Incidental Mutation 'IGL01366:Dcpp1'
ID75930
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Dcpp1
Ensembl Gene ENSMUSG00000096445
Gene Namedemilune cell and parotid protein 1
Synonymsp20, Dcpp
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.139) question?
Stock #IGL01366
Quality Score
Status
Chromosome17
Chromosomal Location23880876-23882853 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 23882736 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Asparagine at position 153 (I153N)
Ref Sequence ENSEMBL: ENSMUSP00000064663 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000068580] [ENSMUST00000168272]
Predicted Effect possibly damaging
Transcript: ENSMUST00000068580
AA Change: I153N

PolyPhen 2 Score 0.900 (Sensitivity: 0.82; Specificity: 0.94)
SMART Domains Protein: ENSMUSP00000064663
Gene: ENSMUSG00000096445
AA Change: I153N

DomainStartEndE-ValueType
signal peptide 1 23 N/A INTRINSIC
Jacalin 32 159 5.49e-2 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000168272
SMART Domains Protein: ENSMUSP00000126379
Gene: ENSMUSG00000096278

DomainStartEndE-ValueType
signal peptide 1 23 N/A INTRINSIC
Jacalin 32 159 2.91e-1 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 36 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2310002L09Rik A T 4: 73,950,700 probably benign Het
Adamts2 T C 11: 50,796,468 Y1041H probably damaging Het
Adck5 A C 15: 76,595,616 *568C probably null Het
AK157302 T A 13: 21,495,301 probably benign Het
Bmpr2 G T 1: 59,813,677 G56W probably damaging Het
Capn11 A C 17: 45,653,200 I146S probably damaging Het
Ccdc162 A T 10: 41,580,306 D1613E possibly damaging Het
Ccdc167 T C 17: 29,705,312 E50G probably damaging Het
Col5a2 G T 1: 45,391,888 P864Q possibly damaging Het
Col7a1 C T 9: 108,977,119 probably benign Het
Crebbp T A 16: 4,126,506 H556L probably damaging Het
Dgke C T 11: 89,055,386 R196H probably benign Het
Efr3a T A 15: 65,851,150 I459K probably benign Het
Espl1 T A 15: 102,319,836 C1682S probably benign Het
Exosc3 C T 4: 45,317,747 R185H probably damaging Het
Fam160b2 G A 14: 70,585,373 R688C probably damaging Het
Fgd6 T C 10: 94,043,476 V64A possibly damaging Het
Gata3 A G 2: 9,877,465 L42P probably damaging Het
Ggta1 C A 2: 35,402,450 E282* probably null Het
Ghr T C 15: 3,320,187 D503G probably damaging Het
Gls C T 1: 52,168,399 G602D probably damaging Het
Gm2058 A G 7: 39,589,234 noncoding transcript Het
Grb7 T C 11: 98,452,274 probably benign Het
Ifngr1 A T 10: 19,609,600 H449L probably damaging Het
Ighg2b T G 12: 113,307,036 D158A possibly damaging Het
Nphs2 T C 1: 156,311,035 V83A probably benign Het
Parp6 T A 9: 59,636,713 M390K possibly damaging Het
Pask T C 1: 93,310,852 K1304E probably benign Het
Scai A G 2: 39,106,961 S274P probably benign Het
Sik2 A G 9: 50,907,463 S404P probably damaging Het
Slc7a8 A T 14: 54,781,188 I47N probably damaging Het
Tas2r113 A T 6: 132,893,797 I263F probably benign Het
Tdrd1 T A 19: 56,855,302 D737E probably benign Het
Trio T C 15: 27,732,868 T2976A possibly damaging Het
Ttc28 T C 5: 111,085,171 probably null Het
Vmn1r21 A G 6: 57,843,814 I215T probably benign Het
Other mutations in Dcpp1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02151:Dcpp1 APN 17 23882594 missense possibly damaging 0.46
FR4589:Dcpp1 UTSW 17 23881454 missense probably benign
R0505:Dcpp1 UTSW 17 23882594 missense possibly damaging 0.46
R1160:Dcpp1 UTSW 17 23881431 missense possibly damaging 0.95
R2096:Dcpp1 UTSW 17 23880997 critical splice acceptor site probably null
R7502:Dcpp1 UTSW 17 23882641 nonsense probably null
Posted On2013-10-07