Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01353:Vmn1r223'

75432

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r223

Ensembl Gene

ENSMUSG00000069280

Gene Name

vomeronasal 1 receptor 223

Synonyms

Gm11330

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.054) question?

Stock #

IGL01353

Quality Score

Status

Chromosome

Chromosomal Location

23433408-23434493 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 23433426 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 7 (T7A)

Ref Sequence

ENSEMBL: ENSMUSP00000089312 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000091719]

AlphaFold

Q5SSA0

Predicted Effect

unknown
Transcript: ENSMUST00000091719
AA Change: T7A

SMART Domains

Protein: ENSMUSP00000089312
Gene: ENSMUSG00000069280
AA Change: T7A

Domain	Start	End	E-Value	Type
low complexity region	46	59	N/A	INTRINSIC
Pfam:TAS2R	63	355	6.6e-10	PFAM
Pfam:V1R	94	357	2.1e-39	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 42 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc3	A	T	11: 94,242,934 (GRCm39)	V1304E	possibly damaging	Het
Acr	T	C	15: 89,453,695 (GRCm39)	L78P	probably damaging	Het
Adamts12	T	C	15: 11,292,091 (GRCm39)		probably benign	Het
Adgrb2	T	C	4: 129,906,093 (GRCm39)	S872P	probably damaging	Het
Adhfe1	T	A	1: 9,637,088 (GRCm39)	N413K	probably benign	Het
Apoh	T	A	11: 108,288,211 (GRCm39)	C110S	probably damaging	Het
Arhgap11a	A	G	2: 113,663,869 (GRCm39)	F805L	probably damaging	Het
Bin3	C	T	14: 70,372,275 (GRCm39)	L191F	possibly damaging	Het
Col3a1	A	G	1: 45,372,798 (GRCm39)		probably benign	Het
Dapp1	T	C	3: 137,667,241 (GRCm39)	K107R	probably benign	Het
Dnah5	T	C	15: 28,233,418 (GRCm39)	V259A	probably benign	Het
Dnah6	T	C	6: 73,150,439 (GRCm39)	M775V	probably benign	Het
Dnah9	A	G	11: 65,971,397 (GRCm39)	L1597P	probably damaging	Het
Elfn2	G	A	15: 78,556,618 (GRCm39)	A643V	possibly damaging	Het
Epha6	T	C	16: 60,245,258 (GRCm39)	T314A	probably damaging	Het
Fn1	C	A	1: 71,626,098 (GRCm39)	W2237L	probably damaging	Het
Foxp4	T	A	17: 48,199,078 (GRCm39)	D97V	probably damaging	Het
Kcnb2	C	A	1: 15,781,048 (GRCm39)	T640K	probably benign	Het
Lypd10	G	T	7: 24,413,662 (GRCm39)	S226I	probably damaging	Het
Miga2	G	A	2: 30,261,245 (GRCm39)		probably null	Het
Nacad	T	A	11: 6,550,530 (GRCm39)	Q887L	possibly damaging	Het
Or2m13	C	T	16: 19,226,333 (GRCm39)	M145I	probably benign	Het
Or4d1	T	C	11: 87,804,998 (GRCm39)	I245V	probably benign	Het
Or7e173	T	C	9: 19,938,343 (GRCm39)	N297S	probably damaging	Het
Or8k24	A	T	2: 86,216,365 (GRCm39)	Y132*	probably null	Het
Otub2	A	T	12: 103,370,581 (GRCm39)	M288L	probably benign	Het
Otud4	A	G	8: 80,391,650 (GRCm39)	S432G	probably benign	Het
Pcca	G	A	14: 122,820,029 (GRCm39)	V58I	probably damaging	Het
Pdpr	T	A	8: 111,847,910 (GRCm39)		probably null	Het
Pinx1	C	A	14: 64,103,564 (GRCm39)	Q48K	probably benign	Het
Pkd1l2	G	T	8: 117,784,182 (GRCm39)	S698R	probably benign	Het
Psg29	A	G	7: 16,938,938 (GRCm39)	R71G	possibly damaging	Het
Psmd3	T	A	11: 98,581,426 (GRCm39)	V271E	probably benign	Het
Smarcc1	A	G	9: 109,964,734 (GRCm39)	N97S	probably benign	Het
Sulf2	C	T	2: 165,929,015 (GRCm39)	G319S	probably damaging	Het
Tmem67	C	A	4: 12,079,895 (GRCm39)	C132F	probably damaging	Het
Ttll7	T	C	3: 146,667,474 (GRCm39)	L780P	probably damaging	Het
Vmn1r76	T	G	7: 11,664,737 (GRCm39)	H159P	probably damaging	Het
Vnn1	G	A	10: 23,776,738 (GRCm39)	C363Y	probably damaging	Het
Wdr64	T	G	1: 175,559,151 (GRCm39)	L305V	probably damaging	Het
Zkscan4	T	C	13: 21,668,518 (GRCm39)	L323P	probably damaging	Het
Zscan10	A	T	17: 23,828,574 (GRCm39)	H295L	probably damaging	Het

Other mutations in Vmn1r223

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00661:Vmn1r223	APN	13	23,434,254 (GRCm39)	missense	probably damaging	1.00
IGL01016:Vmn1r223	APN	13	23,434,237 (GRCm39)	missense	probably damaging	1.00
IGL01941:Vmn1r223	APN	13	23,434,407 (GRCm39)	missense	possibly damaging	0.94
IGL02976:Vmn1r223	APN	13	23,434,165 (GRCm39)	missense	probably damaging	1.00
IGL03064:Vmn1r223	APN	13	23,434,153 (GRCm39)	missense	probably damaging	1.00
IGL03136:Vmn1r223	APN	13	23,433,933 (GRCm39)	missense	possibly damaging	0.81
PIT4812001:Vmn1r223	UTSW	13	23,434,060 (GRCm39)	missense	probably damaging	0.99
R1468:Vmn1r223	UTSW	13	23,434,038 (GRCm39)	missense	possibly damaging	0.81
R1468:Vmn1r223	UTSW	13	23,434,038 (GRCm39)	missense	possibly damaging	0.81
R1592:Vmn1r223	UTSW	13	23,433,837 (GRCm39)	missense	possibly damaging	0.57
R1640:Vmn1r223	UTSW	13	23,434,348 (GRCm39)	missense	probably damaging	1.00
R2116:Vmn1r223	UTSW	13	23,433,832 (GRCm39)	missense	probably damaging	1.00
R3076:Vmn1r223	UTSW	13	23,434,335 (GRCm39)	missense	probably benign	0.15
R4229:Vmn1r223	UTSW	13	23,433,585 (GRCm39)	missense	probably benign	0.08
R4230:Vmn1r223	UTSW	13	23,433,585 (GRCm39)	missense	probably benign	0.08
R5420:Vmn1r223	UTSW	13	23,433,675 (GRCm39)	missense	probably benign	0.02
R6412:Vmn1r223	UTSW	13	23,433,825 (GRCm39)	missense	probably benign	0.05
R6424:Vmn1r223	UTSW	13	23,434,345 (GRCm39)	missense	probably damaging	1.00
R6607:Vmn1r223	UTSW	13	23,433,919 (GRCm39)	missense	probably damaging	1.00
R6944:Vmn1r223	UTSW	13	23,433,483 (GRCm39)	missense	unknown
R7256:Vmn1r223	UTSW	13	23,434,036 (GRCm39)	missense	probably damaging	1.00
R8241:Vmn1r223	UTSW	13	23,433,982 (GRCm39)	missense	probably benign	0.38
R8315:Vmn1r223	UTSW	13	23,434,339 (GRCm39)	missense	probably damaging	1.00
R8347:Vmn1r223	UTSW	13	23,434,020 (GRCm39)	missense	probably damaging	1.00
R8975:Vmn1r223	UTSW	13	23,434,248 (GRCm39)	missense	possibly damaging	0.84
R9075:Vmn1r223	UTSW	13	23,433,600 (GRCm39)	missense	possibly damaging	0.50

Posted On

2013-10-07