Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01371:Dync1h1'

76148

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Dync1h1

Ensembl Gene

ENSMUSG00000018707

Gene Name

dynein cytoplasmic 1 heavy chain 1

Synonyms

MAP1C, Loa, Dnec1, Dnchc1, dynein heavy chain, retrograde transport, 9930018I23Rik, Swl

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

IGL01371

Quality Score

Status

Chromosome

Chromosomal Location

110567886-110633379 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 110605285 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Serine at position 2374 (N2374S)

Ref Sequence

ENSEMBL: ENSMUSP00000018851 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000018851]

AlphaFold

no structure available at present

PDB Structure

Microtubule binding domain from mouse cytoplasmic dynein as a fusion with seryl-tRNA synthetase [X-RAY DIFFRACTION]
High affinity dynein microtubule binding domain - tubulin complex [ELECTRON MICROSCOPY]
Low affinity dynein microtubule binding domain - tubulin complex [ELECTRON MICROSCOPY]
Structure of the entire stalk region of the dynein motor domain [X-RAY DIFFRACTION]

Predicted Effect

probably benign
Transcript: ENSMUST00000018851
AA Change: N2374S

PolyPhen 2 Score 0.047 (Sensitivity: 0.94; Specificity: 0.83)

SMART Domains

Protein: ENSMUSP00000018851
Gene: ENSMUSG00000018707
AA Change: N2374S

Domain	Start	End	E-Value	Type
low complexity region	46	61	N/A	INTRINSIC
low complexity region	83	95	N/A	INTRINSIC
Pfam:DHC_N1	237	830	1.9e-145	PFAM
coiled coil region	1171	1198	N/A	INTRINSIC
Pfam:DHC_N2	1317	1721	3.3e-116	PFAM
AAA	1899	2043	5.39e-2	SMART
low complexity region	2102	2116	N/A	INTRINSIC
AAA	2214	2365	2.13e0	SMART
low complexity region	2394	2405	N/A	INTRINSIC
AAA	2585	2735	8.6e-7	SMART
Blast:AAA	2777	2811	2e-13	BLAST
AAA	2927	3093	4.79e-5	SMART
Pfam:MT	3197	3534	1.1e-44	PFAM
Pfam:AAA_9	3554	3778	8.5e-75	PFAM
Pfam:Dynein_heavy	3919	4642	4.3e-163	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000172218

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family. [provided by RefSeq, Oct 2008]
PHENOTYPE: Mice homozygous for either the Cra1 or Loa ENU mutation exhibit neonatal lethality with reduced anterior horn cell number, abnormal motor neuron innervation, neuronal inclusions, and abnormal axonal transport. Heterozygotes display motor neuron degeneration and muscle spasms. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 31 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc9	C	T	6: 142,602,340 (GRCm39)	R691Q	probably benign	Het
Ambra1	G	T	2: 91,655,631 (GRCm39)	G700W	probably damaging	Het
Atp6v1c1	A	G	15: 38,683,204 (GRCm39)	I198V	probably benign	Het
Bptf	T	C	11: 106,946,733 (GRCm39)	N2353S	probably benign	Het
Cd84	A	T	1: 171,713,937 (GRCm39)	T312S	probably benign	Het
Chl1	G	T	6: 103,692,325 (GRCm39)	C1064F	probably damaging	Het
Clca4a	T	C	3: 144,666,433 (GRCm39)	D473G	probably damaging	Het
Dsp	A	G	13: 38,377,593 (GRCm39)	R1793G	probably benign	Het
Ecpas	A	G	4: 58,809,718 (GRCm39)	L1583P	probably damaging	Het
Gm43191	A	T	3: 116,439,112 (GRCm39)	I130N	probably damaging	Het
Gm5134	T	G	10: 75,840,581 (GRCm39)	L475R	probably damaging	Het
Grm1	A	G	10: 10,595,783 (GRCm39)	V615A	probably benign	Het
Inhca	T	C	9: 103,131,975 (GRCm39)	E504G	possibly damaging	Het
Loxl1	T	A	9: 58,201,705 (GRCm39)	Q462L	possibly damaging	Het
Nwd1	T	C	8: 73,401,743 (GRCm39)	W755R	probably damaging	Het
Or10j27	A	G	1: 172,958,098 (GRCm39)	S229P	possibly damaging	Het
Or5b106	G	A	19: 13,123,192 (GRCm39)	T277I	possibly damaging	Het
Or5t17	A	T	2: 86,833,267 (GRCm39)	K318M	probably benign	Het
Otud4	T	C	8: 80,400,390 (GRCm39)	F1034L	probably damaging	Het
Pakap	C	A	4: 57,856,325 (GRCm39)	D551E	probably benign	Het
Panx3	T	G	9: 37,572,771 (GRCm39)	T260P	probably benign	Het
Ppfia4	A	T	1: 134,255,824 (GRCm39)	S194T	probably benign	Het
Rnf135	T	A	11: 80,080,081 (GRCm39)	I124N	probably benign	Het
Rpf1	T	C	3: 146,213,302 (GRCm39)	N283S	probably damaging	Het
Smg5	A	G	3: 88,266,951 (GRCm39)		probably benign	Het
Stard9	A	G	2: 120,531,849 (GRCm39)	E2702G	probably benign	Het
Tbk1	A	T	10: 121,395,776 (GRCm39)	M439K	probably benign	Het
Tmem235	T	C	11: 117,753,132 (GRCm39)	L85P	possibly damaging	Het
Trhde	A	T	10: 114,424,405 (GRCm39)	V460E	possibly damaging	Het
Ttn	T	C	2: 76,620,608 (GRCm39)		probably benign	Het
Vmn1r83	A	G	7: 12,055,160 (GRCm39)	F299S	probably benign	Het

Other mutations in Dync1h1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01291:Dync1h1	APN	12	110,615,538 (GRCm39)	missense	probably benign	0.31
IGL01299:Dync1h1	APN	12	110,580,541 (GRCm39)	missense	probably benign	0.04
IGL01321:Dync1h1	APN	12	110,592,041 (GRCm39)	splice site	probably benign
IGL01324:Dync1h1	APN	12	110,593,299 (GRCm39)	missense	probably damaging	0.99
IGL01327:Dync1h1	APN	12	110,583,126 (GRCm39)	splice site	probably benign
IGL01598:Dync1h1	APN	12	110,624,562 (GRCm39)	missense	probably damaging	0.99
IGL01782:Dync1h1	APN	12	110,581,374 (GRCm39)	missense	probably damaging	1.00
IGL01791:Dync1h1	APN	12	110,625,364 (GRCm39)	missense	probably damaging	0.99
IGL01797:Dync1h1	APN	12	110,618,630 (GRCm39)	critical splice donor site	probably null
IGL02040:Dync1h1	APN	12	110,603,558 (GRCm39)	missense	probably benign	0.21
IGL02096:Dync1h1	APN	12	110,599,254 (GRCm39)	missense	possibly damaging	0.68
IGL02164:Dync1h1	APN	12	110,628,993 (GRCm39)	missense	probably damaging	1.00
IGL02216:Dync1h1	APN	12	110,629,436 (GRCm39)	missense	probably damaging	0.98
IGL02298:Dync1h1	APN	12	110,607,322 (GRCm39)	missense	probably damaging	1.00
IGL02422:Dync1h1	APN	12	110,606,644 (GRCm39)	missense	possibly damaging	0.68
IGL02610:Dync1h1	APN	12	110,625,666 (GRCm39)	nonsense	probably null
IGL02643:Dync1h1	APN	12	110,625,706 (GRCm39)	unclassified	probably benign
IGL03076:Dync1h1	APN	12	110,624,327 (GRCm39)	missense	probably damaging	1.00
IGL03292:Dync1h1	APN	12	110,632,989 (GRCm39)	splice site	probably null
IGL03293:Dync1h1	APN	12	110,595,168 (GRCm39)	missense	probably benign	0.12
IGL03299:Dync1h1	APN	12	110,585,644 (GRCm39)	missense	possibly damaging	0.49
chinashop	UTSW	12	110,624,568 (GRCm39)	missense	probably damaging	1.00
Gesund	UTSW	12	110,582,838 (GRCm39)	missense	probably benign	0.35
gymnast	UTSW	12	110,584,802 (GRCm39)	missense	probably damaging	1.00
Lightfoot	UTSW	12	110,584,354 (GRCm39)	missense	probably damaging	1.00
Lissom	UTSW	12	110,599,254 (GRCm39)	missense	possibly damaging	0.68
Strong	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
waters	UTSW	12	110,596,113 (GRCm39)	missense	probably damaging	1.00
ANU05:Dync1h1	UTSW	12	110,615,538 (GRCm39)	missense	probably benign	0.31
H8562:Dync1h1	UTSW	12	110,583,241 (GRCm39)	missense	probably benign	0.01
R0082:Dync1h1	UTSW	12	110,602,880 (GRCm39)	missense	probably benign
R0110:Dync1h1	UTSW	12	110,606,378 (GRCm39)	missense	probably benign	0.42
R0130:Dync1h1	UTSW	12	110,585,108 (GRCm39)	missense	probably benign	0.16
R0233:Dync1h1	UTSW	12	110,607,414 (GRCm39)	missense	probably benign	0.45
R0233:Dync1h1	UTSW	12	110,607,414 (GRCm39)	missense	probably benign	0.45
R0242:Dync1h1	UTSW	12	110,616,285 (GRCm39)	missense	possibly damaging	0.67
R0242:Dync1h1	UTSW	12	110,616,285 (GRCm39)	missense	possibly damaging	0.67
R0408:Dync1h1	UTSW	12	110,598,126 (GRCm39)	missense	probably benign
R0450:Dync1h1	UTSW	12	110,606,378 (GRCm39)	missense	probably benign	0.42
R0611:Dync1h1	UTSW	12	110,599,222 (GRCm39)	missense	probably damaging	0.97
R0612:Dync1h1	UTSW	12	110,582,930 (GRCm39)	missense	probably damaging	1.00
R0624:Dync1h1	UTSW	12	110,618,181 (GRCm39)	unclassified	probably benign
R0685:Dync1h1	UTSW	12	110,623,626 (GRCm39)	missense	probably damaging	1.00
R0747:Dync1h1	UTSW	12	110,595,718 (GRCm39)	missense	probably damaging	0.99
R0747:Dync1h1	UTSW	12	110,578,845 (GRCm39)	missense	probably benign
R0843:Dync1h1	UTSW	12	110,631,647 (GRCm39)	missense	possibly damaging	0.81
R0970:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1161:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1211:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1214:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1215:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1227:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1230:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1232:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1237:Dync1h1	UTSW	12	110,632,393 (GRCm39)	missense	probably benign	0.00
R1274:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1275:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1289:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1290:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1331:Dync1h1	UTSW	12	110,615,698 (GRCm39)	missense	probably damaging	0.98
R1340:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1383:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1394:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1396:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1397:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1413:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1432:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1500:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1661:Dync1h1	UTSW	12	110,622,791 (GRCm39)	missense	probably damaging	1.00
R1678:Dync1h1	UTSW	12	110,632,096 (GRCm39)	critical splice acceptor site	probably null
R1698:Dync1h1	UTSW	12	110,593,426 (GRCm39)	missense	possibly damaging	0.88
R1767:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1776:Dync1h1	UTSW	12	110,599,362 (GRCm39)	splice site	probably benign
R1812:Dync1h1	UTSW	12	110,629,334 (GRCm39)	missense	possibly damaging	0.46
R1831:Dync1h1	UTSW	12	110,580,493 (GRCm39)	missense	probably damaging	1.00
R1832:Dync1h1	UTSW	12	110,580,493 (GRCm39)	missense	probably damaging	1.00
R1856:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1857:Dync1h1	UTSW	12	110,629,059 (GRCm39)	missense	probably damaging	0.96
R1879:Dync1h1	UTSW	12	110,591,070 (GRCm39)	missense	probably benign	0.04
R1892:Dync1h1	UTSW	12	110,612,738 (GRCm39)	missense	probably damaging	1.00
R1909:Dync1h1	UTSW	12	110,629,063 (GRCm39)	missense	probably damaging	1.00
R1962:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1974:Dync1h1	UTSW	12	110,592,166 (GRCm39)	missense	possibly damaging	0.80
R1999:Dync1h1	UTSW	12	110,632,857 (GRCm39)	critical splice donor site	probably null
R2073:Dync1h1	UTSW	12	110,581,026 (GRCm39)	missense	probably damaging	1.00
R2091:Dync1h1	UTSW	12	110,616,022 (GRCm39)	missense	probably benign	0.07
R2113:Dync1h1	UTSW	12	110,596,420 (GRCm39)	missense	probably damaging	1.00
R2128:Dync1h1	UTSW	12	110,607,316 (GRCm39)	missense	probably damaging	1.00
R2134:Dync1h1	UTSW	12	110,623,065 (GRCm39)	missense	possibly damaging	0.68
R2496:Dync1h1	UTSW	12	110,607,654 (GRCm39)	missense	possibly damaging	0.65
R2680:Dync1h1	UTSW	12	110,609,681 (GRCm39)	missense	probably damaging	1.00
R2890:Dync1h1	UTSW	12	110,583,325 (GRCm39)	missense	probably damaging	1.00
R2964:Dync1h1	UTSW	12	110,607,460 (GRCm39)	critical splice donor site	probably null
R3705:Dync1h1	UTSW	12	110,607,020 (GRCm39)	missense	possibly damaging	0.80
R3708:Dync1h1	UTSW	12	110,609,563 (GRCm39)	missense	probably damaging	0.96
R3735:Dync1h1	UTSW	12	110,598,109 (GRCm39)	missense	probably benign
R3736:Dync1h1	UTSW	12	110,598,109 (GRCm39)	missense	probably benign
R3882:Dync1h1	UTSW	12	110,595,492 (GRCm39)	missense	probably benign	0.41
R3971:Dync1h1	UTSW	12	110,632,399 (GRCm39)	missense	probably benign	0.00
R4017:Dync1h1	UTSW	12	110,609,624 (GRCm39)	missense	probably damaging	1.00
R4032:Dync1h1	UTSW	12	110,584,483 (GRCm39)	nonsense	probably null
R4355:Dync1h1	UTSW	12	110,599,333 (GRCm39)	missense	possibly damaging	0.55
R4514:Dync1h1	UTSW	12	110,623,573 (GRCm39)	missense	possibly damaging	0.76
R4586:Dync1h1	UTSW	12	110,615,917 (GRCm39)	missense	probably benign	0.30
R4619:Dync1h1	UTSW	12	110,605,278 (GRCm39)	missense	probably benign	0.09
R4659:Dync1h1	UTSW	12	110,595,201 (GRCm39)	missense	possibly damaging	0.50
R4676:Dync1h1	UTSW	12	110,628,975 (GRCm39)	missense	probably damaging	0.99
R4688:Dync1h1	UTSW	12	110,621,962 (GRCm39)	missense	probably damaging	0.99
R4732:Dync1h1	UTSW	12	110,615,941 (GRCm39)	nonsense	probably null
R4733:Dync1h1	UTSW	12	110,615,941 (GRCm39)	nonsense	probably null
R4780:Dync1h1	UTSW	12	110,627,630 (GRCm39)	missense	probably damaging	1.00
R4846:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4861:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4861:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4865:Dync1h1	UTSW	12	110,606,235 (GRCm39)	missense	possibly damaging	0.84
R4872:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4873:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4874:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4875:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4927:Dync1h1	UTSW	12	110,629,289 (GRCm39)	missense	possibly damaging	0.82
R4949:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4954:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4956:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4957:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4958:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4984:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4985:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4988:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R5029:Dync1h1	UTSW	12	110,584,444 (GRCm39)	missense	possibly damaging	0.46
R5032:Dync1h1	UTSW	12	110,593,326 (GRCm39)	nonsense	probably null
R5036:Dync1h1	UTSW	12	110,596,969 (GRCm39)	missense	probably damaging	1.00
R5037:Dync1h1	UTSW	12	110,607,341 (GRCm39)	missense	probably benign	0.09
R5105:Dync1h1	UTSW	12	110,584,366 (GRCm39)	missense	probably damaging	0.99
R5122:Dync1h1	UTSW	12	110,596,114 (GRCm39)	missense	probably damaging	1.00
R5156:Dync1h1	UTSW	12	110,595,264 (GRCm39)	missense	probably benign	0.00
R5290:Dync1h1	UTSW	12	110,581,502 (GRCm39)	missense	probably benign	0.03
R5453:Dync1h1	UTSW	12	110,599,099 (GRCm39)	missense	probably benign	0.12
R5540:Dync1h1	UTSW	12	110,627,384 (GRCm39)	missense	probably benign	0.00
R5613:Dync1h1	UTSW	12	110,599,254 (GRCm39)	missense	possibly damaging	0.68
R5626:Dync1h1	UTSW	12	110,607,575 (GRCm39)	missense	probably benign	0.01
R5652:Dync1h1	UTSW	12	110,632,422 (GRCm39)	missense	possibly damaging	0.70
R5655:Dync1h1	UTSW	12	110,595,496 (GRCm39)	missense	probably benign	0.03
R5686:Dync1h1	UTSW	12	110,582,838 (GRCm39)	missense	probably benign	0.35
R5772:Dync1h1	UTSW	12	110,612,707 (GRCm39)	nonsense	probably null
R5806:Dync1h1	UTSW	12	110,618,087 (GRCm39)	missense	probably damaging	1.00
R5891:Dync1h1	UTSW	12	110,580,654 (GRCm39)	critical splice donor site	probably null
R5921:Dync1h1	UTSW	12	110,584,802 (GRCm39)	missense	probably damaging	1.00
R5965:Dync1h1	UTSW	12	110,599,212 (GRCm39)	missense	probably benign
R6113:Dync1h1	UTSW	12	110,586,848 (GRCm39)	missense	probably benign
R6119:Dync1h1	UTSW	12	110,594,440 (GRCm39)	missense	possibly damaging	0.82
R6154:Dync1h1	UTSW	12	110,584,427 (GRCm39)	missense	probably damaging	1.00
R6339:Dync1h1	UTSW	12	110,612,639 (GRCm39)	missense	probably damaging	0.97
R6522:Dync1h1	UTSW	12	110,583,171 (GRCm39)	missense	probably damaging	0.99
R6531:Dync1h1	UTSW	12	110,584,354 (GRCm39)	missense	probably damaging	1.00
R6554:Dync1h1	UTSW	12	110,616,282 (GRCm39)	missense	probably benign	0.06
R6672:Dync1h1	UTSW	12	110,624,568 (GRCm39)	missense	probably damaging	1.00
R6746:Dync1h1	UTSW	12	110,618,087 (GRCm39)	missense	probably damaging	1.00
R6785:Dync1h1	UTSW	12	110,596,113 (GRCm39)	missense	probably damaging	1.00
R6857:Dync1h1	UTSW	12	110,624,981 (GRCm39)	missense	possibly damaging	0.94
R6863:Dync1h1	UTSW	12	110,618,614 (GRCm39)	missense	probably benign	0.07
R6881:Dync1h1	UTSW	12	110,590,995 (GRCm39)	missense	probably damaging	1.00
R6892:Dync1h1	UTSW	12	110,605,335 (GRCm39)	missense	probably benign	0.00
R7015:Dync1h1	UTSW	12	110,632,521 (GRCm39)	nonsense	probably null
R7096:Dync1h1	UTSW	12	110,623,512 (GRCm39)	missense	probably damaging	0.99
R7173:Dync1h1	UTSW	12	110,568,173 (GRCm39)	missense	probably benign
R7224:Dync1h1	UTSW	12	110,584,196 (GRCm39)	missense	possibly damaging	0.93
R7295:Dync1h1	UTSW	12	110,631,183 (GRCm39)	critical splice donor site	probably null
R7308:Dync1h1	UTSW	12	110,631,596 (GRCm39)	missense	possibly damaging	0.91
R7346:Dync1h1	UTSW	12	110,602,076 (GRCm39)	missense	probably damaging	1.00
R7359:Dync1h1	UTSW	12	110,591,036 (GRCm39)	missense	probably benign	0.00
R7405:Dync1h1	UTSW	12	110,600,654 (GRCm39)	missense	probably damaging	1.00
R7439:Dync1h1	UTSW	12	110,602,887 (GRCm39)	missense	probably damaging	1.00
R7441:Dync1h1	UTSW	12	110,602,887 (GRCm39)	missense	probably damaging	1.00
R7472:Dync1h1	UTSW	12	110,632,109 (GRCm39)	missense	probably damaging	0.99
R7532:Dync1h1	UTSW	12	110,618,011 (GRCm39)	missense	probably benign	0.00
R7543:Dync1h1	UTSW	12	110,580,541 (GRCm39)	missense	probably benign	0.04
R7555:Dync1h1	UTSW	12	110,597,059 (GRCm39)	missense	probably benign	0.03
R7632:Dync1h1	UTSW	12	110,627,327 (GRCm39)	missense	probably benign	0.10
R7701:Dync1h1	UTSW	12	110,585,080 (GRCm39)	missense	probably damaging	1.00
R7704:Dync1h1	UTSW	12	110,632,200 (GRCm39)	missense	probably damaging	1.00
R7808:Dync1h1	UTSW	12	110,621,893 (GRCm39)	missense	possibly damaging	0.53
R7891:Dync1h1	UTSW	12	110,609,590 (GRCm39)	missense	probably benign	0.02
R7895:Dync1h1	UTSW	12	110,582,891 (GRCm39)	missense	probably damaging	1.00
R7913:Dync1h1	UTSW	12	110,595,168 (GRCm39)	missense	probably benign	0.12
R8164:Dync1h1	UTSW	12	110,582,794 (GRCm39)	missense	possibly damaging	0.91
R8257:Dync1h1	UTSW	12	110,602,908 (GRCm39)	missense	probably damaging	1.00
R8346:Dync1h1	UTSW	12	110,632,226 (GRCm39)	missense	probably benign	0.21
R8432:Dync1h1	UTSW	12	110,584,576 (GRCm39)	missense	probably benign	0.00
R8510:Dync1h1	UTSW	12	110,583,177 (GRCm39)	missense	possibly damaging	0.94
R8731:Dync1h1	UTSW	12	110,607,018 (GRCm39)	missense	possibly damaging	0.93
R8739:Dync1h1	UTSW	12	110,581,014 (GRCm39)	missense	probably damaging	1.00
R8756:Dync1h1	UTSW	12	110,583,261 (GRCm39)	missense	probably benign	0.06
R8855:Dync1h1	UTSW	12	110,602,333 (GRCm39)	missense	probably damaging	1.00
R8866:Dync1h1	UTSW	12	110,602,333 (GRCm39)	missense	probably damaging	1.00
R8885:Dync1h1	UTSW	12	110,583,172 (GRCm39)	missense	probably damaging	1.00
R8893:Dync1h1	UTSW	12	110,608,477 (GRCm39)	missense	probably damaging	1.00
R8913:Dync1h1	UTSW	12	110,624,602 (GRCm39)	missense	probably benign	0.14
R8937:Dync1h1	UTSW	12	110,584,471 (GRCm39)	missense	probably damaging	1.00
R8958:Dync1h1	UTSW	12	110,586,805 (GRCm39)	missense	probably benign	0.00
R9000:Dync1h1	UTSW	12	110,606,397 (GRCm39)	missense	probably benign
R9036:Dync1h1	UTSW	12	110,606,186 (GRCm39)	missense	probably benign
R9090:Dync1h1	UTSW	12	110,583,310 (GRCm39)	missense	probably benign	0.06
R9108:Dync1h1	UTSW	12	110,622,706 (GRCm39)	intron	probably benign
R9161:Dync1h1	UTSW	12	110,625,023 (GRCm39)	missense	probably benign	0.01
R9185:Dync1h1	UTSW	12	110,601,937 (GRCm39)	missense	probably benign	0.33
R9271:Dync1h1	UTSW	12	110,583,310 (GRCm39)	missense	probably benign	0.06
R9436:Dync1h1	UTSW	12	110,582,975 (GRCm39)	missense	probably damaging	1.00
R9478:Dync1h1	UTSW	12	110,625,137 (GRCm39)	missense	probably benign	0.02
R9547:Dync1h1	UTSW	12	110,624,805 (GRCm39)	missense	probably damaging	1.00
R9561:Dync1h1	UTSW	12	110,615,533 (GRCm39)	missense	probably damaging	0.99
R9586:Dync1h1	UTSW	12	110,582,975 (GRCm39)	missense	probably damaging	1.00
R9609:Dync1h1	UTSW	12	110,607,362 (GRCm39)	missense	probably benign	0.01
Z1088:Dync1h1	UTSW	12	110,596,351 (GRCm39)	frame shift	probably null
Z1177:Dync1h1	UTSW	12	110,624,951 (GRCm39)	nonsense	probably null
Z1177:Dync1h1	UTSW	12	110,607,611 (GRCm39)	frame shift	probably null
Z1177:Dync1h1	UTSW	12	110,603,988 (GRCm39)	missense	probably damaging	1.00

Posted On

2013-10-07