Mutagenetix > Incidental Mutation

Incidental Mutation 'R9694:Ptprz1'

735946

Institutional Source

Beutler Lab

Gene Symbol

Ptprz1

Ensembl Gene

ENSMUSG00000068748

Gene Name

protein tyrosine phosphatase receptor type Z, polypeptide 1

Synonyms

DSD-1-PG, phosphacan, Ptprz, Ptpz, PTPzeta, Rptpbeta, RPTPz, PTPbeta

MMRRC Submission

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.715) question?

Stock #

R9694 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

22875501-23052915 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 22959694 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Phenylalanine at position 64 (I64F)

Ref Sequence

ENSEMBL: ENSMUSP00000088056 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000090568] [ENSMUST00000202102] [ENSMUST00000202579]

AlphaFold

B9EKR1

Predicted Effect

probably damaging
Transcript: ENSMUST00000090568
AA Change: I64F

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000088056
Gene: ENSMUSG00000068748
AA Change: I64F

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
Carb_anhydrase	38	300	5.12e-99	SMART
FN3	312	397	5.53e-4	SMART
low complexity region	588	609	N/A	INTRINSIC
low complexity region	825	837	N/A	INTRINSIC
low complexity region	1417	1441	N/A	INTRINSIC
low complexity region	1485	1495	N/A	INTRINSIC
Blast:PTPc	1497	1573	1e-12	BLAST
low complexity region	1606	1620	N/A	INTRINSIC
transmembrane domain	1637	1659	N/A	INTRINSIC
low complexity region	1679	1693	N/A	INTRINSIC
PTPc	1720	1991	2.8e-130	SMART
PTPc	2019	2281	1.65e-77	SMART

Predicted Effect

unknown
Transcript: ENSMUST00000202102
AA Change: I64F

SMART Domains

Protein: ENSMUSP00000143902
Gene: ENSMUSG00000068748
AA Change: I64F

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
Carb_anhydrase	38	300	5.12e-99	SMART
FN3	312	397	5.53e-4	SMART
low complexity region	588	609	N/A	INTRINSIC
transmembrane domain	788	810	N/A	INTRINSIC
low complexity region	830	844	N/A	INTRINSIC
PTPc	871	1142	2.8e-130	SMART
PTPc	1170	1432	1.65e-77	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000202579
AA Change: I64F

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000144605
Gene: ENSMUSG00000068748
AA Change: I64F

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
Carb_anhydrase	38	300	4e-103	SMART
FN3	312	397	2.8e-6	SMART
low complexity region	588	609	N/A	INTRINSIC
low complexity region	825	837	N/A	INTRINSIC
low complexity region	1417	1441	N/A	INTRINSIC
low complexity region	1485	1495	N/A	INTRINSIC

Coding Region Coverage

1x: 99.8%
3x: 99.7%
10x: 99.3%
20x: 98.7%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
PHENOTYPE: Mice homozygous for targeted null mutations demonstrate an impaired ability to recover from inflamatory lesions of the CNS or gastric mucosa. Mice homozygous for a knock-out allele exhibit increased tactile and thermal nociception thresholds. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 77 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb1b	T	A	5: 8,899,573 (GRCm39)	Y948N	probably damaging	Het
Adamts2	A	G	11: 50,558,972 (GRCm39)	D229G	probably benign	Het
Adamts4	T	C	1: 171,081,530 (GRCm39)	S395P	probably benign	Het
Adcy1	T	C	11: 7,094,774 (GRCm39)	Y567H	probably damaging	Het
Agap3	A	G	5: 24,682,139 (GRCm39)	N212D	probably benign	Het
Atp2a2	A	G	5: 122,597,708 (GRCm39)	F775S	probably damaging	Het
Baz1b	A	T	5: 135,273,094 (GRCm39)	Q1406L	probably benign	Het
C030006K11Rik	A	T	15: 76,607,928 (GRCm39)	V30D	possibly damaging	Het
Cep170b	T	A	12: 112,701,993 (GRCm39)	V262E	probably damaging	Het
Cgnl1	C	T	9: 71,632,803 (GRCm39)	G183R	probably benign	Het
Chd8	A	G	14: 52,441,341 (GRCm39)	I2257T	possibly damaging	Het
Chrna7	A	G	7: 62,754,809 (GRCm39)	I266T	probably damaging	Het
Cyp3a25	A	T	5: 145,923,685 (GRCm39)	Y319*	probably null	Het
Dcdc2a	A	T	13: 25,286,340 (GRCm39)	I125F	probably benign	Het
Dcdc2c	A	T	12: 28,585,553 (GRCm39)	I80N		Het
Dmtn	T	C	14: 70,852,732 (GRCm39)		probably null	Het
Dock2	T	C	11: 34,218,054 (GRCm39)	N1172S	probably benign	Het
Dock9	A	G	14: 121,818,791 (GRCm39)	S1564P	probably damaging	Het
Ecel1	T	C	1: 87,080,853 (GRCm39)	I350V	possibly damaging	Het
Eif4enif1	C	T	11: 3,170,384 (GRCm39)	L146F	probably damaging	Het
Ergic1	T	G	17: 26,843,585 (GRCm39)	D59E	probably benign	Het
F2rl2	A	T	13: 95,838,050 (GRCm39)	D365V	possibly damaging	Het
Fbxl16	C	T	17: 26,036,813 (GRCm39)	Q265*	probably null	Het
Fbxw26	T	C	9: 109,575,135 (GRCm39)		probably benign	Het
Fras1	A	T	5: 96,929,545 (GRCm39)	Y3983F	probably benign	Het
G6pd2	T	A	5: 61,966,460 (GRCm39)	D78E	probably benign	Het
Gas2l2	A	C	11: 83,314,170 (GRCm39)	S381A	possibly damaging	Het
Gm57858	A	G	3: 36,073,092 (GRCm39)	S397P	possibly damaging	Het
Grk2	G	A	19: 4,338,511 (GRCm39)	R474C	probably damaging	Het
Gxylt2	T	A	6: 100,710,174 (GRCm39)	V105E	probably benign	Het
Hexd	T	C	11: 121,107,813 (GRCm39)	V181A	probably damaging	Het
Ift70a2	T	C	2: 75,807,691 (GRCm39)	T274A	probably benign	Het
Ik	T	A	18: 36,877,840 (GRCm39)	D5E	probably benign	Het
Ilkap	A	G	1: 91,303,973 (GRCm39)	C163R		Het
Itpr3	C	T	17: 27,334,927 (GRCm39)	T2147I	probably damaging	Het
Kif1a	A	T	1: 92,950,173 (GRCm39)	V1418E	probably benign	Het
Kif26b	T	C	1: 178,743,815 (GRCm39)	C1304R	probably benign	Het
Lmna	CAGCACGGTGCGTGAGC	CAGC	3: 88,389,857 (GRCm39)		probably null	Het
Lvrn	A	T	18: 47,033,609 (GRCm39)	D940V	probably damaging	Het
Mill1	G	A	7: 17,997,027 (GRCm39)	R206H	probably benign	Het
Mrgpra1	A	T	7: 46,985,268 (GRCm39)	L137Q	probably damaging	Het
Npc2	C	A	12: 84,807,638 (GRCm39)	L73F	probably benign	Het
Or11g26	A	G	14: 50,752,669 (GRCm39)	T3A	probably benign	Het
Or52i2	A	T	7: 102,320,011 (GRCm39)	I295F	possibly damaging	Het
Or5al1	T	C	2: 85,990,681 (GRCm39)	E11G	probably benign	Het
Or5b97	A	T	19: 12,879,021 (GRCm39)	V41E	probably damaging	Het
Or5j3	T	C	2: 86,128,718 (GRCm39)	I186T	probably benign	Het
Osbpl1a	T	C	18: 12,952,565 (GRCm39)	H533R	probably benign	Het
Pax7	G	A	4: 139,556,819 (GRCm39)	T147M	probably benign	Het
Pdik1l	A	T	4: 134,006,711 (GRCm39)	S143T	unknown	Het
Prkg1	T	G	19: 30,764,371 (GRCm39)	T255P	possibly damaging	Het
Prmt2	A	T	10: 76,061,213 (GRCm39)	I91N	probably damaging	Het
Ptprm	A	G	17: 67,116,484 (GRCm39)	Y932H	probably damaging	Het
Qrich2	T	C	11: 116,337,946 (GRCm39)	K154R	probably damaging	Het
Rab8b	T	C	9: 66,826,824 (GRCm39)	D31G	probably benign	Het
Radil	A	G	5: 142,473,378 (GRCm39)	S768P	probably damaging	Het
Rbm5	A	T	9: 107,622,152 (GRCm39)	D607E	probably benign	Het
Reep6	T	A	10: 80,169,393 (GRCm39)	V131E	probably damaging	Het
Rrbp1	T	A	2: 143,832,099 (GRCm39)	I23F	probably damaging	Het
Rubcn	A	T	16: 32,663,481 (GRCm39)	V385D	probably benign	Het
Sall2	C	T	14: 52,552,124 (GRCm39)	G357D	possibly damaging	Het
Slc12a6	T	A	2: 112,174,881 (GRCm39)	L547H	probably damaging	Het
Slc16a6	T	C	11: 109,354,322 (GRCm39)	T100A	probably benign	Het
Sptbn2	T	C	19: 4,800,535 (GRCm39)	L2250P	probably damaging	Het
Stab1	C	T	14: 30,876,901 (GRCm39)	A808T	probably benign	Het
Stag1	A	G	9: 100,810,151 (GRCm39)	T785A	probably benign	Het
Stambpl1	T	G	19: 34,211,535 (GRCm39)	S199A	probably benign	Het
Styxl2	A	T	1: 165,928,654 (GRCm39)	S319R	probably damaging	Het
Supt20	C	T	3: 54,623,015 (GRCm39)	S496L	probably benign	Het
Tanc1	T	C	2: 59,626,196 (GRCm39)	F518L	probably damaging	Het
Tdpoz3	T	A	3: 93,734,156 (GRCm39)	V277D	probably benign	Het
Unc45a	A	C	7: 79,975,403 (GRCm39)	Y934D	probably damaging	Het
Vmn1r192	G	A	13: 22,372,119 (GRCm39)	P34S	probably benign	Het
Wipf3	T	C	6: 54,466,004 (GRCm39)	S421P	possibly damaging	Het
Zfp296	A	G	7: 19,314,227 (GRCm39)	K361E	possibly damaging	Het
Zfp882	T	A	8: 72,667,915 (GRCm39)	N247K	probably benign	Het
Zfpm2	A	G	15: 40,965,710 (GRCm39)	T732A	possibly damaging	Het

Other mutations in Ptprz1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00486:Ptprz1	APN	6	22,973,053 (GRCm39)	missense	probably damaging	1.00
IGL00773:Ptprz1	APN	6	23,002,628 (GRCm39)	missense	probably benign	0.41
IGL01458:Ptprz1	APN	6	22,972,843 (GRCm39)	missense	probably damaging	0.99
IGL01481:Ptprz1	APN	6	22,999,979 (GRCm39)	missense	probably benign	0.05
IGL01501:Ptprz1	APN	6	22,973,081 (GRCm39)	missense	probably damaging	1.00
IGL01601:Ptprz1	APN	6	23,000,437 (GRCm39)	missense	probably damaging	0.99
IGL01882:Ptprz1	APN	6	23,000,463 (GRCm39)	missense	probably damaging	1.00
IGL02058:Ptprz1	APN	6	23,002,502 (GRCm39)	missense	probably benign	0.00
IGL02089:Ptprz1	APN	6	23,033,447 (GRCm39)	missense	probably damaging	1.00
IGL02136:Ptprz1	APN	6	22,972,821 (GRCm39)	missense	probably damaging	1.00
IGL02215:Ptprz1	APN	6	22,965,181 (GRCm39)	missense	possibly damaging	0.91
IGL02220:Ptprz1	APN	6	23,042,742 (GRCm39)	splice site	probably benign
IGL02556:Ptprz1	APN	6	22,972,844 (GRCm39)	missense	probably benign	0.01
IGL02601:Ptprz1	APN	6	23,000,686 (GRCm39)	missense	probably benign	0.11
IGL02620:Ptprz1	APN	6	22,959,739 (GRCm39)	missense	probably damaging	1.00
IGL02666:Ptprz1	APN	6	23,001,209 (GRCm39)	missense	probably benign	0.00
IGL02718:Ptprz1	APN	6	23,001,348 (GRCm39)	missense	possibly damaging	0.77
IGL02792:Ptprz1	APN	6	22,959,722 (GRCm39)	missense	probably damaging	1.00
IGL02894:Ptprz1	APN	6	23,035,148 (GRCm39)	missense	probably damaging	1.00
IGL02952:Ptprz1	APN	6	23,036,925 (GRCm39)	missense	probably damaging	1.00
IGL03003:Ptprz1	APN	6	23,002,582 (GRCm39)	missense	probably damaging	0.98
IGL03060:Ptprz1	APN	6	22,972,834 (GRCm39)	missense	probably damaging	1.00
IGL03170:Ptprz1	APN	6	22,959,766 (GRCm39)	missense	probably benign	0.00
IGL03246:Ptprz1	APN	6	22,986,159 (GRCm39)	missense	probably damaging	0.99
IGL03349:Ptprz1	APN	6	23,000,331 (GRCm39)	missense	probably damaging	1.00
IGL03365:Ptprz1	APN	6	23,030,581 (GRCm39)	splice site	probably benign
Elevator	UTSW	6	23,030,661 (GRCm39)	missense	probably benign	0.03
escalator	UTSW	6	22,986,187 (GRCm39)	missense	probably damaging	1.00
R0044:Ptprz1	UTSW	6	23,007,402 (GRCm39)	missense	probably damaging	1.00
R0054:Ptprz1	UTSW	6	22,986,195 (GRCm39)	missense	probably damaging	1.00
R0054:Ptprz1	UTSW	6	22,986,195 (GRCm39)	missense	probably damaging	1.00
R0107:Ptprz1	UTSW	6	23,000,569 (GRCm39)	missense	probably damaging	0.98
R0278:Ptprz1	UTSW	6	23,000,816 (GRCm39)	missense	probably benign	0.31
R0345:Ptprz1	UTSW	6	23,016,164 (GRCm39)	missense	probably damaging	1.00
R0359:Ptprz1	UTSW	6	22,973,175 (GRCm39)	splice site	probably benign
R0743:Ptprz1	UTSW	6	23,044,366 (GRCm39)	nonsense	probably null
R1014:Ptprz1	UTSW	6	23,000,643 (GRCm39)	missense	probably damaging	1.00
R1016:Ptprz1	UTSW	6	23,000,973 (GRCm39)	missense	probably damaging	1.00
R1106:Ptprz1	UTSW	6	22,965,748 (GRCm39)	missense	probably damaging	0.99
R1391:Ptprz1	UTSW	6	23,001,728 (GRCm39)	missense	probably benign	0.33
R1424:Ptprz1	UTSW	6	23,000,382 (GRCm39)	missense	probably benign	0.00
R1445:Ptprz1	UTSW	6	23,050,473 (GRCm39)	missense	probably damaging	1.00
R1496:Ptprz1	UTSW	6	23,049,523 (GRCm39)	splice site	probably benign
R1544:Ptprz1	UTSW	6	23,000,747 (GRCm39)	missense	possibly damaging	0.63
R1626:Ptprz1	UTSW	6	23,001,573 (GRCm39)	missense	probably benign
R1641:Ptprz1	UTSW	6	23,049,605 (GRCm39)	missense	probably damaging	1.00
R1757:Ptprz1	UTSW	6	23,044,319 (GRCm39)	missense	probably damaging	1.00
R1812:Ptprz1	UTSW	6	22,959,711 (GRCm39)	missense	probably benign	0.07
R1917:Ptprz1	UTSW	6	23,035,039 (GRCm39)	splice site	probably benign
R1930:Ptprz1	UTSW	6	23,007,354 (GRCm39)	missense	probably damaging	1.00
R1931:Ptprz1	UTSW	6	23,007,354 (GRCm39)	missense	probably damaging	1.00
R1974:Ptprz1	UTSW	6	22,986,310 (GRCm39)	missense	probably damaging	1.00
R1992:Ptprz1	UTSW	6	22,959,747 (GRCm39)	missense	probably benign	0.24
R1997:Ptprz1	UTSW	6	23,050,496 (GRCm39)	missense	probably damaging	0.99
R2002:Ptprz1	UTSW	6	23,027,833 (GRCm39)	nonsense	probably null
R2012:Ptprz1	UTSW	6	23,001,026 (GRCm39)	missense	probably benign	0.03
R2059:Ptprz1	UTSW	6	22,986,322 (GRCm39)	splice site	probably benign
R2061:Ptprz1	UTSW	6	23,049,674 (GRCm39)	critical splice donor site	probably null
R2064:Ptprz1	UTSW	6	23,050,388 (GRCm39)	splice site	probably benign
R2067:Ptprz1	UTSW	6	23,050,388 (GRCm39)	splice site	probably benign
R2108:Ptprz1	UTSW	6	23,033,476 (GRCm39)	missense	probably damaging	0.99
R2152:Ptprz1	UTSW	6	23,030,670 (GRCm39)	missense	probably damaging	0.99
R2166:Ptprz1	UTSW	6	23,045,632 (GRCm39)	missense	possibly damaging	0.90
R2183:Ptprz1	UTSW	6	23,002,284 (GRCm39)	missense	probably benign
R2202:Ptprz1	UTSW	6	23,000,649 (GRCm39)	missense	possibly damaging	0.63
R2238:Ptprz1	UTSW	6	22,987,376 (GRCm39)	missense	probably damaging	1.00
R2290:Ptprz1	UTSW	6	23,000,990 (GRCm39)	missense	probably damaging	1.00
R3027:Ptprz1	UTSW	6	23,016,196 (GRCm39)	missense	possibly damaging	0.89
R3861:Ptprz1	UTSW	6	23,036,894 (GRCm39)	missense	probably damaging	0.98
R4012:Ptprz1	UTSW	6	23,002,584 (GRCm39)	missense	probably damaging	0.99
R4020:Ptprz1	UTSW	6	22,959,623 (GRCm39)	splice site	probably benign
R4158:Ptprz1	UTSW	6	23,022,204 (GRCm39)	missense	possibly damaging	0.73
R4158:Ptprz1	UTSW	6	23,001,683 (GRCm39)	nonsense	probably null
R4159:Ptprz1	UTSW	6	23,001,683 (GRCm39)	nonsense	probably null
R4160:Ptprz1	UTSW	6	23,022,204 (GRCm39)	missense	possibly damaging	0.73
R4606:Ptprz1	UTSW	6	23,001,486 (GRCm39)	missense	possibly damaging	0.80
R4621:Ptprz1	UTSW	6	23,001,453 (GRCm39)	missense	possibly damaging	0.68
R4640:Ptprz1	UTSW	6	22,972,797 (GRCm39)	missense	probably damaging	1.00
R4731:Ptprz1	UTSW	6	23,002,609 (GRCm39)	missense	probably benign	0.06
R4732:Ptprz1	UTSW	6	23,002,609 (GRCm39)	missense	probably benign	0.06
R4733:Ptprz1	UTSW	6	23,002,609 (GRCm39)	missense	probably benign	0.06
R4803:Ptprz1	UTSW	6	23,001,545 (GRCm39)	missense	probably benign	0.00
R4890:Ptprz1	UTSW	6	23,024,957 (GRCm39)	missense	probably damaging	1.00
R5035:Ptprz1	UTSW	6	23,016,214 (GRCm39)	missense	probably benign	0.06
R5052:Ptprz1	UTSW	6	23,045,625 (GRCm39)	missense	probably damaging	1.00
R5106:Ptprz1	UTSW	6	23,000,027 (GRCm39)	missense	probably benign	0.04
R5248:Ptprz1	UTSW	6	23,001,900 (GRCm39)	missense	probably benign	0.11
R5292:Ptprz1	UTSW	6	23,002,581 (GRCm39)	missense	probably benign	0.31
R5373:Ptprz1	UTSW	6	23,007,354 (GRCm39)	missense	probably damaging	1.00
R5374:Ptprz1	UTSW	6	23,007,354 (GRCm39)	missense	probably damaging	1.00
R5378:Ptprz1	UTSW	6	23,007,401 (GRCm39)	missense	probably damaging	1.00
R5408:Ptprz1	UTSW	6	23,002,599 (GRCm39)	missense	probably damaging	1.00
R5479:Ptprz1	UTSW	6	23,001,665 (GRCm39)	missense	probably benign
R5524:Ptprz1	UTSW	6	22,986,317 (GRCm39)	splice site	probably null
R5527:Ptprz1	UTSW	6	23,000,052 (GRCm39)	missense	possibly damaging	0.66
R5557:Ptprz1	UTSW	6	23,001,000 (GRCm39)	missense	probably benign	0.04
R5654:Ptprz1	UTSW	6	22,986,133 (GRCm39)	missense	probably damaging	1.00
R5655:Ptprz1	UTSW	6	22,999,772 (GRCm39)	missense	probably benign	0.00
R5658:Ptprz1	UTSW	6	23,016,188 (GRCm39)	missense	probably damaging	1.00
R5663:Ptprz1	UTSW	6	23,035,142 (GRCm39)	missense	probably damaging	1.00
R5765:Ptprz1	UTSW	6	23,000,235 (GRCm39)	missense	probably damaging	1.00
R5822:Ptprz1	UTSW	6	23,001,444 (GRCm39)	missense	probably benign	0.01
R5837:Ptprz1	UTSW	6	23,001,417 (GRCm39)	missense	probably benign	0.00
R6108:Ptprz1	UTSW	6	23,045,658 (GRCm39)	missense	probably damaging	1.00
R6199:Ptprz1	UTSW	6	23,002,470 (GRCm39)	missense	probably benign	0.01
R6245:Ptprz1	UTSW	6	23,051,989 (GRCm39)	missense	probably damaging	1.00
R6257:Ptprz1	UTSW	6	22,959,639 (GRCm39)	missense	probably damaging	1.00
R6488:Ptprz1	UTSW	6	23,001,516 (GRCm39)	nonsense	probably null
R6606:Ptprz1	UTSW	6	23,002,500 (GRCm39)	missense	probably benign	0.27
R6612:Ptprz1	UTSW	6	23,052,081 (GRCm39)	missense	probably damaging	1.00
R6824:Ptprz1	UTSW	6	23,002,130 (GRCm39)	missense	probably benign	0.05
R6834:Ptprz1	UTSW	6	22,999,632 (GRCm39)	missense	probably benign	0.38
R6836:Ptprz1	UTSW	6	23,030,664 (GRCm39)	nonsense	probably null
R6991:Ptprz1	UTSW	6	23,002,686 (GRCm39)	missense	probably benign	0.00
R7044:Ptprz1	UTSW	6	23,044,345 (GRCm39)	missense	probably damaging	1.00
R7048:Ptprz1	UTSW	6	22,961,622 (GRCm39)	missense	probably benign	0.18
R7225:Ptprz1	UTSW	6	23,000,928 (GRCm39)	missense	possibly damaging	0.61
R7284:Ptprz1	UTSW	6	23,000,097 (GRCm39)	missense	probably damaging	1.00
R7360:Ptprz1	UTSW	6	23,000,906 (GRCm39)	missense	probably damaging	1.00
R7501:Ptprz1	UTSW	6	23,001,746 (GRCm39)	nonsense	probably null
R7515:Ptprz1	UTSW	6	23,022,266 (GRCm39)	missense	probably damaging	1.00
R7538:Ptprz1	UTSW	6	22,999,895 (GRCm39)	missense	possibly damaging	0.81
R7567:Ptprz1	UTSW	6	22,959,779 (GRCm39)	missense	probably damaging	0.97
R7599:Ptprz1	UTSW	6	23,002,518 (GRCm39)	missense	not run
R7611:Ptprz1	UTSW	6	23,001,219 (GRCm39)	missense	probably benign
R7685:Ptprz1	UTSW	6	23,024,977 (GRCm39)	missense	probably damaging	1.00
R7707:Ptprz1	UTSW	6	23,002,295 (GRCm39)	missense	probably benign	0.00
R7733:Ptprz1	UTSW	6	23,000,383 (GRCm39)	missense	probably benign	0.31
R7786:Ptprz1	UTSW	6	23,036,992 (GRCm39)	missense	probably damaging	1.00
R7868:Ptprz1	UTSW	6	23,000,963 (GRCm39)	missense	not run
R7882:Ptprz1	UTSW	6	23,002,256 (GRCm39)	missense	probably benign	0.13
R7968:Ptprz1	UTSW	6	22,959,675 (GRCm39)	missense	probably damaging	0.98
R8024:Ptprz1	UTSW	6	23,042,750 (GRCm39)	missense	probably damaging	1.00
R8157:Ptprz1	UTSW	6	23,002,539 (GRCm39)	missense	probably damaging	1.00
R8159:Ptprz1	UTSW	6	23,001,662 (GRCm39)	missense	probably benign
R8354:Ptprz1	UTSW	6	22,999,614 (GRCm39)	missense	probably damaging	0.99
R8496:Ptprz1	UTSW	6	22,972,797 (GRCm39)	missense	probably damaging	0.96
R8757:Ptprz1	UTSW	6	22,972,716 (GRCm39)	missense	possibly damaging	0.74
R8767:Ptprz1	UTSW	6	22,986,187 (GRCm39)	missense	probably damaging	1.00
R8783:Ptprz1	UTSW	6	23,002,026 (GRCm39)	missense	probably benign	0.00
R8811:Ptprz1	UTSW	6	23,030,661 (GRCm39)	missense	probably benign	0.03
R8817:Ptprz1	UTSW	6	23,007,371 (GRCm39)	missense	probably damaging	1.00
R8822:Ptprz1	UTSW	6	23,002,588 (GRCm39)	missense	probably damaging	0.98
R8874:Ptprz1	UTSW	6	23,042,747 (GRCm39)	missense
R9009:Ptprz1	UTSW	6	23,001,653 (GRCm39)	missense	possibly damaging	0.94
R9126:Ptprz1	UTSW	6	23,002,334 (GRCm39)	nonsense	probably null
R9201:Ptprz1	UTSW	6	22,972,869 (GRCm39)	critical splice donor site	probably null
R9210:Ptprz1	UTSW	6	23,050,493 (GRCm39)	missense	probably damaging	0.99
R9212:Ptprz1	UTSW	6	23,050,493 (GRCm39)	missense	probably damaging	0.99
R9229:Ptprz1	UTSW	6	22,986,283 (GRCm39)	missense	probably null	0.03
R9279:Ptprz1	UTSW	6	23,002,444 (GRCm39)	missense	probably benign
R9336:Ptprz1	UTSW	6	23,000,855 (GRCm39)	missense	probably benign	0.01
R9372:Ptprz1	UTSW	6	23,045,706 (GRCm39)	missense	probably damaging	1.00
R9577:Ptprz1	UTSW	6	23,002,202 (GRCm39)	missense	probably damaging	1.00
R9594:Ptprz1	UTSW	6	23,025,026 (GRCm39)	missense	probably damaging	0.98
R9632:Ptprz1	UTSW	6	23,007,292 (GRCm39)	missense	probably damaging	1.00
R9636:Ptprz1	UTSW	6	22,999,994 (GRCm39)	missense	probably benign
R9657:Ptprz1	UTSW	6	23,042,377 (GRCm39)	missense	possibly damaging	0.92
R9716:Ptprz1	UTSW	6	22,959,650 (GRCm39)	missense	probably damaging	1.00
R9794:Ptprz1	UTSW	6	23,000,204 (GRCm39)	missense	probably benign	0.00
Z1176:Ptprz1	UTSW	6	23,051,994 (GRCm39)	missense	probably damaging	0.99
Z1177:Ptprz1	UTSW	6	23,052,023 (GRCm39)	missense	probably damaging	1.00
Z1177:Ptprz1	UTSW	6	22,999,839 (GRCm39)	missense	possibly damaging	0.51

Predicted Primers

PCR Primer
(F):5'- TGAGGCATTTAAAACCCAGCC -3'
(R):5'- GGCCTCTGTTCAGTTCCTAG -3'

Sequencing Primer
(F):5'- GGCATTTAAAACCCAGCCTCTAATC -3'
(R):5'- TCTGTTCAGTTCCTAGCATATTATTG -3'

Posted On

2022-11-14