Incidental Mutation 'IGL01322:Vmn1r122'
ID74075
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r122
Ensembl Gene ENSMUSG00000094001
Gene Namevomeronasal 1 receptor 122
SynonymsGm5729
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL01322
Quality Score
Status
Chromosome7
Chromosomal Location21133211-21134128 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 21134111 bp
ZygosityHeterozygous
Amino Acid Change Lysine to Asparagine at position 6 (K6N)
Ref Sequence ENSEMBL: ENSMUSP00000131706 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000164409]
Predicted Effect probably benign
Transcript: ENSMUST00000164409
AA Change: K6N

PolyPhen 2 Score 0.070 (Sensitivity: 0.94; Specificity: 0.84)
SMART Domains Protein: ENSMUSP00000131706
Gene: ENSMUSG00000094001
AA Change: K6N

DomainStartEndE-ValueType
Pfam:TAS2R 8 297 1.2e-17 PFAM
Pfam:7tm_1 31 288 1.6e-6 PFAM
Pfam:V1R 41 296 2.5e-18 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca16 T A 7: 120,439,199 L368Q probably damaging Het
Abca2 T A 2: 25,446,782 probably null Het
Ano7 T A 1: 93,395,508 V497D probably benign Het
B4gat1 T C 19: 5,040,009 Y345H probably damaging Het
Bckdha T A 7: 25,658,707 R12W possibly damaging Het
Bcl7c T A 7: 127,707,436 N93Y probably damaging Het
Cc2d2a C A 5: 43,689,003 T368K probably benign Het
Chek1 G A 9: 36,718,421 Q210* probably null Het
Chrdl2 A G 7: 100,017,041 Y56C probably damaging Het
Cspg4 T A 9: 56,898,588 F2228I probably damaging Het
Dnah7a T C 1: 53,434,046 M3474V probably benign Het
Dph7 T C 2: 24,965,617 S143P possibly damaging Het
Ehbp1 T A 11: 22,089,636 K821N probably damaging Het
Eomes T C 9: 118,484,830 S648P probably benign Het
Fam20a A G 11: 109,682,912 V215A probably damaging Het
Fer1l4 T A 2: 156,020,339 probably null Het
Frem2 A G 3: 53,541,038 V2319A probably benign Het
Gtf3c4 T C 2: 28,833,572 D575G probably benign Het
Ifit1bl2 A G 19: 34,619,004 V404A probably benign Het
Kcnf1 T C 12: 17,175,348 M291V probably benign Het
Klra1 T A 6: 130,364,261 I250F probably benign Het
Klra4 T A 6: 130,062,022 T136S probably benign Het
Mcrs1 A T 15: 99,243,385 I399N probably damaging Het
Neo1 T C 9: 58,907,085 E866G possibly damaging Het
Notch3 T C 17: 32,144,471 D1206G probably damaging Het
Olfr1427 A C 19: 12,099,405 V78G probably benign Het
Olfr1443 A C 19: 12,680,749 I214L probably benign Het
Olfr290 T A 7: 84,916,382 V201E probably damaging Het
Olfr299 T A 7: 86,466,272 I287N probably damaging Het
Olfr479 A G 7: 108,054,981 probably benign Het
Olfr800 A G 10: 129,660,126 T107A probably benign Het
Pnkd A G 1: 74,351,557 N336D probably damaging Het
Prag1 T C 8: 36,103,934 V557A probably benign Het
Ptgfr A C 3: 151,835,686 S62A probably benign Het
Smc2 A G 4: 52,450,842 Y220C probably damaging Het
Sufu G A 19: 46,450,943 E246K probably damaging Het
Sult2a1 T A 7: 13,832,679 R124* probably null Het
Sult4a1 T A 15: 84,086,616 Y196F possibly damaging Het
Trim15 G A 17: 36,865,083 R191W probably damaging Het
Ttn A G 2: 76,942,975 V2361A possibly damaging Het
Usp16 T C 16: 87,466,276 V122A possibly damaging Het
Vmn1r34 G A 6: 66,636,915 Q280* probably null Het
Vmn2r45 T A 7: 8,481,333 H491L possibly damaging Het
Wdpcp T C 11: 21,711,949 L407P probably damaging Het
Zfp157 T C 5: 138,447,578 I65T probably benign Het
Other mutations in Vmn1r122
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01015:Vmn1r122 APN 7 21133836 missense probably damaging 1.00
IGL01397:Vmn1r122 APN 7 21133782 missense possibly damaging 0.91
IGL02894:Vmn1r122 APN 7 21133724 missense probably benign
R1837:Vmn1r122 UTSW 7 21133366 missense probably benign 0.34
R3040:Vmn1r122 UTSW 7 21133446 missense probably benign
R4111:Vmn1r122 UTSW 7 21133513 missense probably damaging 1.00
R4868:Vmn1r122 UTSW 7 21133302 missense probably benign 0.01
R5239:Vmn1r122 UTSW 7 21134098 missense possibly damaging 0.69
R6851:Vmn1r122 UTSW 7 21133920 missense probably benign
R7010:Vmn1r122 UTSW 7 21133971 missense probably damaging 0.97
R7184:Vmn1r122 UTSW 7 21133895 missense probably benign 0.14
R7922:Vmn1r122 UTSW 7 21133662 missense possibly damaging 0.89
Posted On2013-10-07