Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01367:Clec2g'

75962

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Clec2g

Ensembl Gene

ENSMUSG00000000248

Gene Name

C-type lectin domain family 2, member g

Synonyms

Ocilrp1, 4632413B12Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.098) question?

Stock #

IGL01367

Quality Score

Status

Chromosome

Chromosomal Location

128911344-128961670 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 128925699 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Threonine at position 36 (I36T)

Ref Sequence

ENSEMBL: ENSMUSP00000000254 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000000254]

AlphaFold

Q9D676

Predicted Effect

unknown
Transcript: ENSMUST00000000254
AA Change: I36T

SMART Domains

Protein: ENSMUSP00000000254
Gene: ENSMUSG00000000248
AA Change: I36T

Domain	Start	End	E-Value	Type
Pfam:Lectin_C	3	108	2.4e-6	PFAM
low complexity region	114	126	N/A	INTRINSIC
CLECT	143	254	9.36e-25	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000141700

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000146925

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 44 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930505A04Rik	A	G	11: 30,404,843 (GRCm39)	V20A	possibly damaging	Het
Alk	T	C	17: 72,207,781 (GRCm39)	I985V	probably damaging	Het
Anapc2	A	C	2: 25,164,794 (GRCm39)	R59S	possibly damaging	Het
Ankhd1	T	A	18: 36,711,696 (GRCm39)	D165E	probably benign	Het
Asb8	A	T	15: 98,034,054 (GRCm39)	V167D	probably damaging	Het
Atp5pf	A	G	16: 84,625,360 (GRCm39)	M81T	probably benign	Het
Bcl7b	A	G	5: 135,208,950 (GRCm39)	T138A	probably damaging	Het
Cdh23	A	G	10: 60,146,566 (GRCm39)	L2869P	probably damaging	Het
Chl1	T	C	6: 103,706,186 (GRCm39)	S1174P	probably benign	Het
Denr	A	G	5: 124,046,182 (GRCm39)	D4G	probably benign	Het
Dnajc10	T	C	2: 80,155,096 (GRCm39)		probably benign	Het
Egf	C	T	3: 129,496,104 (GRCm39)		probably null	Het
Galnt10	A	C	11: 57,616,409 (GRCm39)	Y108S	probably damaging	Het
Gls	C	T	1: 52,207,558 (GRCm39)	G602D	probably damaging	Het
Grb10	G	T	11: 11,895,599 (GRCm39)	Q242K	probably damaging	Het
Hspg2	A	T	4: 137,265,800 (GRCm39)	Y1837F	probably damaging	Het
Ikzf1	G	T	11: 11,698,358 (GRCm39)	A70S	probably benign	Het
Il17ra	T	C	6: 120,458,426 (GRCm39)	Y526H	probably damaging	Het
Il34	A	T	8: 111,469,375 (GRCm39)	I186N	possibly damaging	Het
Iqca1	G	A	1: 89,998,350 (GRCm39)		probably benign	Het
Kntc1	A	G	5: 123,896,546 (GRCm39)	Y136C	probably damaging	Het
Man2b2	A	T	5: 36,971,681 (GRCm39)	Y257*	probably null	Het
Map3k19	A	G	1: 127,752,088 (GRCm39)	F421S	possibly damaging	Het
Melk	A	G	4: 44,332,907 (GRCm39)	T288A	possibly damaging	Het
Mpp2	T	C	11: 101,954,135 (GRCm39)	E187G	probably damaging	Het
Mtf2	A	G	5: 108,252,323 (GRCm39)	T394A	probably benign	Het
Neil2	A	G	14: 63,429,177 (GRCm39)	S39P	probably damaging	Het
Or4e5	T	A	14: 52,727,624 (GRCm39)	I266F	probably benign	Het
Pcdh7	A	G	5: 58,286,566 (GRCm39)	E1214G	possibly damaging	Het
Pcdhb17	G	T	18: 37,620,548 (GRCm39)	Q779H	probably benign	Het
Pik3c2b	A	G	1: 133,033,726 (GRCm39)	I1577V	probably benign	Het
Pkp3	C	T	7: 140,663,989 (GRCm39)	P389S	probably damaging	Het
Ppp4r2	T	A	6: 100,841,706 (GRCm39)	Y92*	probably null	Het
Rnf13	T	C	3: 57,714,508 (GRCm39)	I189T	probably benign	Het
Serpinf2	T	C	11: 75,328,871 (GRCm39)	D53G	probably benign	Het
Slc47a2	T	A	11: 61,220,607 (GRCm39)	T184S	probably benign	Het
Sned1	T	C	1: 93,210,936 (GRCm39)	I1008T	probably benign	Het
Sorcs3	A	T	19: 48,784,814 (GRCm39)	E1079V	probably damaging	Het
Trappc8	G	A	18: 20,999,176 (GRCm39)	S318L	probably benign	Het
Trappc9	A	G	15: 72,462,002 (GRCm39)	S909P	probably benign	Het
Ttn	G	A	2: 76,560,483 (GRCm39)	T29306I	probably damaging	Het
Twnk	G	A	19: 45,000,090 (GRCm39)	R602Q	possibly damaging	Het
Vmn2r15	A	T	5: 109,441,075 (GRCm39)	I261K	probably damaging	Het
Vmn2r77	G	A	7: 86,461,124 (GRCm39)	A817T	probably damaging	Het

Other mutations in Clec2g

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00825:Clec2g	APN	6	128,957,144 (GRCm39)	splice site	probably null
IGL00901:Clec2g	APN	6	128,925,655 (GRCm39)	splice site	probably benign
IGL01514:Clec2g	APN	6	128,925,736 (GRCm39)	missense	probably benign	0.02
IGL02742:Clec2g	APN	6	128,957,224 (GRCm39)	missense	possibly damaging	0.95
R0069:Clec2g	UTSW	6	128,957,274 (GRCm39)	critical splice donor site	probably null
R0069:Clec2g	UTSW	6	128,925,716 (GRCm39)	missense	probably benign	0.02
R0368:Clec2g	UTSW	6	128,957,224 (GRCm39)	missense	possibly damaging	0.95
R1809:Clec2g	UTSW	6	128,957,273 (GRCm39)	critical splice donor site	probably null
R1813:Clec2g	UTSW	6	128,925,660 (GRCm39)	missense	unknown
R2866:Clec2g	UTSW	6	128,925,719 (GRCm39)	missense	probably benign
R4080:Clec2g	UTSW	6	128,958,287 (GRCm39)	missense	probably damaging	0.96
R4732:Clec2g	UTSW	6	128,958,842 (GRCm39)	nonsense	probably null
R4733:Clec2g	UTSW	6	128,958,842 (GRCm39)	nonsense	probably null
R4906:Clec2g	UTSW	6	128,956,411 (GRCm39)	missense	probably benign
R5014:Clec2g	UTSW	6	128,925,765 (GRCm39)	missense	probably benign	0.00
R5220:Clec2g	UTSW	6	128,958,269 (GRCm39)	missense	probably benign	0.00
R5342:Clec2g	UTSW	6	128,925,714 (GRCm39)	missense	probably benign	0.04
R6155:Clec2g	UTSW	6	128,957,236 (GRCm39)	missense	probably damaging	1.00
R6353:Clec2g	UTSW	6	128,959,895 (GRCm39)	splice site	probably null
R6372:Clec2g	UTSW	6	128,925,726 (GRCm39)	missense	probably benign	0.00
R7678:Clec2g	UTSW	6	128,956,400 (GRCm39)	missense	probably damaging	0.96
R7821:Clec2g	UTSW	6	128,925,740 (GRCm39)	missense	probably benign	0.00
R8252:Clec2g	UTSW	6	128,958,335 (GRCm39)	missense	probably benign	0.09
R8909:Clec2g	UTSW	6	128,958,195 (GRCm39)	missense	probably benign	0.09
R9010:Clec2g	UTSW	6	128,925,688 (GRCm39)	missense	unknown
R9781:Clec2g	UTSW	6	128,960,012 (GRCm39)	missense	probably benign	0.03

Posted On

2013-10-07