Incidental Mutation 'IGL01319:Dock2'
ID 73962
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Dock2
Ensembl Gene ENSMUSG00000020143
Gene Name dedicator of cyto-kinesis 2
Synonyms CED-5, Hch, MBC
Accession Numbers
Essential gene? Non essential (E-score: 0.000) question?
Stock # IGL01319
Quality Score
Status
Chromosome 11
Chromosomal Location 34176815-34674719 bp(-) (GRCm39)
Type of Mutation missense
DNA Base Change (assembly) A to G at 34589617 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change Valine to Alanine at position 480 (V480A)
Ref Sequence ENSEMBL: ENSMUSP00000098916 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000093193] [ENSMUST00000101365] [ENSMUST00000143540]
AlphaFold Q8C3J5
Predicted Effect probably benign
Transcript: ENSMUST00000093193
AA Change: V480A

PolyPhen 2 Score 0.414 (Sensitivity: 0.89; Specificity: 0.90)
SMART Domains Protein: ENSMUSP00000090884
Gene: ENSMUSG00000020143
AA Change: V480A

DomainStartEndE-ValueType
SH3 11 68 1.22e-11 SMART
Pfam:DOCK_N 71 414 2e-113 PFAM
Pfam:DOCK-C2 419 616 1e-60 PFAM
Pfam:DHR-2 1114 1614 6.3e-96 PFAM
low complexity region 1691 1706 N/A INTRINSIC
low complexity region 1793 1800 N/A INTRINSIC
Predicted Effect possibly damaging
Transcript: ENSMUST00000101365
AA Change: V480A

PolyPhen 2 Score 0.608 (Sensitivity: 0.87; Specificity: 0.91)
SMART Domains Protein: ENSMUSP00000098916
Gene: ENSMUSG00000020143
AA Change: V480A

DomainStartEndE-ValueType
SH3 11 68 1.22e-11 SMART
Pfam:DOCK_N 71 414 1.4e-113 PFAM
Pfam:DOCK-C2 419 616 5.5e-61 PFAM
low complexity region 1163 1171 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000143540
AA Change: V480A

PolyPhen 2 Score 0.298 (Sensitivity: 0.91; Specificity: 0.89)
SMART Domains Protein: ENSMUSP00000116893
Gene: ENSMUSG00000020143
AA Change: V480A

DomainStartEndE-ValueType
SH3 11 68 1.22e-11 SMART
Pfam:DOCK-C2 418 617 1.8e-55 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000154178
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. [provided by RefSeq, Oct 2016]
PHENOTYPE: Homozygous mutants are defective in the migration of T and B lympohcytes in response to chemokines, and thus display immune defects such as lymphocytopenia, atrophy of lymphoid follicles and loss of marginal-zone B cells. [provided by MGI curators]
Allele List at MGI
Other mutations in this stock
Total: 43 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abhd18 T A 3: 40,888,077 (GRCm39) V307E probably benign Het
Bub1b T C 2: 118,445,475 (GRCm39) I265T possibly damaging Het
Cemip2 C T 19: 21,822,121 (GRCm39) P1172L possibly damaging Het
Cntnap3 G A 13: 64,935,651 (GRCm39) T404I probably damaging Het
Disc1 T C 8: 125,814,630 (GRCm39) S165P probably damaging Het
Dock1 T C 7: 134,391,007 (GRCm39) F756L probably benign Het
Drc3 A G 11: 60,255,788 (GRCm39) D125G probably null Het
Emid1 C T 11: 5,093,859 (GRCm39) C96Y probably damaging Het
F13b A G 1: 139,434,531 (GRCm39) N99S probably damaging Het
Fam20a A G 11: 109,569,284 (GRCm39) probably benign Het
Fancd2 C A 6: 113,561,860 (GRCm39) T1243K probably damaging Het
Fbxw14 T C 9: 109,107,859 (GRCm39) K172E probably damaging Het
Gm13941 T C 2: 110,925,150 (GRCm39) probably null Het
Gtpbp4 A T 13: 9,035,296 (GRCm39) N354K probably benign Het
Igkv2-116 T C 6: 68,129,388 (GRCm39) L50P probably benign Het
Klrb1-ps1 C T 6: 129,093,548 (GRCm39) P23L possibly damaging Het
Kng2 T A 16: 22,847,584 (GRCm39) I26F probably damaging Het
Krt81 G A 15: 101,361,269 (GRCm39) H104Y probably benign Het
Lrpprc T C 17: 85,012,840 (GRCm39) probably benign Het
Man2a2 C T 7: 80,010,880 (GRCm39) V704M possibly damaging Het
Mbip A G 12: 56,377,027 (GRCm39) V303A probably benign Het
Mipep A T 14: 61,080,720 (GRCm39) M571L probably benign Het
Ncan A T 8: 70,550,212 (GRCm39) V1188D probably damaging Het
Pcdhb4 T C 18: 37,441,566 (GRCm39) V292A probably benign Het
Pkd1 T C 17: 24,806,893 (GRCm39) probably benign Het
Ppp2r2c T A 5: 37,104,465 (GRCm39) S282T possibly damaging Het
Rad54l2 C T 9: 106,596,245 (GRCm39) G231D probably benign Het
Rnf20 T G 4: 49,649,326 (GRCm39) D443E probably damaging Het
Rptor A G 11: 119,781,996 (GRCm39) M1108V probably benign Het
Serpine2 A G 1: 79,788,411 (GRCm39) V182A probably damaging Het
Sesn2 C T 4: 132,227,278 (GRCm39) probably benign Het
Shank1 C A 7: 44,002,547 (GRCm39) A1422E possibly damaging Het
Skic3 A G 13: 76,277,498 (GRCm39) H491R probably benign Het
Slc13a4 C T 6: 35,284,288 (GRCm39) probably null Het
Snrnp200 T C 2: 127,072,047 (GRCm39) probably benign Het
Src G A 2: 157,311,423 (GRCm39) G461R probably damaging Het
Tbxas1 A G 6: 38,994,907 (GRCm39) I178V probably benign Het
Triml1 A G 8: 43,594,434 (GRCm39) probably benign Het
Tsen2 A T 6: 115,553,945 (GRCm39) Q441L probably damaging Het
Ttc23l A G 15: 10,509,492 (GRCm39) probably benign Het
Ttn T C 2: 76,711,648 (GRCm39) probably benign Het
Vsig10l C T 7: 43,114,678 (GRCm39) S293L probably damaging Het
Zcchc13 C A X: 102,674,606 (GRCm39) Q110K possibly damaging Het
Other mutations in Dock2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00334:Dock2 APN 11 34,595,488 (GRCm39) missense probably damaging 1.00
IGL00469:Dock2 APN 11 34,179,603 (GRCm39) splice site probably benign
IGL01061:Dock2 APN 11 34,596,653 (GRCm39) missense probably damaging 1.00
IGL01451:Dock2 APN 11 34,260,390 (GRCm39) missense probably damaging 1.00
IGL01490:Dock2 APN 11 34,596,608 (GRCm39) missense probably damaging 0.97
IGL01601:Dock2 APN 11 34,189,528 (GRCm39) critical splice donor site probably null
IGL01800:Dock2 APN 11 34,647,100 (GRCm39) missense probably damaging 1.00
IGL01804:Dock2 APN 11 34,212,433 (GRCm39) missense probably benign 0.01
IGL01823:Dock2 APN 11 34,212,391 (GRCm39) missense probably damaging 1.00
IGL01829:Dock2 APN 11 34,596,668 (GRCm39) missense probably damaging 0.98
IGL01830:Dock2 APN 11 34,582,744 (GRCm39) nonsense probably null
IGL01835:Dock2 APN 11 34,260,435 (GRCm39) missense possibly damaging 0.51
IGL01845:Dock2 APN 11 34,599,692 (GRCm39) missense probably benign 0.02
IGL01953:Dock2 APN 11 34,623,183 (GRCm39) missense probably benign 0.28
IGL01989:Dock2 APN 11 34,218,053 (GRCm39) missense probably benign
IGL02081:Dock2 APN 11 34,204,355 (GRCm39) missense probably benign
IGL02105:Dock2 APN 11 34,605,352 (GRCm39) missense probably damaging 1.00
IGL02153:Dock2 APN 11 34,180,670 (GRCm39) missense probably benign 0.01
IGL02170:Dock2 APN 11 34,217,949 (GRCm39) missense probably damaging 1.00
IGL02344:Dock2 APN 11 34,622,337 (GRCm39) missense probably damaging 0.98
IGL02389:Dock2 APN 11 34,589,567 (GRCm39) splice site probably benign
IGL02409:Dock2 APN 11 34,451,204 (GRCm39) missense probably benign 0.00
IGL02472:Dock2 APN 11 34,199,801 (GRCm39) missense probably benign 0.00
IGL02625:Dock2 APN 11 34,451,168 (GRCm39) critical splice donor site probably null
IGL02929:Dock2 APN 11 34,218,048 (GRCm39) missense probably damaging 1.00
IGL02951:Dock2 APN 11 34,260,448 (GRCm39) unclassified probably benign
IGL02999:Dock2 APN 11 34,583,086 (GRCm39) missense probably damaging 0.99
IGL03165:Dock2 APN 11 34,578,360 (GRCm39) missense probably damaging 0.99
Arches UTSW 11 34,580,587 (GRCm39) missense probably damaging 1.00
capitol_reef UTSW 11 34,244,170 (GRCm39) critical splice acceptor site probably null
Croesus UTSW 11 34,611,854 (GRCm39) missense probably damaging 1.00
denali UTSW 11 34,179,472 (GRCm39) critical splice donor site probably null
dew UTSW 11 34,198,636 (GRCm39) nonsense probably null
Dinghy UTSW 11 34,212,460 (GRCm39) missense possibly damaging 0.70
Dry UTSW 11 34,181,652 (GRCm39) missense possibly damaging 0.79
frazz UTSW 11 34,198,572 (GRCm39) critical splice donor site probably benign
frizz UTSW 11 34,208,184 (GRCm39) splice site probably benign
gildenstern UTSW 11 34,623,166 (GRCm39) critical splice donor site probably null
godsgrace UTSW 11 34,586,280 (GRCm39) missense probably damaging 1.00
Harborside UTSW 11 34,212,445 (GRCm39) missense probably benign
Landing UTSW 11 34,605,328 (GRCm39) missense possibly damaging 0.83
latest UTSW 11 34,647,049 (GRCm39) missense probably damaging 1.00
Launch UTSW 11 34,206,562 (GRCm39) missense probably damaging 1.00
liaoning UTSW 11 34,599,620 (GRCm39) missense probably damaging 1.00
lucre UTSW 11 34,595,436 (GRCm39) frame shift probably null
midas UTSW 11 34,244,323 (GRCm39) missense probably damaging 0.99
muelle UTSW 11 34,578,365 (GRCm39) missense probably damaging 1.00
narrowest UTSW 11 34,232,652 (GRCm39) missense probably damaging 0.98
pier UTSW 11 34,580,593 (GRCm39) missense probably damaging 1.00
Plank UTSW 11 34,674,622 (GRCm39) missense possibly damaging 0.51
resplendent UTSW 11 34,618,287 (GRCm39) nonsense probably null
riches UTSW 11 34,579,279 (GRCm39) critical splice donor site probably null
skiff UTSW 11 34,212,388 (GRCm39) missense probably null 0.80
Slip UTSW 11 34,244,286 (GRCm39) missense probably benign 0.25
toothskin UTSW 11 34,414,922 (GRCm39) missense probably damaging 1.00
Touch UTSW 11 34,223,750 (GRCm39) missense possibly damaging 0.95
wassup UTSW 11 34,453,413 (GRCm39) missense probably damaging 1.00
Wharf UTSW 11 34,623,198 (GRCm39) missense possibly damaging 0.81
BB009:Dock2 UTSW 11 34,217,998 (GRCm39) missense probably benign 0.00
BB019:Dock2 UTSW 11 34,217,998 (GRCm39) missense probably benign 0.00
IGL03052:Dock2 UTSW 11 34,182,853 (GRCm39) missense probably benign 0.01
PIT4377001:Dock2 UTSW 11 34,611,835 (GRCm39) missense probably benign 0.02
R0006:Dock2 UTSW 11 34,262,453 (GRCm39) unclassified probably benign
R0012:Dock2 UTSW 11 34,674,622 (GRCm39) missense possibly damaging 0.51
R0063:Dock2 UTSW 11 34,647,111 (GRCm39) critical splice acceptor site probably null
R0063:Dock2 UTSW 11 34,647,111 (GRCm39) critical splice acceptor site probably null
R0116:Dock2 UTSW 11 34,579,392 (GRCm39) intron probably benign
R0149:Dock2 UTSW 11 34,388,327 (GRCm39) missense probably damaging 1.00
R0361:Dock2 UTSW 11 34,388,327 (GRCm39) missense probably damaging 1.00
R0462:Dock2 UTSW 11 34,218,052 (GRCm39) missense possibly damaging 0.74
R0471:Dock2 UTSW 11 34,579,380 (GRCm39) missense probably benign 0.30
R0538:Dock2 UTSW 11 34,595,545 (GRCm39) splice site probably benign
R0543:Dock2 UTSW 11 34,244,325 (GRCm39) missense probably damaging 1.00
R0660:Dock2 UTSW 11 34,198,621 (GRCm39) missense probably damaging 1.00
R0676:Dock2 UTSW 11 34,586,063 (GRCm39) missense probably damaging 0.99
R0722:Dock2 UTSW 11 34,414,970 (GRCm39) splice site probably benign
R0801:Dock2 UTSW 11 34,599,620 (GRCm39) missense probably damaging 1.00
R1110:Dock2 UTSW 11 34,206,535 (GRCm39) missense possibly damaging 0.78
R1171:Dock2 UTSW 11 34,586,068 (GRCm39) missense probably damaging 1.00
R1387:Dock2 UTSW 11 34,223,309 (GRCm39) splice site probably benign
R1445:Dock2 UTSW 11 34,189,705 (GRCm39) missense probably benign
R1494:Dock2 UTSW 11 34,232,761 (GRCm39) nonsense probably null
R1589:Dock2 UTSW 11 34,597,288 (GRCm39) missense probably damaging 0.99
R1597:Dock2 UTSW 11 34,595,474 (GRCm39) missense probably benign 0.00
R1629:Dock2 UTSW 11 34,212,480 (GRCm39) splice site probably null
R1749:Dock2 UTSW 11 34,182,767 (GRCm39) critical splice donor site probably null
R1888:Dock2 UTSW 11 34,598,169 (GRCm39) missense probably damaging 1.00
R1888:Dock2 UTSW 11 34,598,169 (GRCm39) missense probably damaging 1.00
R1899:Dock2 UTSW 11 34,244,286 (GRCm39) missense probably benign 0.25
R1924:Dock2 UTSW 11 34,414,934 (GRCm39) missense possibly damaging 0.69
R2031:Dock2 UTSW 11 34,618,297 (GRCm39) splice site probably benign
R2045:Dock2 UTSW 11 34,244,106 (GRCm39) splice site probably null
R2098:Dock2 UTSW 11 34,609,832 (GRCm39) missense probably damaging 0.99
R2098:Dock2 UTSW 11 34,216,279 (GRCm39) missense probably benign 0.16
R2129:Dock2 UTSW 11 34,618,242 (GRCm39) missense probably damaging 1.00
R2147:Dock2 UTSW 11 34,179,472 (GRCm39) critical splice donor site probably null
R2149:Dock2 UTSW 11 34,179,472 (GRCm39) critical splice donor site probably null
R2150:Dock2 UTSW 11 34,179,472 (GRCm39) critical splice donor site probably null
R2176:Dock2 UTSW 11 34,586,044 (GRCm39) missense probably benign 0.00
R2230:Dock2 UTSW 11 34,244,323 (GRCm39) missense probably damaging 0.99
R2508:Dock2 UTSW 11 34,262,485 (GRCm39) missense probably benign 0.04
R2875:Dock2 UTSW 11 34,609,712 (GRCm39) missense probably damaging 1.00
R2885:Dock2 UTSW 11 34,580,593 (GRCm39) missense probably damaging 1.00
R2910:Dock2 UTSW 11 34,182,910 (GRCm39) splice site probably benign
R3081:Dock2 UTSW 11 34,181,610 (GRCm39) missense probably benign
R3418:Dock2 UTSW 11 34,580,587 (GRCm39) missense probably damaging 1.00
R3552:Dock2 UTSW 11 34,611,787 (GRCm39) missense probably benign 0.22
R3731:Dock2 UTSW 11 34,599,722 (GRCm39) missense probably damaging 1.00
R3846:Dock2 UTSW 11 34,623,198 (GRCm39) missense possibly damaging 0.81
R4135:Dock2 UTSW 11 34,605,328 (GRCm39) missense possibly damaging 0.83
R4598:Dock2 UTSW 11 34,189,536 (GRCm39) missense probably damaging 1.00
R4599:Dock2 UTSW 11 34,189,536 (GRCm39) missense probably damaging 1.00
R4715:Dock2 UTSW 11 34,244,118 (GRCm39) missense probably damaging 1.00
R4722:Dock2 UTSW 11 34,586,298 (GRCm39) missense probably damaging 1.00
R4742:Dock2 UTSW 11 34,244,170 (GRCm39) critical splice acceptor site probably null
R4830:Dock2 UTSW 11 34,223,767 (GRCm39) splice site probably null
R4884:Dock2 UTSW 11 34,216,248 (GRCm39) missense probably damaging 1.00
R4990:Dock2 UTSW 11 34,586,078 (GRCm39) missense probably damaging 1.00
R5334:Dock2 UTSW 11 34,178,643 (GRCm39) missense probably benign 0.00
R5570:Dock2 UTSW 11 34,618,233 (GRCm39) missense probably damaging 1.00
R5602:Dock2 UTSW 11 34,204,391 (GRCm39) missense probably benign 0.16
R5681:Dock2 UTSW 11 34,199,836 (GRCm39) missense probably benign 0.06
R5809:Dock2 UTSW 11 34,212,445 (GRCm39) missense probably benign
R5860:Dock2 UTSW 11 34,206,562 (GRCm39) missense probably damaging 1.00
R6111:Dock2 UTSW 11 34,599,614 (GRCm39) missense probably damaging 0.99
R6155:Dock2 UTSW 11 34,244,123 (GRCm39) missense probably benign 0.06
R6156:Dock2 UTSW 11 34,197,789 (GRCm39) missense possibly damaging 0.51
R6173:Dock2 UTSW 11 34,212,388 (GRCm39) missense probably null 0.80
R6182:Dock2 UTSW 11 34,179,476 (GRCm39) missense probably damaging 0.97
R6188:Dock2 UTSW 11 34,453,396 (GRCm39) missense probably damaging 0.98
R6191:Dock2 UTSW 11 34,181,652 (GRCm39) missense possibly damaging 0.79
R6283:Dock2 UTSW 11 34,598,152 (GRCm39) missense probably damaging 0.99
R6395:Dock2 UTSW 11 34,182,874 (GRCm39) missense probably damaging 1.00
R6465:Dock2 UTSW 11 34,453,413 (GRCm39) missense probably damaging 1.00
R6500:Dock2 UTSW 11 34,312,822 (GRCm39) missense possibly damaging 0.76
R6561:Dock2 UTSW 11 34,578,365 (GRCm39) missense probably damaging 1.00
R6745:Dock2 UTSW 11 34,596,670 (GRCm39) missense probably damaging 1.00
R6745:Dock2 UTSW 11 34,596,669 (GRCm39) missense probably damaging 1.00
R6880:Dock2 UTSW 11 34,579,279 (GRCm39) critical splice donor site probably null
R6913:Dock2 UTSW 11 34,647,049 (GRCm39) missense probably damaging 1.00
R6997:Dock2 UTSW 11 34,414,922 (GRCm39) missense probably damaging 1.00
R7057:Dock2 UTSW 11 34,586,044 (GRCm39) missense probably benign 0.00
R7057:Dock2 UTSW 11 34,177,684 (GRCm39) missense probably benign 0.10
R7134:Dock2 UTSW 11 34,260,363 (GRCm39) missense probably benign 0.03
R7188:Dock2 UTSW 11 34,189,675 (GRCm39) missense possibly damaging 0.87
R7239:Dock2 UTSW 11 34,181,677 (GRCm39) missense probably benign 0.00
R7247:Dock2 UTSW 11 34,605,340 (GRCm39) nonsense probably null
R7250:Dock2 UTSW 11 34,586,120 (GRCm39) missense probably damaging 1.00
R7250:Dock2 UTSW 11 34,586,032 (GRCm39) missense probably benign 0.01
R7271:Dock2 UTSW 11 34,223,750 (GRCm39) missense possibly damaging 0.95
R7284:Dock2 UTSW 11 34,180,672 (GRCm39) missense probably benign 0.01
R7397:Dock2 UTSW 11 34,609,816 (GRCm39) missense probably benign 0.00
R7464:Dock2 UTSW 11 34,586,105 (GRCm39) missense probably damaging 0.99
R7512:Dock2 UTSW 11 34,262,542 (GRCm39) missense possibly damaging 0.95
R7556:Dock2 UTSW 11 34,611,778 (GRCm39) missense probably benign 0.43
R7663:Dock2 UTSW 11 34,611,854 (GRCm39) missense probably damaging 1.00
R7779:Dock2 UTSW 11 34,605,282 (GRCm39) missense probably benign 0.38
R7797:Dock2 UTSW 11 34,232,652 (GRCm39) missense probably damaging 0.98
R7855:Dock2 UTSW 11 34,223,698 (GRCm39) missense probably damaging 1.00
R7922:Dock2 UTSW 11 34,598,154 (GRCm39) missense probably benign 0.29
R7932:Dock2 UTSW 11 34,217,998 (GRCm39) missense probably benign 0.00
R8013:Dock2 UTSW 11 34,596,677 (GRCm39) missense probably damaging 0.96
R8192:Dock2 UTSW 11 34,623,166 (GRCm39) critical splice donor site probably null
R8244:Dock2 UTSW 11 34,586,280 (GRCm39) missense probably damaging 1.00
R8307:Dock2 UTSW 11 34,260,362 (GRCm39) missense possibly damaging 0.95
R8418:Dock2 UTSW 11 34,609,795 (GRCm39) missense probably benign 0.01
R8460:Dock2 UTSW 11 34,180,825 (GRCm39) critical splice acceptor site probably null
R8495:Dock2 UTSW 11 34,181,622 (GRCm39) missense probably benign 0.14
R8556:Dock2 UTSW 11 34,212,457 (GRCm39) missense possibly damaging 0.84
R8690:Dock2 UTSW 11 34,618,287 (GRCm39) nonsense probably null
R8743:Dock2 UTSW 11 34,223,252 (GRCm39) nonsense probably null
R8757:Dock2 UTSW 11 34,586,067 (GRCm39) missense probably benign 0.13
R8759:Dock2 UTSW 11 34,586,067 (GRCm39) missense probably benign 0.13
R8793:Dock2 UTSW 11 34,451,215 (GRCm39) missense probably benign 0.00
R8882:Dock2 UTSW 11 34,595,436 (GRCm39) frame shift probably null
R8885:Dock2 UTSW 11 34,260,396 (GRCm39) missense probably benign 0.01
R8943:Dock2 UTSW 11 34,599,646 (GRCm39) missense possibly damaging 0.63
R9171:Dock2 UTSW 11 34,589,670 (GRCm39) missense probably benign 0.12
R9182:Dock2 UTSW 11 34,260,398 (GRCm39) missense possibly damaging 0.51
R9203:Dock2 UTSW 11 34,622,366 (GRCm39) missense possibly damaging 0.92
R9310:Dock2 UTSW 11 34,244,139 (GRCm39) missense possibly damaging 0.71
R9388:Dock2 UTSW 11 34,212,460 (GRCm39) missense possibly damaging 0.70
R9490:Dock2 UTSW 11 34,589,582 (GRCm39) missense possibly damaging 0.90
R9568:Dock2 UTSW 11 34,599,638 (GRCm39) missense possibly damaging 0.83
R9593:Dock2 UTSW 11 34,178,607 (GRCm39) missense probably benign 0.34
R9694:Dock2 UTSW 11 34,218,054 (GRCm39) missense probably benign
R9697:Dock2 UTSW 11 34,204,417 (GRCm39) missense probably benign
R9753:Dock2 UTSW 11 34,223,673 (GRCm39) missense possibly damaging 0.68
R9783:Dock2 UTSW 11 34,208,128 (GRCm39) missense possibly damaging 0.83
X0017:Dock2 UTSW 11 34,216,271 (GRCm39) missense probably benign 0.08
X0018:Dock2 UTSW 11 34,182,833 (GRCm39) missense possibly damaging 0.65
X0058:Dock2 UTSW 11 34,206,564 (GRCm39) missense probably damaging 1.00
X0066:Dock2 UTSW 11 34,260,357 (GRCm39) missense possibly damaging 0.95
Z1088:Dock2 UTSW 11 34,583,209 (GRCm39) missense probably damaging 1.00
Z1088:Dock2 UTSW 11 34,388,300 (GRCm39) missense probably benign 0.14
Z1088:Dock2 UTSW 11 34,586,039 (GRCm39) nonsense probably null
Z1176:Dock2 UTSW 11 34,609,751 (GRCm39) missense probably benign 0.04
Z1177:Dock2 UTSW 11 34,262,553 (GRCm39) missense possibly damaging 0.68
Posted On 2013-10-07