Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL01318:Vmn2r113'

73921

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r113

Ensembl Gene

ENSMUSG00000092111

Gene Name

vomeronasal 2, receptor 113

Synonyms

EG434701

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.135) question?

Stock #

IGL01318

Quality Score

Status

Chromosome

Chromosomal Location

22943184-22958814 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 22958335 bp

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Valine at position 698 (I698V)

Ref Sequence

ENSEMBL: ENSMUSP00000127981 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000170322]

Predicted Effect

probably benign
Transcript: ENSMUST00000170322
AA Change: I698V

PolyPhen 2 Score 0.012 (Sensitivity: 0.96; Specificity: 0.78)

SMART Domains

Protein: ENSMUSP00000127981
Gene: ENSMUSG00000092111
AA Change: I698V

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
Pfam:ANF_receptor	146	470	9e-26	PFAM
Pfam:NCD3G	512	564	5.1e-21	PFAM
Pfam:7tm_3	595	832	5.7e-56	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 40 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930550L24Rik	T	A	X: 58,919,469	I196N	probably damaging	Het
Alg10b	T	C	15: 90,228,389		probably benign	Het
Ambn	T	C	5: 88,460,695		probably benign	Het
Asap2	A	G	12: 21,247,295	D585G	probably null	Het
Chaf1a	G	T	17: 56,059,336		probably benign	Het
Ddhd1	A	G	14: 45,616,551	S443P	probably damaging	Het
Dlk2	A	G	17: 46,302,464	E215G	probably damaging	Het
Efhd2	T	C	4: 141,859,865	N202S	probably benign	Het
Fam208b	A	C	13: 3,575,067	S946A	possibly damaging	Het
Gkap1	A	T	13: 58,237,039	I308K	probably damaging	Het
Gm14025	C	A	2: 129,038,702	V435L	probably benign	Het
Gm9848	T	A	13: 113,108,240		noncoding transcript	Het
Hmcn1	G	A	1: 150,719,240	T1826I	probably damaging	Het
Htr5a	T	C	5: 27,842,744	V99A	probably benign	Het
Inha	T	G	1: 75,509,928	F289C	probably damaging	Het
Kcna3	T	C	3: 107,037,978	V519A	probably benign	Het
Kcnma1	A	T	14: 23,314,322		probably benign	Het
Kctd1	A	G	18: 15,062,690	V292A	possibly damaging	Het
Map2k4	A	G	11: 65,756,263		probably benign	Het
Mfap2	G	T	4: 141,015,545	A175S	possibly damaging	Het
Milr1	G	A	11: 106,765,245	A114T	possibly damaging	Het
Mogs	G	T	6: 83,118,577	V792F	probably damaging	Het
Nt5dc3	T	A	10: 86,825,225	M418K	possibly damaging	Het
Olfr1098	A	T	2: 86,922,949	N194K	probably benign	Het
Olfr1448	A	G	19: 12,920,126	L61P	probably damaging	Het
Olfr77	A	G	9: 19,920,758	E183G	probably benign	Het
Osbpl10	G	A	9: 115,232,122	W756*	probably null	Het
Pgam5	A	G	5: 110,265,525	Y235H	probably damaging	Het
Pgm5	G	T	19: 24,816,478	A274E	probably damaging	Het
Prex1	C	A	2: 166,569,340		probably benign	Het
Prps1l1	A	T	12: 34,985,378	N164I	probably benign	Het
Ralbp1	C	A	17: 65,864,282	R232L	probably damaging	Het
Rnaseh2a	C	T	8: 84,965,123		probably benign	Het
Stard9	A	T	2: 120,698,719	H1819L	possibly damaging	Het
Stom	T	A	2: 35,336,877	I15F	probably benign	Het
Tph1	T	G	7: 46,665,238	T22P	probably damaging	Het
Uqcrfs1	A	G	13: 30,540,921	I212T	probably benign	Het
Ush2a	T	C	1: 188,814,353	I3442T	probably benign	Het
Vmn2r75	T	C	7: 86,165,566	I240V	probably benign	Het
Wdr17	T	C	8: 54,672,550	T432A	probably damaging	Het

Other mutations in Vmn2r113

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01386:Vmn2r113	APN	17	22956050	missense	possibly damaging	0.94
IGL01743:Vmn2r113	APN	17	22958311	missense	probably benign	0.03
IGL02224:Vmn2r113	APN	17	22955986	nonsense	probably null
IGL02498:Vmn2r113	APN	17	22958375	missense	probably damaging	0.99
IGL02969:Vmn2r113	APN	17	22958617	missense	probably benign	0.13
IGL03010:Vmn2r113	APN	17	22956064	missense	possibly damaging	0.90
IGL03240:Vmn2r113	APN	17	22955957	missense	probably benign	0.19
R1853:Vmn2r113	UTSW	17	22945527	missense	probably benign
R2058:Vmn2r113	UTSW	17	22958249	nonsense	probably null
R3010:Vmn2r113	UTSW	17	22958131	missense	probably damaging	0.97
R4942:Vmn2r113	UTSW	17	22958347	missense	probably damaging	0.97
R5072:Vmn2r113	UTSW	17	22958355	nonsense	probably null
R5755:Vmn2r113	UTSW	17	22957981	missense	probably benign	0.00
R6513:Vmn2r113	UTSW	17	22958741	missense	probably damaging	0.99
R7164:Vmn2r113	UTSW	17	22948163	missense	probably benign

Posted On

2013-10-07