Incidental Mutation 'IGL01301:Zfp395'
ID73252
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zfp395
Ensembl Gene ENSMUSG00000034522
Gene Namezinc finger protein 395
SynonymsLOC380912, BC027382
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL01301
Quality Score
Status
Chromosome14
Chromosomal Location65358389-65398930 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to A at 65394751 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000064422 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000066994]
Predicted Effect probably null
Transcript: ENSMUST00000066994
SMART Domains Protein: ENSMUSP00000064422
Gene: ENSMUSG00000034522

DomainStartEndE-ValueType
Pfam:DUF4772 2 110 5.3e-31 PFAM
low complexity region 162 174 N/A INTRINSIC
low complexity region 208 234 N/A INTRINSIC
ZnF_C2H2 279 304 1.25e-1 SMART
low complexity region 356 367 N/A INTRINSIC
low complexity region 429 446 N/A INTRINSIC
c-clamp 478 508 1.88e-12 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000225512
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 44 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1600012H06Rik C T 17: 14,943,919 probably null Het
Acacb A T 5: 114,246,498 I2238L probably benign Het
Aldh1l2 T C 10: 83,522,846 Y95C probably damaging Het
Asxl2 A G 12: 3,501,425 T1056A probably damaging Het
B4galnt1 A G 10: 127,169,779 T250A possibly damaging Het
Cela3b A T 4: 137,423,843 probably null Het
Chst3 T C 10: 60,185,832 T398A probably damaging Het
Cngb3 A G 4: 19,425,625 T478A probably damaging Het
Cyp4a10 T C 4: 115,518,455 L45P probably damaging Het
Defb21 A G 2: 152,574,751 E49G possibly damaging Het
Dnajc1 T C 2: 18,308,834 T159A probably damaging Het
Dnmbp A G 19: 43,902,354 S325P probably benign Het
Fam91a1 T C 15: 58,442,871 F534L probably damaging Het
Fermt2 T C 14: 45,464,863 E488G probably damaging Het
Filip1 T C 9: 79,819,180 D719G possibly damaging Het
Gad1-ps A G 10: 99,445,151 noncoding transcript Het
Glra3 C A 8: 55,940,962 A36E probably benign Het
Gm9884 T A 1: 25,830,648 probably benign Het
Hectd2 T C 19: 36,569,370 probably benign Het
Hnrnpm C T 17: 33,669,168 probably null Het
Lrrk2 T A 15: 91,767,339 Y1733N probably damaging Het
Mindy1 T C 3: 95,288,390 L148P probably damaging Het
Mkrn2 C A 6: 115,611,789 Y164* probably null Het
Msra T C 14: 64,210,435 Y135C probably damaging Het
Ndst3 C T 3: 123,548,916 A749T probably damaging Het
Ngdn G T 14: 55,017,114 A41S probably benign Het
Nlrp12 A T 7: 3,240,092 S597T probably damaging Het
Olfr1451 A T 19: 12,999,417 I144F probably damaging Het
Pabpc6 A G 17: 9,667,970 S551P probably benign Het
Plekhg5 C T 4: 152,112,553 A752V probably benign Het
Prpf4b T C 13: 34,884,291 S368P probably benign Het
Pus7 A G 5: 23,746,424 probably null Het
Rad23b T C 4: 55,366,774 probably benign Het
Rgs13 T C 1: 144,171,414 probably benign Het
Sfpq T C 4: 127,026,760 probably benign Het
Slc9a9 T A 9: 95,055,459 S455T probably benign Het
Slco1a1 A G 6: 141,932,530 probably benign Het
Tmem26 A T 10: 68,778,606 N284Y probably damaging Het
Tmem87a T C 2: 120,380,769 I232V probably benign Het
Trpm2 A G 10: 77,923,984 L1106P probably damaging Het
Vmn1r18 T C 6: 57,389,667 probably benign Het
Zfp213 G T 17: 23,561,417 A43D probably benign Het
Zfp365 A G 10: 67,909,354 V198A probably damaging Het
Zfp618 G A 4: 63,132,826 V615M probably damaging Het
Other mutations in Zfp395
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01712:Zfp395 APN 14 65386387 missense probably damaging 0.98
IGL02885:Zfp395 APN 14 65395895 missense probably benign 0.05
R0243:Zfp395 UTSW 14 65386480 missense probably benign
R1540:Zfp395 UTSW 14 65393074 missense probably benign
R2005:Zfp395 UTSW 14 65388885 missense possibly damaging 0.87
R2108:Zfp395 UTSW 14 65393116 missense probably benign 0.24
R3499:Zfp395 UTSW 14 65391293 missense possibly damaging 0.87
R4790:Zfp395 UTSW 14 65386541 missense possibly damaging 0.74
R4790:Zfp395 UTSW 14 65393207 missense probably damaging 1.00
R6978:Zfp395 UTSW 14 65386433 missense probably benign 0.05
RF024:Zfp395 UTSW 14 65385425 missense unknown
Posted On2013-10-07