Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL01302:Vmn2r78'

73274

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r78

Ensembl Gene

ENSMUSG00000091962

Gene Name

vomeronasal 2, receptor 78

Synonyms

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.075) question?

Stock #

IGL01302

Quality Score

Status

Chromosome

Chromosomal Location

86915300-86955177 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 86915361 bp

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Valine at position 5 (I5V)

Ref Sequence

ENSEMBL: ENSMUSP00000126698 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000170835]

Predicted Effect

unknown
Transcript: ENSMUST00000170835
AA Change: I5V

SMART Domains

Protein: ENSMUSP00000126698
Gene: ENSMUSG00000091962
AA Change: I5V

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
Pfam:ANF_receptor	75	464	5.9e-31	PFAM
Pfam:NCD3G	507	559	8.1e-21	PFAM
Pfam:7tm_3	592	827	1e-52	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 44 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca13	T	A	11: 9,399,470		probably benign	Het
Abcb5	T	A	12: 118,918,200	D598V	probably damaging	Het
Adssl1	T	C	12: 112,634,736		probably benign	Het
Akap9	T	A	5: 3,970,711	S1141T	probably benign	Het
Avil	T	C	10: 127,017,034		probably null	Het
Avl9	C	A	6: 56,725,090	H77N	probably damaging	Het
Cacna1e	A	G	1: 154,443,907	V1349A	probably damaging	Het
Cdc23	A	C	18: 34,634,644	S483A	probably benign	Het
Cep192	C	T	18: 67,858,903	P1951S	probably benign	Het
Cp	A	G	3: 19,966,367	T175A	probably damaging	Het
Dubr	A	C	16: 50,732,635		noncoding transcript	Het
Eif4g2	G	T	7: 111,074,713	Q695K	possibly damaging	Het
Endod1	A	T	9: 14,357,239	S317T	possibly damaging	Het
Ep400	T	C	5: 110,742,048	T450A	probably benign	Het
Erc1	A	C	6: 119,722,303	V790G	probably damaging	Het
Fam222a	T	A	5: 114,594,453	L23Q	possibly damaging	Het
Fam35a	C	T	14: 34,259,727	V485I	probably benign	Het
Fancf	A	G	7: 51,861,287	V323A	probably benign	Het
Grik2	T	A	10: 49,244,330	Q621L	probably damaging	Het
Gsk3b	G	T	16: 38,220,018	R319L	probably benign	Het
Ikzf1	A	G	11: 11,768,923	Y297C	probably damaging	Het
Katnal2	T	C	18: 77,047,167		probably benign	Het
Lrba	G	T	3: 86,295,400	C289F	probably damaging	Het
Mos	T	C	4: 3,871,815		probably benign	Het
Mycn	T	C	12: 12,937,586	D270G	possibly damaging	Het
Olfr672	A	T	7: 104,996,721	M61K	probably damaging	Het
Olfr777	T	A	10: 129,268,523	I267F	probably benign	Het
Pclo	A	G	5: 14,675,999		probably benign	Het
Pgm2	A	G	4: 99,929,606	D14G	probably damaging	Het
Pramel7	T	A	2: 87,491,373	D106V	possibly damaging	Het
Prdm9	G	T	17: 15,553,346	H263N	probably benign	Het
Psd4	T	A	2: 24,396,787		probably null	Het
Ptprc	G	A	1: 138,099,631	T493I	possibly damaging	Het
Rbbp8	T	A	18: 11,721,979	S420R	probably benign	Het
Sap30bp	A	G	11: 115,962,547	T219A	probably damaging	Het
Slc2a7	T	A	4: 150,157,564	L200Q	probably damaging	Het
Slc38a6	T	A	12: 73,288,525		probably null	Het
Tatdn2	T	A	6: 113,704,024		probably benign	Het
Thrb	A	G	14: 18,011,056		probably benign	Het
Timp4	T	C	6: 115,246,308	Y218C	possibly damaging	Het
Tlr5	A	G	1: 182,974,748	D525G	probably benign	Het
Usp32	G	T	11: 84,988,482	T1467N	probably benign	Het
Zbtb43	T	C	2: 33,454,091	H374R	probably benign	Het
Zfhx4	C	A	3: 5,243,568	T618K	probably damaging	Het

Other mutations in Vmn2r78

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01473:Vmn2r78	APN	7	86920312	missense	possibly damaging	0.61
IGL01767:Vmn2r78	APN	7	86954435	missense	probably benign	0.28
IGL02322:Vmn2r78	APN	7	86921479	missense	probably damaging	0.96
IGL02537:Vmn2r78	APN	7	86954288	missense	probably damaging	0.99
IGL03297:Vmn2r78	APN	7	86920761	nonsense	probably null
ANU74:Vmn2r78	UTSW	7	86921065	missense	possibly damaging	0.62
R0035:Vmn2r78	UTSW	7	86920205	missense	probably benign	0.22
R0081:Vmn2r78	UTSW	7	86923027	missense	probably benign	0.35
R0401:Vmn2r78	UTSW	7	86921311	missense	probably benign	0.04
R0751:Vmn2r78	UTSW	7	86954380	missense	possibly damaging	0.77
R1341:Vmn2r78	UTSW	7	86922269	missense	possibly damaging	0.71
R1386:Vmn2r78	UTSW	7	86915407	missense	unknown
R1526:Vmn2r78	UTSW	7	86922257	splice site	probably null
R1712:Vmn2r78	UTSW	7	86954924	missense	probably damaging	1.00
R1739:Vmn2r78	UTSW	7	86920789	missense	probably benign
R1812:Vmn2r78	UTSW	7	86920787	missense	probably benign	0.38
R2011:Vmn2r78	UTSW	7	86955079	missense	possibly damaging	0.52
R2144:Vmn2r78	UTSW	7	86954482	missense	probably damaging	1.00
R2197:Vmn2r78	UTSW	7	86921327	missense	probably damaging	0.96
R2291:Vmn2r78	UTSW	7	86920154	missense	probably damaging	1.00
R2409:Vmn2r78	UTSW	7	86920745	splice site	probably benign
R3023:Vmn2r78	UTSW	7	86954966	missense	probably damaging	1.00
R4486:Vmn2r78	UTSW	7	86920751	critical splice acceptor site	probably null
R4512:Vmn2r78	UTSW	7	86920244	missense	probably benign	0.00
R4515:Vmn2r78	UTSW	7	86954258	missense	probably damaging	0.99
R4544:Vmn2r78	UTSW	7	86921191	missense	probably benign
R4546:Vmn2r78	UTSW	7	86954603	missense	probably damaging	1.00
R4872:Vmn2r78	UTSW	7	86954708	missense	possibly damaging	0.87
R4928:Vmn2r78	UTSW	7	86954627	missense	probably damaging	1.00
R5101:Vmn2r78	UTSW	7	86922355	missense	probably damaging	1.00
R5265:Vmn2r78	UTSW	7	86920124	missense	probably damaging	1.00
R5328:Vmn2r78	UTSW	7	86921030	missense	probably damaging	0.98
R5442:Vmn2r78	UTSW	7	86920122	missense	possibly damaging	0.95
R5567:Vmn2r78	UTSW	7	86921529	missense	probably benign	0.17
R5572:Vmn2r78	UTSW	7	86915512	missense	probably benign	0.01
R5636:Vmn2r78	UTSW	7	86954429	missense	probably damaging	0.99
R5901:Vmn2r78	UTSW	7	86954588	missense	probably damaging	1.00
R5977:Vmn2r78	UTSW	7	86920333	missense	possibly damaging	0.74
R5977:Vmn2r78	UTSW	7	86954907	missense	probably benign	0.00
R6276:Vmn2r78	UTSW	7	86921110	missense	probably benign	0.00
R6386:Vmn2r78	UTSW	7	86922337	nonsense	probably null
R6724:Vmn2r78	UTSW	7	86954258	missense	probably damaging	0.99
R6852:Vmn2r78	UTSW	7	86954603	missense	probably damaging	1.00
R6896:Vmn2r78	UTSW	7	86922350	missense	probably benign	0.10
R7385:Vmn2r78	UTSW	7	86922425	missense	probably benign	0.18
R7578:Vmn2r78	UTSW	7	86954344	nonsense	probably null
R7680:Vmn2r78	UTSW	7	86954941	missense	probably damaging	1.00
R7748:Vmn2r78	UTSW	7	86921135	missense	probably benign	0.00
R7852:Vmn2r78	UTSW	7	86920170	nonsense	probably null
R8031:Vmn2r78	UTSW	7	86954867	missense	probably damaging	1.00
R8070:Vmn2r78	UTSW	7	86922487	missense	probably benign	0.01
R8085:Vmn2r78	UTSW	7	86954790	missense	probably benign	0.00
R8163:Vmn2r78	UTSW	7	86954452	missense	probably damaging	1.00
RF018:Vmn2r78	UTSW	7	86954431	nonsense	probably null
Z1177:Vmn2r78	UTSW	7	86921207	missense	probably benign	0.44
Z1177:Vmn2r78	UTSW	7	86954774	missense	probably benign	0.02

Posted On

2013-10-07