Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01323:Tmem201'

74147

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tmem201

Ensembl Gene

ENSMUSG00000044700

Gene Name

transmembrane protein 201

Synonyms

Samp1, D4Ertd429e

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.433) question?

Stock #

IGL01323

Quality Score

Status

Chromosome

Chromosomal Location

149799832-149822501 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

G to A at 149804045 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000101312 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000054459] [ENSMUST00000105687]

AlphaFold

A2A8U2

Predicted Effect

probably benign
Transcript: ENSMUST00000054459

SMART Domains

Protein: ENSMUSP00000050481
Gene: ENSMUSG00000044700

Domain	Start	End	E-Value	Type
transmembrane domain	13	35	N/A	INTRINSIC
Pfam:Ima1_N	46	171	2.6e-43	PFAM
Pfam:DUF2448	191	392	4.4e-102	PFAM
low complexity region	433	455	N/A	INTRINSIC
low complexity region	486	521	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000105687

SMART Domains

Protein: ENSMUSP00000101312
Gene: ENSMUSG00000044700

Domain	Start	End	E-Value	Type
transmembrane domain	13	35	N/A	INTRINSIC
Pfam:Ima1_N	46	171	2.4e-39	PFAM
Pfam:DUF2448	191	389	3.1e-96	PFAM
low complexity region	433	455	N/A	INTRINSIC
low complexity region	486	521	N/A	INTRINSIC
transmembrane domain	638	660	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 43 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Arfgef2	A	G	2: 166,713,415 (GRCm39)	D1272G	probably damaging	Het
Ascl2	A	G	7: 142,522,125 (GRCm39)	S108P	probably benign	Het
B3gat1	T	C	9: 26,667,206 (GRCm39)	V146A	possibly damaging	Het
Barhl1	C	T	2: 28,805,558 (GRCm39)	S45N	probably benign	Het
Birc6	C	T	17: 74,929,920 (GRCm39)	A2370V	probably damaging	Het
C1qtnf7	A	G	5: 43,766,602 (GRCm39)	D67G	possibly damaging	Het
Cand2	A	G	6: 115,762,086 (GRCm39)	T171A	probably benign	Het
Ccdc77	T	C	6: 120,311,757 (GRCm39)	Q247R	probably benign	Het
Cenpp	A	T	13: 49,801,118 (GRCm39)	V100D	probably damaging	Het
Cep135	A	G	5: 76,739,612 (GRCm39)	T3A	probably benign	Het
Eef2k	T	C	7: 120,484,038 (GRCm39)		probably benign	Het
Fga	T	C	3: 82,937,518 (GRCm39)	S132P	probably damaging	Het
Gpr6	T	A	10: 40,947,555 (GRCm39)	N9I	possibly damaging	Het
Gvin2	A	G	7: 105,546,009 (GRCm39)	S2348P	possibly damaging	Het
Hacd3	A	G	9: 64,905,587 (GRCm39)	F184L	probably damaging	Het
Heatr1	T	C	13: 12,413,819 (GRCm39)	I132T	possibly damaging	Het
Igfbp7	A	G	5: 77,499,884 (GRCm39)		probably benign	Het
Ighv8-6	T	C	12: 115,129,477 (GRCm39)	D93G	possibly damaging	Het
Izumo3	A	G	4: 92,034,627 (GRCm39)		probably benign	Het
Jade2	T	C	11: 51,716,165 (GRCm39)	T347A	possibly damaging	Het
Kif18a	A	G	2: 109,128,787 (GRCm39)	T419A	probably benign	Het
Krt34	A	G	11: 99,929,606 (GRCm39)	S267P	possibly damaging	Het
Krt4	T	G	15: 101,828,716 (GRCm39)	K383Q	probably damaging	Het
Lgals7	G	T	7: 28,564,989 (GRCm39)	E42D	probably benign	Het
Morc2b	A	G	17: 33,356,293 (GRCm39)	V493A	possibly damaging	Het
Mtif2	T	A	11: 29,491,447 (GRCm39)	S557R	probably damaging	Het
Nup43	T	A	10: 7,545,320 (GRCm39)	F83I	probably benign	Het
Oosp2	A	G	19: 11,624,825 (GRCm39)	L155S	probably damaging	Het
Or1o1	G	T	17: 37,717,031 (GRCm39)	M197I	probably benign	Het
Plxnd1	T	A	6: 115,943,760 (GRCm39)	T1180S	possibly damaging	Het
Prpf39	T	A	12: 65,089,498 (GRCm39)	F79I	possibly damaging	Het
Prph	G	A	15: 98,956,517 (GRCm39)	S465N	possibly damaging	Het
Purg	A	T	8: 33,876,631 (GRCm39)	I90L	probably damaging	Het
Pxdn	C	A	12: 30,037,136 (GRCm39)	Q305K	probably benign	Het
R3hdm1	G	A	1: 128,144,280 (GRCm39)	S816N	probably benign	Het
Src	G	A	2: 157,311,423 (GRCm39)	G461R	probably damaging	Het
Tnfrsf22	G	A	7: 143,197,111 (GRCm39)	P76L	probably damaging	Het
Triml1	T	C	8: 43,591,600 (GRCm39)		probably null	Het
Upp1	A	G	11: 9,086,100 (GRCm39)	*312W	probably null	Het
Wdfy3	G	T	5: 102,042,930 (GRCm39)	S1940R	probably damaging	Het
Xpc	T	C	6: 91,469,335 (GRCm39)	Y804C	probably damaging	Het
Xrn2	C	T	2: 146,876,767 (GRCm39)		probably benign	Het
Zfp106	A	T	2: 120,354,945 (GRCm39)	D1275E	possibly damaging	Het

Other mutations in Tmem201

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R0508:Tmem201	UTSW	4	149,816,343 (GRCm39)	missense	probably damaging	1.00
R0717:Tmem201	UTSW	4	149,803,267 (GRCm39)	missense	probably damaging	1.00
R1660:Tmem201	UTSW	4	149,804,032 (GRCm39)	missense	probably damaging	1.00
R2138:Tmem201	UTSW	4	149,802,537 (GRCm39)	missense	probably damaging	1.00
R2971:Tmem201	UTSW	4	149,806,902 (GRCm39)	splice site	probably benign
R4430:Tmem201	UTSW	4	149,815,596 (GRCm39)	missense	probably benign	0.03
R4704:Tmem201	UTSW	4	149,811,774 (GRCm39)	missense	possibly damaging	0.77
R4876:Tmem201	UTSW	4	149,806,727 (GRCm39)	missense	probably damaging	1.00
R4966:Tmem201	UTSW	4	149,803,144 (GRCm39)	missense	probably benign
R4991:Tmem201	UTSW	4	149,812,612 (GRCm39)	missense	possibly damaging	0.95
R5518:Tmem201	UTSW	4	149,802,534 (GRCm39)	missense	probably benign
R5818:Tmem201	UTSW	4	149,811,849 (GRCm39)	missense	probably benign	0.33
R7399:Tmem201	UTSW	4	149,815,554 (GRCm39)	missense	possibly damaging	0.95
R8142:Tmem201	UTSW	4	149,803,114 (GRCm39)	missense	probably benign
R8170:Tmem201	UTSW	4	149,803,177 (GRCm39)	missense	probably benign	0.29
R8294:Tmem201	UTSW	4	149,815,554 (GRCm39)	missense	possibly damaging	0.95
R8513:Tmem201	UTSW	4	149,812,380 (GRCm39)	missense	probably damaging	0.99
R8808:Tmem201	UTSW	4	149,814,138 (GRCm39)	missense	possibly damaging	0.79
R9026:Tmem201	UTSW	4	149,812,627 (GRCm39)	missense	probably benign	0.08
X0064:Tmem201	UTSW	4	149,802,528 (GRCm39)	missense	possibly damaging	0.75

Posted On

2013-10-07