Incidental Mutation 'R9287:Pcnx1'
| ID |
731338 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcnx1
|
| Ensembl Gene |
ENSMUSG00000021140 |
| Gene Name |
pecanex 1 |
| Synonyms |
3526401J03Rik, 2900024E21Rik, Pcnx |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9287 (G1)
|
| Quality Score |
222.009 |
|
Status
|
Validated
|
| Chromosome |
12 |
| Chromosomal Location |
81906797-82047698 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 82042323 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 38
(S38T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000152168
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000021567]
[ENSMUST00000221721]
[ENSMUST00000222005]
[ENSMUST00000222468]
|
| AlphaFold |
Q9QYC1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000021567
|
| SMART Domains |
Protein: ENSMUSP00000021567
Gene: ENSMUSG00000021140
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
28 |
50 |
N/A |
INTRINSIC |
|
transmembrane domain
|
52 |
74 |
N/A |
INTRINSIC |
|
low complexity region
|
369 |
390 |
N/A |
INTRINSIC |
|
low complexity region
|
407 |
422 |
N/A |
INTRINSIC |
|
low complexity region
|
509 |
525 |
N/A |
INTRINSIC |
|
low complexity region
|
616 |
638 |
N/A |
INTRINSIC |
|
low complexity region
|
672 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
764 |
783 |
N/A |
INTRINSIC |
|
low complexity region
|
817 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
842 |
853 |
N/A |
INTRINSIC |
|
low complexity region
|
911 |
922 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1006 |
1028 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1035 |
1052 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1070 |
1092 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1113 |
1135 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1163 |
1185 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1197 |
1216 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1269 |
1291 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1298 |
1315 |
N/A |
INTRINSIC |
|
Pfam:Pecanex_C
|
1785 |
2011 |
1.6e-118 |
PFAM |
|
low complexity region
|
2125 |
2140 |
N/A |
INTRINSIC |
|
low complexity region
|
2195 |
2202 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000221675
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000221721
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000222005
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000222468
AA Change: S38T
PolyPhen 2
Score 0.074 (Sensitivity: 0.93; Specificity: 0.85)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
100% (109/109) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes an evolutionarily conserved transmembrane protein similar to the pecanex protein in Drosophila. The fly protein is a component of the Notch signaling pathway, which functions in several developmental processes. [provided by RefSeq, Jul 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 108 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9430097D07Rik |
T |
A |
2: 32,465,178 (GRCm39) |
|
probably benign |
Het |
| Aadacl2 |
C |
A |
3: 59,932,573 (GRCm39) |
H363N |
probably damaging |
Het |
| Ace3 |
T |
G |
11: 105,888,246 (GRCm39) |
S319A |
probably damaging |
Het |
| Amer3 |
C |
T |
1: 34,627,900 (GRCm39) |
P713L |
possibly damaging |
Het |
| Aoah |
T |
C |
13: 21,186,879 (GRCm39) |
L453P |
probably damaging |
Het |
| Asz1 |
A |
T |
6: 18,051,290 (GRCm39) |
L463Q |
possibly damaging |
Het |
| Bpifb6 |
T |
A |
2: 153,746,535 (GRCm39) |
V143D |
probably damaging |
Het |
| Cad |
T |
A |
5: 31,230,000 (GRCm39) |
M1499K |
possibly damaging |
Het |
| Casp9 |
T |
A |
4: 141,534,471 (GRCm39) |
C294S |
probably benign |
Het |
| Ccdc7b |
T |
A |
8: 129,890,321 (GRCm39) |
S65T |
probably benign |
Het |
| Cdh23 |
G |
A |
10: 60,143,306 (GRCm39) |
A3005V |
possibly damaging |
Het |
| Cfap54 |
T |
C |
10: 92,805,565 (GRCm39) |
Y1515C |
possibly damaging |
Het |
| Chrm5 |
A |
C |
2: 112,309,610 (GRCm39) |
F502C |
probably damaging |
Het |
| Cnst |
A |
T |
1: 179,407,108 (GRCm39) |
T52S |
possibly damaging |
Het |
| Cntn6 |
T |
C |
6: 104,809,471 (GRCm39) |
I502T |
possibly damaging |
Het |
| Col7a1 |
G |
A |
9: 108,787,457 (GRCm39) |
V617M |
unknown |
Het |
| Ctsb |
A |
G |
14: 63,370,875 (GRCm39) |
D29G |
probably benign |
Het |
| Cyp3a44 |
T |
A |
5: 145,725,202 (GRCm39) |
Q333L |
possibly damaging |
Het |
| Dnajc27 |
T |
C |
12: 4,146,256 (GRCm39) |
V95A |
possibly damaging |
Het |
| Eea1 |
T |
A |
10: 95,831,445 (GRCm39) |
Y179N |
probably damaging |
Het |
| Erbb2 |
T |
C |
11: 98,326,107 (GRCm39) |
M961T |
probably damaging |
Het |
| Fat4 |
G |
A |
3: 38,945,781 (GRCm39) |
G1558D |
probably damaging |
Het |
| Foxh1 |
T |
C |
15: 76,553,126 (GRCm39) |
E196G |
probably damaging |
Het |
| Gcc2 |
T |
A |
10: 58,105,217 (GRCm39) |
L151* |
probably null |
Het |
| Gcdh |
C |
T |
8: 85,616,313 (GRCm39) |
G294D |
probably damaging |
Het |
| Gcnt3 |
A |
T |
9: 69,941,693 (GRCm39) |
F292I |
probably damaging |
Het |
| Glod4 |
T |
C |
11: 76,128,510 (GRCm39) |
S131G |
probably benign |
Het |
| Gpc2 |
G |
A |
5: 138,272,586 (GRCm39) |
L576F |
unknown |
Het |
| Gphn |
G |
A |
12: 78,609,646 (GRCm39) |
S330N |
possibly damaging |
Het |
| Heatr5a |
C |
T |
12: 51,967,260 (GRCm39) |
C872Y |
probably damaging |
Het |
| Hephl1 |
G |
A |
9: 14,995,775 (GRCm39) |
S449L |
probably benign |
Het |
| Hrh2 |
G |
T |
13: 54,368,358 (GRCm39) |
M111I |
probably benign |
Het |
| Igfn1 |
A |
G |
1: 135,925,544 (GRCm39) |
V70A |
probably benign |
Het |
| Il2 |
G |
A |
3: 37,179,988 (GRCm39) |
T23I |
probably damaging |
Het |
| Irak4 |
A |
G |
15: 94,460,917 (GRCm39) |
T382A |
possibly damaging |
Het |
| Itih2 |
A |
G |
2: 10,128,297 (GRCm39) |
S135P |
possibly damaging |
Het |
| Kansl3 |
C |
T |
1: 36,388,497 (GRCm39) |
D457N |
probably damaging |
Het |
| Kcns3 |
A |
G |
12: 11,141,601 (GRCm39) |
I366T |
probably damaging |
Het |
| Kif26a |
C |
A |
12: 112,145,719 (GRCm39) |
Y1743* |
probably null |
Het |
| Lama4 |
A |
T |
10: 38,981,960 (GRCm39) |
I1730F |
probably damaging |
Het |
| Lax1 |
T |
C |
1: 133,607,931 (GRCm39) |
N270S |
probably benign |
Het |
| Lrp1 |
G |
T |
10: 127,403,233 (GRCm39) |
D2113E |
probably damaging |
Het |
| Lrp6 |
A |
G |
6: 134,483,259 (GRCm39) |
V482A |
probably benign |
Het |
| Luzp2 |
A |
G |
7: 54,914,108 (GRCm39) |
|
probably benign |
Het |
| Mc5r |
C |
A |
18: 68,472,200 (GRCm39) |
D186E |
probably damaging |
Het |
| Mcph1 |
A |
T |
8: 18,657,293 (GRCm39) |
|
probably null |
Het |
| Mgam |
A |
G |
6: 40,705,905 (GRCm39) |
|
probably benign |
Het |
| Mmrn1 |
A |
C |
6: 60,952,939 (GRCm39) |
T407P |
probably damaging |
Het |
| Mrpl1 |
T |
C |
5: 96,386,806 (GRCm39) |
V265A |
probably benign |
Het |
| Mrpl15 |
C |
T |
1: 4,846,856 (GRCm39) |
G240D |
probably damaging |
Het |
| Msx1 |
A |
T |
5: 37,978,795 (GRCm39) |
M240K |
probably damaging |
Het |
| Mtf1 |
T |
C |
4: 124,724,934 (GRCm39) |
L337P |
probably damaging |
Het |
| Muc5ac |
T |
A |
7: 141,361,626 (GRCm39) |
C1646S |
probably damaging |
Het |
| Mvb12a |
C |
A |
8: 71,999,638 (GRCm39) |
T219N |
probably damaging |
Het |
| Myo16 |
G |
A |
8: 10,526,114 (GRCm39) |
V885M |
unknown |
Het |
| N4bp2 |
T |
A |
5: 65,960,855 (GRCm39) |
S509T |
probably benign |
Het |
| Nckap1 |
A |
G |
2: 80,383,750 (GRCm39) |
V144A |
possibly damaging |
Het |
| Nkx2-6 |
G |
T |
14: 69,412,404 (GRCm39) |
G191C |
possibly damaging |
Het |
| Nmnat2 |
T |
C |
1: 152,962,138 (GRCm39) |
I126T |
probably damaging |
Het |
| Nrp2 |
C |
T |
1: 62,835,014 (GRCm39) |
R863W |
probably damaging |
Het |
| Nup188 |
C |
T |
2: 30,226,726 (GRCm39) |
R1168C |
probably damaging |
Het |
| Oas3 |
T |
A |
5: 120,892,754 (GRCm39) |
D1091V |
probably damaging |
Het |
| Optn |
T |
A |
2: 5,036,126 (GRCm39) |
Q452L |
probably damaging |
Het |
| Or8b47 |
C |
T |
9: 38,435,082 (GRCm39) |
T18I |
probably damaging |
Het |
| Pcca |
G |
A |
14: 122,854,178 (GRCm39) |
V157I |
probably benign |
Het |
| Pcdha9 |
A |
G |
18: 37,132,281 (GRCm39) |
D450G |
probably benign |
Het |
| Phrf1 |
C |
G |
7: 140,840,055 (GRCm39) |
D1083E |
probably benign |
Het |
| Plaat5 |
T |
A |
19: 7,596,691 (GRCm39) |
Y159* |
probably null |
Het |
| Plcb4 |
G |
A |
2: 135,829,817 (GRCm39) |
A947T |
probably benign |
Het |
| Ppp1r3g |
G |
A |
13: 36,152,834 (GRCm39) |
D85N |
possibly damaging |
Het |
| Pramel34 |
G |
A |
5: 93,785,969 (GRCm39) |
H104Y |
possibly damaging |
Het |
| Prom2 |
A |
C |
2: 127,380,185 (GRCm39) |
V349G |
probably damaging |
Het |
| Prrc2c |
C |
T |
1: 162,541,843 (GRCm39) |
S382N |
probably benign |
Het |
| Rai14 |
A |
T |
15: 10,592,204 (GRCm39) |
N230K |
probably benign |
Het |
| Rexo5 |
A |
T |
7: 119,402,025 (GRCm39) |
K142I |
probably damaging |
Het |
| Rgs22 |
T |
C |
15: 36,098,409 (GRCm39) |
H484R |
probably damaging |
Het |
| Rims2 |
C |
T |
15: 39,543,086 (GRCm39) |
A1440V |
probably damaging |
Het |
| Serpinb1a |
T |
C |
13: 33,026,946 (GRCm39) |
E332G |
probably damaging |
Het |
| Sh2b1 |
TGGGGACCAGCTCAGCCACGGGGACCAGCTC |
TGGGGACCAGCTCAGCCACGGGGACCAGCTCAGCCACGGGGACCAGCTC |
7: 126,066,742 (GRCm39) |
|
probably benign |
Het |
| Slc26a7 |
C |
T |
4: 14,516,165 (GRCm39) |
G555S |
possibly damaging |
Het |
| Slc4a2 |
A |
T |
5: 24,639,123 (GRCm39) |
D386V |
probably damaging |
Het |
| Slc6a17 |
C |
T |
3: 107,384,551 (GRCm39) |
V350M |
probably damaging |
Het |
| Smc2 |
A |
G |
4: 52,449,361 (GRCm39) |
Y174C |
probably damaging |
Het |
| Smoc2 |
A |
G |
17: 14,619,686 (GRCm39) |
Y355C |
probably damaging |
Het |
| Smpd1 |
T |
A |
7: 105,204,442 (GRCm39) |
V107E |
probably benign |
Het |
| Snapc1 |
T |
C |
12: 74,018,773 (GRCm39) |
|
probably benign |
Het |
| Spata31e2 |
T |
C |
1: 26,722,426 (GRCm39) |
D918G |
possibly damaging |
Het |
| Steap4 |
T |
G |
5: 8,026,683 (GRCm39) |
F215L |
probably benign |
Het |
| Tbc1d1 |
T |
A |
5: 64,435,364 (GRCm39) |
S501T |
probably damaging |
Het |
| Tec |
A |
G |
5: 72,926,117 (GRCm39) |
Y312H |
probably damaging |
Het |
| Ticrr |
C |
A |
7: 79,343,516 (GRCm39) |
T1127K |
possibly damaging |
Het |
| Tlk2 |
A |
G |
11: 105,147,722 (GRCm39) |
D438G |
probably benign |
Het |
| Tln2 |
C |
A |
9: 67,277,980 (GRCm39) |
V343L |
probably benign |
Het |
| Tmem156 |
T |
A |
5: 65,231,148 (GRCm39) |
I241F |
probably damaging |
Het |
| Tmtc1 |
G |
T |
6: 148,186,390 (GRCm39) |
N559K |
probably benign |
Het |
| Trbv4 |
A |
T |
6: 41,036,696 (GRCm39) |
I74F |
probably benign |
Het |
| Trmt1l |
C |
T |
1: 151,328,899 (GRCm39) |
P524S |
probably damaging |
Het |
| Trpa1 |
A |
T |
1: 14,956,040 (GRCm39) |
C776* |
probably null |
Het |
| Ttc41 |
T |
A |
10: 86,599,830 (GRCm39) |
S1043R |
probably benign |
Het |
| Ttn |
A |
G |
2: 76,576,646 (GRCm39) |
L24749S |
probably damaging |
Het |
| Ube2o |
C |
T |
11: 116,471,942 (GRCm39) |
G100R |
probably damaging |
Het |
| Unc5b |
T |
C |
10: 60,609,532 (GRCm39) |
E588G |
possibly damaging |
Het |
| Usp43 |
G |
T |
11: 67,770,922 (GRCm39) |
Q571K |
probably damaging |
Het |
| Vmn1r127 |
G |
A |
7: 21,052,927 (GRCm39) |
P287L |
possibly damaging |
Het |
| Wasf3 |
T |
A |
5: 146,397,857 (GRCm39) |
M208K |
possibly damaging |
Het |
| Xab2 |
A |
G |
8: 3,663,000 (GRCm39) |
F527S |
possibly damaging |
Het |
| Zfp644 |
T |
G |
5: 106,785,774 (GRCm39) |
N258H |
possibly damaging |
Het |
| Zfp947 |
A |
C |
17: 22,364,594 (GRCm39) |
F360C |
probably damaging |
Het |
|
| Other mutations in Pcnx1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00164:Pcnx1
|
APN |
12 |
81,941,875 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL00561:Pcnx1
|
APN |
12 |
82,042,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01066:Pcnx1
|
APN |
12 |
82,038,795 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01069:Pcnx1
|
APN |
12 |
81,964,918 (GRCm39) |
missense |
probably benign |
0.27 |
|
IGL01082:Pcnx1
|
APN |
12 |
82,037,372 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
IGL01087:Pcnx1
|
APN |
12 |
82,042,113 (GRCm39) |
splice site |
probably benign |
|
|
IGL01145:Pcnx1
|
APN |
12 |
82,038,809 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01412:Pcnx1
|
APN |
12 |
81,953,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01477:Pcnx1
|
APN |
12 |
82,020,015 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01639:Pcnx1
|
APN |
12 |
81,997,094 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01815:Pcnx1
|
APN |
12 |
82,037,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01870:Pcnx1
|
APN |
12 |
82,022,667 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01902:Pcnx1
|
APN |
12 |
82,025,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01935:Pcnx1
|
APN |
12 |
81,964,590 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02141:Pcnx1
|
APN |
12 |
81,907,156 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL02179:Pcnx1
|
APN |
12 |
81,980,493 (GRCm39) |
intron |
probably benign |
|
|
IGL02197:Pcnx1
|
APN |
12 |
82,039,925 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02197:Pcnx1
|
APN |
12 |
81,965,878 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02238:Pcnx1
|
APN |
12 |
81,964,688 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02430:Pcnx1
|
APN |
12 |
81,966,096 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02590:Pcnx1
|
APN |
12 |
82,041,752 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02992:Pcnx1
|
APN |
12 |
82,010,894 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03304:Pcnx1
|
APN |
12 |
82,028,803 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4515001:Pcnx1
|
UTSW |
12 |
82,038,561 (GRCm39) |
missense |
|
|
|
R0086:Pcnx1
|
UTSW |
12 |
82,038,832 (GRCm39) |
unclassified |
probably benign |
|
|
R0114:Pcnx1
|
UTSW |
12 |
82,042,869 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0240:Pcnx1
|
UTSW |
12 |
81,993,792 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R0240:Pcnx1
|
UTSW |
12 |
81,993,792 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R0376:Pcnx1
|
UTSW |
12 |
82,021,353 (GRCm39) |
splice site |
probably benign |
|
|
R0377:Pcnx1
|
UTSW |
12 |
82,021,353 (GRCm39) |
splice site |
probably benign |
|
|
R0416:Pcnx1
|
UTSW |
12 |
82,021,240 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0514:Pcnx1
|
UTSW |
12 |
82,041,884 (GRCm39) |
missense |
probably benign |
0.21 |
|
R0563:Pcnx1
|
UTSW |
12 |
81,964,718 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0569:Pcnx1
|
UTSW |
12 |
82,038,804 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0626:Pcnx1
|
UTSW |
12 |
82,030,450 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R0972:Pcnx1
|
UTSW |
12 |
81,960,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1205:Pcnx1
|
UTSW |
12 |
82,003,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1455:Pcnx1
|
UTSW |
12 |
82,020,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1514:Pcnx1
|
UTSW |
12 |
81,965,572 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1731:Pcnx1
|
UTSW |
12 |
82,037,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Pcnx1
|
UTSW |
12 |
82,030,258 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1774:Pcnx1
|
UTSW |
12 |
82,022,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1817:Pcnx1
|
UTSW |
12 |
81,965,416 (GRCm39) |
missense |
probably benign |
|
|
R1843:Pcnx1
|
UTSW |
12 |
82,027,709 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1862:Pcnx1
|
UTSW |
12 |
81,965,506 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2042:Pcnx1
|
UTSW |
12 |
81,965,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2054:Pcnx1
|
UTSW |
12 |
81,980,448 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2243:Pcnx1
|
UTSW |
12 |
81,965,479 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2272:Pcnx1
|
UTSW |
12 |
82,042,088 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2360:Pcnx1
|
UTSW |
12 |
81,996,960 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2926:Pcnx1
|
UTSW |
12 |
82,041,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3607:Pcnx1
|
UTSW |
12 |
81,975,066 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3781:Pcnx1
|
UTSW |
12 |
82,042,892 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3782:Pcnx1
|
UTSW |
12 |
82,042,892 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3806:Pcnx1
|
UTSW |
12 |
81,996,911 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R3926:Pcnx1
|
UTSW |
12 |
82,005,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4019:Pcnx1
|
UTSW |
12 |
81,965,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4020:Pcnx1
|
UTSW |
12 |
81,965,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4683:Pcnx1
|
UTSW |
12 |
82,033,446 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4703:Pcnx1
|
UTSW |
12 |
81,941,938 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4732:Pcnx1
|
UTSW |
12 |
82,042,525 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4733:Pcnx1
|
UTSW |
12 |
82,042,525 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4755:Pcnx1
|
UTSW |
12 |
81,997,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4792:Pcnx1
|
UTSW |
12 |
81,965,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4897:Pcnx1
|
UTSW |
12 |
81,964,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4915:Pcnx1
|
UTSW |
12 |
82,021,269 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4934:Pcnx1
|
UTSW |
12 |
82,038,599 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R4940:Pcnx1
|
UTSW |
12 |
81,964,567 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R5079:Pcnx1
|
UTSW |
12 |
82,025,863 (GRCm39) |
nonsense |
probably null |
|
|
R5087:Pcnx1
|
UTSW |
12 |
82,041,713 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5284:Pcnx1
|
UTSW |
12 |
81,965,803 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5287:Pcnx1
|
UTSW |
12 |
82,028,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5436:Pcnx1
|
UTSW |
12 |
81,907,180 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5505:Pcnx1
|
UTSW |
12 |
81,996,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5538:Pcnx1
|
UTSW |
12 |
81,907,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5632:Pcnx1
|
UTSW |
12 |
81,964,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5642:Pcnx1
|
UTSW |
12 |
81,941,803 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
R5841:Pcnx1
|
UTSW |
12 |
81,965,429 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R6275:Pcnx1
|
UTSW |
12 |
81,965,381 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6508:Pcnx1
|
UTSW |
12 |
81,959,479 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6532:Pcnx1
|
UTSW |
12 |
82,027,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6634:Pcnx1
|
UTSW |
12 |
81,964,656 (GRCm39) |
nonsense |
probably null |
|
|
R6753:Pcnx1
|
UTSW |
12 |
82,011,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6776:Pcnx1
|
UTSW |
12 |
82,009,496 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6778:Pcnx1
|
UTSW |
12 |
81,965,645 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6890:Pcnx1
|
UTSW |
12 |
82,018,150 (GRCm39) |
missense |
probably benign |
0.09 |
|
R6894:Pcnx1
|
UTSW |
12 |
82,034,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6927:Pcnx1
|
UTSW |
12 |
81,964,586 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7173:Pcnx1
|
UTSW |
12 |
81,999,777 (GRCm39) |
splice site |
probably null |
|
|
R7196:Pcnx1
|
UTSW |
12 |
82,042,312 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7316:Pcnx1
|
UTSW |
12 |
82,042,323 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7559:Pcnx1
|
UTSW |
12 |
82,039,896 (GRCm39) |
missense |
unknown |
|
|
R7635:Pcnx1
|
UTSW |
12 |
81,965,899 (GRCm39) |
missense |
|
|
|
R7669:Pcnx1
|
UTSW |
12 |
82,037,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8021:Pcnx1
|
UTSW |
12 |
81,965,593 (GRCm39) |
nonsense |
probably null |
|
|
R8049:Pcnx1
|
UTSW |
12 |
81,965,593 (GRCm39) |
nonsense |
probably null |
|
|
R8078:Pcnx1
|
UTSW |
12 |
82,022,054 (GRCm39) |
missense |
|
|
|
R8093:Pcnx1
|
UTSW |
12 |
81,965,593 (GRCm39) |
nonsense |
probably null |
|
|
R8104:Pcnx1
|
UTSW |
12 |
82,030,385 (GRCm39) |
nonsense |
probably null |
|
|
R8108:Pcnx1
|
UTSW |
12 |
81,965,593 (GRCm39) |
nonsense |
probably null |
|
|
R8109:Pcnx1
|
UTSW |
12 |
81,965,593 (GRCm39) |
nonsense |
probably null |
|
|
R8131:Pcnx1
|
UTSW |
12 |
81,965,292 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8136:Pcnx1
|
UTSW |
12 |
81,964,780 (GRCm39) |
missense |
probably benign |
|
|
R8153:Pcnx1
|
UTSW |
12 |
81,965,593 (GRCm39) |
nonsense |
probably null |
|
|
R8156:Pcnx1
|
UTSW |
12 |
81,965,593 (GRCm39) |
nonsense |
probably null |
|
|
R8202:Pcnx1
|
UTSW |
12 |
81,941,821 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8362:Pcnx1
|
UTSW |
12 |
82,013,830 (GRCm39) |
missense |
|
|
|
R8515:Pcnx1
|
UTSW |
12 |
82,009,490 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8803:Pcnx1
|
UTSW |
12 |
82,039,925 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8820:Pcnx1
|
UTSW |
12 |
82,020,022 (GRCm39) |
missense |
|
|
|
R8828:Pcnx1
|
UTSW |
12 |
82,042,597 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8946:Pcnx1
|
UTSW |
12 |
82,018,158 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8964:Pcnx1
|
UTSW |
12 |
82,039,812 (GRCm39) |
missense |
|
|
|
R9152:Pcnx1
|
UTSW |
12 |
82,022,589 (GRCm39) |
missense |
|
|
|
R9256:Pcnx1
|
UTSW |
12 |
82,020,047 (GRCm39) |
missense |
|
|
|
R9289:Pcnx1
|
UTSW |
12 |
82,028,853 (GRCm39) |
missense |
|
|
|
R9414:Pcnx1
|
UTSW |
12 |
81,964,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9445:Pcnx1
|
UTSW |
12 |
81,964,981 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9595:Pcnx1
|
UTSW |
12 |
81,965,688 (GRCm39) |
missense |
|
|
|
R9600:Pcnx1
|
UTSW |
12 |
82,030,435 (GRCm39) |
missense |
|
|
|
R9620:Pcnx1
|
UTSW |
12 |
81,996,960 (GRCm39) |
missense |
probably damaging |
0.99 |
|
RF024:Pcnx1
|
UTSW |
12 |
81,964,501 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Pcnx1
|
UTSW |
12 |
81,965,451 (GRCm39) |
missense |
|
|
|
Z1177:Pcnx1
|
UTSW |
12 |
81,964,976 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTTCCCATGCCAGAAAGGGG -3'
(R):5'- ACAGACACATGAGGATCACTG -3'
Sequencing Primer
(F):5'- ATTTACAGAGTCCAGGTGAGTAGGTC -3'
(R):5'- ATGAGGATCACTGCCAGCTC -3'
|
| Posted On |
2022-11-02 |
Incidental Mutation