Incidental Mutation 'IGL01327:Gm3696'
ID74299
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm3696
Ensembl Gene ENSMUSG00000092167
Gene Namepredicted gene 3696
SynonymsGm5794
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL01327
Quality Score
Status
Chromosome14
Chromosomal Location7083208-7100621 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 7090701 bp
ZygosityHeterozygous
Amino Acid Change Tryptophan to Arginine at position 38 (W38R)
Ref Sequence ENSEMBL: ENSMUSP00000137098 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000167923] [ENSMUST00000179898]
Predicted Effect probably benign
Transcript: ENSMUST00000167923
AA Change: W38R

PolyPhen 2 Score 0.237 (Sensitivity: 0.91; Specificity: 0.88)
SMART Domains Protein: ENSMUSP00000132868
Gene: ENSMUSG00000092167
AA Change: W38R

DomainStartEndE-ValueType
Pfam:Takusan 48 128 1.3e-22 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000179898
AA Change: W38R

PolyPhen 2 Score 0.237 (Sensitivity: 0.91; Specificity: 0.88)
SMART Domains Protein: ENSMUSP00000137098
Gene: ENSMUSG00000092167
AA Change: W38R

DomainStartEndE-ValueType
Pfam:Takusan 46 129 1e-31 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 57 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2510039O18Rik T A 4: 147,945,064 V497E probably damaging Het
4930563D23Rik T C 16: 92,320,773 Y209C probably benign Het
Adcy7 T G 8: 88,318,790 probably benign Het
Aldh1a2 T A 9: 71,285,966 F486I possibly damaging Het
Alox12 T A 11: 70,254,549 H66L probably benign Het
Apoh T G 11: 108,397,361 Y102D probably damaging Het
Arl9 T C 5: 77,006,554 V43A possibly damaging Het
Atf6 A G 1: 170,788,606 probably null Het
Atp4a T A 7: 30,713,250 I127N possibly damaging Het
AY358078 T A 14: 51,805,709 probably benign Het
Baat T G 4: 49,490,338 K249Q probably damaging Het
Brat1 C T 5: 140,718,208 Q739* probably null Het
C8g A G 2: 25,499,077 F165L probably damaging Het
Cel T G 2: 28,557,955 D353A possibly damaging Het
Col6a1 G T 10: 76,710,979 T803K unknown Het
Cpxm1 A G 2: 130,396,357 L95P probably benign Het
Ctsr A G 13: 61,162,675 probably benign Het
Cyth1 A G 11: 118,193,613 probably null Het
Dync1h1 A T 12: 110,616,692 probably benign Het
Ezh1 C T 11: 101,203,436 C407Y probably damaging Het
Gm9611 T C 14: 42,294,665 T39A possibly damaging Het
Gnpat T A 8: 124,878,633 L287H probably damaging Het
Golm1 G T 13: 59,645,144 N182K possibly damaging Het
Hdac6 T C X: 7,931,774 M899V probably benign Het
Hsf3 T A X: 96,314,972 M272L probably benign Het
Kif19a C T 11: 114,781,799 probably benign Het
Lcn2 T G 2: 32,386,018 Y100S possibly damaging Het
Lrrc8d T A 5: 105,812,265 S180R probably damaging Het
Ly6h A G 15: 75,565,099 probably benign Het
Macf1 T C 4: 123,509,912 N705D probably benign Het
Mst1r C T 9: 107,907,844 P234S probably benign Het
Msto1 T A 3: 88,910,632 probably null Het
Myo5a T A 9: 75,187,538 probably benign Het
Nipa1 T C 7: 55,979,661 I235V probably benign Het
Nlgn3 T C X: 101,318,622 V399A probably benign Het
Olfr1367 A G 13: 21,347,207 N93S probably benign Het
Olfr412 T A 11: 74,364,912 M81K possibly damaging Het
Pih1d1 T C 7: 45,159,975 S289P probably benign Het
Ppl T C 16: 5,087,644 N1596D probably benign Het
Psmb6 T A 11: 70,526,586 S114R possibly damaging Het
Pum1 C A 4: 130,730,543 Q289K probably damaging Het
Shkbp1 T C 7: 27,355,251 I75V probably benign Het
Slc24a3 T A 2: 145,602,558 I284N probably benign Het
Slc44a3 C T 3: 121,527,193 G53D probably damaging Het
Slc9a4 A C 1: 40,629,405 D736A probably benign Het
Stra6 A G 9: 58,152,571 D605G probably benign Het
Tas2r126 T A 6: 42,434,750 H72Q probably benign Het
Tbrg1 C T 9: 37,653,112 R166Q probably benign Het
Thumpd1 C T 7: 119,720,702 G14R probably benign Het
Ticrr C T 7: 79,694,461 T1358I probably benign Het
Tmtc2 A T 10: 105,348,479 N518K probably benign Het
Trpm4 C A 7: 45,315,073 W533C probably damaging Het
Tsen54 T C 11: 115,821,712 Y119H possibly damaging Het
Tulp3 G A 6: 128,327,634 T219M probably damaging Het
Usp19 T C 9: 108,498,961 L1000S possibly damaging Het
Vps16 A T 2: 130,437,696 Y43F probably benign Het
Vsig1 T A X: 140,937,680 V283E possibly damaging Het
Other mutations in Gm3696
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01568:Gm3696 APN 14 7089819 missense probably benign 0.32
IGL01882:Gm3696 APN 14 7087862 missense probably benign
IGL01903:Gm3696 APN 14 7089782 splice site probably benign
R7286:Gm3696 UTSW 14 7089808 missense probably damaging 1.00
R7806:Gm3696 UTSW 14 7087893 missense probably benign 0.16
R7806:Gm3696 UTSW 14 7087894 missense probably benign 0.02
R8080:Gm3696 UTSW 14 7089870 nonsense probably null
Posted On2013-10-07