Incidental Mutation 'IGL01295:Shprh'
| ID |
73091 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Shprh
|
| Ensembl Gene |
ENSMUSG00000090112 |
| Gene Name |
SNF2 histone linker PHD RING helicase |
| Synonyms |
2610103K11Rik, D230017O13Rik |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
IGL01295
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
10 |
| Chromosomal Location |
11149427-11217595 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 11183868 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 1121
(E1121G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000132870
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000044053]
[ENSMUST00000054814]
[ENSMUST00000159541]
[ENSMUST00000159810]
|
| AlphaFold |
Q7TPQ3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000044053
AA Change: E1121G
PolyPhen 2
Score 0.959 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000039422
Gene: ENSMUSG00000090112
AA Change: E1121G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
Pfam:Helicase_C
|
1500 |
1613 |
1.6e-8 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000054814
AA Change: E1121G
PolyPhen 2
Score 0.959 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000125849
Gene: ENSMUSG00000090112
AA Change: E1121G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
SCOP:d1fuka_
|
1504 |
1616 |
6e-8 |
SMART |
|
Blast:HELICc
|
1533 |
1613 |
4e-46 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000159541
AA Change: E1121G
PolyPhen 2
Score 0.959 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000132870
Gene: ENSMUSG00000090112
AA Change: E1121G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
SCOP:d1fuka_
|
1504 |
1619 |
4e-8 |
SMART |
|
Blast:HELICc
|
1533 |
1613 |
6e-46 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159553
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159810
|
| SMART Domains |
Protein: ENSMUSP00000125457
Gene: ENSMUSG00000090112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
2e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
Blast:DEXDc
|
948 |
1026 |
2e-9 |
BLAST |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006 [PubMed 17108083]).[supplied by OMIM, Mar 2008]
PHENOTYPE: The gene product is an E3 ligase involved in poly-ubiquitination of Pcna. Neither homozygous truncation nor KO affect B cell somatic hypermutation or class switching. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 67 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3425401B19Rik |
G |
T |
14: 32,661,936 (GRCm38) |
L691I |
possibly damaging |
Het |
| Ano7 |
A |
G |
1: 93,380,478 (GRCm38) |
D77G |
probably benign |
Het |
| Apol10b |
A |
T |
15: 77,585,596 (GRCm38) |
V127E |
probably damaging |
Het |
| Apol11b |
G |
A |
15: 77,638,019 (GRCm38) |
T26M |
probably damaging |
Het |
| Atn1 |
T |
C |
6: 124,749,276 (GRCm38) |
E80G |
probably damaging |
Het |
| Carmil2 |
T |
C |
8: 105,695,516 (GRCm38) |
M1139T |
probably benign |
Het |
| Cd4 |
G |
A |
6: 124,879,378 (GRCm38) |
T50I |
probably benign |
Het |
| Celf5 |
G |
T |
10: 81,467,080 (GRCm38) |
|
probably benign |
Het |
| Chd6 |
G |
A |
2: 160,988,370 (GRCm38) |
|
probably benign |
Het |
| Col12a1 |
A |
T |
9: 79,643,926 (GRCm38) |
V2136E |
probably damaging |
Het |
| Col4a1 |
G |
T |
8: 11,236,075 (GRCm38) |
|
probably benign |
Het |
| Dph1 |
A |
G |
11: 75,180,949 (GRCm38) |
|
probably benign |
Het |
| Dvl2 |
G |
T |
11: 70,009,584 (GRCm38) |
V735F |
possibly damaging |
Het |
| Eif3b |
A |
G |
5: 140,441,740 (GRCm38) |
I709V |
possibly damaging |
Het |
| Elp5 |
C |
T |
11: 69,968,470 (GRCm38) |
|
probably benign |
Het |
| Exd1 |
A |
T |
2: 119,530,079 (GRCm38) |
|
probably benign |
Het |
| Fbxl4 |
C |
A |
4: 22,427,348 (GRCm38) |
R530S |
probably benign |
Het |
| Fmo4 |
A |
T |
1: 162,799,124 (GRCm38) |
D284E |
probably damaging |
Het |
| Fn3krp |
A |
G |
11: 121,421,554 (GRCm38) |
Y31C |
probably damaging |
Het |
| Galnt14 |
G |
T |
17: 73,504,919 (GRCm38) |
Q436K |
probably benign |
Het |
| Gm5114 |
A |
T |
7: 39,407,817 (GRCm38) |
W793R |
probably damaging |
Het |
| Gm9376 |
T |
G |
14: 118,267,647 (GRCm38) |
S164A |
possibly damaging |
Het |
| Gtf2ird2 |
G |
A |
5: 134,192,764 (GRCm38) |
D69N |
probably damaging |
Het |
| Hfm1 |
A |
C |
5: 106,917,606 (GRCm38) |
M69R |
possibly damaging |
Het |
| Ighv9-1 |
A |
C |
12: 114,093,999 (GRCm38) |
S94A |
probably damaging |
Het |
| Ikzf2 |
C |
T |
1: 69,577,987 (GRCm38) |
R67H |
probably benign |
Het |
| Ipcef1 |
A |
T |
10: 6,900,642 (GRCm38) |
F316L |
probably damaging |
Het |
| Kdsr |
A |
G |
1: 106,755,457 (GRCm38) |
V62A |
possibly damaging |
Het |
| Kif23 |
A |
T |
9: 61,932,129 (GRCm38) |
C279S |
possibly damaging |
Het |
| Klf5 |
C |
T |
14: 99,301,721 (GRCm38) |
T110I |
probably benign |
Het |
| Klhl25 |
T |
A |
7: 75,865,872 (GRCm38) |
H175Q |
probably benign |
Het |
| Malrd1 |
G |
A |
2: 16,101,957 (GRCm38) |
|
probably null |
Het |
| Nfatc4 |
T |
C |
14: 55,832,505 (GRCm38) |
V710A |
probably benign |
Het |
| Olfr1404 |
A |
T |
1: 173,215,873 (GRCm38) |
Y74F |
probably damaging |
Het |
| Olfr68 |
C |
T |
7: 103,778,241 (GRCm38) |
V35I |
probably benign |
Het |
| Optn |
G |
A |
2: 5,033,156 (GRCm38) |
T409I |
possibly damaging |
Het |
| Pabpc2 |
T |
A |
18: 39,774,029 (GRCm38) |
Y116N |
probably damaging |
Het |
| Pafah1b1 |
G |
T |
11: 74,683,647 (GRCm38) |
R238S |
probably damaging |
Het |
| Pdzd9 |
C |
T |
7: 120,668,395 (GRCm38) |
G66R |
probably damaging |
Het |
| Pih1d1 |
T |
C |
7: 45,159,964 (GRCm38) |
L285P |
probably damaging |
Het |
| Pirb |
G |
A |
7: 3,717,406 (GRCm38) |
P323S |
probably damaging |
Het |
| Pkd1l1 |
A |
G |
11: 8,933,685 (GRCm38) |
F396L |
possibly damaging |
Het |
| Pla2g4d |
G |
A |
2: 120,281,726 (GRCm38) |
T108M |
probably damaging |
Het |
| Plin3 |
T |
C |
17: 56,279,814 (GRCm38) |
Y411C |
probably damaging |
Het |
| Ppfibp2 |
T |
C |
7: 107,747,539 (GRCm38) |
|
probably benign |
Het |
| Prrc2c |
T |
C |
1: 162,682,492 (GRCm38) |
S995G |
probably damaging |
Het |
| Ptf1a |
T |
C |
2: 19,446,618 (GRCm38) |
I253T |
probably damaging |
Het |
| Ptprb |
A |
G |
10: 116,362,648 (GRCm38) |
I1684V |
probably benign |
Het |
| Ptprk |
G |
A |
10: 28,475,178 (GRCm38) |
V556I |
probably benign |
Het |
| Rffl |
A |
T |
11: 82,818,457 (GRCm38) |
C47S |
probably damaging |
Het |
| Rnf17 |
C |
T |
14: 56,463,064 (GRCm38) |
Q569* |
probably null |
Het |
| Slc1a5 |
A |
G |
7: 16,795,862 (GRCm38) |
D402G |
probably damaging |
Het |
| Slc24a3 |
G |
A |
2: 145,616,714 (GRCm38) |
|
probably null |
Het |
| Slc2a13 |
T |
A |
15: 91,350,132 (GRCm38) |
|
probably null |
Het |
| Slc30a8 |
A |
T |
15: 52,306,559 (GRCm38) |
N61Y |
possibly damaging |
Het |
| Slitrk6 |
A |
T |
14: 110,751,436 (GRCm38) |
S280T |
possibly damaging |
Het |
| Smad2 |
G |
A |
18: 76,302,430 (GRCm38) |
A365T |
probably benign |
Het |
| Tcp10b |
C |
T |
17: 13,080,160 (GRCm38) |
P367S |
probably damaging |
Het |
| Tdp1 |
A |
G |
12: 99,891,670 (GRCm38) |
N163D |
probably benign |
Het |
| Thbs1 |
A |
G |
2: 118,118,327 (GRCm38) |
D488G |
possibly damaging |
Het |
| Trappc12 |
C |
T |
12: 28,746,762 (GRCm38) |
S257N |
probably damaging |
Het |
| Treml1 |
T |
C |
17: 48,365,599 (GRCm38) |
|
probably benign |
Het |
| Ugt2b36 |
A |
G |
5: 87,080,885 (GRCm38) |
V234A |
probably damaging |
Het |
| Vmn2r86 |
T |
G |
10: 130,453,026 (GRCm38) |
H202P |
probably damaging |
Het |
| Vmn2r87 |
C |
A |
10: 130,472,009 (GRCm38) |
V787F |
probably damaging |
Het |
| Wbp2nl |
T |
A |
15: 82,306,418 (GRCm38) |
M129K |
probably damaging |
Het |
| Zdhhc15 |
T |
C |
X: 104,544,913 (GRCm38) |
|
probably null |
Het |
|
| Other mutations in Shprh |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00492:Shprh
|
APN |
10 |
11,188,158 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00583:Shprh
|
APN |
10 |
11,188,020 (GRCm38) |
missense |
probably benign |
0.37 |
|
IGL00684:Shprh
|
APN |
10 |
11,163,037 (GRCm38) |
missense |
probably benign |
0.11 |
|
IGL01387:Shprh
|
APN |
10 |
11,170,254 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01635:Shprh
|
APN |
10 |
11,170,019 (GRCm38) |
nonsense |
probably null |
|
|
IGL01833:Shprh
|
APN |
10 |
11,191,062 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02013:Shprh
|
APN |
10 |
11,181,502 (GRCm38) |
splice site |
probably benign |
|
|
IGL02502:Shprh
|
APN |
10 |
11,194,357 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
IGL02819:Shprh
|
APN |
10 |
11,154,765 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
PIT4581001:Shprh
|
UTSW |
10 |
11,192,494 (GRCm38) |
frame shift |
probably null |
|
|
R0010:Shprh
|
UTSW |
10 |
11,151,931 (GRCm38) |
missense |
probably benign |
|
|
R0010:Shprh
|
UTSW |
10 |
11,151,931 (GRCm38) |
missense |
probably benign |
|
|
R0053:Shprh
|
UTSW |
10 |
11,194,372 (GRCm38) |
splice site |
probably null |
|
|
R0053:Shprh
|
UTSW |
10 |
11,194,372 (GRCm38) |
splice site |
probably null |
|
|
R0255:Shprh
|
UTSW |
10 |
11,186,391 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R0325:Shprh
|
UTSW |
10 |
11,170,109 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0331:Shprh
|
UTSW |
10 |
11,194,170 (GRCm38) |
splice site |
probably benign |
|
|
R0494:Shprh
|
UTSW |
10 |
11,157,191 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0532:Shprh
|
UTSW |
10 |
11,162,812 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R0546:Shprh
|
UTSW |
10 |
11,183,887 (GRCm38) |
splice site |
probably benign |
|
|
R0574:Shprh
|
UTSW |
10 |
11,163,077 (GRCm38) |
unclassified |
probably benign |
|
|
R0605:Shprh
|
UTSW |
10 |
11,207,112 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0662:Shprh
|
UTSW |
10 |
11,186,847 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1148:Shprh
|
UTSW |
10 |
11,213,482 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1148:Shprh
|
UTSW |
10 |
11,213,482 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1263:Shprh
|
UTSW |
10 |
11,159,530 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1588:Shprh
|
UTSW |
10 |
11,164,744 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1638:Shprh
|
UTSW |
10 |
11,157,078 (GRCm38) |
missense |
probably benign |
|
|
R1830:Shprh
|
UTSW |
10 |
11,186,911 (GRCm38) |
splice site |
probably null |
|
|
R1898:Shprh
|
UTSW |
10 |
11,186,869 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1903:Shprh
|
UTSW |
10 |
11,183,797 (GRCm38) |
nonsense |
probably null |
|
|
R2060:Shprh
|
UTSW |
10 |
11,152,120 (GRCm38) |
missense |
probably benign |
0.03 |
|
R2225:Shprh
|
UTSW |
10 |
11,162,235 (GRCm38) |
unclassified |
probably benign |
|
|
R2363:Shprh
|
UTSW |
10 |
11,171,953 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2509:Shprh
|
UTSW |
10 |
11,166,724 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2891:Shprh
|
UTSW |
10 |
11,164,356 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3077:Shprh
|
UTSW |
10 |
11,170,413 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3150:Shprh
|
UTSW |
10 |
11,170,030 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R3796:Shprh
|
UTSW |
10 |
11,178,757 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R4196:Shprh
|
UTSW |
10 |
11,207,860 (GRCm38) |
utr 3 prime |
probably benign |
|
|
R4423:Shprh
|
UTSW |
10 |
11,186,518 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R4488:Shprh
|
UTSW |
10 |
11,160,471 (GRCm38) |
missense |
probably benign |
0.17 |
|
R4748:Shprh
|
UTSW |
10 |
11,170,476 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4768:Shprh
|
UTSW |
10 |
11,181,540 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4867:Shprh
|
UTSW |
10 |
11,164,557 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4937:Shprh
|
UTSW |
10 |
11,157,119 (GRCm38) |
missense |
probably benign |
|
|
R5140:Shprh
|
UTSW |
10 |
11,154,705 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5318:Shprh
|
UTSW |
10 |
11,166,557 (GRCm38) |
missense |
probably benign |
0.04 |
|
R5323:Shprh
|
UTSW |
10 |
11,170,297 (GRCm38) |
splice site |
probably null |
|
|
R5450:Shprh
|
UTSW |
10 |
11,212,330 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R5872:Shprh
|
UTSW |
10 |
11,188,073 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6030:Shprh
|
UTSW |
10 |
11,151,991 (GRCm38) |
missense |
probably benign |
0.37 |
|
R6030:Shprh
|
UTSW |
10 |
11,151,991 (GRCm38) |
missense |
probably benign |
0.37 |
|
R6392:Shprh
|
UTSW |
10 |
11,178,741 (GRCm38) |
nonsense |
probably null |
|
|
R6416:Shprh
|
UTSW |
10 |
11,167,873 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6470:Shprh
|
UTSW |
10 |
11,171,937 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6513:Shprh
|
UTSW |
10 |
11,186,893 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6530:Shprh
|
UTSW |
10 |
11,194,267 (GRCm38) |
missense |
probably benign |
0.02 |
|
R6678:Shprh
|
UTSW |
10 |
11,166,545 (GRCm38) |
missense |
probably benign |
0.16 |
|
R6757:Shprh
|
UTSW |
10 |
11,181,508 (GRCm38) |
splice site |
probably null |
|
|
R6971:Shprh
|
UTSW |
10 |
11,166,693 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7158:Shprh
|
UTSW |
10 |
11,166,730 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7582:Shprh
|
UTSW |
10 |
11,164,705 (GRCm38) |
missense |
probably benign |
|
|
R7757:Shprh
|
UTSW |
10 |
11,162,180 (GRCm38) |
missense |
probably benign |
0.30 |
|
R7812:Shprh
|
UTSW |
10 |
11,151,991 (GRCm38) |
missense |
probably benign |
|
|
R7998:Shprh
|
UTSW |
10 |
11,185,341 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8061:Shprh
|
UTSW |
10 |
11,212,333 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R8082:Shprh
|
UTSW |
10 |
11,151,811 (GRCm38) |
missense |
probably benign |
0.22 |
|
R8116:Shprh
|
UTSW |
10 |
11,213,461 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8390:Shprh
|
UTSW |
10 |
11,187,983 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R8445:Shprh
|
UTSW |
10 |
11,181,569 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R8530:Shprh
|
UTSW |
10 |
11,151,934 (GRCm38) |
missense |
probably benign |
0.37 |
|
R8759:Shprh
|
UTSW |
10 |
11,157,164 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R8937:Shprh
|
UTSW |
10 |
11,185,437 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
R8995:Shprh
|
UTSW |
10 |
11,164,830 (GRCm38) |
nonsense |
probably null |
|
|
R9053:Shprh
|
UTSW |
10 |
11,154,702 (GRCm38) |
missense |
probably benign |
0.04 |
|
R9131:Shprh
|
UTSW |
10 |
11,162,845 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R9176:Shprh
|
UTSW |
10 |
11,160,576 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9391:Shprh
|
UTSW |
10 |
11,162,889 (GRCm38) |
missense |
probably benign |
0.05 |
|
R9423:Shprh
|
UTSW |
10 |
11,205,263 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9563:Shprh
|
UTSW |
10 |
11,166,491 (GRCm38) |
nonsense |
probably null |
|
|
R9668:Shprh
|
UTSW |
10 |
11,206,332 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9709:Shprh
|
UTSW |
10 |
11,162,830 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R9718:Shprh
|
UTSW |
10 |
11,213,504 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9750:Shprh
|
UTSW |
10 |
11,164,460 (GRCm38) |
missense |
probably damaging |
0.98 |
|
RF012:Shprh
|
UTSW |
10 |
11,164,841 (GRCm38) |
missense |
probably benign |
0.02 |
|
V8831:Shprh
|
UTSW |
10 |
11,186,862 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Shprh
|
UTSW |
10 |
11,186,447 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Shprh
|
UTSW |
10 |
11,164,553 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Shprh
|
UTSW |
10 |
11,151,762 (GRCm38) |
frame shift |
probably null |
|
|
| Posted On |
2013-10-07 |
Incidental Mutation