Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00336:Aox1'

7471

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Aox1

Ensembl Gene

ENSMUSG00000063558

Gene Name

aldehyde oxidase 1

Synonyms

Aox-1, retinal oxidase, Aox-2, Aox2

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL00336

Quality Score

Status

Chromosome

Chromosomal Location

58069090-58145572 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 58098203 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Glutamine at position 305 (L305Q)

Ref Sequence

ENSEMBL: ENSMUSP00000001027 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000001027]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000001027
AA Change: L305Q

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000001027
Gene: ENSMUSG00000063558
AA Change: L305Q

Domain	Start	End	E-Value	Type
Pfam:Fer2	8	78	8.5e-11	PFAM
Pfam:Fer2_2	87	161	2.4e-32	PFAM
low complexity region	197	209	N/A	INTRINSIC
Pfam:FAD_binding_5	238	418	1.2e-46	PFAM
CO_deh_flav_C	425	529	8.06e-24	SMART
Ald_Xan_dh_C	593	696	6.99e-42	SMART
Pfam:Ald_Xan_dh_C2	707	1240	2.1e-176	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000160168

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 59 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A430033K04Rik	A	G	5: 138,645,366 (GRCm39)	Y417C	probably damaging	Het
Adam28	T	A	14: 68,859,569 (GRCm39)	H548L	possibly damaging	Het
Agbl3	A	T	6: 34,823,771 (GRCm39)	D812V	probably damaging	Het
Aopep	A	T	13: 63,163,237 (GRCm39)	D86V	possibly damaging	Het
Arhgef38	A	G	3: 132,837,812 (GRCm39)	V706A	probably benign	Het
Arl15	A	G	13: 114,291,288 (GRCm39)	I171V	probably benign	Het
Cacna1s	C	A	1: 136,012,011 (GRCm39)	Y237*	probably null	Het
Ccnt1	T	C	15: 98,462,990 (GRCm39)	T61A	possibly damaging	Het
Col25a1	T	A	3: 129,975,433 (GRCm39)		probably benign	Het
Col4a1	T	A	8: 11,290,077 (GRCm39)		probably benign	Het
Dcun1d1	T	C	3: 35,970,455 (GRCm39)	E130G	possibly damaging	Het
Dnah7b	G	A	1: 46,181,309 (GRCm39)	M1065I	probably benign	Het
Ephb2	T	G	4: 136,384,795 (GRCm39)	K872T	probably damaging	Het
Fga	G	A	3: 82,938,981 (GRCm39)	G452D	probably damaging	Het
Flrt1	T	A	19: 7,074,277 (GRCm39)	N90I	probably damaging	Het
Fut10	T	A	8: 31,685,319 (GRCm39)		probably null	Het
Gm4553	T	C	7: 141,718,964 (GRCm39)	S155G	unknown	Het
Gpr137b	T	C	13: 13,549,000 (GRCm39)		probably benign	Het
Gprc5d	G	A	6: 135,093,488 (GRCm39)	Q140*	probably null	Het
Ifi27l2b	T	C	12: 103,417,476 (GRCm39)	K237R	unknown	Het
Ipo8	A	T	6: 148,684,284 (GRCm39)	M836K	possibly damaging	Het
Kcnq4	G	A	4: 120,555,213 (GRCm39)	Q657*	probably null	Het
Lama1	A	T	17: 68,120,943 (GRCm39)	H2693L	probably benign	Het
Lrrc23	A	G	6: 124,755,889 (GRCm39)	W40R	probably damaging	Het
Minar1	T	C	9: 89,485,196 (GRCm39)	D67G	probably damaging	Het
Morn2	C	A	17: 80,602,933 (GRCm39)		probably benign	Het
Ms4a6b	T	A	19: 11,506,854 (GRCm39)	N214K	possibly damaging	Het
Nags	A	T	11: 102,039,892 (GRCm39)	S527C	probably damaging	Het
Ndst1	C	T	18: 60,841,028 (GRCm39)	G218D	probably damaging	Het
Or10j5	G	A	1: 172,785,045 (GRCm39)	V228M	probably benign	Het
Or5b94	T	A	19: 12,651,924 (GRCm39)	Y118*	probably null	Het
Or8h7	C	T	2: 86,720,589 (GRCm39)	C310Y	probably benign	Het
Oxa1l	G	T	14: 54,600,802 (GRCm39)	G92*	probably null	Het
Parp16	A	T	9: 65,137,245 (GRCm39)	E157V	probably damaging	Het
Pcdh17	A	T	14: 84,684,984 (GRCm39)	I484F	probably damaging	Het
Pex16	A	G	2: 92,209,580 (GRCm39)	R263G	probably benign	Het
Pkd1l3	G	A	8: 110,356,869 (GRCm39)	E765K	possibly damaging	Het
Plce1	T	C	19: 38,640,350 (GRCm39)	V532A	probably damaging	Het
Polq	A	G	16: 36,885,609 (GRCm39)		probably benign	Het
Pramel5	T	C	4: 143,998,191 (GRCm39)	T351A	probably damaging	Het
Prokr1	A	T	6: 87,565,593 (GRCm39)	I84N	probably damaging	Het
Prss30	A	T	17: 24,192,695 (GRCm39)	S162T	probably benign	Het
Ranbp2	A	G	10: 58,287,806 (GRCm39)	K25E	probably damaging	Het
Rapsn	A	G	2: 90,866,205 (GRCm39)	T22A	probably damaging	Het
Rhoj	G	T	12: 75,355,680 (GRCm39)	G9V	probably damaging	Het
Rnf213	A	G	11: 119,340,169 (GRCm39)	R3467G	probably benign	Het
Rreb1	C	A	13: 38,113,622 (GRCm39)	S327*	probably null	Het
Scn5a	G	A	9: 119,315,290 (GRCm39)	P1806L	probably damaging	Het
Sema6a	C	A	18: 47,423,042 (GRCm39)		probably null	Het
Stag3	G	A	5: 138,295,921 (GRCm39)	E416K	probably benign	Het
Stpg1	T	A	4: 135,256,856 (GRCm39)	S216T	possibly damaging	Het
Tfeb	C	A	17: 48,102,589 (GRCm39)	N426K	probably benign	Het
Trp53bp1	G	T	2: 121,087,060 (GRCm39)	Q199K	possibly damaging	Het
Ubr4	A	G	4: 139,155,877 (GRCm39)	D2234G	probably damaging	Het
Ush1c	T	G	7: 45,846,194 (GRCm39)	Q866P	probably benign	Het
Vdr	T	A	15: 97,782,735 (GRCm39)	D29V	probably damaging	Het
Vps13c	T	C	9: 67,853,224 (GRCm39)	V2439A	probably benign	Het
Xirp2	T	C	2: 67,342,942 (GRCm39)	S1728P	possibly damaging	Het
Zfp9	A	G	6: 118,441,436 (GRCm39)	S409P	probably damaging	Het

Other mutations in Aox1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01014:Aox1	APN	1	58,361,960 (GRCm39)	missense	possibly damaging	0.73
IGL01077:Aox1	APN	1	58,096,569 (GRCm39)	splice site	probably benign
IGL01288:Aox1	APN	1	58,333,566 (GRCm39)	missense	probably damaging	0.99
IGL01335:Aox1	APN	1	58,121,312 (GRCm39)	nonsense	probably null
IGL01383:Aox1	APN	1	58,333,464 (GRCm39)	missense	probably benign	0.09
IGL01410:Aox1	APN	1	58,145,184 (GRCm39)	splice site	probably null
IGL01684:Aox1	APN	1	58,116,740 (GRCm39)	splice site	probably null
IGL01727:Aox1	APN	1	58,112,387 (GRCm39)	nonsense	probably null
IGL01734:Aox1	APN	1	58,393,469 (GRCm39)	missense	possibly damaging	0.95
IGL01793:Aox1	APN	1	58,375,783 (GRCm39)	missense	possibly damaging	0.79
IGL01805:Aox1	APN	1	58,120,672 (GRCm39)	missense	possibly damaging	0.94
IGL01834:Aox1	APN	1	58,348,183 (GRCm39)	missense	possibly damaging	0.90
IGL01924:Aox1	APN	1	58,326,902 (GRCm39)	missense	possibly damaging	0.90
IGL01996:Aox1	APN	1	58,121,225 (GRCm39)	missense	probably benign	0.11
IGL02060:Aox1	APN	1	58,137,114 (GRCm39)	missense	possibly damaging	0.95
IGL02206:Aox1	APN	1	58,104,499 (GRCm39)	missense	probably benign	0.00
IGL02591:Aox1	APN	1	58,398,158 (GRCm39)	nonsense	probably null
IGL02645:Aox1	APN	1	58,373,883 (GRCm39)	missense	probably damaging	1.00
IGL02710:Aox1	APN	1	58,373,928 (GRCm39)	critical splice donor site	probably null
IGL02801:Aox1	APN	1	58,393,336 (GRCm39)	missense	probably damaging	1.00
IGL02839:Aox1	APN	1	58,107,943 (GRCm39)	missense	probably benign	0.05
IGL02975:Aox1	APN	1	58,107,550 (GRCm39)	missense	probably damaging	1.00
IGL02988:Aox1	APN	1	58,376,509 (GRCm39)	missense	probably benign
IGL03062:Aox1	APN	1	58,117,624 (GRCm39)	missense	probably benign	0.01
IGL03104:Aox1	APN	1	58,321,918 (GRCm39)	missense	probably benign
IGL03121:Aox1	APN	1	58,398,113 (GRCm39)	missense	probably damaging	1.00
IGL03191:Aox1	APN	1	58,398,228 (GRCm39)	missense	probably null	0.98
IGL03236:Aox1	APN	1	58,349,156 (GRCm39)	nonsense	probably null
IGL03286:Aox1	APN	1	58,088,543 (GRCm39)	missense	probably benign	0.19
IGL03335:Aox1	APN	1	58,115,319 (GRCm39)	missense	probably damaging	0.98
IGL03395:Aox1	APN	1	58,107,884 (GRCm39)	splice site	probably benign
IGL03409:Aox1	APN	1	58,393,588 (GRCm39)	missense	possibly damaging	0.91
PIT4362001:Aox1	UTSW	1	58,321,839 (GRCm39)	missense	probably damaging	1.00
R0035:Aox1	UTSW	1	58,393,581 (GRCm39)	missense	probably benign	0.00
R0035:Aox1	UTSW	1	58,393,581 (GRCm39)	missense	probably benign	0.00
R0048:Aox1	UTSW	1	58,112,371 (GRCm39)	missense	probably damaging	0.98
R0144:Aox1	UTSW	1	58,109,233 (GRCm39)	missense	probably benign	0.00
R0207:Aox1	UTSW	1	58,144,173 (GRCm39)	missense	possibly damaging	0.82
R0267:Aox1	UTSW	1	58,378,605 (GRCm39)	splice site	probably benign
R0357:Aox1	UTSW	1	58,131,675 (GRCm39)	missense	probably damaging	1.00
R0383:Aox1	UTSW	1	58,100,400 (GRCm39)	missense	probably benign	0.00
R0388:Aox1	UTSW	1	58,393,565 (GRCm39)	missense	probably damaging	1.00
R0399:Aox1	UTSW	1	58,108,008 (GRCm39)	splice site	probably null
R0409:Aox1	UTSW	1	58,375,783 (GRCm39)	missense	possibly damaging	0.90
R0465:Aox1	UTSW	1	58,101,366 (GRCm39)	missense	probably damaging	1.00
R0480:Aox1	UTSW	1	58,082,810 (GRCm39)	splice site	probably benign
R0547:Aox1	UTSW	1	58,349,201 (GRCm39)	missense	probably damaging	0.96
R0630:Aox1	UTSW	1	58,376,480 (GRCm39)	splice site	probably benign
R0726:Aox1	UTSW	1	58,373,941 (GRCm39)	splice site	probably benign
R0734:Aox1	UTSW	1	58,344,500 (GRCm39)	missense	probably benign	0.22
R0831:Aox1	UTSW	1	58,378,842 (GRCm39)	missense	probably benign	0.28
R0961:Aox1	UTSW	1	58,349,230 (GRCm39)	missense	probably benign	0.00
R1005:Aox1	UTSW	1	58,104,511 (GRCm39)	missense	probably benign	0.00
R1404:Aox1	UTSW	1	58,385,371 (GRCm39)	splice site	probably benign
R1507:Aox1	UTSW	1	58,143,610 (GRCm39)	missense	probably benign	0.01
R1512:Aox1	UTSW	1	58,346,510 (GRCm39)	missense	probably benign	0.00
R1573:Aox1	UTSW	1	58,348,186 (GRCm39)	missense	probably benign	0.00
R1592:Aox1	UTSW	1	58,339,853 (GRCm39)	missense	probably benign	0.00
R1597:Aox1	UTSW	1	58,086,326 (GRCm39)	missense	probably damaging	1.00
R1693:Aox1	UTSW	1	58,124,701 (GRCm39)	missense	probably damaging	1.00
R1709:Aox1	UTSW	1	58,116,633 (GRCm39)	missense	probably benign
R1747:Aox1	UTSW	1	58,378,751 (GRCm39)	missense	probably benign	0.01
R1768:Aox1	UTSW	1	58,393,354 (GRCm39)	missense	probably benign	0.00
R1809:Aox1	UTSW	1	58,333,484 (GRCm39)	missense	probably benign
R1823:Aox1	UTSW	1	58,351,518 (GRCm39)	missense	probably benign	0.02
R1834:Aox1	UTSW	1	58,348,150 (GRCm39)	missense	probably benign	0.08
R1835:Aox1	UTSW	1	58,348,150 (GRCm39)	missense	probably benign	0.08
R1836:Aox1	UTSW	1	58,348,150 (GRCm39)	missense	probably benign	0.08
R1869:Aox1	UTSW	1	58,115,262 (GRCm39)	missense	probably damaging	1.00
R1870:Aox1	UTSW	1	58,115,262 (GRCm39)	missense	probably damaging	1.00
R1898:Aox1	UTSW	1	58,117,601 (GRCm39)	missense	probably damaging	1.00
R1908:Aox1	UTSW	1	58,141,783 (GRCm39)	missense	probably damaging	1.00
R2002:Aox1	UTSW	1	58,086,300 (GRCm39)	missense	possibly damaging	0.69
R2062:Aox1	UTSW	1	58,098,351 (GRCm39)	splice site	probably null
R2065:Aox1	UTSW	1	58,098,351 (GRCm39)	splice site	probably null
R2219:Aox1	UTSW	1	58,388,289 (GRCm39)	splice site	probably null
R2220:Aox1	UTSW	1	58,388,289 (GRCm39)	splice site	probably null
R2265:Aox1	UTSW	1	58,120,679 (GRCm39)	missense	probably damaging	0.99
R2508:Aox1	UTSW	1	58,382,832 (GRCm39)	missense	probably benign	0.38
R2942:Aox1	UTSW	1	58,376,540 (GRCm39)	missense	probably benign	0.03
R2967:Aox1	UTSW	1	58,361,993 (GRCm39)	missense	probably damaging	0.96
R3082:Aox1	UTSW	1	58,322,759 (GRCm39)	splice site	probably benign
R3161:Aox1	UTSW	1	58,343,597 (GRCm39)	missense	possibly damaging	0.91
R3408:Aox1	UTSW	1	58,382,827 (GRCm39)	missense	probably benign	0.32
R3713:Aox1	UTSW	1	58,095,374 (GRCm39)	missense	probably benign	0.01
R3778:Aox1	UTSW	1	58,092,862 (GRCm39)	missense	possibly damaging	0.89
R3803:Aox1	UTSW	1	58,329,058 (GRCm39)	splice site	probably null
R3894:Aox1	UTSW	1	58,373,837 (GRCm39)	critical splice acceptor site	probably null
R4198:Aox1	UTSW	1	58,124,766 (GRCm39)	missense	probably benign
R4214:Aox1	UTSW	1	58,346,603 (GRCm39)	critical splice donor site	probably null
R4249:Aox1	UTSW	1	58,338,978 (GRCm39)	missense	probably benign	0.01
R4296:Aox1	UTSW	1	58,096,559 (GRCm39)	splice site	probably null
R4562:Aox1	UTSW	1	58,098,215 (GRCm39)	missense	probably damaging	0.99
R4666:Aox1	UTSW	1	58,343,756 (GRCm39)	nonsense	probably null
R4668:Aox1	UTSW	1	58,373,853 (GRCm39)	missense	possibly damaging	0.63
R4703:Aox1	UTSW	1	58,398,116 (GRCm39)	missense	possibly damaging	0.78
R4758:Aox1	UTSW	1	58,371,741 (GRCm39)	missense	probably benign	0.00
R4858:Aox1	UTSW	1	58,143,640 (GRCm39)	missense	probably benign
R4862:Aox1	UTSW	1	58,134,316 (GRCm39)	missense	probably damaging	0.98
R4890:Aox1	UTSW	1	58,373,862 (GRCm39)	missense	probably benign	0.11
R4900:Aox1	UTSW	1	58,344,544 (GRCm39)	missense	probably benign
R4924:Aox1	UTSW	1	58,344,503 (GRCm39)	missense	probably damaging	1.00
R4970:Aox1	UTSW	1	58,349,254 (GRCm39)	splice site	probably null
R5048:Aox1	UTSW	1	58,098,641 (GRCm39)	splice site	probably benign
R5112:Aox1	UTSW	1	58,349,254 (GRCm39)	splice site	probably null
R5127:Aox1	UTSW	1	58,069,185 (GRCm39)	missense	probably benign	0.00
R5139:Aox1	UTSW	1	58,100,456 (GRCm39)	missense	probably benign	0.03
R5157:Aox1	UTSW	1	58,109,222 (GRCm39)	missense	probably damaging	1.00
R5168:Aox1	UTSW	1	58,088,561 (GRCm39)	missense	probably damaging	1.00
R5186:Aox1	UTSW	1	58,107,529 (GRCm39)	missense	probably damaging	1.00
R5235:Aox1	UTSW	1	58,096,714 (GRCm39)	missense	possibly damaging	0.77
R5289:Aox1	UTSW	1	58,131,717 (GRCm39)	missense	probably damaging	0.99
R5466:Aox1	UTSW	1	58,080,619 (GRCm39)	missense	probably damaging	1.00
R5540:Aox1	UTSW	1	58,143,569 (GRCm39)	missense	probably benign	0.03
R5615:Aox1	UTSW	1	58,136,125 (GRCm39)	missense	probably benign
R5652:Aox1	UTSW	1	58,134,356 (GRCm39)	missense	probably damaging	1.00
R5920:Aox1	UTSW	1	58,088,631 (GRCm39)	missense	probably damaging	1.00
R5987:Aox1	UTSW	1	58,346,518 (GRCm39)	missense	probably benign	0.00
R6008:Aox1	UTSW	1	58,116,672 (GRCm39)	missense	probably damaging	1.00
R6073:Aox1	UTSW	1	58,143,668 (GRCm39)	critical splice donor site	probably null
R6215:Aox1	UTSW	1	58,124,620 (GRCm39)	missense	probably benign
R6239:Aox1	UTSW	1	58,344,550 (GRCm39)	critical splice donor site	probably null
R6273:Aox1	UTSW	1	58,378,831 (GRCm39)	missense	probably benign	0.00
R6291:Aox1	UTSW	1	58,369,965 (GRCm39)	missense	probably damaging	0.98
R6334:Aox1	UTSW	1	58,346,566 (GRCm39)	nonsense	probably null
R6403:Aox1	UTSW	1	58,107,594 (GRCm39)	missense	probably damaging	1.00
R6440:Aox1	UTSW	1	58,133,631 (GRCm39)	missense	probably damaging	1.00
R6601:Aox1	UTSW	1	58,102,665 (GRCm39)	missense	probably damaging	1.00
R6608:Aox1	UTSW	1	58,096,705 (GRCm39)	missense	probably benign	0.40
R6752:Aox1	UTSW	1	58,086,398 (GRCm39)	missense	probably benign	0.00
R6764:Aox1	UTSW	1	58,389,441 (GRCm39)	missense	probably damaging	0.97
R6766:Aox1	UTSW	1	58,388,227 (GRCm39)	missense	possibly damaging	0.95
R6789:Aox1	UTSW	1	58,343,644 (GRCm39)	missense	probably benign	0.01
R6804:Aox1	UTSW	1	58,343,757 (GRCm39)	missense	probably benign	0.04
R6989:Aox1	UTSW	1	58,124,611 (GRCm39)	missense	probably damaging	1.00
R7007:Aox1	UTSW	1	58,370,051 (GRCm39)	missense	probably damaging	1.00
R7015:Aox1	UTSW	1	58,321,917 (GRCm39)	missense	probably benign	0.00
R7042:Aox1	UTSW	1	58,141,759 (GRCm39)	missense	probably damaging	0.99
R7055:Aox1	UTSW	1	58,338,927 (GRCm39)	missense	probably benign	0.08
R7089:Aox1	UTSW	1	58,375,808 (GRCm39)	missense	probably benign	0.01
R7157:Aox1	UTSW	1	58,322,651 (GRCm39)	missense	probably benign	0.00
R7303:Aox1	UTSW	1	58,373,924 (GRCm39)	nonsense	probably null
R7426:Aox1	UTSW	1	58,329,142 (GRCm39)	nonsense	probably null
R7442:Aox1	UTSW	1	58,121,172 (GRCm39)	missense	probably damaging	1.00
R7506:Aox1	UTSW	1	58,088,562 (GRCm39)	missense	probably damaging	1.00
R7563:Aox1	UTSW	1	58,086,304 (GRCm39)	missense	probably benign	0.32
R7589:Aox1	UTSW	1	58,080,643 (GRCm39)	missense	probably damaging	1.00
R7735:Aox1	UTSW	1	58,107,451 (GRCm39)	missense	probably benign	0.01
R7762:Aox1	UTSW	1	58,388,263 (GRCm39)	missense	probably damaging	1.00
R7814:Aox1	UTSW	1	58,124,626 (GRCm39)	missense	probably benign
R7876:Aox1	UTSW	1	58,101,330 (GRCm39)	nonsense	probably null
R7899:Aox1	UTSW	1	58,320,396 (GRCm39)	splice site	probably null
R7905:Aox1	UTSW	1	58,143,557 (GRCm39)	missense	possibly damaging	0.72
R7908:Aox1	UTSW	1	58,145,227 (GRCm39)	missense	possibly damaging	0.68
R7942:Aox1	UTSW	1	58,376,590 (GRCm39)	missense	probably damaging	1.00
R7975:Aox1	UTSW	1	58,348,187 (GRCm39)	missense	probably benign	0.02
R8029:Aox1	UTSW	1	58,382,827 (GRCm39)	missense	probably benign	0.32
R8032:Aox1	UTSW	1	58,389,442 (GRCm39)	missense	probably benign	0.01
R8116:Aox1	UTSW	1	58,115,283 (GRCm39)	missense	probably damaging	1.00
R8147:Aox1	UTSW	1	58,339,821 (GRCm39)	missense	probably benign	0.02
R8165:Aox1	UTSW	1	58,348,088 (GRCm39)	missense	probably benign	0.08
R8179:Aox1	UTSW	1	58,137,117 (GRCm39)	missense	probably damaging	1.00
R8264:Aox1	UTSW	1	58,092,873 (GRCm39)	missense	possibly damaging	0.92
R8284:Aox1	UTSW	1	58,115,250 (GRCm39)	missense	probably damaging	1.00
R8326:Aox1	UTSW	1	58,335,046 (GRCm39)	missense	probably benign
R8415:Aox1	UTSW	1	58,080,638 (GRCm39)	missense	probably damaging	1.00
R8770:Aox1	UTSW	1	58,378,763 (GRCm39)	missense	probably benign	0.10
R8946:Aox1	UTSW	1	58,145,227 (GRCm39)	missense	possibly damaging	0.68
R8973:Aox1	UTSW	1	58,329,113 (GRCm39)	missense	probably benign	0.34
R8988:Aox1	UTSW	1	58,088,625 (GRCm39)	missense	possibly damaging	0.48
R9015:Aox1	UTSW	1	58,382,851 (GRCm39)	missense	probably damaging	1.00
R9097:Aox1	UTSW	1	58,326,887 (GRCm39)	missense	possibly damaging	0.82
R9101:Aox1	UTSW	1	58,371,796 (GRCm39)	missense	probably benign	0.03
R9108:Aox1	UTSW	1	58,321,851 (GRCm39)	missense	probably damaging	1.00
R9180:Aox1	UTSW	1	58,378,777 (GRCm39)	nonsense	probably null
R9258:Aox1	UTSW	1	58,351,515 (GRCm39)	missense	probably damaging	1.00
R9293:Aox1	UTSW	1	58,361,953 (GRCm39)	missense	possibly damaging	0.86
R9296:Aox1	UTSW	1	58,124,612 (GRCm39)	missense	probably damaging	1.00
R9382:Aox1	UTSW	1	58,104,501 (GRCm39)	missense	possibly damaging	0.48
R9461:Aox1	UTSW	1	58,116,736 (GRCm39)	critical splice donor site	probably null
R9519:Aox1	UTSW	1	58,373,926 (GRCm39)	missense	probably damaging	0.98
R9581:Aox1	UTSW	1	58,370,055 (GRCm39)	critical splice donor site	probably null
Z1088:Aox1	UTSW	1	58,120,701 (GRCm39)	missense	probably benign	0.01
Z1177:Aox1	UTSW	1	58,393,556 (GRCm39)	missense	possibly damaging	0.69

Posted On

2012-04-20