 A G 11: 71,001,598 (GRCm38) V115A probably damaging Het
Dst A G 1: 34,192,785 (GRCm38) D3153G probably benign Het
Eif5b T C 1: 38,037,659 (GRCm38) probably null Het
Ep300 A G 15: 81,608,315 (GRCm38) N284S unknown Het
Fam83a A G 15: 57,986,117 (GRCm38) N19S probably benign Het
Fgd5 A T 6: 91,988,297 (GRCm38) T504S probably benign Het
Flt4 G A 11: 49,644,433 (GRCm38) probably null Het
Ggta1 G T 2: 35,413,406 (GRCm38) D91E probably benign Het
Gls A G 1: 52,212,268 (GRCm38) V310A probably damaging Het
Gm13178 A T 4: 144,703,372 (GRCm38) V349D possibly damaging Het
Gm5414 A T 15: 101,628,147 (GRCm38) C14* probably null Het
Gm906 T C 13: 50,246,652 (GRCm38) Y546C possibly damaging Het
Ifi214 T C 1: 173,527,913 (GRCm38) T110A possibly damaging Het
Il4i1 A G 7: 44,839,689 (GRCm38) R293G probably benign Het
Itpr1 A T 6: 108,406,102 (GRCm38) T1464S probably damaging Het
Kif18a T C 2: 109,293,055 (GRCm38) S225P probably damaging Het
Kif21a A T 15: 90,971,127 (GRCm38) I678N probably damaging Het
Klf11 T A 12: 24,660,241 (GRCm38) D429E probably damaging Het
Kntc1 A G 5: 123,801,885 (GRCm38) T1581A probably benign Het
Lama2 T C 10: 27,467,342 (GRCm38) N45D possibly damaging Het
Lrrk1 T C 7: 66,274,875 (GRCm38) I1319V probably damaging Het
Ltbr G A 6: 125,307,385 (GRCm38) R365W probably damaging Het
Malrd1 C T 2: 15,696,827 (GRCm38) T751I unknown Het
Mgat5b T C 11: 116,966,769 (GRCm38) L363P probably damaging Het
Mphosph9 A T 5: 124,298,675 (GRCm38) S535R possibly damaging Het
Nckap5 C T 1: 126,027,280 (GRCm38) D512N probably damaging Het
Ngef T A 1: 87,479,135 (GRCm38) D637V probably damaging Het
Nup93 T C 8: 94,303,685 (GRCm38) Y391H probably damaging Het
Olfr1215 T C 2: 89,001,716 (GRCm38) T191A Het
Olfr1406 C A 1: 173,184,348 (GRCm38) V29F probably benign Het
Olfr1469 A T 19: 13,410,970 (GRCm38) T134S probably benign Het
Pcdhb4 C A 18: 37,309,852 (GRCm38) D738E possibly damaging Het
Pfpl G C 19: 12,428,933 (GRCm38) E183Q probably damaging Het
Phactr3 G A 2: 178,256,250 (GRCm38) E86K probably damaging Het
Psd C T 19: 46,323,189 (GRCm38) D351N probably benign Het
Pzp A G 6: 128,495,191 (GRCm38) probably null Het
Rerg T A 6: 137,056,417 (GRCm38) K106* probably null Het
Samd9l T C 6: 3,375,854 (GRCm38) E469G possibly damaging Het
Smok2b C A 17: 13,234,978 (GRCm38) Y8* probably null Het
Spn A G 7: 127,136,265 (GRCm38) S357P probably benign Het
Tek T G 4: 94,804,302 (GRCm38) W216G possibly damaging Het
Trpm3 A T 19: 22,889,398 (GRCm38) H531L probably benign Het
Trpm6 A G 19: 18,829,972 (GRCm38) M1027V probably benign Het
Tsc2 G A 17: 24,599,642 (GRCm38) R1408* probably null Het
Unc13b A G 4: 43,101,869 (GRCm38) N155D probably benign Het
Vmn1r52 G A 6: 90,179,026 (GRCm38) C104Y probably damaging Het
Xylt1 A T 7: 117,549,020 (GRCm38) E273V probably damaging Het
Zc3h4 C A 7: 16,434,845 (GRCm38) Q1035K unknown Het
Zcchc11 T A 4: 108,555,581 (GRCm38) M1493K probably benign Het
Zfp14 A T 7: 30,039,184 (GRCm38) S125R probably benign Het
Other mutations in Gm9887
AlleleSourceChrCoordTypePredicted EffectPPH Score
R4863:Gm9887 UTSW 12 69,371,989 (GRCm38) unclassified probably benign
R5448:Gm9887 UTSW 12 69,372,091 (GRCm38) unclassified probably benign
Z1176:Gm9887 UTSW 12 69,371,941 (GRCm38) missense not run
Predicted Primers PCR Primer

Sequencing Primer
Posted On 2022-10-06