Incidental Mutation 'R9655:Iqgap3'
| ID |
735435 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Iqgap3
|
| Ensembl Gene |
ENSMUSG00000028068 |
| Gene Name |
IQ motif containing GTPase activating protein 3 |
| Synonyms |
|
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.314)
|
| Stock # |
R9655 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
87989309-88028355 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 88016728 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Aspartic acid
at position 1070
(V1070D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071715
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071812]
[ENSMUST00000194440]
[ENSMUST00000195465]
|
| AlphaFold |
F8VQ29 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000071812
AA Change: V1070D
PolyPhen 2
Score 0.529 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000071715
Gene: ENSMUSG00000028068
AA Change: V1070D
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
36 |
145 |
1.72e-14 |
SMART |
|
internal_repeat_2
|
197 |
249 |
1.75e-5 |
PROSPERO |
|
internal_repeat_1
|
209 |
418 |
1.31e-14 |
PROSPERO |
|
low complexity region
|
419 |
438 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
446 |
651 |
1.31e-14 |
PROSPERO |
|
internal_repeat_2
|
600 |
652 |
1.75e-5 |
PROSPERO |
|
IQ
|
730 |
752 |
1.18e1 |
SMART |
|
IQ
|
760 |
782 |
3.76e-6 |
SMART |
|
IQ
|
790 |
812 |
3.08e-2 |
SMART |
|
IQ
|
820 |
842 |
1.72e0 |
SMART |
|
RasGAP
|
977 |
1330 |
1.74e-57 |
SMART |
|
Blast:RasGAP
|
1338 |
1422 |
1e-9 |
BLAST |
|
Pfam:RasGAP_C
|
1434 |
1555 |
2e-36 |
PFAM |
|
low complexity region
|
1591 |
1602 |
N/A |
INTRINSIC |
|
low complexity region
|
1615 |
1630 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194440
AA Change: V172D
PolyPhen 2
Score 0.380 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000142035
Gene: ENSMUSG00000028068
AA Change: V172D
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:RasGAP
|
1 |
67 |
3e-30 |
BLAST |
|
RasGAP
|
79 |
432 |
1e-59 |
SMART |
|
Blast:RasGAP
|
440 |
524 |
5e-10 |
BLAST |
|
Pfam:RasGAP_C
|
535 |
660 |
5.7e-30 |
PFAM |
|
low complexity region
|
693 |
704 |
N/A |
INTRINSIC |
|
low complexity region
|
717 |
732 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195465
|
| SMART Domains |
Protein: ENSMUSP00000142013
Gene: ENSMUSG00000028068
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
36 |
145 |
8.5e-17 |
SMART |
|
internal_repeat_1
|
209 |
379 |
1.33e-7 |
PROSPERO |
|
low complexity region
|
419 |
438 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
446 |
612 |
1.33e-7 |
PROSPERO |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.8%
- 10x: 99.4%
- 20x: 98.7%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933402N03Rik |
T |
A |
7: 130,740,695 (GRCm39) |
I174F |
possibly damaging |
Het |
| Ada |
C |
A |
2: 163,574,270 (GRCm39) |
V129F |
probably damaging |
Het |
| Adgrl4 |
G |
T |
3: 151,248,450 (GRCm39) |
M707I |
probably damaging |
Het |
| Ahcyl |
A |
T |
16: 45,974,564 (GRCm39) |
I271N |
probably damaging |
Het |
| Arrb2 |
A |
G |
11: 70,331,073 (GRCm39) |
Q419R |
probably null |
Het |
| Atad2 |
A |
T |
15: 57,998,303 (GRCm39) |
L23Q |
probably damaging |
Het |
| Btbd2 |
A |
T |
10: 80,492,045 (GRCm39) |
F107Y |
probably benign |
Het |
| C7 |
T |
A |
15: 5,041,464 (GRCm39) |
T481S |
probably damaging |
Het |
| Capn10 |
T |
A |
1: 92,867,111 (GRCm39) |
W114R |
probably damaging |
Het |
| Ccdc121 |
C |
T |
5: 31,644,976 (GRCm39) |
T243I |
probably benign |
Het |
| Cdc16 |
T |
A |
8: 13,809,153 (GRCm39) |
D39E |
possibly damaging |
Het |
| Cfap74 |
A |
T |
4: 155,522,665 (GRCm39) |
I684F |
|
Het |
| Cyp2c70 |
T |
A |
19: 40,149,121 (GRCm39) |
N342Y |
possibly damaging |
Het |
| Dnah17 |
G |
A |
11: 117,971,649 (GRCm39) |
T2128I |
possibly damaging |
Het |
| Dnah5 |
A |
G |
15: 28,242,900 (GRCm39) |
N545S |
probably benign |
Het |
| Dnmt3c |
A |
G |
2: 153,561,914 (GRCm39) |
N539S |
probably damaging |
Het |
| Elfn1 |
A |
G |
5: 139,958,964 (GRCm39) |
E656G |
possibly damaging |
Het |
| Exd1 |
A |
T |
2: 119,350,855 (GRCm39) |
C469S |
probably damaging |
Het |
| F5 |
A |
T |
1: 164,021,730 (GRCm39) |
I1402F |
probably benign |
Het |
| Fam186a |
A |
G |
15: 99,840,973 (GRCm39) |
L1757P |
probably damaging |
Het |
| Fbxo42 |
A |
T |
4: 140,895,171 (GRCm39) |
R45W |
probably damaging |
Het |
| Fer1l5 |
T |
C |
1: 36,460,696 (GRCm39) |
V1978A |
probably benign |
Het |
| Fpr1 |
T |
A |
17: 18,097,618 (GRCm39) |
I124F |
probably damaging |
Het |
| Fry |
A |
T |
5: 150,362,251 (GRCm39) |
D2173V |
possibly damaging |
Het |
| Gabbr2 |
G |
T |
4: 46,815,684 (GRCm39) |
T228K |
possibly damaging |
Het |
| Galnt9 |
A |
T |
5: 110,762,104 (GRCm39) |
Y414F |
probably damaging |
Het |
| Gask1a |
T |
A |
9: 121,794,170 (GRCm39) |
L108Q |
probably benign |
Het |
| Ggt5 |
A |
T |
10: 75,444,635 (GRCm39) |
M318L |
probably benign |
Het |
| Glod4 |
A |
C |
11: 76,125,292 (GRCm39) |
S156A |
probably benign |
Het |
| Gm5431 |
A |
T |
11: 48,785,799 (GRCm39) |
M192K |
probably benign |
Het |
| Golga5 |
C |
T |
12: 102,446,008 (GRCm39) |
S421L |
possibly damaging |
Het |
| Gpr18 |
T |
C |
14: 122,149,992 (GRCm39) |
D11G |
probably benign |
Het |
| Igf2bp3 |
C |
T |
6: 49,064,338 (GRCm39) |
V560I |
probably benign |
Het |
| Igfals |
A |
G |
17: 25,099,665 (GRCm39) |
N252S |
probably damaging |
Het |
| Ighv8-5 |
C |
T |
12: 115,031,416 (GRCm39) |
C41Y |
probably damaging |
Het |
| Kdr |
G |
A |
5: 76,122,488 (GRCm39) |
A479V |
probably benign |
Het |
| Kidins220 |
T |
C |
12: 25,047,295 (GRCm39) |
L247P |
probably damaging |
Het |
| Kmt5a |
A |
G |
5: 124,589,393 (GRCm39) |
Y197C |
probably damaging |
Het |
| Krt33a |
A |
C |
11: 99,906,624 (GRCm39) |
|
probably null |
Het |
| Mageb3 |
A |
G |
2: 121,785,649 (GRCm39) |
S18P |
unknown |
Het |
| Mast1 |
T |
A |
8: 85,650,660 (GRCm39) |
Y387F |
probably damaging |
Het |
| Mcm5 |
C |
T |
8: 75,844,168 (GRCm39) |
S313F |
probably benign |
Het |
| Med17 |
C |
T |
9: 15,176,719 (GRCm39) |
V503M |
possibly damaging |
Het |
| Mpp3 |
A |
G |
11: 101,899,481 (GRCm39) |
C347R |
probably benign |
Het |
| Mtr |
A |
G |
13: 12,203,030 (GRCm39) |
L1191P |
probably damaging |
Het |
| Mybphl |
A |
T |
3: 108,282,099 (GRCm39) |
I110F |
probably damaging |
Het |
| Nkx2-1 |
T |
A |
12: 56,581,802 (GRCm39) |
D15V |
probably damaging |
Het |
| Nwd2 |
G |
A |
5: 63,964,568 (GRCm39) |
W1384* |
probably null |
Het |
| Onecut1 |
A |
G |
9: 74,770,330 (GRCm39) |
H251R |
possibly damaging |
Het |
| Or10ak8 |
T |
A |
4: 118,773,804 (GRCm39) |
N287Y |
probably damaging |
Het |
| Or13f5 |
C |
T |
4: 52,825,526 (GRCm39) |
T43I |
probably benign |
Het |
| Or51a6 |
A |
G |
7: 102,604,319 (GRCm39) |
F163S |
probably damaging |
Het |
| Or8b37 |
A |
T |
9: 37,959,387 (GRCm39) |
I290L |
probably benign |
Het |
| Palmd |
T |
C |
3: 116,716,840 (GRCm39) |
*552W |
probably null |
Het |
| Pcdhgb2 |
A |
G |
18: 37,823,285 (GRCm39) |
E92G |
probably damaging |
Het |
| Pcdhgb5 |
G |
T |
18: 37,865,122 (GRCm39) |
E306* |
probably null |
Het |
| Peg10 |
CCACATCAGGATCCACATCAGGATGCACATCAGCATCAGGATCCCCATCAGGATGCACATCAGGATCCACATCAGGATGCACATCAG |
CCACATCAGGATCCACATCAGGATGCACATCAG |
6: 4,756,398 (GRCm39) |
|
probably benign |
Het |
| Pex1 |
T |
A |
5: 3,655,653 (GRCm39) |
L160Q |
probably damaging |
Het |
| Phxr2 |
A |
T |
10: 98,961,974 (GRCm39) |
S29T |
unknown |
Het |
| Ppargc1a |
A |
G |
5: 51,705,852 (GRCm39) |
|
probably null |
Het |
| Psmb11 |
T |
C |
14: 54,862,965 (GRCm39) |
V61A |
probably damaging |
Het |
| Ripor2 |
A |
T |
13: 24,908,983 (GRCm39) |
I1034F |
possibly damaging |
Het |
| Rnaset2b |
T |
A |
17: 7,259,134 (GRCm39) |
N133K |
probably damaging |
Het |
| Rtn4 |
A |
G |
11: 29,657,504 (GRCm39) |
T553A |
probably damaging |
Het |
| Samd9l |
T |
A |
6: 3,373,578 (GRCm39) |
T1228S |
probably benign |
Het |
| Sdr42e2 |
A |
G |
7: 120,430,279 (GRCm39) |
T379A |
probably benign |
Het |
| Shisal2a |
C |
A |
4: 108,234,616 (GRCm39) |
V84L |
possibly damaging |
Het |
| Slc1a1 |
C |
T |
19: 28,870,283 (GRCm39) |
A94V |
probably damaging |
Het |
| Snx31 |
C |
T |
15: 36,534,582 (GRCm39) |
C197Y |
probably damaging |
Het |
| Tbc1d4 |
A |
G |
14: 101,744,567 (GRCm39) |
V353A |
probably damaging |
Het |
| Tbc1d9b |
A |
G |
11: 50,059,610 (GRCm39) |
D1004G |
possibly damaging |
Het |
| Tex15 |
T |
A |
8: 34,066,784 (GRCm39) |
Y2071* |
probably null |
Het |
| Tnni3k |
G |
A |
3: 154,645,410 (GRCm39) |
R492* |
probably null |
Het |
| Tns2 |
A |
G |
15: 102,012,933 (GRCm39) |
H7R |
probably benign |
Het |
| Top2a |
G |
T |
11: 98,905,334 (GRCm39) |
N369K |
probably damaging |
Het |
| Tpbg |
A |
T |
9: 85,726,252 (GRCm39) |
T74S |
probably damaging |
Het |
| Trpm6 |
A |
G |
19: 18,869,466 (GRCm39) |
N2018D |
probably benign |
Het |
| Trub2 |
A |
T |
2: 29,669,833 (GRCm39) |
|
probably null |
Het |
| Vps13d |
A |
G |
4: 144,813,305 (GRCm39) |
F3324L |
|
Het |
| Wdr20rt |
A |
T |
12: 65,273,707 (GRCm39) |
Q390L |
probably benign |
Het |
| Wdr49 |
T |
A |
3: 75,240,561 (GRCm39) |
D436V |
probably damaging |
Het |
| Zfp111 |
C |
T |
7: 23,898,543 (GRCm39) |
G357D |
probably damaging |
Het |
| Zfp668 |
A |
G |
7: 127,466,113 (GRCm39) |
V357A |
possibly damaging |
Het |
|
| Other mutations in Iqgap3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01016:Iqgap3
|
APN |
3 |
88,014,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01062:Iqgap3
|
APN |
3 |
88,017,429 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01517:Iqgap3
|
APN |
3 |
88,016,703 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01530:Iqgap3
|
APN |
3 |
88,019,610 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01658:Iqgap3
|
APN |
3 |
88,023,278 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02027:Iqgap3
|
APN |
3 |
87,994,649 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02352:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02359:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02522:Iqgap3
|
APN |
3 |
88,015,705 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02717:Iqgap3
|
APN |
3 |
88,005,666 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02971:Iqgap3
|
APN |
3 |
87,997,611 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL03079:Iqgap3
|
APN |
3 |
88,020,477 (GRCm39) |
missense |
probably benign |
|
|
IGL03240:Iqgap3
|
APN |
3 |
88,022,281 (GRCm39) |
missense |
probably benign |
0.00 |
|
adjutant
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Booster
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
peso_ligero
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0285:Iqgap3
|
UTSW |
3 |
88,004,297 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0442:Iqgap3
|
UTSW |
3 |
88,023,266 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0490:Iqgap3
|
UTSW |
3 |
88,021,363 (GRCm39) |
splice site |
probably benign |
|
|
R0569:Iqgap3
|
UTSW |
3 |
87,998,032 (GRCm39) |
splice site |
probably benign |
|
|
R0747:Iqgap3
|
UTSW |
3 |
88,014,810 (GRCm39) |
splice site |
probably benign |
|
|
R0843:Iqgap3
|
UTSW |
3 |
88,015,738 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1260:Iqgap3
|
UTSW |
3 |
88,021,330 (GRCm39) |
missense |
probably benign |
|
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1544:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1662:Iqgap3
|
UTSW |
3 |
88,005,708 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1686:Iqgap3
|
UTSW |
3 |
88,015,663 (GRCm39) |
splice site |
probably benign |
|
|
R1748:Iqgap3
|
UTSW |
3 |
88,021,287 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1836:Iqgap3
|
UTSW |
3 |
88,015,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1972:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R1973:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R2051:Iqgap3
|
UTSW |
3 |
88,027,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2314:Iqgap3
|
UTSW |
3 |
88,023,338 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2352:Iqgap3
|
UTSW |
3 |
88,011,815 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2857:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R2859:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R3435:Iqgap3
|
UTSW |
3 |
88,001,911 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3522:Iqgap3
|
UTSW |
3 |
87,998,089 (GRCm39) |
missense |
probably null |
0.90 |
|
R4281:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4283:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4397:Iqgap3
|
UTSW |
3 |
88,011,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4414:Iqgap3
|
UTSW |
3 |
88,004,293 (GRCm39) |
missense |
probably benign |
|
|
R4660:Iqgap3
|
UTSW |
3 |
88,027,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4872:Iqgap3
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4883:Iqgap3
|
UTSW |
3 |
88,014,842 (GRCm39) |
missense |
probably benign |
|
|
R4915:Iqgap3
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5050:Iqgap3
|
UTSW |
3 |
87,997,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5130:Iqgap3
|
UTSW |
3 |
88,016,161 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5151:Iqgap3
|
UTSW |
3 |
88,025,067 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R5645:Iqgap3
|
UTSW |
3 |
88,025,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5706:Iqgap3
|
UTSW |
3 |
88,023,215 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5748:Iqgap3
|
UTSW |
3 |
88,016,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5880:Iqgap3
|
UTSW |
3 |
88,024,509 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5982:Iqgap3
|
UTSW |
3 |
87,998,899 (GRCm39) |
nonsense |
probably null |
|
|
R6006:Iqgap3
|
UTSW |
3 |
87,998,854 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6026:Iqgap3
|
UTSW |
3 |
87,997,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6188:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6211:Iqgap3
|
UTSW |
3 |
87,998,822 (GRCm39) |
missense |
probably benign |
|
|
R6291:Iqgap3
|
UTSW |
3 |
87,997,037 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6344:Iqgap3
|
UTSW |
3 |
87,989,401 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6854:Iqgap3
|
UTSW |
3 |
88,004,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6877:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6958:Iqgap3
|
UTSW |
3 |
88,020,673 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7008:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R7050:Iqgap3
|
UTSW |
3 |
88,006,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7144:Iqgap3
|
UTSW |
3 |
88,024,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7170:Iqgap3
|
UTSW |
3 |
88,009,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7288:Iqgap3
|
UTSW |
3 |
88,016,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7952:Iqgap3
|
UTSW |
3 |
88,005,677 (GRCm39) |
missense |
probably benign |
|
|
R8008:Iqgap3
|
UTSW |
3 |
88,016,770 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8049:Iqgap3
|
UTSW |
3 |
88,011,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8176:Iqgap3
|
UTSW |
3 |
88,001,957 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8190:Iqgap3
|
UTSW |
3 |
87,998,086 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8772:Iqgap3
|
UTSW |
3 |
87,997,144 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8878:Iqgap3
|
UTSW |
3 |
88,020,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8893:Iqgap3
|
UTSW |
3 |
87,997,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9072:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9072:Iqgap3
|
UTSW |
3 |
87,998,883 (GRCm39) |
missense |
probably benign |
|
|
R9073:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9337:Iqgap3
|
UTSW |
3 |
88,023,425 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9489:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9492:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9593:Iqgap3
|
UTSW |
3 |
88,011,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9708:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9709:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9752:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9753:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9765:Iqgap3
|
UTSW |
3 |
88,017,361 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R9771:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9772:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Iqgap3
|
UTSW |
3 |
87,996,278 (GRCm39) |
critical splice donor site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TAGCTATGTCCTCCTTAAAGGCATG -3'
(R):5'- AGCAGAGAAAGTCATGGCCC -3'
Sequencing Primer
(F):5'- ATGAGGCCAGTGACCTATTGCAC -3'
(R):5'- ATGGCCCAAGTCTCCTATAGG -3'
|
| Posted On |
2022-11-14 |
Incidental Mutation