Incidental Mutation 'P0031:Glipr1l1'
ID7711
Institutional Source Beutler Lab
Gene Symbol Glipr1l1
Ensembl Gene ENSMUSG00000020213
Gene NameGLI pathogenesis-related 1 like 1
Synonyms1700011E04Rik
MMRRC Submission 038283-MU
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.050) question?
Stock #P0031 (G1)
Quality Score
Status Validated
Chromosome10
Chromosomal Location112060189-112078510 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) C to A at 112060387 bp
ZygosityHeterozygous
Amino Acid Change Phenylalanine to Leucine at position 26 (F26L)
Ref Sequence ENSEMBL: ENSMUSP00000073302 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000073617]
Predicted Effect probably benign
Transcript: ENSMUST00000073617
AA Change: F26L

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000073302
Gene: ENSMUSG00000020213
AA Change: F26L

DomainStartEndE-ValueType
SCP 40 186 6.52e-50 SMART
Meta Mutation Damage Score 0.0898 question?
Coding Region Coverage
  • 1x: 80.2%
  • 3x: 70.9%
  • 10x: 42.6%
  • 20x: 20.3%
Validation Efficiency 85% (81/95)
Allele List at MGI
Other mutations in this stock
Total: 11 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Dcc A G 18: 71,384,228 probably benign Het
Epb41l3 T A 17: 69,259,054 L410* probably null Het
Fcer1a T A 1: 173,225,332 K99M probably benign Het
Frmd4b A G 6: 97,354,030 F132S probably damaging Het
Letmd1 A G 15: 100,472,609 N62D probably damaging Het
Lyst A G 13: 13,664,031 E1844G probably damaging Het
Pcdhb4 A G 18: 37,308,885 Y416C probably damaging Het
Rcn1 T A 2: 105,389,069 K260* probably null Het
Tcerg1 A G 18: 42,573,302 I1015V probably benign Het
Tet2 T A 3: 133,480,202 Y1158F possibly damaging Het
Zmynd8 T C 2: 165,820,698 probably benign Het
Other mutations in Glipr1l1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00467:Glipr1l1 APN 10 112078381 missense probably benign 0.02
IGL01660:Glipr1l1 APN 10 112072279 missense probably damaging 0.97
IGL01893:Glipr1l1 APN 10 112076169 missense probably benign 0.06
IGL02576:Glipr1l1 APN 10 112060319 missense possibly damaging 0.77
IGL03309:Glipr1l1 APN 10 112072236 splice site probably benign
R0987:Glipr1l1 UTSW 10 112078435 missense probably benign
R0992:Glipr1l1 UTSW 10 112062325 missense probably benign
R2136:Glipr1l1 UTSW 10 112060476 missense probably damaging 1.00
R2248:Glipr1l1 UTSW 10 112062287 missense probably benign 0.09
R4297:Glipr1l1 UTSW 10 112062347 missense probably benign 0.05
R4298:Glipr1l1 UTSW 10 112062347 missense probably benign 0.05
R4569:Glipr1l1 UTSW 10 112062412 missense probably benign 0.00
R5015:Glipr1l1 UTSW 10 112078374 missense probably benign 0.00
R5552:Glipr1l1 UTSW 10 112062338 missense probably benign 0.00
R5629:Glipr1l1 UTSW 10 112078403 missense possibly damaging 0.90
R6061:Glipr1l1 UTSW 10 112076170 missense probably benign 0.32
R6237:Glipr1l1 UTSW 10 112060427 nonsense probably null
R6519:Glipr1l1 UTSW 10 112062248 missense probably benign 0.02
R6913:Glipr1l1 UTSW 10 112062434 critical splice donor site probably null
R7621:Glipr1l1 UTSW 10 112060395 missense probably benign 0.00
R8171:Glipr1l1 UTSW 10 112078384 missense probably benign 0.01
X0023:Glipr1l1 UTSW 10 112078439 missense probably damaging 0.98
Z1177:Glipr1l1 UTSW 10 112078390 missense probably benign 0.00
Posted On2012-10-29