Incidental Mutation 'R9658:Tns1'
| ID |
735513 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tns1
|
| Ensembl Gene |
ENSMUSG00000055322 |
| Gene Name |
tensin 1 |
| Synonyms |
E030018G17Rik, 1110018I21Rik, E030037J05Rik, 1200014E20Rik, Tns |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.565)
|
| Stock # |
R9658 (G1)
|
| Quality Score |
215.009 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
73949390-74163608 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to C
at 73981182 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Glutamic Acid
at position 1061
(Q1061E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000127715
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000169786]
[ENSMUST00000187584]
[ENSMUST00000191104]
[ENSMUST00000212888]
|
| AlphaFold |
E9Q0S6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000169786
AA Change: Q1061E
PolyPhen 2
Score 0.145 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000127715
Gene: ENSMUSG00000055322
AA Change: Q1061E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
33 |
N/A |
INTRINSIC |
|
C1
|
62 |
108 |
1.77e-2 |
SMART |
|
low complexity region
|
154 |
167 |
N/A |
INTRINSIC |
|
SCOP:d1d5ra2
|
176 |
348 |
3e-32 |
SMART |
|
PTEN_C2
|
350 |
477 |
1.12e-51 |
SMART |
|
low complexity region
|
822 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
905 |
922 |
N/A |
INTRINSIC |
|
low complexity region
|
1227 |
1239 |
N/A |
INTRINSIC |
|
low complexity region
|
1284 |
1300 |
N/A |
INTRINSIC |
|
low complexity region
|
1459 |
1470 |
N/A |
INTRINSIC |
|
low complexity region
|
1518 |
1530 |
N/A |
INTRINSIC |
|
SH2
|
1614 |
1716 |
6.85e-17 |
SMART |
|
PTB
|
1747 |
1888 |
1.69e-29 |
SMART |
|
| Predicted Effect |
|
| Predicted Effect |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000187584
AA Change: Q1017E
PolyPhen 2
Score 0.173 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000140254
Gene: ENSMUSG00000055322
AA Change: Q1017E
| Domain | Start | End | E-Value | Type |
|---|
|
C1
|
21 |
67 |
8.6e-5 |
SMART |
|
low complexity region
|
113 |
124 |
N/A |
INTRINSIC |
|
PTPc_DSPc
|
197 |
319 |
9.9e-6 |
SMART |
|
PTEN_C2
|
306 |
433 |
5.6e-56 |
SMART |
|
low complexity region
|
778 |
789 |
N/A |
INTRINSIC |
|
low complexity region
|
861 |
878 |
N/A |
INTRINSIC |
|
low complexity region
|
1162 |
1174 |
N/A |
INTRINSIC |
|
low complexity region
|
1219 |
1235 |
N/A |
INTRINSIC |
|
low complexity region
|
1394 |
1405 |
N/A |
INTRINSIC |
|
low complexity region
|
1453 |
1465 |
N/A |
INTRINSIC |
|
SH2
|
1549 |
1651 |
4.3e-19 |
SMART |
|
PTB
|
1682 |
1823 |
9e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000189228
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000191104
AA Change: Q1061E
PolyPhen 2
Score 0.173 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000140317
Gene: ENSMUSG00000055322
AA Change: Q1061E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
33 |
N/A |
INTRINSIC |
|
C1
|
62 |
108 |
8.6e-5 |
SMART |
|
low complexity region
|
154 |
167 |
N/A |
INTRINSIC |
|
PTPc_DSPc
|
241 |
363 |
9.9e-6 |
SMART |
|
PTEN_C2
|
350 |
477 |
5.6e-56 |
SMART |
|
low complexity region
|
822 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
905 |
922 |
N/A |
INTRINSIC |
|
low complexity region
|
1206 |
1218 |
N/A |
INTRINSIC |
|
low complexity region
|
1263 |
1279 |
N/A |
INTRINSIC |
|
low complexity region
|
1438 |
1449 |
N/A |
INTRINSIC |
|
low complexity region
|
1497 |
1509 |
N/A |
INTRINSIC |
|
SH2
|
1593 |
1695 |
4.3e-19 |
SMART |
|
PTB
|
1726 |
1867 |
9e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000212888
AA Change: Q1061E
PolyPhen 2
Score 0.136 (Sensitivity: 0.92; Specificity: 0.86)
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 99.4%
- 20x: 98.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced female fertility, and develop kidney cysts and progressive kidney degeneration that may lead to death from renal failure. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 72 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930503L19Rik |
C |
T |
18: 70,600,401 (GRCm39) |
|
probably null |
Het |
| Abca12 |
T |
C |
1: 71,325,634 (GRCm39) |
I1521M |
probably damaging |
Het |
| Abcc3 |
A |
G |
11: 94,263,703 (GRCm39) |
S268P |
possibly damaging |
Het |
| Adamts20 |
G |
C |
15: 94,249,626 (GRCm39) |
P464A |
probably damaging |
Het |
| Apoa1 |
C |
A |
9: 46,141,280 (GRCm39) |
D125E |
probably benign |
Het |
| Atp6v0a1 |
C |
A |
11: 100,909,414 (GRCm39) |
Q48K |
probably benign |
Het |
| Bptf |
T |
C |
11: 107,002,170 (GRCm39) |
N314S |
probably damaging |
Het |
| Cdh20 |
T |
C |
1: 109,988,785 (GRCm39) |
V229A |
probably damaging |
Het |
| Cfap46 |
G |
A |
7: 139,246,229 (GRCm39) |
T378M |
|
Het |
| Clca3b |
T |
A |
3: 144,543,575 (GRCm39) |
D418V |
probably damaging |
Het |
| Dennd4c |
T |
A |
4: 86,754,625 (GRCm39) |
L1545* |
probably null |
Het |
| Dnajc13 |
A |
G |
9: 104,115,728 (GRCm39) |
V27A |
probably benign |
Het |
| Efcab3 |
A |
G |
11: 104,611,120 (GRCm39) |
K321E |
probably benign |
Het |
| Eif2ak2 |
A |
T |
17: 79,183,632 (GRCm39) |
D72E |
probably benign |
Het |
| Eif2ak4 |
T |
C |
2: 118,269,511 (GRCm39) |
I862T |
probably damaging |
Het |
| Eif4g1 |
T |
C |
16: 20,502,863 (GRCm39) |
I1022T |
probably benign |
Het |
| Enpp3 |
A |
T |
10: 24,649,802 (GRCm39) |
*875R |
probably null |
Het |
| F11 |
T |
C |
8: 45,698,671 (GRCm39) |
Y491C |
probably damaging |
Het |
| Fam98c |
A |
C |
7: 28,852,206 (GRCm39) |
W118G |
probably damaging |
Het |
| Fbxo43 |
A |
T |
15: 36,152,282 (GRCm39) |
L509Q |
probably damaging |
Het |
| Fbxw5 |
A |
G |
2: 25,393,870 (GRCm39) |
H366R |
probably damaging |
Het |
| Flt1 |
G |
T |
5: 147,525,377 (GRCm39) |
N920K |
probably damaging |
Het |
| Git1 |
T |
A |
11: 77,390,581 (GRCm39) |
F106I |
probably damaging |
Het |
| Glipr1l2 |
A |
G |
10: 111,942,868 (GRCm39) |
E241G |
probably damaging |
Het |
| Gm2381 |
A |
C |
7: 42,469,729 (GRCm39) |
C132G |
probably damaging |
Het |
| Gm49383 |
A |
G |
12: 69,239,628 (GRCm39) |
I237T |
|
Het |
| Gm7324 |
T |
A |
14: 43,952,282 (GRCm39) |
D308E |
probably benign |
Het |
| Gpr17 |
A |
G |
18: 32,080,421 (GRCm39) |
L214P |
probably damaging |
Het |
| Gtf3c1 |
A |
T |
7: 125,306,734 (GRCm39) |
L39Q |
probably damaging |
Het |
| H2-Q6 |
C |
T |
17: 35,644,185 (GRCm39) |
R56C |
probably damaging |
Het |
| Hcar2 |
T |
C |
5: 124,002,532 (GRCm39) |
T324A |
possibly damaging |
Het |
| Ksr2 |
T |
C |
5: 117,885,425 (GRCm39) |
S750P |
probably damaging |
Het |
| Lipi |
C |
A |
16: 75,357,689 (GRCm39) |
R292L |
probably benign |
Het |
| Map4k3 |
C |
A |
17: 80,961,306 (GRCm39) |
M133I |
probably benign |
Het |
| Marf1 |
A |
T |
16: 13,958,087 (GRCm39) |
L805Q |
probably damaging |
Het |
| Mccc2 |
T |
A |
13: 100,090,754 (GRCm39) |
R460W |
probably damaging |
Het |
| Mgam |
A |
G |
6: 40,721,311 (GRCm39) |
D312G |
possibly damaging |
Het |
| Nadk2 |
A |
T |
15: 9,103,449 (GRCm39) |
K360* |
probably null |
Het |
| Nalf1 |
T |
C |
8: 9,820,114 (GRCm39) |
D302G |
probably benign |
Het |
| Nars2 |
A |
G |
7: 96,689,178 (GRCm39) |
I367V |
probably benign |
Het |
| Nppb |
T |
C |
4: 148,070,951 (GRCm39) |
S109P |
possibly damaging |
Het |
| Odf2 |
G |
A |
2: 29,779,813 (GRCm39) |
R15Q |
probably benign |
Het |
| Or4f59 |
C |
A |
2: 111,872,823 (GRCm39) |
A185S |
probably damaging |
Het |
| Or51l4 |
C |
T |
7: 103,404,028 (GRCm39) |
V255M |
probably damaging |
Het |
| Or5ac25 |
A |
T |
16: 59,182,106 (GRCm39) |
H158Q |
probably damaging |
Het |
| Osbpl1a |
A |
T |
18: 12,889,269 (GRCm39) |
I949N |
probably benign |
Het |
| Pan3 |
T |
C |
5: 147,479,881 (GRCm39) |
F55L |
probably benign |
Het |
| Patj |
A |
G |
4: 98,353,377 (GRCm39) |
D640G |
probably null |
Het |
| Pdxk |
T |
C |
10: 78,287,403 (GRCm39) |
K53E |
probably benign |
Het |
| Pja2 |
A |
G |
17: 64,599,868 (GRCm39) |
S539P |
probably damaging |
Het |
| Plscr1 |
T |
A |
9: 92,148,535 (GRCm39) |
C158* |
probably null |
Het |
| Prdm14 |
T |
C |
1: 13,189,145 (GRCm39) |
T400A |
probably benign |
Het |
| Rag1 |
C |
T |
2: 101,473,229 (GRCm39) |
V638M |
possibly damaging |
Het |
| Ros1 |
A |
G |
10: 51,967,069 (GRCm39) |
S1734P |
probably damaging |
Het |
| S100a9 |
T |
C |
3: 90,600,081 (GRCm39) |
H105R |
unknown |
Het |
| Shisa9 |
A |
T |
16: 12,062,520 (GRCm39) |
Q247L |
possibly damaging |
Het |
| Slc14a1 |
C |
A |
18: 78,152,807 (GRCm39) |
A367S |
probably damaging |
Het |
| Slc27a4 |
G |
A |
2: 29,701,301 (GRCm39) |
R364Q |
probably damaging |
Het |
| Spag17 |
C |
T |
3: 99,934,932 (GRCm39) |
P713S |
possibly damaging |
Het |
| Tbc1d4 |
T |
A |
14: 101,845,856 (GRCm39) |
H14L |
probably damaging |
Het |
| Tmem144 |
T |
A |
3: 79,729,991 (GRCm39) |
Y253F |
probably damaging |
Het |
| Tmem204 |
C |
T |
17: 25,299,322 (GRCm39) |
G66R |
possibly damaging |
Het |
| Tnfrsf1b |
A |
T |
4: 144,942,424 (GRCm39) |
V453E |
probably damaging |
Het |
| Trav5-1 |
A |
G |
14: 52,860,428 (GRCm39) |
K78E |
probably benign |
Het |
| Ttn |
C |
T |
2: 76,715,357 (GRCm39) |
E7912K |
unknown |
Het |
| Usp17lc |
G |
A |
7: 103,067,389 (GRCm39) |
G228D |
possibly damaging |
Het |
| Uvssa |
T |
C |
5: 33,568,333 (GRCm39) |
C574R |
probably damaging |
Het |
| Veph1 |
G |
A |
3: 66,171,434 (GRCm39) |
Q3* |
probably null |
Het |
| Vps13b |
T |
A |
15: 35,623,774 (GRCm39) |
D1230E |
probably benign |
Het |
| Xkr9 |
T |
A |
1: 13,771,318 (GRCm39) |
I278N |
probably damaging |
Het |
| Zbed4 |
C |
A |
15: 88,664,742 (GRCm39) |
A270E |
probably benign |
Het |
| Zfp366 |
A |
T |
13: 99,365,435 (GRCm39) |
T199S |
probably benign |
Het |
|
| Other mutations in Tns1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00954:Tns1
|
APN |
1 |
73,964,128 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01288:Tns1
|
APN |
1 |
73,992,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01536:Tns1
|
APN |
1 |
73,958,807 (GRCm39) |
splice site |
probably benign |
|
|
IGL01568:Tns1
|
APN |
1 |
73,992,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01683:Tns1
|
APN |
1 |
73,992,428 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02267:Tns1
|
APN |
1 |
74,031,290 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02597:Tns1
|
APN |
1 |
74,025,032 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02819:Tns1
|
APN |
1 |
73,976,407 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03370:Tns1
|
APN |
1 |
74,025,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0087:Tns1
|
UTSW |
1 |
73,956,076 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0207:Tns1
|
UTSW |
1 |
73,976,477 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0411:Tns1
|
UTSW |
1 |
73,964,920 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0543:Tns1
|
UTSW |
1 |
73,991,856 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0552:Tns1
|
UTSW |
1 |
73,959,722 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0720:Tns1
|
UTSW |
1 |
73,964,740 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0828:Tns1
|
UTSW |
1 |
73,958,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1034:Tns1
|
UTSW |
1 |
73,981,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1061:Tns1
|
UTSW |
1 |
73,956,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1819:Tns1
|
UTSW |
1 |
73,955,635 (GRCm39) |
splice site |
probably benign |
|
|
R1826:Tns1
|
UTSW |
1 |
73,992,793 (GRCm39) |
start codon destroyed |
probably null |
0.91 |
|
R2208:Tns1
|
UTSW |
1 |
74,118,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3723:Tns1
|
UTSW |
1 |
73,964,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4079:Tns1
|
UTSW |
1 |
74,034,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4111:Tns1
|
UTSW |
1 |
73,981,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4155:Tns1
|
UTSW |
1 |
73,953,790 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4156:Tns1
|
UTSW |
1 |
73,953,790 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4157:Tns1
|
UTSW |
1 |
73,953,790 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4274:Tns1
|
UTSW |
1 |
73,967,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4426:Tns1
|
UTSW |
1 |
74,024,908 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4649:Tns1
|
UTSW |
1 |
73,992,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4742:Tns1
|
UTSW |
1 |
74,163,449 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4869:Tns1
|
UTSW |
1 |
73,991,774 (GRCm39) |
missense |
probably benign |
|
|
R4961:Tns1
|
UTSW |
1 |
73,975,074 (GRCm39) |
missense |
probably benign |
0.35 |
|
R5025:Tns1
|
UTSW |
1 |
73,964,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5035:Tns1
|
UTSW |
1 |
73,992,979 (GRCm39) |
start gained |
probably benign |
|
|
R5062:Tns1
|
UTSW |
1 |
73,992,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5080:Tns1
|
UTSW |
1 |
73,992,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5213:Tns1
|
UTSW |
1 |
73,992,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5256:Tns1
|
UTSW |
1 |
74,034,585 (GRCm39) |
intron |
probably benign |
|
|
R5368:Tns1
|
UTSW |
1 |
73,980,176 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5391:Tns1
|
UTSW |
1 |
74,029,568 (GRCm39) |
splice site |
probably null |
|
|
R5587:Tns1
|
UTSW |
1 |
73,959,755 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5735:Tns1
|
UTSW |
1 |
73,967,138 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5855:Tns1
|
UTSW |
1 |
73,957,192 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5999:Tns1
|
UTSW |
1 |
73,967,256 (GRCm39) |
nonsense |
probably null |
|
|
R6122:Tns1
|
UTSW |
1 |
73,991,578 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6148:Tns1
|
UTSW |
1 |
73,992,612 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6457:Tns1
|
UTSW |
1 |
73,957,209 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6525:Tns1
|
UTSW |
1 |
73,992,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6712:Tns1
|
UTSW |
1 |
74,118,460 (GRCm39) |
nonsense |
probably null |
|
|
R6773:Tns1
|
UTSW |
1 |
73,958,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6825:Tns1
|
UTSW |
1 |
74,041,482 (GRCm39) |
nonsense |
probably null |
|
|
R7085:Tns1
|
UTSW |
1 |
73,964,621 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7128:Tns1
|
UTSW |
1 |
74,034,463 (GRCm39) |
missense |
|
|
|
R7209:Tns1
|
UTSW |
1 |
73,993,074 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7348:Tns1
|
UTSW |
1 |
73,956,076 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7570:Tns1
|
UTSW |
1 |
73,992,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7670:Tns1
|
UTSW |
1 |
73,991,636 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7769:Tns1
|
UTSW |
1 |
73,992,530 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7833:Tns1
|
UTSW |
1 |
74,130,490 (GRCm39) |
intron |
probably benign |
|
|
R8052:Tns1
|
UTSW |
1 |
73,992,596 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8225:Tns1
|
UTSW |
1 |
74,025,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8244:Tns1
|
UTSW |
1 |
73,976,410 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8321:Tns1
|
UTSW |
1 |
74,024,939 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8344:Tns1
|
UTSW |
1 |
74,024,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8378:Tns1
|
UTSW |
1 |
73,976,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8434:Tns1
|
UTSW |
1 |
73,964,765 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8773:Tns1
|
UTSW |
1 |
73,976,407 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9211:Tns1
|
UTSW |
1 |
73,956,948 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9251:Tns1
|
UTSW |
1 |
74,030,855 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9315:Tns1
|
UTSW |
1 |
73,980,141 (GRCm39) |
missense |
|
|
|
R9411:Tns1
|
UTSW |
1 |
73,992,662 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9592:Tns1
|
UTSW |
1 |
74,029,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9658:Tns1
|
UTSW |
1 |
73,981,183 (GRCm39) |
missense |
probably benign |
0.08 |
|
Z1177:Tns1
|
UTSW |
1 |
74,041,466 (GRCm39) |
missense |
probably benign |
0.12 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGATGCCCAATGGACTCTGC -3'
(R):5'- GTTTGAGCTAAGTTGGGAACAG -3'
Sequencing Primer
(F):5'- AATGGACTCTGCTCCCTGCTG -3'
(R):5'- ATGTGGCCCACTCCAGTTCAG -3'
|
| Posted On |
2022-11-14 |
Incidental Mutation