Incidental Mutation 'IGL01371:Vmn1r83'
ID76156
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r83
Ensembl Gene ENSMUSG00000066804
Gene Namevomeronasal 1 receptor 83
SynonymsV1rg8
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.073) question?
Stock #IGL01371
Quality Score
Status
Chromosome7
Chromosomal Location12319707-12329481 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 12321233 bp
ZygosityHeterozygous
Amino Acid Change Phenylalanine to Serine at position 299 (F299S)
Ref Sequence ENSEMBL: ENSMUSP00000154521 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000086229] [ENSMUST00000226701]
Predicted Effect probably benign
Transcript: ENSMUST00000086229
AA Change: F299S

PolyPhen 2 Score 0.103 (Sensitivity: 0.93; Specificity: 0.86)
SMART Domains Protein: ENSMUSP00000083406
Gene: ENSMUSG00000066804
AA Change: F299S

DomainStartEndE-ValueType
Pfam:TAS2R 1 303 1.3e-8 PFAM
Pfam:V1R 26 299 1.7e-28 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000226701
AA Change: F299S

PolyPhen 2 Score 0.103 (Sensitivity: 0.93; Specificity: 0.86)
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 31 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1300017J02Rik T C 9: 103,254,776 E504G possibly damaging Het
Abcc9 C T 6: 142,656,614 R691Q probably benign Het
AI314180 A G 4: 58,809,718 L1583P probably damaging Het
Ambra1 G T 2: 91,825,286 G700W probably damaging Het
Atp6v1c1 A G 15: 38,682,960 I198V probably benign Het
Bptf T C 11: 107,055,907 N2353S probably benign Het
Cd84 A T 1: 171,886,370 T312S probably benign Het
Chl1 G T 6: 103,715,364 C1064F probably damaging Het
Clca4a T C 3: 144,960,672 D473G probably damaging Het
Dsp A G 13: 38,193,617 R1793G probably benign Het
Dync1h1 A G 12: 110,638,851 N2374S probably benign Het
Gm43191 A T 3: 116,645,463 I130N probably damaging Het
Gm5134 T G 10: 76,004,747 L475R probably damaging Het
Grm1 A G 10: 10,720,039 V615A probably benign Het
Loxl1 T A 9: 58,294,422 Q462L possibly damaging Het
Nwd1 T C 8: 72,675,115 W755R probably damaging Het
Olfr1102 A T 2: 87,002,923 K318M probably benign Het
Olfr1408 A G 1: 173,130,531 S229P possibly damaging Het
Olfr1459 G A 19: 13,145,828 T277I possibly damaging Het
Otud4 T C 8: 79,673,761 F1034L probably damaging Het
Pakap C A 4: 57,856,325 D551E probably benign Het
Panx3 T G 9: 37,661,475 T260P probably benign Het
Ppfia4 A T 1: 134,328,086 S194T probably benign Het
Rnf135 T A 11: 80,189,255 I124N probably benign Het
Rpf1 T C 3: 146,507,547 N283S probably damaging Het
Smg5 A G 3: 88,359,644 probably benign Het
Stard9 A G 2: 120,701,368 E2702G probably benign Het
Tbk1 A T 10: 121,559,871 M439K probably benign Het
Tmem235 T C 11: 117,862,306 L85P possibly damaging Het
Trhde A T 10: 114,588,500 V460E possibly damaging Het
Ttn T C 2: 76,790,264 probably benign Het
Other mutations in Vmn1r83
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01447:Vmn1r83 APN 7 12321497 missense probably benign
IGL01793:Vmn1r83 APN 7 12321577 missense probably benign 0.02
IGL02137:Vmn1r83 APN 7 12321834 missense probably damaging 1.00
IGL03155:Vmn1r83 APN 7 12321690 missense probably benign
IGL03182:Vmn1r83 APN 7 12321690 missense probably benign
R0627:Vmn1r83 UTSW 7 12321992 missense probably damaging 0.99
R1511:Vmn1r83 UTSW 7 12321270 missense possibly damaging 0.87
R3882:Vmn1r83 UTSW 7 12321402 missense probably damaging 1.00
R4613:Vmn1r83 UTSW 7 12321768 missense probably benign 0.00
R4678:Vmn1r83 UTSW 7 12321770 missense possibly damaging 0.67
R5580:Vmn1r83 UTSW 7 12321873 missense probably benign 0.01
R6982:Vmn1r83 UTSW 7 12321836 missense probably damaging 1.00
R7440:Vmn1r83 UTSW 7 12321629 missense probably damaging 1.00
R7476:Vmn1r83 UTSW 7 12321615 missense possibly damaging 0.93
R7522:Vmn1r83 UTSW 7 12321578 missense possibly damaging 0.61
R7759:Vmn1r83 UTSW 7 12321433 missense probably benign 0.06
Posted On2013-10-07