Incidental Mutation 'R9749:Adamtsl3'
| ID |
732410 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adamtsl3
|
| Ensembl Gene |
ENSMUSG00000070469 |
| Gene Name |
ADAMTS-like 3 |
| Synonyms |
9230119C12Rik, punctin-2 |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9749 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
81984902-82263658 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 82099394 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Glycine
at position 183
(S183G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133637
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000173287]
[ENSMUST00000173828]
|
| AlphaFold |
G3UXC7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000173287
AA Change: S183G
PolyPhen 2
Score 0.037 (Sensitivity: 0.94; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000133637
Gene: ENSMUSG00000070469
AA Change: S183G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
38 |
N/A |
INTRINSIC |
|
TSP1
|
90 |
136 |
6.43e-8 |
SMART |
|
TSP1
|
355 |
414 |
1.59e-1 |
SMART |
|
TSP1
|
433 |
492 |
3.72e-4 |
SMART |
|
TSP1
|
494 |
547 |
4.28e-4 |
SMART |
|
TSP1
|
579 |
638 |
1.85e-2 |
SMART |
|
TSP1
|
660 |
717 |
1.75e-2 |
SMART |
|
TSP1
|
719 |
773 |
3.45e-8 |
SMART |
|
TSP1
|
775 |
833 |
3.67e-3 |
SMART |
|
TSP1
|
836 |
894 |
8.99e-2 |
SMART |
|
IGc2
|
938 |
1002 |
7.59e-4 |
SMART |
|
IG
|
1213 |
1296 |
4.87e0 |
SMART |
|
IGc2
|
1326 |
1388 |
1.01e-13 |
SMART |
|
TSP1
|
1441 |
1498 |
1.95e-2 |
SMART |
|
TSP1
|
1500 |
1559 |
6.76e-2 |
SMART |
|
TSP1
|
1616 |
1666 |
3.84e-1 |
SMART |
|
Pfam:PLAC
|
1674 |
1704 |
2.4e-11 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000173828
|
| SMART Domains |
Protein: ENSMUSP00000133337
Gene: ENSMUSG00000070469
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
Blast:IG
|
22 |
79 |
1e-26 |
BLAST |
|
SCOP:d1biha4
|
27 |
77 |
2e-5 |
SMART |
|
IG
|
283 |
366 |
4.87e0 |
SMART |
|
IGc2
|
396 |
458 |
1.01e-13 |
SMART |
|
TSP1
|
511 |
568 |
1.95e-2 |
SMART |
|
TSP1
|
570 |
629 |
6.76e-2 |
SMART |
|
TSP1
|
686 |
736 |
3.84e-1 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.8%
- 10x: 99.3%
- 20x: 98.3%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(10) : Targeted(7) Gene trapped(2) Spontaneous(1)
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933427D14Rik |
T |
A |
11: 72,080,521 (GRCm39) |
I382F |
possibly damaging |
Het |
| Adamtsl4 |
T |
C |
3: 95,591,457 (GRCm39) |
H170R |
probably benign |
Het |
| Adcy2 |
T |
C |
13: 68,773,974 (GRCm39) |
D1023G |
probably damaging |
Het |
| Agrn |
C |
A |
4: 156,258,114 (GRCm39) |
V1083F |
probably benign |
Het |
| Arhgap21 |
T |
C |
2: 20,854,026 (GRCm39) |
T1789A |
probably benign |
Het |
| Atr |
T |
C |
9: 95,819,703 (GRCm39) |
|
probably null |
Het |
| Bcl2l13 |
T |
C |
6: 120,842,633 (GRCm39) |
S109P |
possibly damaging |
Het |
| Bik |
A |
T |
15: 83,425,540 (GRCm39) |
T14S |
possibly damaging |
Het |
| Car7 |
A |
G |
8: 105,275,054 (GRCm39) |
D164G |
probably damaging |
Het |
| Cat |
T |
A |
2: 103,285,445 (GRCm39) |
K499M |
probably benign |
Het |
| Ccar2 |
T |
A |
14: 70,388,728 (GRCm39) |
Q161L |
probably benign |
Het |
| Cd109 |
T |
G |
9: 78,592,166 (GRCm39) |
V760G |
probably damaging |
Het |
| Cep350 |
A |
T |
1: 155,828,985 (GRCm39) |
H246Q |
probably benign |
Het |
| Cfap91 |
A |
G |
16: 38,128,487 (GRCm39) |
I496T |
probably damaging |
Het |
| Chst13 |
T |
C |
6: 90,295,251 (GRCm39) |
D54G |
probably damaging |
Het |
| Cilk1 |
T |
A |
9: 78,060,999 (GRCm39) |
V215E |
probably damaging |
Het |
| Col4a4 |
A |
G |
1: 82,463,353 (GRCm39) |
S1046P |
unknown |
Het |
| Col6a5 |
T |
C |
9: 105,739,190 (GRCm39) |
Q2581R |
probably damaging |
Het |
| Cox5b-ps |
G |
A |
13: 21,685,515 (GRCm39) |
A25V |
probably benign |
Het |
| Csmd2 |
A |
T |
4: 128,389,921 (GRCm39) |
I2219F |
|
Het |
| Cux2 |
G |
A |
5: 122,007,780 (GRCm39) |
S627L |
possibly damaging |
Het |
| Cyp2a22 |
A |
T |
7: 26,638,715 (GRCm39) |
W24R |
probably null |
Het |
| Dhrs7c |
A |
T |
11: 67,702,479 (GRCm39) |
T156S |
probably damaging |
Het |
| Dnah9 |
A |
G |
11: 65,986,202 (GRCm39) |
V1144A |
probably damaging |
Het |
| Folh1 |
T |
C |
7: 86,368,908 (GRCm39) |
T740A |
probably damaging |
Het |
| Foxo4 |
G |
A |
X: 100,301,955 (GRCm39) |
S209N |
probably benign |
Het |
| Gm10300 |
A |
G |
4: 131,802,029 (GRCm39) |
T8A |
unknown |
Het |
| Gns |
T |
A |
10: 121,214,057 (GRCm39) |
I244N |
probably benign |
Het |
| Gsdmd |
A |
G |
15: 75,735,411 (GRCm39) |
K52E |
probably damaging |
Het |
| H1f0 |
A |
G |
15: 78,913,217 (GRCm39) |
D99G |
probably benign |
Het |
| Hapln4 |
T |
C |
8: 70,539,724 (GRCm39) |
Y252H |
probably damaging |
Het |
| Hmcn1 |
A |
C |
1: 150,632,339 (GRCm39) |
I866S |
possibly damaging |
Het |
| Hrnr |
C |
T |
3: 93,231,384 (GRCm39) |
R541C |
unknown |
Het |
| Igkv4-57-1 |
A |
G |
6: 69,521,408 (GRCm39) |
I98T |
probably damaging |
Het |
| Itih3 |
T |
A |
14: 30,641,279 (GRCm39) |
D253V |
probably damaging |
Het |
| Kansl1l |
T |
A |
1: 66,760,970 (GRCm39) |
E869D |
probably damaging |
Het |
| Kif13a |
T |
C |
13: 46,914,227 (GRCm39) |
Q502R |
probably damaging |
Het |
| Lama5 |
T |
A |
2: 179,825,433 (GRCm39) |
Q2447L |
probably benign |
Het |
| Lcn6 |
A |
T |
2: 25,570,034 (GRCm39) |
M1L |
probably benign |
Het |
| Lrrtm1 |
T |
C |
6: 77,220,855 (GRCm39) |
V104A |
probably damaging |
Het |
| Map3k13 |
T |
C |
16: 21,740,581 (GRCm39) |
L636P |
probably benign |
Het |
| Melk |
T |
A |
4: 44,307,067 (GRCm39) |
H74Q |
possibly damaging |
Het |
| Mixl1 |
A |
T |
1: 180,522,311 (GRCm39) |
M190K |
probably benign |
Het |
| Mttp |
A |
G |
3: 137,830,989 (GRCm39) |
S27P |
probably damaging |
Het |
| Myh6 |
T |
C |
14: 55,190,943 (GRCm39) |
I911V |
probably damaging |
Het |
| Ncapd3 |
T |
A |
9: 26,956,873 (GRCm39) |
I262N |
probably benign |
Het |
| Ncapg2 |
C |
A |
12: 116,411,368 (GRCm39) |
S1051* |
probably null |
Het |
| Nckap1 |
G |
A |
2: 80,401,568 (GRCm39) |
Q39* |
probably null |
Het |
| Nemp1 |
A |
G |
10: 127,524,198 (GRCm39) |
D76G |
probably benign |
Het |
| Or12e10 |
A |
C |
2: 87,640,202 (GRCm39) |
K13Q |
probably benign |
Het |
| Or2a20 |
G |
A |
6: 43,194,258 (GRCm39) |
W137* |
probably null |
Het |
| Or2l13 |
A |
T |
16: 19,306,113 (GRCm39) |
H175L |
possibly damaging |
Het |
| Or4a2 |
T |
A |
2: 89,248,662 (GRCm39) |
I32F |
possibly damaging |
Het |
| Or8k36-ps1 |
T |
C |
2: 86,437,909 (GRCm39) |
E2G |
probably benign |
Het |
| Osbpl5 |
C |
A |
7: 143,249,308 (GRCm39) |
V578L |
probably benign |
Het |
| Peg10 |
CCACATCAGGATCCACATCAGGATGCACATCAGCATCAGGATCCCCATCAGGATGCACATCAGGATCCACATCAGGATGCACATCAG |
CCACATCAGGATCCACATCAGGATGCACATCAG |
6: 4,756,398 (GRCm39) |
|
probably benign |
Het |
| Rabl3 |
A |
G |
16: 37,377,190 (GRCm39) |
D49G |
possibly damaging |
Het |
| Rngtt |
A |
G |
4: 33,368,618 (GRCm39) |
I384V |
possibly damaging |
Het |
| Robo1 |
T |
C |
16: 72,105,257 (GRCm39) |
|
probably benign |
Het |
| Rtcb |
C |
A |
10: 85,785,453 (GRCm39) |
R125L |
probably damaging |
Het |
| Rtn4rl2 |
C |
A |
2: 84,702,954 (GRCm39) |
R206L |
probably damaging |
Het |
| Sbk2 |
A |
T |
7: 4,960,333 (GRCm39) |
I279N |
probably benign |
Het |
| Scaf1 |
A |
G |
7: 44,656,576 (GRCm39) |
S768P |
unknown |
Het |
| Slc6a9 |
A |
G |
4: 117,721,198 (GRCm39) |
H316R |
probably damaging |
Het |
| Son |
CATGGACTCCCAGATGTTAGCAACTAGCTCTATGGACTCCCAGATGTTAGCAACTAGCTCTATGGACTCCCAGATGTTAGCAACCAGCAGTATGGACTCCCAGATGTTAGCAACCAGCAGTATGGACTCCCAGATGTTAGCAACCAGCTCCATGGACTCCCAGATGTTAGCAAC |
CATGGACTCCCAGATGTTAGCAACTAGCTCTATGGACTCCCAGATGTTAGCAACCAGCAGTATGGACTCCCAGATGTTAGCAACCAGCAGTATGGACTCCCAGATGTTAGCAACCAGCTCCATGGACTCCCAGATGTTAGCAAC |
16: 91,453,579 (GRCm39) |
|
probably benign |
Het |
| Tas2r136 |
G |
T |
6: 132,755,106 (GRCm39) |
T7K |
probably damaging |
Het |
| Tbc1d9 |
T |
A |
8: 83,968,339 (GRCm39) |
|
probably null |
Het |
| Tekt2 |
C |
T |
4: 126,217,444 (GRCm39) |
R207H |
probably damaging |
Het |
| Tmem40 |
T |
C |
6: 115,719,306 (GRCm39) |
D53G |
probably benign |
Het |
| Tram1 |
A |
T |
1: 13,640,238 (GRCm39) |
V272D |
possibly damaging |
Het |
| Trpc4 |
G |
A |
3: 54,102,302 (GRCm39) |
D67N |
probably damaging |
Het |
| Ttc6 |
A |
T |
12: 57,701,559 (GRCm39) |
T591S |
probably benign |
Het |
| Ube2g1 |
A |
T |
11: 72,570,199 (GRCm39) |
E144V |
probably benign |
Het |
| Unc80 |
A |
G |
1: 66,544,179 (GRCm39) |
D434G |
probably damaging |
Het |
| Vmn1r168 |
C |
A |
7: 23,240,237 (GRCm39) |
N31K |
probably damaging |
Het |
| Vmn1r79 |
A |
T |
7: 11,910,450 (GRCm39) |
T111S |
probably damaging |
Het |
| Vmn2r118 |
C |
T |
17: 55,915,415 (GRCm39) |
|
probably null |
Het |
| Vps35l |
C |
A |
7: 118,352,107 (GRCm39) |
D195E |
probably benign |
Het |
| Yy1 |
A |
G |
12: 108,772,417 (GRCm39) |
D231G |
possibly damaging |
Het |
| Zfp748 |
A |
G |
13: 67,690,573 (GRCm39) |
V229A |
probably benign |
Het |
|
| Other mutations in Adamtsl3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01549:Adamtsl3
|
APN |
7 |
82,261,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01936:Adamtsl3
|
APN |
7 |
82,244,579 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02819:Adamtsl3
|
APN |
7 |
82,223,329 (GRCm39) |
missense |
probably damaging |
0.99 |
|
P0012:Adamtsl3
|
UTSW |
7 |
82,223,465 (GRCm39) |
missense |
probably benign |
0.27 |
|
R0096:Adamtsl3
|
UTSW |
7 |
82,114,907 (GRCm39) |
intron |
probably benign |
|
|
R0096:Adamtsl3
|
UTSW |
7 |
82,114,907 (GRCm39) |
intron |
probably benign |
|
|
R0180:Adamtsl3
|
UTSW |
7 |
82,225,198 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0270:Adamtsl3
|
UTSW |
7 |
82,206,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0295:Adamtsl3
|
UTSW |
7 |
82,197,213 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0329:Adamtsl3
|
UTSW |
7 |
82,171,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0330:Adamtsl3
|
UTSW |
7 |
82,171,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0548:Adamtsl3
|
UTSW |
7 |
82,178,191 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0611:Adamtsl3
|
UTSW |
7 |
82,178,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0671:Adamtsl3
|
UTSW |
7 |
82,172,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0711:Adamtsl3
|
UTSW |
7 |
82,114,907 (GRCm39) |
intron |
probably benign |
|
|
R0845:Adamtsl3
|
UTSW |
7 |
82,225,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1119:Adamtsl3
|
UTSW |
7 |
82,189,525 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1458:Adamtsl3
|
UTSW |
7 |
82,172,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1644:Adamtsl3
|
UTSW |
7 |
82,099,298 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1691:Adamtsl3
|
UTSW |
7 |
82,148,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1838:Adamtsl3
|
UTSW |
7 |
82,142,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2131:Adamtsl3
|
UTSW |
7 |
82,227,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2245:Adamtsl3
|
UTSW |
7 |
82,099,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2274:Adamtsl3
|
UTSW |
7 |
82,255,766 (GRCm39) |
missense |
probably benign |
0.37 |
|
R2275:Adamtsl3
|
UTSW |
7 |
82,255,766 (GRCm39) |
missense |
probably benign |
0.37 |
|
R2448:Adamtsl3
|
UTSW |
7 |
82,148,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3725:Adamtsl3
|
UTSW |
7 |
82,261,612 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R3757:Adamtsl3
|
UTSW |
7 |
81,986,415 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3821:Adamtsl3
|
UTSW |
7 |
82,255,687 (GRCm39) |
splice site |
probably benign |
|
|
R4618:Adamtsl3
|
UTSW |
7 |
82,255,728 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4842:Adamtsl3
|
UTSW |
7 |
82,178,069 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4887:Adamtsl3
|
UTSW |
7 |
82,223,822 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4888:Adamtsl3
|
UTSW |
7 |
82,223,822 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4925:Adamtsl3
|
UTSW |
7 |
82,251,507 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4960:Adamtsl3
|
UTSW |
7 |
82,216,185 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5026:Adamtsl3
|
UTSW |
7 |
82,225,262 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5152:Adamtsl3
|
UTSW |
7 |
82,223,752 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5198:Adamtsl3
|
UTSW |
7 |
82,261,006 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5244:Adamtsl3
|
UTSW |
7 |
82,247,277 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5281:Adamtsl3
|
UTSW |
7 |
82,178,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5323:Adamtsl3
|
UTSW |
7 |
82,206,269 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5523:Adamtsl3
|
UTSW |
7 |
82,223,650 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5602:Adamtsl3
|
UTSW |
7 |
82,206,447 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5638:Adamtsl3
|
UTSW |
7 |
82,260,958 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5682:Adamtsl3
|
UTSW |
7 |
82,255,758 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5782:Adamtsl3
|
UTSW |
7 |
82,189,494 (GRCm39) |
splice site |
probably null |
|
|
R5946:Adamtsl3
|
UTSW |
7 |
82,225,265 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6091:Adamtsl3
|
UTSW |
7 |
82,114,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6258:Adamtsl3
|
UTSW |
7 |
82,178,191 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6500:Adamtsl3
|
UTSW |
7 |
82,227,818 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6765:Adamtsl3
|
UTSW |
7 |
82,216,232 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6785:Adamtsl3
|
UTSW |
7 |
82,171,212 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6982:Adamtsl3
|
UTSW |
7 |
82,164,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7109:Adamtsl3
|
UTSW |
7 |
82,261,069 (GRCm39) |
missense |
|
|
|
R7341:Adamtsl3
|
UTSW |
7 |
82,206,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7402:Adamtsl3
|
UTSW |
7 |
82,227,825 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7506:Adamtsl3
|
UTSW |
7 |
82,164,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7549:Adamtsl3
|
UTSW |
7 |
82,223,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7575:Adamtsl3
|
UTSW |
7 |
82,223,756 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7592:Adamtsl3
|
UTSW |
7 |
81,986,459 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7617:Adamtsl3
|
UTSW |
7 |
82,206,054 (GRCm39) |
splice site |
probably null |
|
|
R7654:Adamtsl3
|
UTSW |
7 |
82,223,702 (GRCm39) |
missense |
probably benign |
|
|
R7721:Adamtsl3
|
UTSW |
7 |
82,255,728 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R7784:Adamtsl3
|
UTSW |
7 |
82,223,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7858:Adamtsl3
|
UTSW |
7 |
82,099,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8109:Adamtsl3
|
UTSW |
7 |
82,251,487 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8125:Adamtsl3
|
UTSW |
7 |
82,099,541 (GRCm39) |
splice site |
probably null |
|
|
R8211:Adamtsl3
|
UTSW |
7 |
82,172,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8348:Adamtsl3
|
UTSW |
7 |
82,253,007 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8360:Adamtsl3
|
UTSW |
7 |
82,197,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8448:Adamtsl3
|
UTSW |
7 |
82,253,007 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8465:Adamtsl3
|
UTSW |
7 |
82,247,330 (GRCm39) |
missense |
probably benign |
0.43 |
|
R8547:Adamtsl3
|
UTSW |
7 |
82,077,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8551:Adamtsl3
|
UTSW |
7 |
82,189,678 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8558:Adamtsl3
|
UTSW |
7 |
82,077,600 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R8709:Adamtsl3
|
UTSW |
7 |
82,077,642 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8722:Adamtsl3
|
UTSW |
7 |
82,244,745 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8930:Adamtsl3
|
UTSW |
7 |
82,261,069 (GRCm39) |
missense |
|
|
|
R8932:Adamtsl3
|
UTSW |
7 |
82,261,069 (GRCm39) |
missense |
|
|
|
R9131:Adamtsl3
|
UTSW |
7 |
82,244,722 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9169:Adamtsl3
|
UTSW |
7 |
82,223,188 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9272:Adamtsl3
|
UTSW |
7 |
82,189,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9276:Adamtsl3
|
UTSW |
7 |
82,206,710 (GRCm39) |
intron |
probably benign |
|
|
R9351:Adamtsl3
|
UTSW |
7 |
82,169,929 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9352:Adamtsl3
|
UTSW |
7 |
82,091,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9750:Adamtsl3
|
UTSW |
7 |
82,244,589 (GRCm39) |
missense |
probably benign |
0.11 |
|
RF005:Adamtsl3
|
UTSW |
7 |
82,261,603 (GRCm39) |
missense |
|
|
|
X0003:Adamtsl3
|
UTSW |
7 |
82,260,967 (GRCm39) |
nonsense |
probably null |
|
|
X0063:Adamtsl3
|
UTSW |
7 |
82,223,365 (GRCm39) |
missense |
probably benign |
0.25 |
|
Z1088:Adamtsl3
|
UTSW |
7 |
82,189,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Adamtsl3
|
UTSW |
7 |
82,148,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AACCTTCTGTTGACCCCATGG -3'
(R):5'- CTGGGGAATACATTTACACTGAAATGG -3'
Sequencing Primer
(F):5'- GCACATGCACATGGTTCC -3'
(R):5'- CTGAAATGGTCAAAACCTCTTTATCG -3'
|
| Posted On |
2022-11-14 |
Incidental Mutation