Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01371:Vmn1r83'

76156

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r83

Ensembl Gene

ENSMUSG00000066804

Gene Name

vomeronasal 1 receptor 83

Synonyms

V1rg8

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.057) question?

Stock #

IGL01371

Quality Score

Status

Chromosome

Chromosomal Location

12319707-12329481 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 12321233 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Serine at position 299 (F299S)

Ref Sequence

ENSEMBL: ENSMUSP00000154521 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000086229] [ENSMUST00000226701]

AlphaFold

Q8R287

Predicted Effect

probably benign
Transcript: ENSMUST00000086229
AA Change: F299S

PolyPhen 2 Score 0.103 (Sensitivity: 0.93; Specificity: 0.86)

SMART Domains

Protein: ENSMUSP00000083406
Gene: ENSMUSG00000066804
AA Change: F299S

Domain	Start	End	E-Value	Type
Pfam:TAS2R	1	303	1.3e-8	PFAM
Pfam:V1R	26	299	1.7e-28	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000226701
AA Change: F299S

PolyPhen 2 Score 0.103 (Sensitivity: 0.93; Specificity: 0.86)

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 31 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1300017J02Rik	T	C	9: 103,254,776	E504G	possibly damaging	Het
Abcc9	C	T	6: 142,656,614	R691Q	probably benign	Het
AI314180	A	G	4: 58,809,718	L1583P	probably damaging	Het
Ambra1	G	T	2: 91,825,286	G700W	probably damaging	Het
Atp6v1c1	A	G	15: 38,682,960	I198V	probably benign	Het
Bptf	T	C	11: 107,055,907	N2353S	probably benign	Het
Cd84	A	T	1: 171,886,370	T312S	probably benign	Het
Chl1	G	T	6: 103,715,364	C1064F	probably damaging	Het
Clca4a	T	C	3: 144,960,672	D473G	probably damaging	Het
Dsp	A	G	13: 38,193,617	R1793G	probably benign	Het
Dync1h1	A	G	12: 110,638,851	N2374S	probably benign	Het
Gm43191	A	T	3: 116,645,463	I130N	probably damaging	Het
Gm5134	T	G	10: 76,004,747	L475R	probably damaging	Het
Grm1	A	G	10: 10,720,039	V615A	probably benign	Het
Loxl1	T	A	9: 58,294,422	Q462L	possibly damaging	Het
Nwd1	T	C	8: 72,675,115	W755R	probably damaging	Het
Olfr1102	A	T	2: 87,002,923	K318M	probably benign	Het
Olfr1408	A	G	1: 173,130,531	S229P	possibly damaging	Het
Olfr1459	G	A	19: 13,145,828	T277I	possibly damaging	Het
Otud4	T	C	8: 79,673,761	F1034L	probably damaging	Het
Pakap	C	A	4: 57,856,325	D551E	probably benign	Het
Panx3	T	G	9: 37,661,475	T260P	probably benign	Het
Ppfia4	A	T	1: 134,328,086	S194T	probably benign	Het
Rnf135	T	A	11: 80,189,255	I124N	probably benign	Het
Rpf1	T	C	3: 146,507,547	N283S	probably damaging	Het
Smg5	A	G	3: 88,359,644		probably benign	Het
Stard9	A	G	2: 120,701,368	E2702G	probably benign	Het
Tbk1	A	T	10: 121,559,871	M439K	probably benign	Het
Tmem235	T	C	11: 117,862,306	L85P	possibly damaging	Het
Trhde	A	T	10: 114,588,500	V460E	possibly damaging	Het
Ttn	T	C	2: 76,790,264		probably benign	Het

Other mutations in Vmn1r83

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01447:Vmn1r83	APN	7	12321497	missense	probably benign
IGL01793:Vmn1r83	APN	7	12321577	missense	probably benign	0.02
IGL02137:Vmn1r83	APN	7	12321834	missense	probably damaging	1.00
IGL03155:Vmn1r83	APN	7	12321690	missense	probably benign
IGL03182:Vmn1r83	APN	7	12321690	missense	probably benign
R0627:Vmn1r83	UTSW	7	12321992	missense	probably damaging	0.99
R1511:Vmn1r83	UTSW	7	12321270	missense	possibly damaging	0.87
R3882:Vmn1r83	UTSW	7	12321402	missense	probably damaging	1.00
R4613:Vmn1r83	UTSW	7	12321768	missense	probably benign	0.00
R4678:Vmn1r83	UTSW	7	12321770	missense	possibly damaging	0.67
R5580:Vmn1r83	UTSW	7	12321873	missense	probably benign	0.01
R6982:Vmn1r83	UTSW	7	12321836	missense	probably damaging	1.00
R7440:Vmn1r83	UTSW	7	12321629	missense	probably damaging	1.00
R7476:Vmn1r83	UTSW	7	12321615	missense	possibly damaging	0.93
R7522:Vmn1r83	UTSW	7	12321578	missense	possibly damaging	0.61
R7759:Vmn1r83	UTSW	7	12321433	missense	probably benign	0.06
R8886:Vmn1r83	UTSW	7	12321916	missense	probably benign	0.10
R9077:Vmn1r83	UTSW	7	12321644	missense	probably damaging	1.00

Posted On

2013-10-07