Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01326:Myo1d'

74291

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Myo1d

Ensembl Gene

ENSMUSG00000035441

Gene Name

myosin ID

Synonyms

D11Ertd9e, 9930104H07Rik

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL01326

Quality Score

Status

Chromosome

Chromosomal Location

80372952-80670851 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to T at 80575147 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000066948 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000041065] [ENSMUST00000070997]

AlphaFold

Q5SYD0

Predicted Effect

probably benign
Transcript: ENSMUST00000041065

SMART Domains

Protein: ENSMUSP00000037819
Gene: ENSMUSG00000035441

Domain	Start	End	E-Value	Type
MYSc	3	696	N/A	SMART
IQ	697	719	1.46e-3	SMART
Pfam:Myosin_TH1	803	1006	4.1e-49	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000070997

SMART Domains

Protein: ENSMUSP00000066948
Gene: ENSMUSG00000035441

Domain	Start	End	E-Value	Type
MYSc	3	696	N/A	SMART
IQ	697	719	1.46e-3	SMART
Pfam:Myosin_TH1	802	913	1.8e-26	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000125944

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 47 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adh1	G	A	3: 137,992,672 (GRCm39)	V263M	probably damaging	Het
Akap13	T	A	7: 75,375,096 (GRCm39)	H1909Q	probably benign	Het
Atg2b	C	T	12: 105,588,403 (GRCm39)	A1936T	probably damaging	Het
Atp8b3	G	T	10: 80,360,210 (GRCm39)	L954M	probably damaging	Het
C8a	T	C	4: 104,713,617 (GRCm39)	Y171C	probably damaging	Het
Cd6	A	G	19: 10,768,466 (GRCm39)	S508P	probably benign	Het
Cdk4	A	G	10: 126,900,492 (GRCm39)	D86G	possibly damaging	Het
Cdr2l	G	T	11: 115,281,796 (GRCm39)	R100S	probably benign	Het
Cndp1	T	A	18: 84,640,357 (GRCm39)	T283S	probably benign	Het
Cr2	T	C	1: 194,823,529 (GRCm39)	Y1023C	probably null	Het
Csmd3	A	G	15: 47,713,181 (GRCm39)	F1494L	probably benign	Het
Eeig2	A	G	3: 108,887,101 (GRCm39)	V299A	possibly damaging	Het
Eng	G	T	2: 32,562,394 (GRCm39)	G231W	probably benign	Het
Erp44	A	G	4: 48,218,126 (GRCm39)	V181A	probably benign	Het
Fkbp15	A	G	4: 62,241,487 (GRCm39)	S553P	probably damaging	Het
Glg1	A	G	8: 111,909,205 (GRCm39)	V495A	probably damaging	Het
Gm9631	A	T	11: 121,836,454 (GRCm39)	D28E	possibly damaging	Het
Gnptab	G	T	10: 88,268,927 (GRCm39)	L543F	probably damaging	Het
H4c3	A	T	13: 23,882,353 (GRCm39)	I27N	probably damaging	Het
Khdrbs2	T	G	1: 32,696,558 (GRCm39)	L329R	possibly damaging	Het
Kidins220	C	A	12: 25,088,498 (GRCm39)	H1080Q	probably damaging	Het
Maml1	G	A	11: 50,156,715 (GRCm39)	P487S	probably benign	Het
Me1	C	T	9: 86,480,771 (GRCm39)		probably null	Het
Morc2a	C	T	11: 3,631,775 (GRCm39)	R569C	probably benign	Het
Mrc1	A	G	2: 14,271,335 (GRCm39)	Q413R	probably damaging	Het
Mrgprx1	A	T	7: 47,671,517 (GRCm39)	C77S	probably benign	Het
Mtarc2	T	C	1: 184,566,048 (GRCm39)		probably benign	Het
Nr4a1	T	G	15: 101,171,940 (GRCm39)	L538R	probably damaging	Het
Olfm1	T	C	2: 28,119,564 (GRCm39)	Y385H	probably damaging	Het
Or4a39	A	T	2: 89,236,675 (GRCm39)	F249L	possibly damaging	Het
Or5m9	A	G	2: 85,877,627 (GRCm39)	E267G	probably damaging	Het
Pkd1	T	A	17: 24,795,148 (GRCm39)	Y2278*	probably null	Het
Plcg2	T	C	8: 118,300,738 (GRCm39)		probably benign	Het
Prkdc	G	T	16: 15,647,556 (GRCm39)	C3660F	probably benign	Het
Ptpn11	T	C	5: 121,281,199 (GRCm39)	D493G	probably damaging	Het
Rad23b	T	A	4: 55,383,601 (GRCm39)	F278I	possibly damaging	Het
Saxo2	T	C	7: 82,297,613 (GRCm39)	I9V	probably benign	Het
Scn7a	T	C	2: 66,582,604 (GRCm39)	I98V	probably benign	Het
Serac1	T	A	17: 6,124,528 (GRCm39)		probably benign	Het
Simc1	T	C	13: 54,672,473 (GRCm39)	C274R	probably benign	Het
Sirt3	A	G	7: 140,444,006 (GRCm39)		probably benign	Het
Tctn3	A	G	19: 40,585,880 (GRCm39)	L555P	probably damaging	Het
Ttc14	A	G	3: 33,855,507 (GRCm39)	I151V	probably benign	Het
Ush2a	T	A	1: 187,995,518 (GRCm39)	Y96*	probably null	Het
Usp42	T	C	5: 143,706,970 (GRCm39)	T270A	possibly damaging	Het
Vmn1r31	A	G	6: 58,449,784 (GRCm39)	I27T	probably benign	Het
Vmn2r93	G	A	17: 18,536,906 (GRCm39)	A530T	possibly damaging	Het

Other mutations in Myo1d

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00432:Myo1d	APN	11	80,492,566 (GRCm39)	missense	probably benign
IGL01087:Myo1d	APN	11	80,573,261 (GRCm39)	missense	probably damaging	1.00
IGL01431:Myo1d	APN	11	80,565,665 (GRCm39)	missense	probably damaging	1.00
IGL01595:Myo1d	APN	11	80,566,936 (GRCm39)	missense	probably benign	0.00
IGL01811:Myo1d	APN	11	80,583,823 (GRCm39)	missense	probably damaging	0.96
IGL02301:Myo1d	APN	11	80,567,679 (GRCm39)	missense	probably benign	0.23
IGL02388:Myo1d	APN	11	80,528,823 (GRCm39)	nonsense	probably null
IGL02485:Myo1d	APN	11	80,557,407 (GRCm39)	missense	probably damaging	1.00
IGL03017:Myo1d	APN	11	80,492,452 (GRCm39)	missense	probably benign	0.26
horton	UTSW	11	80,565,534 (GRCm39)	missense	probably damaging	1.00
multifaceted	UTSW	11	80,583,898 (GRCm39)	missense	probably damaging	1.00
whisper	UTSW	11	80,375,158 (GRCm39)	missense	probably damaging	0.99
whisper2	UTSW	11	80,557,404 (GRCm39)	missense	probably damaging	1.00
whisper3	UTSW	11	80,448,347 (GRCm39)	missense	probably damaging	1.00
R0069:Myo1d	UTSW	11	80,528,779 (GRCm39)	missense	probably damaging	1.00
R0069:Myo1d	UTSW	11	80,528,779 (GRCm39)	missense	probably damaging	1.00
R0081:Myo1d	UTSW	11	80,448,349 (GRCm39)	missense	probably benign	0.00
R0096:Myo1d	UTSW	11	80,375,158 (GRCm39)	missense	probably damaging	0.99
R0096:Myo1d	UTSW	11	80,375,158 (GRCm39)	missense	probably damaging	0.99
R0244:Myo1d	UTSW	11	80,565,534 (GRCm39)	missense	probably damaging	1.00
R0711:Myo1d	UTSW	11	80,375,158 (GRCm39)	missense	probably damaging	0.99
R0746:Myo1d	UTSW	11	80,477,705 (GRCm39)	missense	possibly damaging	0.94
R1084:Myo1d	UTSW	11	80,575,221 (GRCm39)	missense	probably damaging	1.00
R1514:Myo1d	UTSW	11	80,576,734 (GRCm39)	missense	probably damaging	0.97
R1676:Myo1d	UTSW	11	80,575,247 (GRCm39)	missense	probably damaging	1.00
R1862:Myo1d	UTSW	11	80,553,874 (GRCm39)	missense	probably damaging	1.00
R2497:Myo1d	UTSW	11	80,565,647 (GRCm39)	missense	probably damaging	1.00
R2512:Myo1d	UTSW	11	80,670,543 (GRCm39)	missense	probably benign	0.00
R3425:Myo1d	UTSW	11	80,492,464 (GRCm39)	missense	probably benign
R3429:Myo1d	UTSW	11	80,573,236 (GRCm39)	missense	probably damaging	1.00
R3917:Myo1d	UTSW	11	80,557,404 (GRCm39)	missense	probably damaging	1.00
R3928:Myo1d	UTSW	11	80,375,087 (GRCm39)	missense	probably benign	0.09
R4706:Myo1d	UTSW	11	80,557,467 (GRCm39)	missense	probably damaging	0.96
R4723:Myo1d	UTSW	11	80,670,667 (GRCm39)	utr 5 prime	probably benign
R4924:Myo1d	UTSW	11	80,565,504 (GRCm39)	missense	probably damaging	1.00
R5042:Myo1d	UTSW	11	80,448,347 (GRCm39)	missense	probably damaging	1.00
R5320:Myo1d	UTSW	11	80,575,149 (GRCm39)	critical splice donor site	probably null
R5481:Myo1d	UTSW	11	80,553,921 (GRCm39)	missense	possibly damaging	0.79
R6214:Myo1d	UTSW	11	80,670,617 (GRCm39)	start codon destroyed	probably null	0.98
R6235:Myo1d	UTSW	11	80,583,770 (GRCm39)	missense	probably benign	0.23
R6282:Myo1d	UTSW	11	80,448,338 (GRCm39)	missense	probably damaging	0.99
R6468:Myo1d	UTSW	11	80,448,300 (GRCm39)	missense	probably benign	0.00
R6668:Myo1d	UTSW	11	80,474,701 (GRCm39)	intron	probably benign
R6954:Myo1d	UTSW	11	80,565,783 (GRCm39)	missense	probably benign	0.21
R7077:Myo1d	UTSW	11	80,565,460 (GRCm39)	missense	probably damaging	1.00
R7078:Myo1d	UTSW	11	80,565,460 (GRCm39)	missense	probably damaging	1.00
R7080:Myo1d	UTSW	11	80,565,460 (GRCm39)	missense	probably damaging	1.00
R7172:Myo1d	UTSW	11	80,483,621 (GRCm39)	missense	probably benign	0.16
R7276:Myo1d	UTSW	11	80,583,898 (GRCm39)	missense	probably damaging	1.00
R7467:Myo1d	UTSW	11	80,477,743 (GRCm39)	missense	probably damaging	1.00
R7650:Myo1d	UTSW	11	80,492,510 (GRCm39)	missense	probably benign
R7678:Myo1d	UTSW	11	80,567,719 (GRCm39)	missense	possibly damaging	0.80
R7859:Myo1d	UTSW	11	80,575,203 (GRCm39)	missense	probably damaging	1.00
R8324:Myo1d	UTSW	11	80,448,347 (GRCm39)	missense	probably damaging	1.00
R8329:Myo1d	UTSW	11	80,528,900 (GRCm39)	missense	probably benign	0.21
R8474:Myo1d	UTSW	11	80,561,745 (GRCm39)	missense	possibly damaging	0.93
R8799:Myo1d	UTSW	11	80,575,205 (GRCm39)	missense	probably damaging	1.00
R8810:Myo1d	UTSW	11	80,567,758 (GRCm39)	missense	probably benign	0.30
R8810:Myo1d	UTSW	11	80,565,758 (GRCm39)	missense	probably damaging	1.00
R8823:Myo1d	UTSW	11	80,492,571 (GRCm39)	missense	possibly damaging	0.91
R9221:Myo1d	UTSW	11	80,565,744 (GRCm39)	missense	probably damaging	1.00
R9494:Myo1d	UTSW	11	80,375,093 (GRCm39)	missense	probably benign	0.02
R9625:Myo1d	UTSW	11	80,448,296 (GRCm39)	missense	possibly damaging	0.95
R9626:Myo1d	UTSW	11	80,448,296 (GRCm39)	missense	possibly damaging	0.95
R9628:Myo1d	UTSW	11	80,448,296 (GRCm39)	missense	possibly damaging	0.95
Z1088:Myo1d	UTSW	11	80,565,724 (GRCm39)	missense	probably benign	0.01

Posted On

2013-10-07