Incidental Mutation 'IGL01336:Gm8394'
ID74629
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm8394
Ensembl Gene ENSMUSG00000050490
Gene Namepredicted gene 8394
Synonyms
Accession Numbers
Is this an essential gene? Probably essential (E-score: 0.876) question?
Stock #IGL01336
Quality Score
Status
Chromosome10
Chromosomal Location85313488-85314439 bp(+) (GRCm38)
Type of Mutationexon
DNA Base Change (assembly) T to C at 85314164 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
Predicted Effect noncoding transcript
Transcript: ENSMUST00000079684
SMART Domains Protein: ENSMUSP00000078625
Gene: ENSMUSG00000050490

DomainStartEndE-ValueType
Proteasome_A_N 8 30 6.32e-8 SMART
Pfam:Proteasome 31 220 5.6e-57 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 32 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acly G T 11: 100,495,910 L599I probably benign Het
Adcyap1 A G 17: 93,203,964 D122G probably benign Het
Ahr A G 12: 35,503,840 V760A probably benign Het
Ankrd7 T C 6: 18,868,278 V133A probably benign Het
Bsn A G 9: 108,111,785 V2256A probably damaging Het
Cblb A G 16: 52,186,229 K765E probably benign Het
Clmp A G 9: 40,782,610 *374W probably null Het
Ddc A G 11: 11,846,630 probably null Het
Dnah10 A G 5: 124,775,512 Y1878C probably damaging Het
Ei24 A G 9: 36,786,481 probably null Het
Gm12394 T A 4: 42,793,784 Q116L possibly damaging Het
Ikbke A G 1: 131,273,756 M118T probably damaging Het
Il6st T C 13: 112,480,239 S107P possibly damaging Het
Map2k6 A G 11: 110,496,411 Y203C probably damaging Het
Mettl27 C T 5: 134,935,880 probably benign Het
Mrps14 G A 1: 160,196,995 W32* probably null Het
Naaa A C 5: 92,265,133 M208R probably benign Het
Nat2 A G 8: 67,501,541 Y101C probably damaging Het
Ncoa3 A G 2: 166,054,523 S449G probably benign Het
Olfr1507 A G 14: 52,490,748 I72T probably damaging Het
Olfr5 T C 7: 6,480,998 I53V probably benign Het
Phykpl G A 11: 51,599,456 probably benign Het
Rasgrf1 A T 9: 89,991,530 M631L probably benign Het
Rgma G A 7: 73,409,318 V57M possibly damaging Het
Samd4b G T 7: 28,413,963 D192E probably benign Het
Sesn2 T C 4: 132,499,367 T139A probably benign Het
Slc30a6 A G 17: 74,408,839 probably benign Het
Stra8 T C 6: 34,933,188 Y182H possibly damaging Het
Trim31 C A 17: 36,909,377 A395E probably damaging Het
Trp53bp2 G T 1: 182,431,583 R67L probably damaging Het
Trpa1 A C 1: 14,886,880 probably benign Het
Wdr91 G A 6: 34,909,543 probably benign Het
Other mutations in Gm8394
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01467:Gm8394 APN 10 85314122 exon noncoding transcript
IGL02638:Gm8394 APN 10 85313834 exon noncoding transcript
IGL03253:Gm8394 APN 10 85313692 exon noncoding transcript
R1929:Gm8394 UTSW 10 85313731 exon noncoding transcript
R2271:Gm8394 UTSW 10 85313731 exon noncoding transcript
R2893:Gm8394 UTSW 10 85313984 exon noncoding transcript
R4689:Gm8394 UTSW 10 85314201 exon noncoding transcript
R4711:Gm8394 UTSW 10 85313803 exon noncoding transcript
R5537:Gm8394 UTSW 10 85314049 exon noncoding transcript
R5934:Gm8394 UTSW 10 85314281 exon noncoding transcript
T0722:Gm8394 UTSW 10 85313593 exon noncoding transcript
Posted On2013-10-07