Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01318:Vmn2r113'

73921

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r113

Ensembl Gene

ENSMUSG00000092111

Gene Name

vomeronasal 2, receptor 113

Synonyms

EG434701

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.135) question?

Stock #

IGL01318

Quality Score

Status

Chromosome

Chromosomal Location

23162158-23177788 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 23177309 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Valine at position 698 (I698V)

Ref Sequence

ENSEMBL: ENSMUSP00000127981 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000170322]

AlphaFold

E9PZA6

Predicted Effect

probably benign
Transcript: ENSMUST00000170322
AA Change: I698V

PolyPhen 2 Score 0.012 (Sensitivity: 0.96; Specificity: 0.78)

SMART Domains

Protein: ENSMUSP00000127981
Gene: ENSMUSG00000092111
AA Change: I698V

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
Pfam:ANF_receptor	146	470	9e-26	PFAM
Pfam:NCD3G	512	564	5.1e-21	PFAM
Pfam:7tm_3	595	832	5.7e-56	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 40 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Alg10b	T	C	15: 90,112,592 (GRCm39)		probably benign	Het
Ambn	T	C	5: 88,608,554 (GRCm39)		probably benign	Het
Asap2	A	G	12: 21,297,296 (GRCm39)	D585G	probably null	Het
Chaf1a	G	T	17: 56,366,336 (GRCm39)		probably benign	Het
Ddhd1	A	G	14: 45,854,008 (GRCm39)	S443P	probably damaging	Het
Dlk2	A	G	17: 46,613,390 (GRCm39)	E215G	probably damaging	Het
Efhd2	T	C	4: 141,587,176 (GRCm39)	N202S	probably benign	Het
Gkap1	A	T	13: 58,384,853 (GRCm39)	I308K	probably damaging	Het
Gm9848	T	A	13: 113,244,774 (GRCm39)		noncoding transcript	Het
Hmcn1	G	A	1: 150,594,991 (GRCm39)	T1826I	probably damaging	Het
Htr5a	T	C	5: 28,047,742 (GRCm39)	V99A	probably benign	Het
Inha	T	G	1: 75,486,572 (GRCm39)	F289C	probably damaging	Het
Kcna3	T	C	3: 106,945,294 (GRCm39)	V519A	probably benign	Het
Kcnma1	A	T	14: 23,364,390 (GRCm39)		probably benign	Het
Kctd1	A	G	18: 15,195,747 (GRCm39)	V292A	possibly damaging	Het
Magea13	T	A	X: 57,964,829 (GRCm39)	I196N	probably damaging	Het
Map2k4	A	G	11: 65,647,089 (GRCm39)		probably benign	Het
Mfap2	G	T	4: 140,742,856 (GRCm39)	A175S	possibly damaging	Het
Milr1	G	A	11: 106,656,071 (GRCm39)	A114T	possibly damaging	Het
Mogs	G	T	6: 83,095,558 (GRCm39)	V792F	probably damaging	Het
Nt5dc3	T	A	10: 86,661,089 (GRCm39)	M418K	possibly damaging	Het
Or5b12	A	G	19: 12,897,490 (GRCm39)	L61P	probably damaging	Het
Or7d10	A	G	9: 19,832,054 (GRCm39)	E183G	probably benign	Het
Or8h8	A	T	2: 86,753,293 (GRCm39)	N194K	probably benign	Het
Osbpl10	G	A	9: 115,061,190 (GRCm39)	W756*	probably null	Het
Pgam5	A	G	5: 110,413,391 (GRCm39)	Y235H	probably damaging	Het
Pgm5	G	T	19: 24,793,842 (GRCm39)	A274E	probably damaging	Het
Prex1	C	A	2: 166,411,260 (GRCm39)		probably benign	Het
Prps1l1	A	T	12: 35,035,377 (GRCm39)	N164I	probably benign	Het
Ralbp1	C	A	17: 66,171,277 (GRCm39)	R232L	probably damaging	Het
Rnaseh2a	C	T	8: 85,691,752 (GRCm39)		probably benign	Het
Stard9	A	T	2: 120,529,200 (GRCm39)	H1819L	possibly damaging	Het
Stom	T	A	2: 35,226,889 (GRCm39)	I15F	probably benign	Het
Tasor2	A	C	13: 3,625,067 (GRCm39)	S946A	possibly damaging	Het
Tph1	T	G	7: 46,314,662 (GRCm39)	T22P	probably damaging	Het
Uqcrfs1	A	G	13: 30,724,904 (GRCm39)	I212T	probably benign	Het
Ush2a	T	C	1: 188,546,550 (GRCm39)	I3442T	probably benign	Het
Vinac1	C	A	2: 128,880,622 (GRCm39)	V435L	probably benign	Het
Vmn2r75	T	C	7: 85,814,774 (GRCm39)	I240V	probably benign	Het
Wdr17	T	C	8: 55,125,585 (GRCm39)	T432A	probably damaging	Het

Other mutations in Vmn2r113

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01386:Vmn2r113	APN	17	23,175,024 (GRCm39)	missense	possibly damaging	0.94
IGL01743:Vmn2r113	APN	17	23,177,285 (GRCm39)	missense	probably benign	0.03
IGL02224:Vmn2r113	APN	17	23,174,960 (GRCm39)	nonsense	probably null
IGL02498:Vmn2r113	APN	17	23,177,349 (GRCm39)	missense	probably damaging	0.99
IGL02969:Vmn2r113	APN	17	23,177,591 (GRCm39)	missense	probably benign	0.13
IGL03010:Vmn2r113	APN	17	23,175,038 (GRCm39)	missense	possibly damaging	0.90
IGL03240:Vmn2r113	APN	17	23,174,931 (GRCm39)	missense	probably benign	0.19
R1853:Vmn2r113	UTSW	17	23,164,501 (GRCm39)	missense	probably benign
R2058:Vmn2r113	UTSW	17	23,177,223 (GRCm39)	nonsense	probably null
R3010:Vmn2r113	UTSW	17	23,177,105 (GRCm39)	missense	probably damaging	0.97
R4942:Vmn2r113	UTSW	17	23,177,321 (GRCm39)	missense	probably damaging	0.97
R5072:Vmn2r113	UTSW	17	23,177,329 (GRCm39)	nonsense	probably null
R5755:Vmn2r113	UTSW	17	23,176,955 (GRCm39)	missense	probably benign	0.00
R6513:Vmn2r113	UTSW	17	23,177,715 (GRCm39)	missense	probably damaging	0.99
R7164:Vmn2r113	UTSW	17	23,167,137 (GRCm39)	missense	probably benign
R7936:Vmn2r113	UTSW	17	23,176,917 (GRCm39)	missense	probably benign	0.05
R8087:Vmn2r113	UTSW	17	23,177,711 (GRCm39)	missense	possibly damaging	0.66
R8193:Vmn2r113	UTSW	17	23,164,501 (GRCm39)	missense	probably benign	0.06
R8196:Vmn2r113	UTSW	17	23,176,938 (GRCm39)	missense	probably damaging	0.99
R8414:Vmn2r113	UTSW	17	23,177,753 (GRCm39)	nonsense	probably null
R8490:Vmn2r113	UTSW	17	23,177,372 (GRCm39)	missense	probably benign	0.18

Posted On

2013-10-07