Incidental Mutation 'IGL01300:Ros1'
ID 75238
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ros1
Ensembl Gene ENSMUSG00000019893
Gene Name Ros1 proto-oncogene
Synonyms Ros-1, c-ros
Accession Numbers
Essential gene? Probably non essential (E-score: 0.145) question?
Stock # IGL01300
Quality Score
Status
Chromosome 10
Chromosomal Location 51921817-52071340 bp(-) (GRCm39)
Type of Mutation missense
DNA Base Change (assembly) A to G at 51977809 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change Methionine to Threonine at position 1479 (M1479T)
Ref Sequence ENSEMBL: ENSMUSP00000151720 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000020045] [ENSMUST00000218452] [ENSMUST00000219173] [ENSMUST00000219692]
AlphaFold Q78DX7
Predicted Effect probably benign
Transcript: ENSMUST00000020045
AA Change: M1500T

PolyPhen 2 Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
SMART Domains Protein: ENSMUSP00000020045
Gene: ENSMUSG00000019893
AA Change: M1500T

DomainStartEndE-ValueType
transmembrane domain 7 26 N/A INTRINSIC
FN3 109 187 1.05e-4 SMART
FN3 205 282 7.45e-10 SMART
LY 369 409 9.17e0 SMART
FN3 568 654 2.24e-4 SMART
LY 734 776 2.28e1 SMART
LY 777 815 4.61e0 SMART
FN3 944 1023 5.53e-4 SMART
FN3 1037 1133 1.07e1 SMART
FN3 1440 1532 1.19e1 SMART
FN3 1551 1637 2.11e0 SMART
FN3 1649 1731 6.8e-4 SMART
FN3 1746 1832 2.7e1 SMART
TyrKc 1938 2208 1.3e-145 SMART
low complexity region 2294 2307 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000117992
AA Change: M1479T

PolyPhen 2 Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
SMART Domains Protein: ENSMUSP00000112873
Gene: ENSMUSG00000019893
AA Change: M1479T

DomainStartEndE-ValueType
transmembrane domain 7 26 N/A INTRINSIC
FN3 109 187 1.05e-4 SMART
FN3 205 282 7.45e-10 SMART
LY 369 409 9.17e0 SMART
FN3 547 633 2.24e-4 SMART
LY 713 755 2.28e1 SMART
LY 756 794 4.61e0 SMART
FN3 923 1002 5.53e-4 SMART
FN3 1016 1112 1.07e1 SMART
FN3 1419 1511 1.19e1 SMART
FN3 1530 1616 2.11e0 SMART
FN3 1628 1710 6.8e-4 SMART
FN3 1725 1811 2.7e1 SMART
TyrKc 1917 2187 1.3e-145 SMART
low complexity region 2273 2286 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000177378
AA Change: M1479T

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
SMART Domains Protein: ENSMUSP00000134905
Gene: ENSMUSG00000019893
AA Change: M1479T

DomainStartEndE-ValueType
transmembrane domain 7 26 N/A INTRINSIC
FN3 109 187 1.05e-4 SMART
FN3 205 282 7.45e-10 SMART
LY 369 409 9.17e0 SMART
FN3 547 633 2.24e-4 SMART
LY 713 755 2.28e1 SMART
LY 756 794 4.61e0 SMART
FN3 923 1002 5.53e-4 SMART
FN3 1016 1112 1.07e1 SMART
Blast:LY 1190 1236 2e-18 BLAST
FN3 1419 1511 1.19e1 SMART
FN3 1530 1616 2.11e0 SMART
FN3 1628 1710 6.8e-4 SMART
FN3 1725 1811 2.7e1 SMART
transmembrane domain 1832 1854 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000218452
AA Change: M1479T

PolyPhen 2 Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)
Predicted Effect probably benign
Transcript: ENSMUST00000219173
AA Change: M1479T

PolyPhen 2 Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
Predicted Effect probably benign
Transcript: ENSMUST00000219692
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygotes for targeted null mutations exhibit male infertility due to impaired sperm maturation in the epididymis. Mutant sperm are capable of fertilization in vitro but not in vivo. [provided by MGI curators]
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Anxa8 A G 14: 33,821,700 (GRCm39) D300G probably benign Het
Cacna1g T C 11: 94,324,738 (GRCm39) H1161R probably benign Het
Col14a1 G A 15: 55,331,372 (GRCm39) R1471Q unknown Het
Gm14496 A T 2: 181,642,753 (GRCm39) E808V probably damaging Het
Gm1968 T C 16: 29,781,038 (GRCm39) noncoding transcript Het
Gzmb G A 14: 56,497,653 (GRCm39) R196C probably benign Het
Hkdc1 A G 10: 62,231,040 (GRCm39) probably benign Het
Itgal T A 7: 126,913,290 (GRCm39) V629E probably damaging Het
Jak2 T A 19: 29,287,083 (GRCm39) Y1050N probably damaging Het
Lrrc69 C T 4: 14,773,663 (GRCm39) probably benign Het
Mmd T C 11: 90,140,537 (GRCm39) M1T probably null Het
Myh6 A G 14: 55,200,548 (GRCm39) V191A possibly damaging Het
Mynn A G 3: 30,667,755 (GRCm39) N485S probably damaging Het
Naa30 C T 14: 49,410,714 (GRCm39) T214M probably damaging Het
Ncoa3 A T 2: 165,910,381 (GRCm39) T1265S probably benign Het
Or10al2 C A 17: 37,983,778 (GRCm39) T288K probably damaging Het
Or1j10 T C 2: 36,267,054 (GRCm39) S89P probably benign Het
Prex1 A G 2: 166,480,327 (GRCm39) C138R possibly damaging Het
Prom2 A T 2: 127,377,009 (GRCm39) L535H probably benign Het
Pros1 T C 16: 62,734,174 (GRCm39) F327L possibly damaging Het
Scn9a G A 2: 66,318,397 (GRCm39) Q1465* probably null Het
Serpinb3b A G 1: 107,083,573 (GRCm39) probably benign Het
Sipa1l3 G A 7: 29,099,253 (GRCm39) Q339* probably null Het
Slc34a2 A C 5: 53,225,469 (GRCm39) probably null Het
Smc3 T A 19: 53,630,283 (GRCm39) probably benign Het
Tmem30a A G 9: 79,682,382 (GRCm39) probably null Het
Trappc11 A T 8: 47,954,903 (GRCm39) D878E probably benign Het
Trrap C T 5: 144,741,628 (GRCm39) T1325M probably damaging Het
Ttc12 A T 9: 49,359,222 (GRCm39) probably benign Het
Vmn1r237 T A 17: 21,534,337 (GRCm39) I20N probably damaging Het
Vmn2r115 T A 17: 23,578,755 (GRCm39) S743T probably damaging Het
Vmn2r74 A G 7: 85,606,414 (GRCm39) Y311H probably benign Het
Vnn3 T A 10: 23,740,263 (GRCm39) F189I possibly damaging Het
Other mutations in Ros1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00236:Ros1 APN 10 52,070,986 (GRCm39) missense probably benign 0.01
IGL00338:Ros1 APN 10 52,001,907 (GRCm39) missense probably benign
IGL00419:Ros1 APN 10 51,967,150 (GRCm39) missense probably damaging 0.97
IGL00840:Ros1 APN 10 52,020,969 (GRCm39) missense possibly damaging 0.92
IGL00841:Ros1 APN 10 52,020,969 (GRCm39) missense possibly damaging 0.92
IGL00951:Ros1 APN 10 52,019,348 (GRCm39) missense probably damaging 0.99
IGL01123:Ros1 APN 10 51,996,905 (GRCm39) missense probably damaging 1.00
IGL01128:Ros1 APN 10 52,018,424 (GRCm39) nonsense probably null
IGL01316:Ros1 APN 10 51,963,975 (GRCm39) critical splice donor site probably null
IGL01349:Ros1 APN 10 51,927,122 (GRCm39) missense probably damaging 0.99
IGL01363:Ros1 APN 10 52,042,238 (GRCm39) missense probably damaging 1.00
IGL01457:Ros1 APN 10 51,922,426 (GRCm39) splice site probably benign
IGL01532:Ros1 APN 10 51,967,034 (GRCm39) splice site probably benign
IGL01585:Ros1 APN 10 52,031,198 (GRCm39) missense probably damaging 1.00
IGL01650:Ros1 APN 10 52,031,075 (GRCm39) missense probably damaging 0.99
IGL01672:Ros1 APN 10 51,977,899 (GRCm39) missense possibly damaging 0.92
IGL01904:Ros1 APN 10 51,954,007 (GRCm39) missense probably damaging 0.97
IGL02040:Ros1 APN 10 51,992,018 (GRCm39) missense probably damaging 0.99
IGL02053:Ros1 APN 10 52,038,816 (GRCm39) missense probably damaging 1.00
IGL02147:Ros1 APN 10 51,996,991 (GRCm39) missense probably damaging 1.00
IGL02169:Ros1 APN 10 51,958,053 (GRCm39) critical splice donor site probably null
IGL02247:Ros1 APN 10 52,005,677 (GRCm39) missense probably damaging 0.99
IGL02262:Ros1 APN 10 52,055,065 (GRCm39) missense probably damaging 0.96
IGL02307:Ros1 APN 10 52,004,534 (GRCm39) missense possibly damaging 0.53
IGL02398:Ros1 APN 10 52,020,980 (GRCm39) splice site probably benign
IGL02525:Ros1 APN 10 51,992,138 (GRCm39) missense possibly damaging 0.66
IGL02718:Ros1 APN 10 51,994,328 (GRCm39) missense probably damaging 1.00
IGL02721:Ros1 APN 10 52,048,927 (GRCm39) splice site probably benign
IGL02808:Ros1 APN 10 52,001,985 (GRCm39) missense probably damaging 1.00
IGL03009:Ros1 APN 10 52,022,003 (GRCm39) missense probably benign 0.00
IGL03035:Ros1 APN 10 51,952,080 (GRCm39) splice site probably benign
IGL03092:Ros1 APN 10 51,974,902 (GRCm39) missense probably damaging 0.99
IGL03309:Ros1 APN 10 51,994,357 (GRCm39) missense possibly damaging 0.83
IGL03333:Ros1 APN 10 52,031,267 (GRCm39) missense probably damaging 1.00
boss UTSW 10 51,967,091 (GRCm39) nonsense probably null
Chuckwagon UTSW 10 51,994,299 (GRCm39) missense probably damaging 1.00
R1005_Ros1_648 UTSW 10 52,004,501 (GRCm39) splice site probably benign
R1220_Ros1_012 UTSW 10 51,974,966 (GRCm39) missense probably damaging 0.97
R3423_Ros1_122 UTSW 10 52,004,512 (GRCm39) splice site probably null
trail UTSW 10 52,037,991 (GRCm39) nonsense probably null
R0049:Ros1 UTSW 10 51,977,857 (GRCm39) missense possibly damaging 0.66
R0049:Ros1 UTSW 10 51,977,857 (GRCm39) missense possibly damaging 0.66
R0050:Ros1 UTSW 10 51,977,899 (GRCm39) missense probably damaging 0.97
R0050:Ros1 UTSW 10 51,977,899 (GRCm39) missense probably damaging 0.97
R0057:Ros1 UTSW 10 52,056,287 (GRCm39) missense probably benign 0.00
R0057:Ros1 UTSW 10 52,056,287 (GRCm39) missense probably benign 0.00
R0106:Ros1 UTSW 10 52,018,363 (GRCm39) missense possibly damaging 0.85
R0106:Ros1 UTSW 10 52,018,363 (GRCm39) missense possibly damaging 0.85
R0125:Ros1 UTSW 10 52,001,885 (GRCm39) missense probably benign 0.38
R0403:Ros1 UTSW 10 52,019,534 (GRCm39) splice site probably benign
R0487:Ros1 UTSW 10 52,031,204 (GRCm39) missense possibly damaging 0.69
R0502:Ros1 UTSW 10 52,070,919 (GRCm39) splice site probably benign
R0557:Ros1 UTSW 10 51,961,359 (GRCm39) missense possibly damaging 0.82
R0599:Ros1 UTSW 10 51,999,396 (GRCm39) missense probably damaging 1.00
R0620:Ros1 UTSW 10 51,994,444 (GRCm39) missense probably damaging 1.00
R0679:Ros1 UTSW 10 51,942,391 (GRCm39) missense possibly damaging 0.95
R1005:Ros1 UTSW 10 52,004,501 (GRCm39) splice site probably benign
R1073:Ros1 UTSW 10 51,922,221 (GRCm39) missense probably damaging 1.00
R1220:Ros1 UTSW 10 51,974,966 (GRCm39) missense probably damaging 0.97
R1279:Ros1 UTSW 10 52,018,262 (GRCm39) missense possibly damaging 0.81
R1295:Ros1 UTSW 10 51,964,028 (GRCm39) missense possibly damaging 0.92
R1336:Ros1 UTSW 10 52,044,758 (GRCm39) missense probably damaging 1.00
R1371:Ros1 UTSW 10 51,964,041 (GRCm39) missense probably damaging 0.98
R1447:Ros1 UTSW 10 51,974,954 (GRCm39) missense possibly damaging 0.66
R1486:Ros1 UTSW 10 52,048,954 (GRCm39) missense probably damaging 1.00
R1499:Ros1 UTSW 10 51,974,773 (GRCm39) missense possibly damaging 0.92
R1669:Ros1 UTSW 10 52,037,907 (GRCm39) missense probably damaging 1.00
R1744:Ros1 UTSW 10 51,999,475 (GRCm39) missense probably damaging 0.99
R1759:Ros1 UTSW 10 51,996,922 (GRCm39) missense probably damaging 1.00
R1791:Ros1 UTSW 10 51,976,183 (GRCm39) missense probably benign 0.00
R1794:Ros1 UTSW 10 52,000,199 (GRCm39) nonsense probably null
R2031:Ros1 UTSW 10 51,943,164 (GRCm39) missense possibly damaging 0.88
R2115:Ros1 UTSW 10 52,004,651 (GRCm39) missense probably benign 0.00
R2219:Ros1 UTSW 10 52,042,175 (GRCm39) missense probably damaging 1.00
R2290:Ros1 UTSW 10 51,994,477 (GRCm39) missense probably damaging 0.96
R2329:Ros1 UTSW 10 52,038,983 (GRCm39) missense probably damaging 1.00
R2371:Ros1 UTSW 10 52,039,991 (GRCm39) missense possibly damaging 0.66
R2879:Ros1 UTSW 10 52,048,936 (GRCm39) critical splice donor site probably null
R3154:Ros1 UTSW 10 51,927,077 (GRCm39) missense probably benign
R3423:Ros1 UTSW 10 52,004,512 (GRCm39) splice site probably null
R3424:Ros1 UTSW 10 52,004,512 (GRCm39) splice site probably null
R3425:Ros1 UTSW 10 52,004,512 (GRCm39) splice site probably null
R3433:Ros1 UTSW 10 51,967,204 (GRCm39) missense probably benign 0.45
R3522:Ros1 UTSW 10 51,967,091 (GRCm39) nonsense probably null
R3686:Ros1 UTSW 10 52,021,912 (GRCm39) missense probably damaging 1.00
R3710:Ros1 UTSW 10 52,037,991 (GRCm39) nonsense probably null
R3771:Ros1 UTSW 10 52,005,087 (GRCm39) missense probably damaging 0.97
R3808:Ros1 UTSW 10 51,996,944 (GRCm39) missense probably benign 0.08
R3930:Ros1 UTSW 10 52,070,944 (GRCm39) missense possibly damaging 0.92
R3950:Ros1 UTSW 10 51,942,484 (GRCm39) missense probably damaging 1.00
R3981:Ros1 UTSW 10 51,996,974 (GRCm39) missense possibly damaging 0.46
R4007:Ros1 UTSW 10 51,994,328 (GRCm39) missense probably damaging 1.00
R4346:Ros1 UTSW 10 52,044,705 (GRCm39) missense possibly damaging 0.92
R4382:Ros1 UTSW 10 51,997,055 (GRCm39) missense possibly damaging 0.46
R4414:Ros1 UTSW 10 52,038,800 (GRCm39) critical splice donor site probably null
R4450:Ros1 UTSW 10 51,954,038 (GRCm39) missense probably damaging 0.98
R4468:Ros1 UTSW 10 51,994,452 (GRCm39) missense probably damaging 1.00
R4569:Ros1 UTSW 10 52,040,090 (GRCm39) missense probably damaging 0.99
R4649:Ros1 UTSW 10 52,005,764 (GRCm39) missense possibly damaging 0.66
R4684:Ros1 UTSW 10 52,005,192 (GRCm39) missense probably damaging 1.00
R4706:Ros1 UTSW 10 51,977,990 (GRCm39) missense possibly damaging 0.95
R4731:Ros1 UTSW 10 52,018,325 (GRCm39) missense probably damaging 1.00
R4748:Ros1 UTSW 10 51,992,093 (GRCm39) missense probably benign 0.00
R4806:Ros1 UTSW 10 51,972,271 (GRCm39) missense probably damaging 0.96
R4865:Ros1 UTSW 10 52,048,966 (GRCm39) missense probably damaging 0.99
R4973:Ros1 UTSW 10 52,031,087 (GRCm39) missense probably damaging 0.98
R5022:Ros1 UTSW 10 52,000,171 (GRCm39) missense possibly damaging 0.46
R5033:Ros1 UTSW 10 52,004,512 (GRCm39) critical splice donor site probably null
R5082:Ros1 UTSW 10 52,040,037 (GRCm39) missense possibly damaging 0.66
R5083:Ros1 UTSW 10 52,040,037 (GRCm39) missense possibly damaging 0.66
R5130:Ros1 UTSW 10 52,040,037 (GRCm39) missense possibly damaging 0.66
R5269:Ros1 UTSW 10 51,927,104 (GRCm39) missense probably damaging 1.00
R5399:Ros1 UTSW 10 51,967,040 (GRCm39) critical splice donor site probably null
R5414:Ros1 UTSW 10 52,031,189 (GRCm39) missense probably damaging 1.00
R5659:Ros1 UTSW 10 52,019,482 (GRCm39) missense possibly damaging 0.92
R5742:Ros1 UTSW 10 52,018,234 (GRCm39) critical splice donor site probably null
R5780:Ros1 UTSW 10 52,070,953 (GRCm39) missense probably damaging 1.00
R5805:Ros1 UTSW 10 51,999,385 (GRCm39) missense probably damaging 1.00
R5843:Ros1 UTSW 10 52,042,293 (GRCm39) missense possibly damaging 0.92
R5881:Ros1 UTSW 10 52,057,894 (GRCm39) missense probably benign 0.26
R6027:Ros1 UTSW 10 52,040,064 (GRCm39) missense possibly damaging 0.82
R6035:Ros1 UTSW 10 51,954,067 (GRCm39) missense probably benign
R6035:Ros1 UTSW 10 51,954,067 (GRCm39) missense probably benign
R6052:Ros1 UTSW 10 52,039,999 (GRCm39) missense probably benign 0.39
R6175:Ros1 UTSW 10 51,977,881 (GRCm39) missense probably benign 0.02
R6315:Ros1 UTSW 10 51,994,306 (GRCm39) missense probably benign
R6342:Ros1 UTSW 10 52,031,351 (GRCm39) missense probably damaging 1.00
R6470:Ros1 UTSW 10 52,042,140 (GRCm39) critical splice donor site probably null
R6527:Ros1 UTSW 10 52,019,473 (GRCm39) missense possibly damaging 0.66
R6568:Ros1 UTSW 10 52,038,908 (GRCm39) missense probably damaging 1.00
R6573:Ros1 UTSW 10 52,031,106 (GRCm39) missense possibly damaging 0.84
R6653:Ros1 UTSW 10 52,018,299 (GRCm39) missense probably damaging 1.00
R6959:Ros1 UTSW 10 52,040,090 (GRCm39) missense probably damaging 0.99
R7011:Ros1 UTSW 10 52,056,272 (GRCm39) missense probably damaging 1.00
R7111:Ros1 UTSW 10 52,057,906 (GRCm39) missense probably benign 0.02
R7243:Ros1 UTSW 10 51,999,477 (GRCm39) missense probably damaging 1.00
R7355:Ros1 UTSW 10 52,042,175 (GRCm39) missense probably damaging 1.00
R7385:Ros1 UTSW 10 52,031,222 (GRCm39) missense probably benign 0.00
R7460:Ros1 UTSW 10 51,994,299 (GRCm39) missense probably damaging 1.00
R7549:Ros1 UTSW 10 52,021,930 (GRCm39) missense probably damaging 0.96
R7573:Ros1 UTSW 10 52,046,072 (GRCm39) missense probably benign 0.03
R7650:Ros1 UTSW 10 51,922,305 (GRCm39) missense probably benign 0.00
R7667:Ros1 UTSW 10 52,040,067 (GRCm39) missense probably damaging 1.00
R7696:Ros1 UTSW 10 52,018,379 (GRCm39) missense probably damaging 1.00
R7785:Ros1 UTSW 10 52,038,944 (GRCm39) missense probably damaging 1.00
R7814:Ros1 UTSW 10 51,972,233 (GRCm39) missense probably benign 0.28
R7830:Ros1 UTSW 10 52,031,030 (GRCm39) missense probably damaging 0.99
R7832:Ros1 UTSW 10 52,020,957 (GRCm39) missense probably damaging 0.99
R7854:Ros1 UTSW 10 52,004,563 (GRCm39) missense probably damaging 1.00
R7912:Ros1 UTSW 10 52,044,791 (GRCm39) missense probably damaging 1.00
R7972:Ros1 UTSW 10 52,030,926 (GRCm39) nonsense probably null
R7993:Ros1 UTSW 10 51,999,443 (GRCm39) missense probably benign 0.34
R8036:Ros1 UTSW 10 52,041,439 (GRCm39) missense probably benign
R8137:Ros1 UTSW 10 52,001,933 (GRCm39) missense possibly damaging 0.87
R8169:Ros1 UTSW 10 51,940,768 (GRCm39) critical splice donor site probably null
R8199:Ros1 UTSW 10 51,977,813 (GRCm39) nonsense probably null
R8293:Ros1 UTSW 10 51,964,014 (GRCm39) missense probably damaging 1.00
R8368:Ros1 UTSW 10 51,940,833 (GRCm39) missense probably damaging 1.00
R8406:Ros1 UTSW 10 51,977,941 (GRCm39) missense possibly damaging 0.56
R8471:Ros1 UTSW 10 51,997,078 (GRCm39) missense probably benign 0.00
R8498:Ros1 UTSW 10 52,055,047 (GRCm39) missense probably damaging 0.99
R8532:Ros1 UTSW 10 51,974,852 (GRCm39) missense possibly damaging 0.92
R8678:Ros1 UTSW 10 51,963,998 (GRCm39) missense probably benign
R8726:Ros1 UTSW 10 51,954,769 (GRCm39) missense possibly damaging 0.46
R8789:Ros1 UTSW 10 51,999,328 (GRCm39) missense probably damaging 0.99
R8799:Ros1 UTSW 10 51,922,143 (GRCm39) missense probably benign 0.08
R8915:Ros1 UTSW 10 51,977,805 (GRCm39) splice site probably benign
R8958:Ros1 UTSW 10 51,972,190 (GRCm39) missense probably damaging 1.00
R8972:Ros1 UTSW 10 51,999,333 (GRCm39) missense probably benign 0.05
R9020:Ros1 UTSW 10 52,031,023 (GRCm39) missense probably benign 0.32
R9147:Ros1 UTSW 10 51,927,039 (GRCm39) missense probably benign
R9154:Ros1 UTSW 10 51,922,301 (GRCm39) missense possibly damaging 0.87
R9189:Ros1 UTSW 10 52,019,502 (GRCm39) missense probably damaging 0.99
R9341:Ros1 UTSW 10 51,972,116 (GRCm39) critical splice donor site probably null
R9343:Ros1 UTSW 10 51,972,116 (GRCm39) critical splice donor site probably null
R9407:Ros1 UTSW 10 51,994,491 (GRCm39) missense probably damaging 1.00
R9428:Ros1 UTSW 10 51,958,061 (GRCm39) missense probably benign 0.00
R9502:Ros1 UTSW 10 52,000,174 (GRCm39) missense probably benign 0.00
R9531:Ros1 UTSW 10 52,007,063 (GRCm39) missense probably damaging 1.00
R9546:Ros1 UTSW 10 51,994,215 (GRCm39) critical splice donor site probably null
R9562:Ros1 UTSW 10 51,943,170 (GRCm39) missense probably damaging 1.00
R9565:Ros1 UTSW 10 51,943,170 (GRCm39) missense probably damaging 1.00
R9604:Ros1 UTSW 10 51,994,249 (GRCm39) missense probably damaging 1.00
R9645:Ros1 UTSW 10 51,948,148 (GRCm39) critical splice donor site probably null
R9658:Ros1 UTSW 10 51,967,069 (GRCm39) missense probably damaging 0.99
R9664:Ros1 UTSW 10 51,996,931 (GRCm39) missense probably benign 0.18
RF018:Ros1 UTSW 10 52,031,217 (GRCm39) missense probably benign
Z1176:Ros1 UTSW 10 51,967,205 (GRCm39) missense possibly damaging 0.89
Z1177:Ros1 UTSW 10 52,044,767 (GRCm39) missense probably damaging 0.99
Posted On 2013-10-07