Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01359:Lce1f'

75655

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Lce1f

Ensembl Gene

ENSMUSG00000042124

Gene Name

late cornified envelope 1F

Synonyms

1110055J05Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.108) question?

Stock #

IGL01359

Quality Score

Status

Chromosome

Chromosomal Location

92626003-92627657 bp(-) (GRCm39)

Type of Mutation

nonsense

DNA Base Change (assembly)

G to T at 92626491 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Stop codon at position 55 (C55*)

Ref Sequence

ENSEMBL: ENSMUSP00000037349 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000047153]

AlphaFold

B9EJP6

Predicted Effect

probably null
Transcript: ENSMUST00000047153
AA Change: C55*

SMART Domains

Protein: ENSMUSP00000037349
Gene: ENSMUSG00000042124
AA Change: C55*

Domain	Start	End	E-Value	Type
Pfam:LCE	25	66	3.3e-13	PFAM
Pfam:LCE	64	124	3.6e-12	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 47 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgrf1	G	A	17: 43,621,577 (GRCm39)	E605K	probably damaging	Het
Adgrl4	G	A	3: 151,248,923 (GRCm39)	C737Y	probably damaging	Het
Ankk1	A	T	9: 49,327,328 (GRCm39)	I617N	possibly damaging	Het
B3gat2	T	C	1: 23,802,301 (GRCm39)	F196L	probably damaging	Het
Bcl2l14	T	A	6: 134,400,828 (GRCm39)	I83N	probably damaging	Het
Bcr	T	C	10: 74,995,611 (GRCm39)		probably benign	Het
Ckmt2	A	T	13: 92,009,939 (GRCm39)	I127N	probably damaging	Het
Dhx33	G	A	11: 70,884,687 (GRCm39)	Q40*	probably null	Het
Dnah11	T	C	12: 117,946,734 (GRCm39)	T3117A	probably damaging	Het
Dnai2	A	G	11: 114,642,614 (GRCm39)	Y405C	probably benign	Het
Emc2	A	G	15: 43,375,145 (GRCm39)	Y214C	probably damaging	Het
Fbxw2	T	C	2: 34,712,762 (GRCm39)	T100A	probably benign	Het
Fkrp	C	T	7: 16,545,415 (GRCm39)	R149Q	probably benign	Het
Fsd1l	A	G	4: 53,659,601 (GRCm39)	R153G	possibly damaging	Het
Galnt4	T	C	10: 98,945,459 (GRCm39)	Y395H	probably damaging	Het
Gk5	T	C	9: 96,019,842 (GRCm39)	L126P	probably damaging	Het
Gm973	A	G	1: 59,669,438 (GRCm39)	S830G	probably benign	Het
Gpc5	G	A	14: 115,607,162 (GRCm39)	G255S	possibly damaging	Het
Grk3	C	A	5: 113,085,626 (GRCm39)	S370I	probably damaging	Het
Herc1	A	G	9: 66,346,550 (GRCm39)	D1972G	probably benign	Het
Itih3	T	A	14: 30,639,729 (GRCm39)	D364V	probably damaging	Het
Ltn1	A	C	16: 87,202,581 (GRCm39)		probably benign	Het
Lyl1	C	T	8: 85,429,315 (GRCm39)	A8V	possibly damaging	Het
Mdn1	A	G	4: 32,743,686 (GRCm39)	E3974G	probably benign	Het
Msl3l2	T	C	10: 55,992,340 (GRCm39)	V355A	probably damaging	Het
Nadsyn1	T	C	7: 143,374,967 (GRCm39)	I30V	possibly damaging	Het
Nuggc	T	C	14: 65,860,656 (GRCm39)	V418A	probably damaging	Het
Or4f57	A	T	2: 111,791,406 (GRCm39)	M4K	probably benign	Het
Or52e8	T	C	7: 104,625,193 (GRCm39)		probably null	Het
Or52m2	A	T	7: 102,263,379 (GRCm39)	H272Q	probably benign	Het
Ppp4r3a	T	C	12: 101,024,755 (GRCm39)	E248G	probably damaging	Het
Rab3gap2	T	A	1: 184,971,067 (GRCm39)	V234E	probably damaging	Het
Radil	G	A	5: 142,529,468 (GRCm39)	T105I	probably damaging	Het
Saa4	A	G	7: 46,381,060 (GRCm39)	W21R	possibly damaging	Het
Sec62	G	A	3: 30,868,455 (GRCm39)	S228N	unknown	Het
Setd4	C	T	16: 93,388,127 (GRCm39)	G120S	probably damaging	Het
Sgpl1	G	A	10: 60,936,687 (GRCm39)	T556I	probably benign	Het
Slc14a2	T	C	18: 78,197,323 (GRCm39)	D811G	probably benign	Het
Slc26a11	A	T	11: 119,254,257 (GRCm39)	M192L	probably benign	Het
Spon1	A	T	7: 113,633,525 (GRCm39)	Q656L	probably damaging	Het
Tex15	A	G	8: 34,071,926 (GRCm39)	D2491G	probably damaging	Het
Tox	T	C	4: 6,697,583 (GRCm39)	T407A	probably damaging	Het
Ubr5	A	T	15: 37,973,250 (GRCm39)	I2611N	probably damaging	Het
Usp25	G	A	16: 76,856,141 (GRCm39)	A245T	probably damaging	Het
Vwa8	C	A	14: 79,302,353 (GRCm39)	Y1007*	probably null	Het
Zfp423	T	C	8: 88,507,290 (GRCm39)	H893R	probably damaging	Het
Zfp507	A	G	7: 35,493,927 (GRCm39)	I372T	probably damaging	Het

Other mutations in Lce1f

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL01884:Lce1f	APN	3	92,626,608 (GRCm39)	nonsense	probably null
R1499:Lce1f	UTSW	3	92,626,276 (GRCm39)	missense	unknown
R5728:Lce1f	UTSW	3	92,626,652 (GRCm39)	missense	unknown
R8285:Lce1f	UTSW	3	92,626,238 (GRCm39)	missense	unknown
R9356:Lce1f	UTSW	3	92,626,272 (GRCm39)	small deletion	probably benign
Z1088:Lce1f	UTSW	3	92,626,561 (GRCm39)	missense	unknown
Z1177:Lce1f	UTSW	3	92,626,505 (GRCm39)	missense	unknown

Posted On

2013-10-07