Incidental Mutation 'IGL01368:Gm5771'
ID 76028
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm5771
Ensembl Gene ENSMUSG00000058119
Gene Name predicted gene 5771
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.075) question?
Stock # IGL01368
Quality Score
Status
Chromosome 6
Chromosomal Location 41392356-41397230 bp(+) (GRCm38)
Type of Mutation missense
DNA Base Change (assembly) A to G at 41396686 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Aspartic acid to Glycine at position 161 (D161G)
Ref Sequence ENSEMBL: ENSMUSP00000039684 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000049079]
AlphaFold Q792Y9
Predicted Effect possibly damaging
Transcript: ENSMUST00000049079
AA Change: D161G

PolyPhen 2 Score 0.938 (Sensitivity: 0.80; Specificity: 0.94)
SMART Domains Protein: ENSMUSP00000039684
Gene: ENSMUSG00000058119
AA Change: D161G

DomainStartEndE-ValueType
low complexity region 3 16 N/A INTRINSIC
Tryp_SPc 22 238 9.72e-105 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 30 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acod1 T A 14: 103,051,334 D93E probably damaging Het
Adam22 T C 5: 8,127,411 Y566C probably damaging Het
Atp8b3 G A 10: 80,534,229 probably benign Het
Babam1 T A 8: 71,398,406 D104E probably damaging Het
Bcl2a1a T A 9: 88,957,447 W133R probably damaging Het
Ckm C T 7: 19,416,787 Q184* probably null Het
Clk4 T A 11: 51,281,172 Y246* probably null Het
Cyp3a57 T C 5: 145,369,068 S121P probably damaging Het
Gm5039 C T 12: 88,321,088 D132N unknown Het
Gm8011 T C 14: 42,465,874 probably benign Het
Gpr153 T C 4: 152,282,994 F434S probably benign Het
Gpr158 G T 2: 21,827,098 W1003L probably damaging Het
Ighv5-9-1 T C 12: 113,736,390 E34G probably damaging Het
Igkv16-104 G T 6: 68,425,610 R2S possibly damaging Het
Map3k3 T C 11: 106,150,389 F395L probably benign Het
Myof T A 19: 37,936,457 T1161S probably damaging Het
Nlrp9a T C 7: 26,557,874 S217P probably damaging Het
Nol9 T A 4: 152,058,391 N687K probably benign Het
Olfr287 T C 15: 98,207,500 I295V probably damaging Het
Olfr697 T C 7: 106,741,622 E104G probably benign Het
Olfr748 T C 14: 50,710,993 V221A possibly damaging Het
Olfr952 A T 9: 39,426,180 V297D probably damaging Het
Rrh T C 3: 129,808,969 D229G probably benign Het
Sclt1 T C 3: 41,711,175 T153A probably damaging Het
Slc41a1 G A 1: 131,839,124 V127I probably damaging Het
Smarca2 C T 19: 26,774,294 S214L possibly damaging Het
Tmem63a T C 1: 180,970,232 V616A possibly damaging Het
Ubr1 A G 2: 120,941,131 probably benign Het
Vmn1r228 A G 17: 20,776,512 L248P probably benign Het
Zdhhc16 T A 19: 41,941,506 probably null Het
Other mutations in Gm5771
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00330:Gm5771 APN 6 41394773 missense probably damaging 1.00
IGL00586:Gm5771 APN 6 41396115 missense probably damaging 1.00
IGL01103:Gm5771 APN 6 41397157 missense probably damaging 1.00
IGL01458:Gm5771 APN 6 41396687 missense probably benign 0.01
IGL03114:Gm5771 APN 6 41397078 missense probably damaging 1.00
R0167:Gm5771 UTSW 6 41396261 splice site probably benign
R1548:Gm5771 UTSW 6 41396011 missense probably damaging 1.00
R4584:Gm5771 UTSW 6 41396767 missense probably benign 0.35
R5622:Gm5771 UTSW 6 41396150 missense probably damaging 1.00
R5664:Gm5771 UTSW 6 41394671 missense probably benign 0.04
R6222:Gm5771 UTSW 6 41397166 missense probably damaging 0.98
R6325:Gm5771 UTSW 6 41396656 missense probably benign 0.00
R7816:Gm5771 UTSW 6 41394773 missense probably damaging 1.00
R7986:Gm5771 UTSW 6 41396124 missense probably damaging 1.00
R8016:Gm5771 UTSW 6 41397166 missense probably damaging 0.98
Posted On 2013-10-07