Incidental Mutation 'IGL01354:Gm11437'
ID75485
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm11437
Ensembl Gene ENSMUSG00000051452
Gene Namepredicted gene 11437
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.106) question?
Stock #IGL01354
Quality Score
Status
Chromosome11
Chromosomal Location84148351-84167476 bp(-) (GRCm38)
Type of Mutationintron
DNA Base Change (assembly) T to A at 84167318 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000116174 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000050771] [ENSMUST00000133811]
Predicted Effect probably benign
Transcript: ENSMUST00000050771
SMART Domains Protein: ENSMUSP00000056084
Gene: ENSMUSG00000051452

DomainStartEndE-ValueType
Pfam:DUF4711 1 226 7.4e-102 PFAM
low complexity region 227 238 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000133811
SMART Domains Protein: ENSMUSP00000116174
Gene: ENSMUSG00000020532

DomainStartEndE-ValueType
signal peptide 1 22 N/A INTRINSIC
PDB:2YL2|B 115 157 2e-21 PDB
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aldh1l2 A G 10: 83,527,376 L41P probably damaging Het
Baz2b T C 2: 59,968,889 Q297R probably benign Het
Chl1 A T 6: 103,665,853 Q184L probably benign Het
Cyp2a5 A G 7: 26,837,103 D169G possibly damaging Het
Cyp2d34 G A 15: 82,617,622 T229M probably benign Het
Fgd5 C T 6: 92,061,843 R995* probably null Het
Gaa T C 11: 119,270,568 S146P probably benign Het
Gm6614 T C 6: 141,990,408 N317S probably benign Het
Inpp5a T C 7: 139,538,234 F235L probably damaging Het
Lpp T A 16: 24,762,066 Y177* probably null Het
Malt1 A G 18: 65,475,191 Y654C probably damaging Het
Olfr1302 A C 2: 111,780,901 N194H possibly damaging Het
Olfr1380 T C 11: 49,564,197 I92T probably damaging Het
Olfr878 G A 9: 37,919,544 V301I possibly damaging Het
Otog A G 7: 46,289,726 N2060S probably damaging Het
Phc1 G A 6: 122,334,083 T98I probably damaging Het
Pik3cb A G 9: 99,064,168 I535T possibly damaging Het
Plxna2 A G 1: 194,762,435 I712V probably benign Het
Psmc2 A G 5: 21,795,836 E103G possibly damaging Het
Ptprb A G 10: 116,343,891 I1405V probably benign Het
Ralgapa1 T C 12: 55,777,316 N260D possibly damaging Het
Reln G A 5: 21,919,175 Q2778* probably null Het
Sptlc1 T A 13: 53,333,951 Q452L probably benign Het
Traf4 C A 11: 78,165,400 R14L possibly damaging Het
Ubap2 T C 4: 41,207,005 E191G probably damaging Het
Vstm4 A T 14: 32,919,245 T262S probably benign Het
Zrsr1 T A 11: 22,974,190 H321Q probably damaging Het
Other mutations in Gm11437
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00959:Gm11437 APN 11 84148622 intron probably benign
IGL02051:Gm11437 APN 11 84152766 missense probably benign 0.00
IGL03184:Gm11437 APN 11 84156264 intron probably benign
R0076:Gm11437 UTSW 11 84148636 missense possibly damaging 0.91
R0076:Gm11437 UTSW 11 84148636 missense possibly damaging 0.91
R1241:Gm11437 UTSW 11 84164628 missense possibly damaging 0.93
R2135:Gm11437 UTSW 11 84153812 missense probably damaging 0.97
R4065:Gm11437 UTSW 11 84164511 missense probably benign 0.13
R4067:Gm11437 UTSW 11 84164511 missense probably benign 0.13
R5356:Gm11437 UTSW 11 84152687 missense possibly damaging 0.90
R6571:Gm11437 UTSW 11 84156212 missense probably benign 0.13
R6594:Gm11437 UTSW 11 84164560 missense probably null 0.03
R7173:Gm11437 UTSW 11 84164548 missense probably benign 0.39
R7368:Gm11437 UTSW 11 84167472 intron probably benign
X0026:Gm11437 UTSW 11 84165327 missense possibly damaging 0.92
X0028:Gm11437 UTSW 11 84156100 critical splice donor site probably null
Posted On2013-10-07