Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01326:Gm9631'

74248

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm9631

Ensembl Gene

Gene Name

predicted gene 9631

Synonyms

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL01326

Quality Score

Status

Chromosome

Chromosomal Location

121797437-121816154 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 121836454 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glutamic Acid at position 28 (D28E)

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000130783
AA Change: D28E

PolyPhen 2 Score 0.830 (Sensitivity: 0.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000118097
Gene: ENSMUSG00000078564
AA Change: D28E

Domain	Start	End	E-Value	Type
signal peptide	1	20	N/A	INTRINSIC
KRAB	30	86	3.16e-12	SMART
ZnF_C2H2	157	177	1.69e2	SMART
ZnF_C2H2	185	207	1.36e-2	SMART
ZnF_C2H2	213	235	6.78e-3	SMART
ZnF_C2H2	241	263	2.79e-4	SMART
ZnF_C2H2	269	291	1.2e-3	SMART
ZnF_C2H2	297	319	9.88e-5	SMART
ZnF_C2H2	325	347	7.78e-3	SMART
ZnF_C2H2	353	375	1.12e-3	SMART
ZnF_C2H2	381	403	7.78e-3	SMART
ZnF_C2H2	409	431	1.5e-4	SMART
ZnF_C2H2	437	459	9.08e-4	SMART
ZnF_C2H2	465	487	1.04e-3	SMART
ZnF_C2H2	493	515	2.27e-4	SMART
ZnF_C2H2	521	543	4.17e-3	SMART
ZnF_C2H2	550	572	1.1e-2	SMART
ZnF_C2H2	578	600	3.95e-4	SMART
ZnF_C2H2	606	628	7.9e-4	SMART
ZnF_C2H2	634	656	9.73e-4	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 47 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adh1	G	A	3: 137,992,672 (GRCm39)	V263M	probably damaging	Het
Akap13	T	A	7: 75,375,096 (GRCm39)	H1909Q	probably benign	Het
Atg2b	C	T	12: 105,588,403 (GRCm39)	A1936T	probably damaging	Het
Atp8b3	G	T	10: 80,360,210 (GRCm39)	L954M	probably damaging	Het
C8a	T	C	4: 104,713,617 (GRCm39)	Y171C	probably damaging	Het
Cd6	A	G	19: 10,768,466 (GRCm39)	S508P	probably benign	Het
Cdk4	A	G	10: 126,900,492 (GRCm39)	D86G	possibly damaging	Het
Cdr2l	G	T	11: 115,281,796 (GRCm39)	R100S	probably benign	Het
Cndp1	T	A	18: 84,640,357 (GRCm39)	T283S	probably benign	Het
Cr2	T	C	1: 194,823,529 (GRCm39)	Y1023C	probably null	Het
Csmd3	A	G	15: 47,713,181 (GRCm39)	F1494L	probably benign	Het
Eeig2	A	G	3: 108,887,101 (GRCm39)	V299A	possibly damaging	Het
Eng	G	T	2: 32,562,394 (GRCm39)	G231W	probably benign	Het
Erp44	A	G	4: 48,218,126 (GRCm39)	V181A	probably benign	Het
Fkbp15	A	G	4: 62,241,487 (GRCm39)	S553P	probably damaging	Het
Glg1	A	G	8: 111,909,205 (GRCm39)	V495A	probably damaging	Het
Gnptab	G	T	10: 88,268,927 (GRCm39)	L543F	probably damaging	Het
H4c3	A	T	13: 23,882,353 (GRCm39)	I27N	probably damaging	Het
Khdrbs2	T	G	1: 32,696,558 (GRCm39)	L329R	possibly damaging	Het
Kidins220	C	A	12: 25,088,498 (GRCm39)	H1080Q	probably damaging	Het
Maml1	G	A	11: 50,156,715 (GRCm39)	P487S	probably benign	Het
Me1	C	T	9: 86,480,771 (GRCm39)		probably null	Het
Morc2a	C	T	11: 3,631,775 (GRCm39)	R569C	probably benign	Het
Mrc1	A	G	2: 14,271,335 (GRCm39)	Q413R	probably damaging	Het
Mrgprx1	A	T	7: 47,671,517 (GRCm39)	C77S	probably benign	Het
Mtarc2	T	C	1: 184,566,048 (GRCm39)		probably benign	Het
Myo1d	A	T	11: 80,575,147 (GRCm39)		probably benign	Het
Nr4a1	T	G	15: 101,171,940 (GRCm39)	L538R	probably damaging	Het
Olfm1	T	C	2: 28,119,564 (GRCm39)	Y385H	probably damaging	Het
Or4a39	A	T	2: 89,236,675 (GRCm39)	F249L	possibly damaging	Het
Or5m9	A	G	2: 85,877,627 (GRCm39)	E267G	probably damaging	Het
Pkd1	T	A	17: 24,795,148 (GRCm39)	Y2278*	probably null	Het
Plcg2	T	C	8: 118,300,738 (GRCm39)		probably benign	Het
Prkdc	G	T	16: 15,647,556 (GRCm39)	C3660F	probably benign	Het
Ptpn11	T	C	5: 121,281,199 (GRCm39)	D493G	probably damaging	Het
Rad23b	T	A	4: 55,383,601 (GRCm39)	F278I	possibly damaging	Het
Saxo2	T	C	7: 82,297,613 (GRCm39)	I9V	probably benign	Het
Scn7a	T	C	2: 66,582,604 (GRCm39)	I98V	probably benign	Het
Serac1	T	A	17: 6,124,528 (GRCm39)		probably benign	Het
Simc1	T	C	13: 54,672,473 (GRCm39)	C274R	probably benign	Het
Sirt3	A	G	7: 140,444,006 (GRCm39)		probably benign	Het
Tctn3	A	G	19: 40,585,880 (GRCm39)	L555P	probably damaging	Het
Ttc14	A	G	3: 33,855,507 (GRCm39)	I151V	probably benign	Het
Ush2a	T	A	1: 187,995,518 (GRCm39)	Y96*	probably null	Het
Usp42	T	C	5: 143,706,970 (GRCm39)	T270A	possibly damaging	Het
Vmn1r31	A	G	6: 58,449,784 (GRCm39)	I27T	probably benign	Het
Vmn2r93	G	A	17: 18,536,906 (GRCm39)	A530T	possibly damaging	Het

Other mutations in Gm9631

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02411:Gm9631	APN	11	121,834,478 (GRCm39)
IGL02417:Gm9631	APN	11	121,834,478 (GRCm39)
IGL02419:Gm9631	APN	11	121,834,478 (GRCm39)
IGL02420:Gm9631	APN	11	121,834,478 (GRCm39)
R0646:Gm9631	UTSW	11	121,836,455 (GRCm39)	missense	probably damaging	0.99
R0715:Gm9631	UTSW	11	121,833,328 (GRCm39)	missense	probably damaging	1.00
R3978:Gm9631	UTSW	11	121,834,394 (GRCm39)	missense	possibly damaging	0.46

Posted On

2013-10-07