Incidental Mutation 'IGL01322:Sult2a1'
ID74072
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Sult2a1
Ensembl Gene ENSMUSG00000078798
Gene Namesulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
SynonymsStd, Sth1, mSTa1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.080) question?
Stock #IGL01322
Quality Score
Status
Chromosome7
Chromosomal Location13796246-13837409 bp(-) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) T to A at 13832679 bp
ZygosityHeterozygous
Amino Acid Change Arginine to Stop codon at position 124 (R124*)
Ref Sequence ENSEMBL: ENSMUSP00000104162 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000108522]
Predicted Effect probably null
Transcript: ENSMUST00000108522
AA Change: R124*
SMART Domains Protein: ENSMUSP00000104162
Gene: ENSMUSG00000078798
AA Change: R124*

DomainStartEndE-ValueType
Pfam:Sulfotransfer_1 34 278 4.6e-83 PFAM
Pfam:Sulfotransfer_3 35 205 5.8e-11 PFAM
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: This is one of seven sulfotransferase family 2A genes in a chromosome 7 A1 cluster. [provided by RefSeq, May 2010]
Allele List at MGI
Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca16 T A 7: 120,439,199 L368Q probably damaging Het
Abca2 T A 2: 25,446,782 probably null Het
Ano7 T A 1: 93,395,508 V497D probably benign Het
B4gat1 T C 19: 5,040,009 Y345H probably damaging Het
Bckdha T A 7: 25,658,707 R12W possibly damaging Het
Bcl7c T A 7: 127,707,436 N93Y probably damaging Het
Cc2d2a C A 5: 43,689,003 T368K probably benign Het
Chek1 G A 9: 36,718,421 Q210* probably null Het
Chrdl2 A G 7: 100,017,041 Y56C probably damaging Het
Cspg4 T A 9: 56,898,588 F2228I probably damaging Het
Dnah7a T C 1: 53,434,046 M3474V probably benign Het
Dph7 T C 2: 24,965,617 S143P possibly damaging Het
Ehbp1 T A 11: 22,089,636 K821N probably damaging Het
Eomes T C 9: 118,484,830 S648P probably benign Het
Fam20a A G 11: 109,682,912 V215A probably damaging Het
Fer1l4 T A 2: 156,020,339 probably null Het
Frem2 A G 3: 53,541,038 V2319A probably benign Het
Gtf3c4 T C 2: 28,833,572 D575G probably benign Het
Ifit1bl2 A G 19: 34,619,004 V404A probably benign Het
Kcnf1 T C 12: 17,175,348 M291V probably benign Het
Klra1 T A 6: 130,364,261 I250F probably benign Het
Klra4 T A 6: 130,062,022 T136S probably benign Het
Mcrs1 A T 15: 99,243,385 I399N probably damaging Het
Neo1 T C 9: 58,907,085 E866G possibly damaging Het
Notch3 T C 17: 32,144,471 D1206G probably damaging Het
Olfr1427 A C 19: 12,099,405 V78G probably benign Het
Olfr1443 A C 19: 12,680,749 I214L probably benign Het
Olfr290 T A 7: 84,916,382 V201E probably damaging Het
Olfr299 T A 7: 86,466,272 I287N probably damaging Het
Olfr479 A G 7: 108,054,981 probably benign Het
Olfr800 A G 10: 129,660,126 T107A probably benign Het
Pnkd A G 1: 74,351,557 N336D probably damaging Het
Prag1 T C 8: 36,103,934 V557A probably benign Het
Ptgfr A C 3: 151,835,686 S62A probably benign Het
Smc2 A G 4: 52,450,842 Y220C probably damaging Het
Sufu G A 19: 46,450,943 E246K probably damaging Het
Sult4a1 T A 15: 84,086,616 Y196F possibly damaging Het
Trim15 G A 17: 36,865,083 R191W probably damaging Het
Ttn A G 2: 76,942,975 V2361A possibly damaging Het
Usp16 T C 16: 87,466,276 V122A possibly damaging Het
Vmn1r122 T A 7: 21,134,111 K6N probably benign Het
Vmn1r34 G A 6: 66,636,915 Q280* probably null Het
Vmn2r45 T A 7: 8,481,333 H491L possibly damaging Het
Wdpcp T C 11: 21,711,949 L407P probably damaging Het
Zfp157 T C 5: 138,447,578 I65T probably benign Het
Other mutations in Sult2a1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00896:Sult2a1 APN 7 13832640 missense probably benign 0.02
IGL00990:Sult2a1 APN 7 13804036 missense probably benign
IGL02558:Sult2a1 APN 7 13832595 missense probably benign 0.03
IGL03033:Sult2a1 APN 7 13832710 splice site probably benign
IGL03199:Sult2a1 APN 7 13832660 missense probably damaging 1.00
R1633:Sult2a1 UTSW 7 13801426 missense probably benign 0.01
R1903:Sult2a1 UTSW 7 13835975 missense possibly damaging 0.94
R2295:Sult2a1 UTSW 7 13835959 critical splice donor site probably null
R4207:Sult2a1 UTSW 7 13801547 missense probably benign 0.00
R5444:Sult2a1 UTSW 7 13836019 missense possibly damaging 0.80
R6233:Sult2a1 UTSW 7 13832675 missense probably damaging 1.00
R6317:Sult2a1 UTSW 7 13836020 missense probably benign 0.00
R6853:Sult2a1 UTSW 7 13801487 missense possibly damaging 0.50
R7098:Sult2a1 UTSW 7 13816053 splice site probably null
Z1088:Sult2a1 UTSW 7 13801414 missense probably benign
Z1088:Sult2a1 UTSW 7 13801435 missense probably benign 0.00
Z1088:Sult2a1 UTSW 7 13804036 missense probably benign
Z1176:Sult2a1 UTSW 7 13801414 missense probably benign
Z1176:Sult2a1 UTSW 7 13801435 missense probably benign 0.00
Z1176:Sult2a1 UTSW 7 13804036 missense probably benign
Z1176:Sult2a1 UTSW 7 13835967 missense probably damaging 1.00
Z1177:Sult2a1 UTSW 7 13796363 frame shift probably null
Z1177:Sult2a1 UTSW 7 13801414 missense probably benign
Z1177:Sult2a1 UTSW 7 13801435 missense probably benign 0.00
Z1177:Sult2a1 UTSW 7 13804036 missense probably benign
Posted On2013-10-07