Incidental Mutation 'R9748:Nckap5'
| ID |
732281 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nckap5
|
| Ensembl Gene |
ENSMUSG00000049690 |
| Gene Name |
NCK-associated protein 5 |
| Synonyms |
LOC380609, D130011D22Rik, E030049G20Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9748 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
125841373-126758529 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 125953939 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Leucine
at position 871
(P871L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125624
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000057846]
[ENSMUST00000094609]
[ENSMUST00000094610]
[ENSMUST00000112583]
[ENSMUST00000161954]
[ENSMUST00000162877]
|
| AlphaFold |
E9QAE1 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000057846
AA Change: P807L
PolyPhen 2
Score 0.613 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000062229
Gene: ENSMUSG00000049690
AA Change: P807L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
25 |
N/A |
INTRINSIC |
|
coiled coil region
|
108 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
321 |
332 |
N/A |
INTRINSIC |
|
low complexity region
|
755 |
771 |
N/A |
INTRINSIC |
|
low complexity region
|
950 |
971 |
N/A |
INTRINSIC |
|
low complexity region
|
1070 |
1085 |
N/A |
INTRINSIC |
|
low complexity region
|
1181 |
1200 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1298 |
1602 |
1.8e-120 |
PFAM |
|
low complexity region
|
1728 |
1742 |
N/A |
INTRINSIC |
|
low complexity region
|
1757 |
1771 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094609
|
| SMART Domains |
Protein: ENSMUSP00000092192
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
93 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
113 |
364 |
3.6e-36 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094610
|
| SMART Domains |
Protein: ENSMUSP00000092193
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NCKAP5
|
1 |
101 |
8.8e-42 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000112583
AA Change: P939L
PolyPhen 2
Score 0.985 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000108202
Gene: ENSMUSG00000049690
AA Change: P939L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
93 |
N/A |
INTRINSIC |
|
coiled coil region
|
176 |
254 |
N/A |
INTRINSIC |
|
low complexity region
|
301 |
324 |
N/A |
INTRINSIC |
|
low complexity region
|
453 |
464 |
N/A |
INTRINSIC |
|
low complexity region
|
887 |
903 |
N/A |
INTRINSIC |
|
low complexity region
|
1082 |
1103 |
N/A |
INTRINSIC |
|
low complexity region
|
1202 |
1217 |
N/A |
INTRINSIC |
|
low complexity region
|
1313 |
1332 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1431 |
1733 |
5.3e-119 |
PFAM |
|
low complexity region
|
1860 |
1874 |
N/A |
INTRINSIC |
|
low complexity region
|
1889 |
1903 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000161954
AA Change: P871L
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000125624
Gene: ENSMUSG00000049690
AA Change: P871L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
25 |
N/A |
INTRINSIC |
|
coiled coil region
|
108 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
233 |
256 |
N/A |
INTRINSIC |
|
low complexity region
|
385 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
1014 |
1035 |
N/A |
INTRINSIC |
|
low complexity region
|
1134 |
1149 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1264 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1362 |
1666 |
2.1e-120 |
PFAM |
|
low complexity region
|
1792 |
1806 |
N/A |
INTRINSIC |
|
low complexity region
|
1821 |
1835 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162877
|
| SMART Domains |
Protein: ENSMUSP00000124748
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NCKAP5
|
9 |
296 |
6e-36 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 99.3%
- 20x: 98.4%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(1) : Gene trapped(1) |
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam5 |
T |
C |
8: 25,301,068 (GRCm39) |
T221A |
probably benign |
Het |
| Adamts12 |
G |
A |
15: 11,310,628 (GRCm39) |
V962I |
probably damaging |
Het |
| Ano3 |
T |
A |
2: 110,488,640 (GRCm39) |
I931F |
probably damaging |
Het |
| Anxa2r2 |
T |
A |
13: 120,488,200 (GRCm39) |
E116D |
possibly damaging |
Het |
| Arih1 |
T |
G |
9: 59,300,581 (GRCm39) |
D555A |
possibly damaging |
Het |
| Arsg |
A |
G |
11: 109,381,452 (GRCm39) |
D65G |
probably damaging |
Het |
| Atp8b3 |
G |
A |
10: 80,364,407 (GRCm39) |
T567I |
probably damaging |
Het |
| Camkk2 |
G |
C |
5: 122,872,182 (GRCm39) |
R575G |
probably benign |
Het |
| Ccdc168 |
G |
T |
1: 44,095,824 (GRCm39) |
S1758Y |
possibly damaging |
Het |
| Ccdc88b |
G |
T |
19: 6,831,461 (GRCm39) |
L494M |
probably damaging |
Het |
| Cdc7 |
A |
G |
5: 107,123,405 (GRCm39) |
K317E |
possibly damaging |
Het |
| Cfh |
A |
G |
1: 140,090,687 (GRCm39) |
|
probably null |
Het |
| Cp |
T |
G |
3: 20,043,335 (GRCm39) |
V1041G |
possibly damaging |
Het |
| Cpeb3 |
A |
G |
19: 37,151,926 (GRCm39) |
V150A |
probably benign |
Het |
| Cyp7a1 |
T |
A |
4: 6,269,216 (GRCm39) |
E352V |
probably damaging |
Het |
| Dnah9 |
T |
A |
11: 65,976,290 (GRCm39) |
H1253L |
possibly damaging |
Het |
| Dsg3 |
T |
C |
18: 20,672,761 (GRCm39) |
S811P |
possibly damaging |
Het |
| Efcab5 |
A |
T |
11: 77,007,022 (GRCm39) |
Y867* |
probably null |
Het |
| Eif2ak1 |
A |
G |
5: 143,819,031 (GRCm39) |
T231A |
probably damaging |
Het |
| Eif2ak4 |
T |
A |
2: 118,247,730 (GRCm39) |
C256S |
probably benign |
Het |
| Eif5b |
A |
G |
1: 38,090,241 (GRCm39) |
N1140S |
possibly damaging |
Het |
| Etnppl |
A |
T |
3: 130,414,002 (GRCm39) |
M34L |
probably benign |
Het |
| Fcrl5 |
T |
G |
3: 87,364,469 (GRCm39) |
C549W |
possibly damaging |
Het |
| Fhod1 |
G |
A |
8: 106,058,323 (GRCm39) |
A811V |
probably damaging |
Het |
| Flcn |
C |
T |
11: 59,692,980 (GRCm39) |
S198N |
probably benign |
Het |
| Fndc1 |
T |
A |
17: 7,991,929 (GRCm39) |
H589L |
unknown |
Het |
| Gm8108 |
G |
T |
14: 4,110,527 (GRCm38) |
|
probably benign |
Het |
| Hcn4 |
C |
T |
9: 58,730,996 (GRCm39) |
R68W |
unknown |
Het |
| Igfn1 |
A |
G |
1: 135,926,336 (GRCm39) |
L38P |
possibly damaging |
Het |
| Il1r1 |
A |
G |
1: 40,349,496 (GRCm39) |
T351A |
probably benign |
Het |
| Ildr2 |
T |
C |
1: 166,096,889 (GRCm39) |
L36P |
probably damaging |
Het |
| Itgb1bp1 |
C |
T |
12: 21,324,876 (GRCm39) |
C60Y |
probably damaging |
Het |
| Jrk |
A |
G |
15: 74,579,225 (GRCm39) |
L20P |
probably damaging |
Het |
| Kif5c |
C |
T |
2: 49,584,859 (GRCm39) |
A194V |
probably damaging |
Het |
| Lrp4 |
C |
T |
2: 91,316,116 (GRCm39) |
L745F |
probably damaging |
Het |
| Ly9 |
A |
T |
1: 171,428,722 (GRCm39) |
D299E |
possibly damaging |
Het |
| Mfsd1 |
C |
T |
3: 67,499,910 (GRCm39) |
T185I |
possibly damaging |
Het |
| Mprip |
A |
G |
11: 59,656,348 (GRCm39) |
Y808C |
probably damaging |
Het |
| Mrps2 |
C |
A |
2: 28,359,594 (GRCm39) |
H150Q |
possibly damaging |
Het |
| Mtcl3 |
A |
T |
10: 29,024,398 (GRCm39) |
D438V |
probably damaging |
Het |
| Mturn |
A |
T |
6: 54,665,989 (GRCm39) |
|
probably null |
Het |
| Myo5a |
T |
C |
9: 75,091,965 (GRCm39) |
S1205P |
probably damaging |
Het |
| Ndst3 |
T |
A |
3: 123,421,631 (GRCm39) |
I401F |
probably benign |
Het |
| Nek4 |
G |
A |
14: 30,709,114 (GRCm39) |
V723M |
possibly damaging |
Het |
| Nfe2l2 |
A |
G |
2: 75,506,667 (GRCm39) |
S478P |
probably damaging |
Het |
| Nol6 |
T |
C |
4: 41,123,538 (GRCm39) |
Y70C |
probably damaging |
Het |
| Nup88 |
T |
C |
11: 70,860,497 (GRCm39) |
E94G |
probably benign |
Het |
| Oas1h |
A |
T |
5: 121,005,088 (GRCm39) |
N179Y |
probably damaging |
Het |
| Or1o11 |
T |
G |
17: 37,756,595 (GRCm39) |
V61G |
probably benign |
Het |
| Or8b39 |
T |
A |
9: 37,996,353 (GRCm39) |
S74T |
probably benign |
Het |
| Otof |
T |
C |
5: 30,540,998 (GRCm39) |
D847G |
probably damaging |
Het |
| Pak1 |
C |
A |
7: 97,547,842 (GRCm39) |
D331E |
possibly damaging |
Het |
| Pkd1l3 |
T |
C |
8: 110,373,555 (GRCm39) |
W1374R |
probably benign |
Het |
| Pkdrej |
G |
T |
15: 85,704,871 (GRCm39) |
T355K |
possibly damaging |
Het |
| Pramel27 |
A |
G |
4: 143,579,892 (GRCm39) |
*492W |
probably null |
Het |
| Prkcd |
A |
T |
14: 30,320,800 (GRCm39) |
F607I |
possibly damaging |
Het |
| Prrc2c |
A |
G |
1: 162,535,435 (GRCm39) |
S775P |
unknown |
Het |
| Prss16 |
G |
T |
13: 22,192,504 (GRCm39) |
H154N |
possibly damaging |
Het |
| Psme2b |
T |
C |
11: 48,836,779 (GRCm39) |
D56G |
possibly damaging |
Het |
| Rapsn |
C |
T |
2: 90,875,823 (GRCm39) |
P400L |
probably damaging |
Het |
| Rptn |
A |
G |
3: 93,304,761 (GRCm39) |
D698G |
possibly damaging |
Het |
| Rragc |
T |
C |
4: 123,818,658 (GRCm39) |
V291A |
possibly damaging |
Het |
| Rras2 |
A |
G |
7: 113,716,629 (GRCm39) |
|
probably null |
Het |
| Rsf1 |
GGCG |
GGCGACGGCCGCG |
7: 97,229,113 (GRCm39) |
|
probably benign |
Het |
| Scyl2 |
A |
C |
10: 89,476,794 (GRCm39) |
M777R |
probably benign |
Het |
| Serhl |
G |
T |
15: 82,998,597 (GRCm39) |
V235L |
probably benign |
Het |
| Sh2b3 |
T |
C |
5: 121,955,874 (GRCm39) |
Y536C |
probably damaging |
Het |
| Sh3pxd2a |
T |
C |
19: 47,257,093 (GRCm39) |
M570V |
probably benign |
Het |
| Slamf8 |
C |
T |
1: 172,411,800 (GRCm39) |
V232M |
probably benign |
Het |
| Slc6a21 |
T |
A |
7: 44,929,941 (GRCm39) |
L143Q |
probably damaging |
Het |
| Snx9 |
T |
A |
17: 5,949,670 (GRCm39) |
D123E |
probably benign |
Het |
| Spopfm2 |
G |
A |
3: 94,083,155 (GRCm39) |
H219Y |
probably damaging |
Het |
| Supt6 |
C |
A |
11: 78,108,767 (GRCm39) |
R1178L |
probably damaging |
Het |
| Sycp2 |
T |
G |
2: 178,025,304 (GRCm39) |
E379D |
probably damaging |
Het |
| Tekt2 |
C |
T |
4: 126,217,444 (GRCm39) |
R207H |
probably damaging |
Het |
| Tg |
A |
G |
15: 66,719,008 (GRCm39) |
M2655V |
possibly damaging |
Het |
| Tiam2 |
C |
T |
17: 3,561,440 (GRCm39) |
T1335I |
probably benign |
Het |
| Tmem154 |
T |
A |
3: 84,573,693 (GRCm39) |
L12Q |
possibly damaging |
Het |
| Trpv3 |
A |
T |
11: 73,174,499 (GRCm39) |
I289F |
possibly damaging |
Het |
| Tubgcp3 |
A |
G |
8: 12,699,758 (GRCm39) |
L365P |
probably damaging |
Het |
| Tulp4 |
T |
C |
17: 6,291,480 (GRCm39) |
|
probably null |
Het |
| Tyr |
A |
G |
7: 87,142,072 (GRCm39) |
S163P |
possibly damaging |
Het |
| Usp42 |
A |
T |
5: 143,713,533 (GRCm39) |
|
probably null |
Het |
| Vmn2r94 |
A |
G |
17: 18,463,989 (GRCm39) |
M767T |
probably benign |
Het |
| Wasl |
A |
G |
6: 24,619,533 (GRCm39) |
V329A |
unknown |
Het |
| Wdr62 |
T |
A |
7: 29,953,466 (GRCm39) |
M635L |
possibly damaging |
Het |
| Wee1 |
G |
T |
7: 109,721,722 (GRCm39) |
E56* |
probably null |
Het |
| Zc3h12c |
C |
T |
9: 52,055,231 (GRCm39) |
G193S |
probably damaging |
Het |
| Zfp236 |
T |
A |
18: 82,637,008 (GRCm39) |
Q1426L |
possibly damaging |
Het |
| Zfp74 |
T |
C |
7: 29,634,751 (GRCm39) |
Y319C |
probably damaging |
Het |
|
| Other mutations in Nckap5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00833:Nckap5
|
APN |
1 |
125,954,889 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00956:Nckap5
|
APN |
1 |
125,952,755 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01414:Nckap5
|
APN |
1 |
126,456,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01482:Nckap5
|
APN |
1 |
125,950,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01508:Nckap5
|
APN |
1 |
125,953,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02071:Nckap5
|
APN |
1 |
125,909,305 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02129:Nckap5
|
APN |
1 |
125,955,432 (GRCm39) |
nonsense |
probably null |
|
|
IGL02821:Nckap5
|
APN |
1 |
125,955,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03174:Nckap5
|
APN |
1 |
125,909,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
F5493:Nckap5
|
UTSW |
1 |
125,953,564 (GRCm39) |
missense |
probably benign |
|
|
G5030:Nckap5
|
UTSW |
1 |
125,953,591 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0033:Nckap5
|
UTSW |
1 |
125,867,979 (GRCm39) |
intron |
probably benign |
|
|
R0164:Nckap5
|
UTSW |
1 |
125,952,144 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0164:Nckap5
|
UTSW |
1 |
125,952,144 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0349:Nckap5
|
UTSW |
1 |
125,954,171 (GRCm39) |
missense |
probably benign |
|
|
R0482:Nckap5
|
UTSW |
1 |
125,954,102 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0508:Nckap5
|
UTSW |
1 |
125,909,121 (GRCm39) |
splice site |
probably null |
|
|
R0541:Nckap5
|
UTSW |
1 |
126,623,459 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R0609:Nckap5
|
UTSW |
1 |
125,955,025 (GRCm39) |
nonsense |
probably null |
|
|
R0701:Nckap5
|
UTSW |
1 |
125,953,094 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0782:Nckap5
|
UTSW |
1 |
125,909,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1389:Nckap5
|
UTSW |
1 |
125,954,447 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1401:Nckap5
|
UTSW |
1 |
125,942,398 (GRCm39) |
splice site |
probably benign |
|
|
R1436:Nckap5
|
UTSW |
1 |
125,953,798 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1506:Nckap5
|
UTSW |
1 |
125,953,650 (GRCm39) |
nonsense |
probably null |
|
|
R1528:Nckap5
|
UTSW |
1 |
125,952,659 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1942:Nckap5
|
UTSW |
1 |
125,952,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1968:Nckap5
|
UTSW |
1 |
125,942,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2055:Nckap5
|
UTSW |
1 |
125,954,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2105:Nckap5
|
UTSW |
1 |
125,954,255 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2214:Nckap5
|
UTSW |
1 |
125,953,487 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R2311:Nckap5
|
UTSW |
1 |
126,456,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2403:Nckap5
|
UTSW |
1 |
125,955,146 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2430:Nckap5
|
UTSW |
1 |
125,842,494 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2914:Nckap5
|
UTSW |
1 |
125,954,274 (GRCm39) |
splice site |
probably null |
|
|
R3782:Nckap5
|
UTSW |
1 |
125,952,811 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4133:Nckap5
|
UTSW |
1 |
126,150,443 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4249:Nckap5
|
UTSW |
1 |
125,955,376 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4448:Nckap5
|
UTSW |
1 |
125,953,463 (GRCm39) |
nonsense |
probably null |
|
|
R4456:Nckap5
|
UTSW |
1 |
125,842,472 (GRCm39) |
unclassified |
probably benign |
|
|
R4682:Nckap5
|
UTSW |
1 |
126,030,279 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4817:Nckap5
|
UTSW |
1 |
125,954,952 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4907:Nckap5
|
UTSW |
1 |
125,953,889 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4908:Nckap5
|
UTSW |
1 |
125,955,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Nckap5
|
UTSW |
1 |
125,954,765 (GRCm39) |
nonsense |
probably null |
|
|
R4926:Nckap5
|
UTSW |
1 |
126,456,378 (GRCm39) |
intron |
probably benign |
|
|
R5032:Nckap5
|
UTSW |
1 |
125,904,786 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R5133:Nckap5
|
UTSW |
1 |
125,961,697 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5197:Nckap5
|
UTSW |
1 |
126,150,410 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5238:Nckap5
|
UTSW |
1 |
125,955,461 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5257:Nckap5
|
UTSW |
1 |
125,952,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5277:Nckap5
|
UTSW |
1 |
125,954,277 (GRCm39) |
nonsense |
probably null |
|
|
R5512:Nckap5
|
UTSW |
1 |
125,955,481 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5700:Nckap5
|
UTSW |
1 |
125,904,662 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5789:Nckap5
|
UTSW |
1 |
125,955,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6029:Nckap5
|
UTSW |
1 |
125,953,523 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6249:Nckap5
|
UTSW |
1 |
125,952,667 (GRCm39) |
missense |
probably benign |
|
|
R6292:Nckap5
|
UTSW |
1 |
125,842,752 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6521:Nckap5
|
UTSW |
1 |
126,309,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Nckap5
|
UTSW |
1 |
125,950,931 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7017:Nckap5
|
UTSW |
1 |
126,030,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7018:Nckap5
|
UTSW |
1 |
125,952,785 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7054:Nckap5
|
UTSW |
1 |
126,186,449 (GRCm39) |
splice site |
probably null |
|
|
R7204:Nckap5
|
UTSW |
1 |
125,954,104 (GRCm39) |
missense |
probably benign |
|
|
R7336:Nckap5
|
UTSW |
1 |
125,953,786 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7544:Nckap5
|
UTSW |
1 |
125,953,948 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7590:Nckap5
|
UTSW |
1 |
125,954,270 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7684:Nckap5
|
UTSW |
1 |
125,954,594 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7749:Nckap5
|
UTSW |
1 |
125,952,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7773:Nckap5
|
UTSW |
1 |
125,954,581 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7813:Nckap5
|
UTSW |
1 |
125,953,163 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7970:Nckap5
|
UTSW |
1 |
125,952,758 (GRCm39) |
nonsense |
probably null |
|
|
R7992:Nckap5
|
UTSW |
1 |
125,954,547 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8278:Nckap5
|
UTSW |
1 |
125,955,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8373:Nckap5
|
UTSW |
1 |
125,954,032 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8414:Nckap5
|
UTSW |
1 |
125,942,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8755:Nckap5
|
UTSW |
1 |
125,954,279 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8845:Nckap5
|
UTSW |
1 |
125,909,423 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9016:Nckap5
|
UTSW |
1 |
126,623,491 (GRCm39) |
start codon destroyed |
probably null |
0.01 |
|
R9209:Nckap5
|
UTSW |
1 |
125,867,928 (GRCm39) |
missense |
unknown |
|
|
R9214:Nckap5
|
UTSW |
1 |
125,942,376 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9300:Nckap5
|
UTSW |
1 |
125,909,423 (GRCm39) |
nonsense |
probably null |
|
|
R9464:Nckap5
|
UTSW |
1 |
125,952,494 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9572:Nckap5
|
UTSW |
1 |
125,955,454 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9721:Nckap5
|
UTSW |
1 |
125,955,017 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1088:Nckap5
|
UTSW |
1 |
125,952,569 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
Z1176:Nckap5
|
UTSW |
1 |
126,456,418 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1177:Nckap5
|
UTSW |
1 |
126,150,396 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCGTCACAGCAAATGGACTG -3'
(R):5'- TCCAGTCACGGCATCTCATG -3'
Sequencing Primer
(F):5'- CAAATGGACTGGAGGCTATGTGTTC -3'
(R):5'- AAATGAGGTCCAATGGCTGTGTC -3'
|
| Posted On |
2022-11-14 |
Incidental Mutation