Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01368:Eif1ad15'

76005

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Eif1ad15

Ensembl Gene

ENSMUSG00000093847

Gene Name

eukaryotic translation initiation factor 1A domain containing 15

Synonyms

Gm5039

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.411) question?

Stock #

IGL01368

Quality Score

Status

Chromosome

Chromosomal Location

88286892-88288532 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 88287858 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Asparagine at position 132 (D132N)

Ref Sequence

ENSEMBL: ENSMUSP00000151971 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000177747] [ENSMUST00000218054]

AlphaFold

J3QNT6

Predicted Effect

unknown
Transcript: ENSMUST00000177747
AA Change: D132N

SMART Domains

Protein: ENSMUSP00000136949
Gene: ENSMUSG00000093847
AA Change: D132N

Domain	Start	End	E-Value	Type
low complexity region	3	25	N/A	INTRINSIC
eIF1a	28	110	4.9e-47	SMART
low complexity region	125	144	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000218054
AA Change: D132N

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000222722

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 30 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acod1	T	A	14: 103,288,770 (GRCm39)	D93E	probably damaging	Het
Adam22	T	C	5: 8,177,411 (GRCm39)	Y566C	probably damaging	Het
Atp8b3	G	A	10: 80,370,063 (GRCm39)		probably benign	Het
Babam1	T	A	8: 71,851,050 (GRCm39)	D104E	probably damaging	Het
Bcl2a1a	T	A	9: 88,839,500 (GRCm39)	W133R	probably damaging	Het
Ckm	C	T	7: 19,150,712 (GRCm39)	Q184*	probably null	Het
Clk4	T	A	11: 51,171,999 (GRCm39)	Y246*	probably null	Het
Cyp3a57	T	C	5: 145,305,878 (GRCm39)	S121P	probably damaging	Het
Gm8011	T	C	14: 42,287,831 (GRCm39)		probably benign	Het
Gpr153	T	C	4: 152,367,451 (GRCm39)	F434S	probably benign	Het
Gpr158	G	T	2: 21,831,909 (GRCm39)	W1003L	probably damaging	Het
Ighv5-9-1	T	C	12: 113,700,010 (GRCm39)	E34G	probably damaging	Het
Igkv16-104	G	T	6: 68,402,594 (GRCm39)	R2S	possibly damaging	Het
Map3k3	T	C	11: 106,041,215 (GRCm39)	F395L	probably benign	Het
Myof	T	A	19: 37,924,905 (GRCm39)	T1161S	probably damaging	Het
Nlrp9a	T	C	7: 26,257,299 (GRCm39)	S217P	probably damaging	Het
Nol9	T	A	4: 152,142,848 (GRCm39)	N687K	probably benign	Het
Or10ad1	T	C	15: 98,105,381 (GRCm39)	I295V	probably damaging	Het
Or11h23	T	C	14: 50,948,450 (GRCm39)	V221A	possibly damaging	Het
Or2ag15	T	C	7: 106,340,829 (GRCm39)	E104G	probably benign	Het
Or8g33	A	T	9: 39,337,476 (GRCm39)	V297D	probably damaging	Het
Prss1l	A	G	6: 41,373,620 (GRCm39)	D161G	possibly damaging	Het
Rrh	T	C	3: 129,602,618 (GRCm39)	D229G	probably benign	Het
Sclt1	T	C	3: 41,665,610 (GRCm39)	T153A	probably damaging	Het
Slc41a1	G	A	1: 131,766,862 (GRCm39)	V127I	probably damaging	Het
Smarca2	C	T	19: 26,751,694 (GRCm39)	S214L	possibly damaging	Het
Tmem63a	T	C	1: 180,797,797 (GRCm39)	V616A	possibly damaging	Het
Ubr1	A	G	2: 120,771,612 (GRCm39)		probably benign	Het
Vmn1r228	A	G	17: 20,996,774 (GRCm39)	L248P	probably benign	Het
Zdhhc16	T	A	19: 41,929,945 (GRCm39)		probably null	Het

Other mutations in Eif1ad15

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02184:Eif1ad15	APN	12	88,287,951 (GRCm39)	missense	probably benign	0.13
R2029:Eif1ad15	UTSW	12	88,288,191 (GRCm39)	missense	unknown
R2943:Eif1ad15	UTSW	12	88,288,004 (GRCm39)	missense	probably benign	0.04
R5022:Eif1ad15	UTSW	12	88,288,071 (GRCm39)	missense	probably benign	0.08
R5054:Eif1ad15	UTSW	12	88,288,071 (GRCm39)	missense	probably benign	0.08
R5988:Eif1ad15	UTSW	12	88,288,202 (GRCm39)	missense	unknown
R6275:Eif1ad15	UTSW	12	88,287,995 (GRCm39)	missense	possibly damaging	0.95
R6596:Eif1ad15	UTSW	12	88,288,057 (GRCm39)	missense	possibly damaging	0.92
R6863:Eif1ad15	UTSW	12	88,287,968 (GRCm39)	missense	probably damaging	1.00
R8550:Eif1ad15	UTSW	12	88,290,652 (GRCm39)	start gained	probably benign
R8993:Eif1ad15	UTSW	12	88,288,170 (GRCm39)	missense	probably benign	0.01

Posted On

2013-10-07