Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL01329:Ankib1'

74451

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ankib1

Ensembl Gene

ENSMUSG00000040351

Gene Name

ankyrin repeat and IBR domain containing 1

Synonyms

2310061P20Rik, 4631416I11Rik

Accession Numbers

Is this an essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL01329

Quality Score

Status

Chromosome

Chromosomal Location

3690000-3802925 bp(-) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

A to T at 3734194 bp

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000142687 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000043551] [ENSMUST00000200335]

Predicted Effect

probably benign
Transcript: ENSMUST00000043551

SMART Domains

Protein: ENSMUSP00000040946
Gene: ENSMUSG00000040351

Domain	Start	End	E-Value	Type
ANK	45	75	7.08e-1	SMART
ANK	145	174	2.32e-5	SMART
low complexity region	209	219	N/A	INTRINSIC
low complexity region	304	319	N/A	INTRINSIC
RING	334	382	9.73e-2	SMART
IBR	403	479	8.72e-12	SMART
IBR	502	566	2.59e-5	SMART
RING	520	644	2.36e0	SMART
low complexity region	764	773	N/A	INTRINSIC
low complexity region	808	822	N/A	INTRINSIC
UIM	846	865	3.62e-1	SMART
low complexity region	905	917	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000199763

Predicted Effect

probably benign
Transcript: ENSMUST00000200335

SMART Domains

Protein: ENSMUSP00000142687
Gene: ENSMUSG00000040351

Domain	Start	End	E-Value	Type
ANK	45	75	4.5e-3	SMART
ANK	145	174	1.4e-7	SMART
low complexity region	209	219	N/A	INTRINSIC
low complexity region	304	319	N/A	INTRINSIC
RING	334	382	4.6e-4	SMART
IBR	403	479	2.9e-14	SMART
IBR	502	566	8.3e-8	SMART
RING	520	644	1.1e-2	SMART
low complexity region	768	779	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 42 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700028P14Rik	A	G	19: 23,652,736		probably benign	Het
Abcb4	T	C	5: 8,894,166		probably null	Het
Birc3	T	C	9: 7,860,732	Y195C	probably damaging	Het
Cand2	T	C	6: 115,782,794	I142T	probably benign	Het
Cd163l1	T	A	7: 140,224,639		probably null	Het
Cdh15	T	C	8: 122,865,323		probably benign	Het
Ceacam5	G	A	7: 17,745,609	G217D	probably damaging	Het
Cfap54	T	A	10: 93,081,523	H25L	unknown	Het
Col22a1	A	G	15: 71,907,040	V266A	probably benign	Het
D3Ertd751e	A	G	3: 41,748,697	D69G	probably benign	Het
Dnah3	T	C	7: 120,022,941	I1518V	probably damaging	Het
Entpd8	A	G	2: 25,084,346	K381R	probably benign	Het
Fli1	T	A	9: 32,424,101	K345I	probably damaging	Het
G6pd2	T	C	5: 61,809,938	V352A	probably damaging	Het
Gbp11	C	T	5: 105,327,616		probably null	Het
Gm11992	A	G	11: 9,068,383	*292W	probably null	Het
Ifnar2	T	A	16: 91,391,711		probably benign	Het
Impg1	T	C	9: 80,322,829	K661R	probably benign	Het
Inf2	G	T	12: 112,611,856	E651*	probably null	Het
Ints1	A	G	5: 139,767,503		probably benign	Het
Iqcf4	T	C	9: 106,570,633	K26E	probably benign	Het
Map4k3	A	G	17: 80,644,184	V289A	probably benign	Het
Mis18bp1	T	C	12: 65,158,441	K319R	possibly damaging	Het
Nubpl	T	C	12: 52,305,855	V291A	probably damaging	Het
Olfr1085	T	C	2: 86,658,207	N84D	probably benign	Het
Olfr1305	A	G	2: 111,872,950	F302L	probably benign	Het
Olfr726	C	T	14: 50,083,997	R228H	probably benign	Het
Olfr983	A	G	9: 40,092,028	S313P	possibly damaging	Het
Otof	A	G	5: 30,441,379	S29P	probably benign	Het
Pcca	A	G	14: 122,690,133	D436G	possibly damaging	Het
Rasef	T	A	4: 73,727,645	T496S	probably damaging	Het
Saa2	A	G	7: 46,753,472	D49G	probably benign	Het
Scn2a	A	G	2: 65,717,508	I1015V	probably benign	Het
Sim2	T	C	16: 94,106,260	Y154H	possibly damaging	Het
Spag17	A	G	3: 100,095,549	H1863R	probably benign	Het
Supt16	C	T	14: 52,177,032	E438K	probably benign	Het
Svil	A	G	18: 5,064,501	E1111G	probably benign	Het
Trabd2b	T	C	4: 114,409,125	V112A	probably damaging	Het
Vmn1r205	T	C	13: 22,592,103	I276M	probably benign	Het
Vps13d	A	T	4: 145,156,206	I939N	possibly damaging	Het
Zc3h11a	T	C	1: 133,625,862	M515V	probably benign	Het
Zfp457	T	C	13: 67,294,266	T82A	possibly damaging	Het

Other mutations in Ankib1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00226:Ankib1	APN	5	3727573	missense	probably benign	0.20
IGL01372:Ankib1	APN	5	3772594	missense	probably damaging	1.00
IGL01593:Ankib1	APN	5	3732590	missense	probably benign	0.00
IGL01613:Ankib1	APN	5	3713146	nonsense	probably null
IGL01728:Ankib1	APN	5	3701992	splice site	probably benign
IGL01782:Ankib1	APN	5	3727607	missense	probably damaging	1.00
IGL01878:Ankib1	APN	5	3734152	missense	possibly damaging	0.69
IGL02730:Ankib1	APN	5	3702995	missense	probably damaging	1.00
IGL02742:Ankib1	APN	5	3693479	missense	probably benign	0.04
IGL02873:Ankib1	APN	5	3772619	missense	probably damaging	1.00
R0033:Ankib1	UTSW	5	3769588	missense	possibly damaging	0.52
R0242:Ankib1	UTSW	5	3700344	splice site	probably benign
R0564:Ankib1	UTSW	5	3729655	missense	probably damaging	0.99
R0632:Ankib1	UTSW	5	3772529	missense	probably benign	0.02
R0732:Ankib1	UTSW	5	3713163	missense	possibly damaging	0.89
R1678:Ankib1	UTSW	5	3706301	missense	probably damaging	0.99
R1816:Ankib1	UTSW	5	3734028	missense	probably benign	0.05
R2165:Ankib1	UTSW	5	3713210	missense	possibly damaging	0.69
R3434:Ankib1	UTSW	5	3692760	missense	probably damaging	1.00
R3749:Ankib1	UTSW	5	3734097	missense	probably damaging	0.98
R4745:Ankib1	UTSW	5	3732566	missense	probably damaging	1.00
R4827:Ankib1	UTSW	5	3701907	missense	probably damaging	1.00
R4983:Ankib1	UTSW	5	3769652	missense	probably benign	0.09
R4989:Ankib1	UTSW	5	3713217	missense	probably damaging	0.99
R5022:Ankib1	UTSW	5	3734011	missense	possibly damaging	0.96
R5057:Ankib1	UTSW	5	3734011	missense	possibly damaging	0.96
R5510:Ankib1	UTSW	5	3729693	missense	probably benign	0.02
R5606:Ankib1	UTSW	5	3701907	missense	probably damaging	1.00
R5910:Ankib1	UTSW	5	3693217	missense	probably benign
R5929:Ankib1	UTSW	5	3769633	missense	possibly damaging	0.86
R5986:Ankib1	UTSW	5	3747071	missense	probably damaging	1.00
R6281:Ankib1	UTSW	5	3701965	missense	possibly damaging	0.70
R6336:Ankib1	UTSW	5	3700377	nonsense	probably null
R6377:Ankib1	UTSW	5	3693855	missense	possibly damaging	0.78
R7001:Ankib1	UTSW	5	3694781	missense	probably benign
R7264:Ankib1	UTSW	5	3755739	missense	probably damaging	1.00
R7380:Ankib1	UTSW	5	3722576	missense	probably benign	0.03
R7402:Ankib1	UTSW	5	3769586	missense	probably benign	0.01
R7491:Ankib1	UTSW	5	3701911	missense	probably damaging	1.00
R7525:Ankib1	UTSW	5	3755734	missense	possibly damaging	0.95
R7562:Ankib1	UTSW	5	3747021	missense	probably null	1.00
R8116:Ankib1	UTSW	5	3702995	missense	probably damaging	1.00
R8347:Ankib1	UTSW	5	3747065	missense	probably damaging	1.00
Z1088:Ankib1	UTSW	5	3713136	missense	probably damaging	1.00
Z1088:Ankib1	UTSW	5	3713137	nonsense	probably null
Z1176:Ankib1	UTSW	5	3692763	missense	probably benign

Posted On

2013-10-07