Mutagenetix > Incidental Mutation

Incidental Mutation 'R9776:Pdzd2'

733736

Institutional Source

Beutler Lab

Gene Symbol

Pdzd2

Ensembl Gene

ENSMUSG00000022197

Gene Name

PDZ domain containing 2

Synonyms

Gm21706, A930022H17Rik, Pdzk3, 4930537L06Rik, LOC223364

MMRRC Submission

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.117) question?

Stock #

R9776 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

12359797-12740010 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 12457909 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Serine at position 144 (F144S)

Ref Sequence

ENSEMBL: ENSMUSP00000140682 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000075317] [ENSMUST00000186113] [ENSMUST00000189324] [ENSMUST00000190929]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000075317
AA Change: F318S

PolyPhen 2 Score 0.699 (Sensitivity: 0.86; Specificity: 0.92)

SMART Domains

Protein: ENSMUSP00000074788
Gene: ENSMUSG00000022197
AA Change: F318S

Domain	Start	End	E-Value	Type
PDZ	81	179	1.27e-2	SMART
PDZ	342	419	1.51e-18	SMART
PDZ	597	675	5.25e-18	SMART
low complexity region	690	718	N/A	INTRINSIC
PDZ	738	817	1.64e-10	SMART
low complexity region	861	869	N/A	INTRINSIC
low complexity region	969	984	N/A	INTRINSIC
low complexity region	986	1000	N/A	INTRINSIC
low complexity region	1436	1459	N/A	INTRINSIC
low complexity region	1525	1537	N/A	INTRINSIC
low complexity region	1538	1553	N/A	INTRINSIC
low complexity region	1567	1586	N/A	INTRINSIC
low complexity region	2111	2129	N/A	INTRINSIC
low complexity region	2190	2198	N/A	INTRINSIC
low complexity region	2335	2354	N/A	INTRINSIC
low complexity region	2469	2479	N/A	INTRINSIC
PDZ	2589	2666	1.3e-13	SMART
PDZ	2716	2794	9.42e-20	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000186113

Predicted Effect

probably benign
Transcript: ENSMUST00000189324

Predicted Effect

probably benign
Transcript: ENSMUST00000190929
AA Change: F144S

PolyPhen 2 Score 0.027 (Sensitivity: 0.95; Specificity: 0.81)

SMART Domains

Protein: ENSMUSP00000140682
Gene: ENSMUSG00000022197
AA Change: F144S

Domain	Start	End	E-Value	Type
PDZ	168	245	3e-20	SMART

Coding Region Coverage

1x: 99.9%
3x: 99.8%
10x: 99.4%
20x: 98.5%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Dec 2015]
PHENOTYPE: Mice homozygous for a gene trapped allele exhibit normal response to acute and chronic pain. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 83 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700069L16Rik	T	G	5: 113,861,765 (GRCm39)	Q35P	unknown	Het
2010109A12Rik	T	A	5: 93,361,305 (GRCm39)	*120K	probably null	Het
2700049A03Rik	A	G	12: 71,235,448 (GRCm39)	T1133A	possibly damaging	Het
A830005F24Rik	G	A	13: 48,667,758 (GRCm39)	R20Q	unknown	Het
Acta2	T	C	19: 34,223,481 (GRCm39)	T205A	probably benign	Het
Adcy5	A	G	16: 35,100,725 (GRCm39)	D759G	probably damaging	Het
Ankk1	T	A	9: 49,330,714 (GRCm39)	M276L	probably benign	Het
Arfgef2	G	A	2: 166,713,447 (GRCm39)	E1283K	probably damaging	Het
Arhgef26	G	T	3: 62,246,803 (GRCm39)		probably benign	Het
Arhgef28	A	C	13: 98,133,415 (GRCm39)	S351A	probably benign	Het
Arih2	C	T	9: 108,484,504 (GRCm39)	G436S	probably damaging	Het
Bptf	T	C	11: 106,969,396 (GRCm39)	T1013A	probably damaging	Het
Camsap1	A	T	2: 25,828,166 (GRCm39)	V1186E	probably benign	Het
Capn10	G	T	1: 92,871,586 (GRCm39)	A395S	possibly damaging	Het
Ccdc184	A	T	15: 98,066,737 (GRCm39)	T181S	probably damaging	Het
Clasp1	T	C	1: 118,509,108 (GRCm39)	I1345T	possibly damaging	Het
Cpsf1	A	T	15: 76,486,779 (GRCm39)	H252Q	probably damaging	Het
Ctnna2	T	A	6: 77,582,172 (GRCm39)	M363L	probably benign	Het
Cyp24a1	G	A	2: 170,338,625 (GRCm39)	P24S	probably benign	Het
D130040H23Rik	A	G	8: 69,755,566 (GRCm39)	H341R	probably damaging	Het
Dclk3	A	G	9: 111,298,226 (GRCm39)	E590G	probably damaging	Het
Ear2	A	T	14: 44,340,729 (GRCm39)	Y129F	probably benign	Het
Egf	A	G	3: 129,530,514 (GRCm39)	L216P	probably damaging	Het
Fbxw9	T	A	8: 85,792,523 (GRCm39)	H319Q	probably damaging	Het
Gipr	A	G	7: 18,891,487 (GRCm39)	S397P	probably damaging	Het
Gxylt2	G	T	6: 100,682,072 (GRCm39)	E90*	probably null	Het
Hnf1b	T	C	11: 83,784,283 (GRCm39)	V473A	probably benign	Het
Iffo1	G	A	6: 125,130,436 (GRCm39)	E475K	probably damaging	Het
Ifi206	T	A	1: 173,308,075 (GRCm39)	R640S		Het
Ipmk	A	G	10: 71,217,439 (GRCm39)	S328G	probably damaging	Het
Kcnq1	A	T	7: 142,737,368 (GRCm39)	I229F	probably damaging	Het
Kif9	C	A	9: 110,350,398 (GRCm39)	T763N	probably benign	Het
Klhl36	C	T	8: 120,601,129 (GRCm39)	Q383*	probably null	Het
Lrp4	G	T	2: 91,316,179 (GRCm39)	V766F	probably damaging	Het
Mettl26	T	A	17: 26,094,511 (GRCm39)	M3K	probably benign	Het
Muc16	T	A	9: 18,570,675 (GRCm39)	I615F	unknown	Het
Myo7b	T	A	18: 32,133,068 (GRCm39)	Q427L	probably benign	Het
Naip1	A	G	13: 100,559,584 (GRCm39)	M1140T	probably benign	Het
Ncapg	G	A	5: 45,829,834 (GRCm39)	V179I	probably damaging	Het
Nme4	C	T	17: 26,314,410 (GRCm39)	G6E	possibly damaging	Het
Nr1h4	T	C	10: 89,319,311 (GRCm39)	Y185C	probably damaging	Het
Nt5c3b	T	C	11: 100,327,012 (GRCm39)	I95V	probably benign	Het
Ntaq1	A	G	15: 58,004,913 (GRCm39)	T9A	probably benign	Het
Or2y3	C	T	17: 38,393,470 (GRCm39)	R133H	probably benign	Het
Or5g9	A	T	2: 85,552,145 (GRCm39)	Y132F	probably damaging	Het
Or5t16	A	T	2: 86,819,055 (GRCm39)	I155N	probably damaging	Het
Pappa2	G	T	1: 158,611,481 (GRCm39)	P1494Q	probably damaging	Het
Phactr3	A	G	2: 177,975,896 (GRCm39)	H547R	probably damaging	Het
Pik3c2b	T	A	1: 133,018,588 (GRCm39)	S1012T	possibly damaging	Het
Plppr2	G	A	9: 21,859,107 (GRCm39)	G408D	probably damaging	Het
Pom121	T	A	5: 135,420,554 (GRCm39)	N289I	unknown	Het
Ppa1	T	A	10: 61,487,362 (GRCm39)	S30T	probably damaging	Het
Rgs5	A	T	1: 169,518,089 (GRCm39)	K108*	probably null	Het
Rpap1	A	G	2: 119,607,278 (GRCm39)	V287A	probably benign	Het
Ryr1	A	G	7: 28,774,664 (GRCm39)	Y2326H	probably damaging	Het
Ryr2	A	G	13: 11,707,599 (GRCm39)	S2813P	probably damaging	Het
Sap25	T	C	5: 137,640,702 (GRCm39)		probably null	Het
Senp5	T	C	16: 31,782,279 (GRCm39)	Y739C	probably damaging	Het
Slc25a29	A	T	12: 108,793,017 (GRCm39)	L187Q	possibly damaging	Het
Slc7a2	C	T	8: 41,358,641 (GRCm39)	T328M	probably damaging	Het
Slc7a8	T	C	14: 55,018,759 (GRCm39)	N9S	probably benign	Het
Snx18	A	G	13: 113,754,039 (GRCm39)	V298A	probably benign	Het
Spo11	T	A	2: 172,833,904 (GRCm39)	I342N	possibly damaging	Het
Ssc5d	A	G	7: 4,932,367 (GRCm39)	K344E	probably benign	Het
Sspo	A	T	6: 48,439,269 (GRCm39)	D1639V	probably benign	Het
Stk32b	T	C	5: 37,617,001 (GRCm39)	D285G	probably benign	Het
Sult1b1	T	C	5: 87,662,815 (GRCm39)	D295G	probably benign	Het
Syt5	A	G	7: 4,544,831 (GRCm39)	L274P	probably damaging	Het
Tas1r2	T	C	4: 139,396,208 (GRCm39)	S545P	possibly damaging	Het
Tbc1d17	T	G	7: 44,490,696 (GRCm39)	D632A	probably damaging	Het
Tbc1d2	A	G	4: 46,650,007 (GRCm39)	S10P	probably benign	Het
Tlk1	A	T	2: 70,555,908 (GRCm39)	I417N	probably damaging	Het
Tmem184a	C	T	5: 139,791,984 (GRCm39)	R348H	possibly damaging	Het
Togaram2	T	A	17: 72,023,508 (GRCm39)	V808D	possibly damaging	Het
Tpr	A	G	1: 150,324,939 (GRCm39)	Q2397R	probably benign	Het
Trav7-4	A	G	14: 53,698,994 (GRCm39)	D47G	possibly damaging	Het
Usp17le	T	A	7: 104,419,814 (GRCm39)	M35L	probably benign	Het
Vegfc	C	T	8: 54,633,829 (GRCm39)	S262L	probably benign	Het
Vmn2r74	T	A	7: 85,605,212 (GRCm39)	I479L	possibly damaging	Het
Vps13a	A	T	19: 16,736,958 (GRCm39)	F126L	probably benign	Het
Zfp945	C	A	17: 23,070,582 (GRCm39)	C460F	possibly damaging	Het
Zmym4	G	T	4: 126,804,942 (GRCm39)	S439R	possibly damaging	Het
Zscan4-ps3	A	G	7: 11,344,093 (GRCm39)	E17G	probably damaging	Het

Other mutations in Pdzd2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00159:Pdzd2	APN	15	12,458,069 (GRCm39)	missense	possibly damaging	0.93
IGL00586:Pdzd2	APN	15	12,365,853 (GRCm39)	splice site	probably null
IGL00697:Pdzd2	APN	15	12,373,733 (GRCm39)	missense	possibly damaging	0.81
IGL00721:Pdzd2	APN	15	12,374,498 (GRCm39)	missense	probably benign	0.00
IGL00971:Pdzd2	APN	15	12,374,804 (GRCm39)	missense	probably benign	0.00
IGL01066:Pdzd2	APN	15	12,402,718 (GRCm39)	unclassified	probably benign
IGL01389:Pdzd2	APN	15	12,374,712 (GRCm39)	missense	possibly damaging	0.56
IGL01505:Pdzd2	APN	15	12,458,293 (GRCm39)	missense	probably damaging	1.00
IGL01527:Pdzd2	APN	15	12,445,750 (GRCm39)	missense	probably damaging	1.00
IGL01584:Pdzd2	APN	15	12,592,569 (GRCm39)	missense	probably damaging	1.00
IGL01763:Pdzd2	APN	15	12,372,632 (GRCm39)	missense	probably benign
IGL01915:Pdzd2	APN	15	12,371,725 (GRCm39)	missense	probably damaging	1.00
IGL01947:Pdzd2	APN	15	12,592,440 (GRCm39)	missense	probably damaging	1.00
IGL02058:Pdzd2	APN	15	12,376,382 (GRCm39)	missense	possibly damaging	0.87
IGL02274:Pdzd2	APN	15	12,445,735 (GRCm39)	missense	probably damaging	1.00
IGL02408:Pdzd2	APN	15	12,375,851 (GRCm39)	missense	probably benign	0.00
IGL02600:Pdzd2	APN	15	12,411,105 (GRCm39)	missense	probably damaging	1.00
IGL02637:Pdzd2	APN	15	12,385,720 (GRCm39)	missense	probably benign	0.13
IGL02639:Pdzd2	APN	15	12,592,329 (GRCm39)	missense	probably damaging	1.00
IGL02712:Pdzd2	APN	15	12,376,113 (GRCm39)	missense	probably benign	0.00
IGL02967:Pdzd2	APN	15	12,374,427 (GRCm39)	missense	probably benign	0.04
IGL02992:Pdzd2	APN	15	12,382,708 (GRCm39)	missense	possibly damaging	0.77
IGL03005:Pdzd2	APN	15	12,385,351 (GRCm39)	missense	probably damaging	1.00
IGL03067:Pdzd2	APN	15	12,388,628 (GRCm39)	critical splice donor site	probably null
IGL03335:Pdzd2	APN	15	12,373,850 (GRCm39)	missense	probably benign	0.00
PIT4280001:Pdzd2	UTSW	15	12,399,374 (GRCm39)	missense	probably damaging	1.00
R0022:Pdzd2	UTSW	15	12,371,691 (GRCm39)	missense	possibly damaging	0.94
R0241:Pdzd2	UTSW	15	12,368,027 (GRCm39)	missense	probably damaging	1.00
R0241:Pdzd2	UTSW	15	12,368,027 (GRCm39)	missense	probably damaging	1.00
R0446:Pdzd2	UTSW	15	12,375,110 (GRCm39)	missense	probably benign	0.43
R0462:Pdzd2	UTSW	15	12,592,246 (GRCm39)	missense	probably damaging	1.00
R0562:Pdzd2	UTSW	15	12,592,364 (GRCm39)	missense	probably damaging	1.00
R0589:Pdzd2	UTSW	15	12,376,385 (GRCm39)	missense	probably benign	0.03
R0639:Pdzd2	UTSW	15	12,458,144 (GRCm39)	missense	possibly damaging	0.77
R0925:Pdzd2	UTSW	15	12,399,356 (GRCm39)	missense	probably damaging	1.00
R1015:Pdzd2	UTSW	15	12,374,594 (GRCm39)	missense	probably damaging	1.00
R1054:Pdzd2	UTSW	15	12,371,725 (GRCm39)	missense	probably damaging	1.00
R1070:Pdzd2	UTSW	15	12,390,052 (GRCm39)	critical splice donor site	probably null
R1099:Pdzd2	UTSW	15	12,373,173 (GRCm39)	missense	probably damaging	1.00
R1122:Pdzd2	UTSW	15	12,457,981 (GRCm39)	missense	probably benign	0.25
R1126:Pdzd2	UTSW	15	12,458,306 (GRCm39)	missense	possibly damaging	0.94
R1381:Pdzd2	UTSW	15	12,385,525 (GRCm39)	missense	probably benign	0.02
R1385:Pdzd2	UTSW	15	12,411,108 (GRCm39)	missense	probably benign	0.38
R1513:Pdzd2	UTSW	15	12,373,915 (GRCm39)	missense	possibly damaging	0.88
R1538:Pdzd2	UTSW	15	12,373,047 (GRCm39)	missense	probably damaging	1.00
R1750:Pdzd2	UTSW	15	12,385,950 (GRCm39)	missense	probably damaging	1.00
R1775:Pdzd2	UTSW	15	12,592,546 (GRCm39)	missense	probably damaging	1.00
R1801:Pdzd2	UTSW	15	12,387,740 (GRCm39)	missense	possibly damaging	0.56
R1832:Pdzd2	UTSW	15	12,390,134 (GRCm39)	missense	probably damaging	1.00
R1856:Pdzd2	UTSW	15	12,373,941 (GRCm39)	missense	possibly damaging	0.87
R1870:Pdzd2	UTSW	15	12,457,972 (GRCm39)	missense	probably damaging	1.00
R1879:Pdzd2	UTSW	15	12,373,986 (GRCm39)	missense	possibly damaging	0.61
R2072:Pdzd2	UTSW	15	12,385,905 (GRCm39)	missense	probably damaging	1.00
R2073:Pdzd2	UTSW	15	12,385,905 (GRCm39)	missense	probably damaging	1.00
R2075:Pdzd2	UTSW	15	12,385,905 (GRCm39)	missense	probably damaging	1.00
R2125:Pdzd2	UTSW	15	12,373,676 (GRCm39)	missense	probably benign	0.37
R2142:Pdzd2	UTSW	15	12,406,645 (GRCm39)	missense	probably damaging	1.00
R2155:Pdzd2	UTSW	15	12,375,879 (GRCm39)	missense	probably benign	0.43
R2282:Pdzd2	UTSW	15	12,373,934 (GRCm39)	missense	possibly damaging	0.95
R2407:Pdzd2	UTSW	15	12,373,247 (GRCm39)	missense	probably damaging	1.00
R3545:Pdzd2	UTSW	15	12,375,557 (GRCm39)	missense	probably benign	0.00
R3878:Pdzd2	UTSW	15	12,376,262 (GRCm39)	missense	probably benign	0.00
R3879:Pdzd2	UTSW	15	12,375,594 (GRCm39)	missense	probably damaging	1.00
R4396:Pdzd2	UTSW	15	12,387,732 (GRCm39)	missense	probably benign	0.36
R4398:Pdzd2	UTSW	15	12,376,061 (GRCm39)	missense	probably benign	0.30
R4491:Pdzd2	UTSW	15	12,385,723 (GRCm39)	missense	possibly damaging	0.75
R4492:Pdzd2	UTSW	15	12,419,567 (GRCm39)	missense	possibly damaging	0.48
R4492:Pdzd2	UTSW	15	12,385,723 (GRCm39)	missense	possibly damaging	0.75
R4656:Pdzd2	UTSW	15	12,385,797 (GRCm39)	missense	probably benign	0.00
R4715:Pdzd2	UTSW	15	12,419,602 (GRCm39)	missense	possibly damaging	0.72
R4803:Pdzd2	UTSW	15	12,374,681 (GRCm39)	missense	probably benign	0.04
R4893:Pdzd2	UTSW	15	12,385,429 (GRCm39)	missense	probably benign	0.00
R4959:Pdzd2	UTSW	15	12,375,734 (GRCm39)	missense	probably damaging	1.00
R4973:Pdzd2	UTSW	15	12,375,734 (GRCm39)	missense	probably damaging	1.00
R5030:Pdzd2	UTSW	15	12,592,494 (GRCm39)	nonsense	probably null
R5174:Pdzd2	UTSW	15	12,372,600 (GRCm39)	missense	probably benign	0.01
R5230:Pdzd2	UTSW	15	12,390,119 (GRCm39)	missense	probably damaging	1.00
R5256:Pdzd2	UTSW	15	12,373,028 (GRCm39)	missense	possibly damaging	0.87
R5268:Pdzd2	UTSW	15	12,592,263 (GRCm39)	missense	probably damaging	1.00
R5488:Pdzd2	UTSW	15	12,382,762 (GRCm39)	missense	probably benign	0.00
R5489:Pdzd2	UTSW	15	12,382,762 (GRCm39)	missense	probably benign	0.00
R5588:Pdzd2	UTSW	15	12,374,367 (GRCm39)	missense	possibly damaging	0.48
R5605:Pdzd2	UTSW	15	12,592,436 (GRCm39)	nonsense	probably null
R5704:Pdzd2	UTSW	15	12,385,761 (GRCm39)	missense	probably benign	0.02
R5858:Pdzd2	UTSW	15	12,442,675 (GRCm39)	missense	probably damaging	0.97
R6048:Pdzd2	UTSW	15	12,592,656 (GRCm39)	splice site	probably null
R6222:Pdzd2	UTSW	15	12,374,652 (GRCm39)	missense	probably damaging	1.00
R6311:Pdzd2	UTSW	15	12,458,274 (GRCm39)	missense	probably damaging	1.00
R6734:Pdzd2	UTSW	15	12,592,551 (GRCm39)	missense	probably damaging	1.00
R6897:Pdzd2	UTSW	15	12,385,951 (GRCm39)	missense	probably damaging	1.00
R6900:Pdzd2	UTSW	15	12,374,123 (GRCm39)	missense	probably benign
R6955:Pdzd2	UTSW	15	12,401,550 (GRCm39)	missense	probably damaging	1.00
R6959:Pdzd2	UTSW	15	12,375,993 (GRCm39)	missense	probably benign	0.17
R6992:Pdzd2	UTSW	15	12,457,945 (GRCm39)	missense	probably damaging	1.00
R7014:Pdzd2	UTSW	15	12,373,061 (GRCm39)	missense	probably benign	0.14
R7014:Pdzd2	UTSW	15	12,372,647 (GRCm39)	missense	probably benign	0.13
R7110:Pdzd2	UTSW	15	12,368,099 (GRCm39)	missense	probably damaging	1.00
R7180:Pdzd2	UTSW	15	12,376,209 (GRCm39)	missense	probably damaging	0.99
R7228:Pdzd2	UTSW	15	12,458,231 (GRCm39)	nonsense	probably null
R7228:Pdzd2	UTSW	15	12,373,059 (GRCm39)	missense	probably benign	0.01
R7317:Pdzd2	UTSW	15	12,592,329 (GRCm39)	missense	probably damaging	1.00
R7322:Pdzd2	UTSW	15	12,437,248 (GRCm39)	missense	probably damaging	1.00
R7349:Pdzd2	UTSW	15	12,399,291 (GRCm39)	missense	probably damaging	1.00
R7600:Pdzd2	UTSW	15	12,372,820 (GRCm39)	missense	probably damaging	1.00
R7663:Pdzd2	UTSW	15	12,373,289 (GRCm39)	missense	probably damaging	1.00
R7712:Pdzd2	UTSW	15	12,407,422 (GRCm39)	missense	probably damaging	1.00
R7716:Pdzd2	UTSW	15	12,373,460 (GRCm39)	missense	possibly damaging	0.63
R7740:Pdzd2	UTSW	15	12,374,102 (GRCm39)	missense	probably benign	0.00
R7748:Pdzd2	UTSW	15	12,385,872 (GRCm39)	missense	possibly damaging	0.60
R8017:Pdzd2	UTSW	15	12,373,122 (GRCm39)	missense	probably damaging	1.00
R8019:Pdzd2	UTSW	15	12,373,122 (GRCm39)	missense	probably damaging	1.00
R8108:Pdzd2	UTSW	15	12,373,592 (GRCm39)	missense	probably benign	0.01
R8109:Pdzd2	UTSW	15	12,373,592 (GRCm39)	missense	probably benign	0.01
R8110:Pdzd2	UTSW	15	12,373,592 (GRCm39)	missense	probably benign	0.01
R8111:Pdzd2	UTSW	15	12,373,592 (GRCm39)	missense	probably benign	0.01
R8145:Pdzd2	UTSW	15	12,407,458 (GRCm39)	missense	probably benign	0.37
R8220:Pdzd2	UTSW	15	12,592,249 (GRCm39)	missense	probably damaging	0.99
R8278:Pdzd2	UTSW	15	12,375,995 (GRCm39)	missense	probably benign
R8768:Pdzd2	UTSW	15	12,437,252 (GRCm39)	missense	probably damaging	1.00
R8879:Pdzd2	UTSW	15	12,402,405 (GRCm39)	missense	probably damaging	1.00
R9019:Pdzd2	UTSW	15	12,375,612 (GRCm39)	missense	probably damaging	1.00
R9030:Pdzd2	UTSW	15	12,374,385 (GRCm39)	missense	probably benign	0.02
R9061:Pdzd2	UTSW	15	12,374,753 (GRCm39)	missense	possibly damaging	0.94
R9302:Pdzd2	UTSW	15	12,374,342 (GRCm39)	missense	possibly damaging	0.61
R9321:Pdzd2	UTSW	15	12,386,023 (GRCm39)	missense	probably benign	0.00
R9421:Pdzd2	UTSW	15	12,375,114 (GRCm39)	missense
R9515:Pdzd2	UTSW	15	12,374,621 (GRCm39)	missense	probably damaging	1.00
R9592:Pdzd2	UTSW	15	12,458,106 (GRCm39)	missense	probably damaging	1.00
R9614:Pdzd2	UTSW	15	12,375,486 (GRCm39)	missense	probably damaging	1.00
R9630:Pdzd2	UTSW	15	12,374,443 (GRCm39)	missense	probably benign	0.37
X0057:Pdzd2	UTSW	15	12,411,113 (GRCm39)	missense	probably damaging	1.00
X0063:Pdzd2	UTSW	15	12,368,805 (GRCm39)	missense	possibly damaging	0.77
X0066:Pdzd2	UTSW	15	12,372,942 (GRCm39)	missense	probably benign	0.00

Predicted Primers

PCR Primer
(F):5'- AGATTCTAGGACAGCGAGCCAG -3'
(R):5'- ATGCCTTTGAGCTAGAAAATGG -3'

Sequencing Primer
(F):5'- TTGCCTTGCAAGCATCGAG -3'
(R):5'- ATGGTCCGAATTCTCTCAAGG -3'

Posted On

2022-11-14