Incidental Mutation 'R0848:Phf3'
| ID |
77393 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Phf3
|
| Ensembl Gene |
ENSMUSG00000048874 |
| Gene Name |
PHD finger protein 3 |
| Synonyms |
AU020177, 2310061N19Rik |
| MMRRC Submission |
039027-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0848 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
30841417-30912989 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 30902253 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 20
(L20P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000140935
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000088310]
[ENSMUST00000186733]
[ENSMUST00000187968]
[ENSMUST00000188780]
[ENSMUST00000191064]
|
| AlphaFold |
B2RQG2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000088310
AA Change: L20P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000085650
Gene: ENSMUSG00000048874
AA Change: L20P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
337 |
344 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
651 |
660 |
N/A |
INTRINSIC |
|
PHD
|
697 |
748 |
3.82e-10 |
SMART |
|
low complexity region
|
847 |
859 |
N/A |
INTRINSIC |
|
low complexity region
|
876 |
887 |
N/A |
INTRINSIC |
|
TFS2M
|
908 |
1008 |
1.28e-47 |
SMART |
|
Pfam:SPOC
|
1188 |
1294 |
4.2e-26 |
PFAM |
|
low complexity region
|
1367 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1516 |
1529 |
N/A |
INTRINSIC |
|
low complexity region
|
1597 |
1620 |
N/A |
INTRINSIC |
|
low complexity region
|
1796 |
1811 |
N/A |
INTRINSIC |
|
low complexity region
|
1813 |
1846 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000186105
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000186733
AA Change: L20P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000139610
Gene: ENSMUSG00000048874
AA Change: L20P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
337 |
344 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
651 |
660 |
N/A |
INTRINSIC |
|
PHD
|
697 |
748 |
3.82e-10 |
SMART |
|
low complexity region
|
847 |
859 |
N/A |
INTRINSIC |
|
low complexity region
|
876 |
887 |
N/A |
INTRINSIC |
|
TFS2M
|
908 |
1008 |
1.28e-47 |
SMART |
|
Pfam:SPOC
|
1188 |
1294 |
4.2e-26 |
PFAM |
|
low complexity region
|
1367 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1516 |
1529 |
N/A |
INTRINSIC |
|
low complexity region
|
1597 |
1620 |
N/A |
INTRINSIC |
|
low complexity region
|
1796 |
1811 |
N/A |
INTRINSIC |
|
low complexity region
|
1813 |
1846 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000187600
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000187968
AA Change: L20P
PolyPhen 2
Score 0.933 (Sensitivity: 0.80; Specificity: 0.94)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000188780
AA Change: L20P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000140935
Gene: ENSMUSG00000048874
AA Change: L20P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
158 |
169 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000191064
AA Change: L20P
PolyPhen 2
Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192050
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000191245
|
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.7%
- 10x: 97.3%
- 20x: 94.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of a PHD finger-containing gene family. This gene may function as a transcription factor and may be involved in glioblastomas development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 70 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aass |
A |
T |
6: 23,114,984 (GRCm39) |
H181Q |
probably damaging |
Het |
| Abca13 |
T |
A |
11: 9,632,011 (GRCm39) |
L4977* |
probably null |
Het |
| Abca8a |
T |
A |
11: 109,919,016 (GRCm39) |
Y1550F |
probably damaging |
Het |
| Actr2 |
C |
T |
11: 20,022,584 (GRCm39) |
E296K |
probably benign |
Het |
| Agtpbp1 |
A |
T |
13: 59,681,753 (GRCm39) |
|
probably benign |
Het |
| Anks1b |
A |
C |
10: 89,906,987 (GRCm39) |
E268A |
probably damaging |
Het |
| C1rl |
A |
G |
6: 124,485,465 (GRCm39) |
T279A |
probably benign |
Het |
| C5ar2 |
T |
C |
7: 15,971,526 (GRCm39) |
T134A |
probably benign |
Het |
| Cdkl3 |
G |
A |
11: 51,902,094 (GRCm39) |
R101Q |
probably damaging |
Het |
| Celsr2 |
A |
T |
3: 108,321,654 (GRCm39) |
F386Y |
probably benign |
Het |
| Chd1 |
C |
T |
17: 15,990,503 (GRCm39) |
P1685L |
probably damaging |
Het |
| Chrne |
G |
T |
11: 70,506,239 (GRCm39) |
H402Q |
probably benign |
Het |
| Clvs1 |
A |
G |
4: 9,282,003 (GRCm39) |
D149G |
possibly damaging |
Het |
| Cntnap5b |
T |
C |
1: 100,182,888 (GRCm39) |
Y620H |
probably benign |
Het |
| Col6a1 |
A |
G |
10: 76,549,458 (GRCm39) |
|
probably null |
Het |
| Cyp2d26 |
T |
A |
15: 82,674,434 (GRCm39) |
I483F |
probably benign |
Het |
| Dlx6 |
C |
T |
6: 6,863,665 (GRCm39) |
Q96* |
probably null |
Het |
| Dmac2l |
A |
T |
12: 69,788,584 (GRCm39) |
H161L |
probably benign |
Het |
| Eif1a |
T |
A |
18: 46,741,114 (GRCm39) |
N116K |
possibly damaging |
Het |
| Epb41l5 |
A |
T |
1: 119,477,684 (GRCm39) |
C696S |
probably benign |
Het |
| Exoc7 |
A |
G |
11: 116,186,074 (GRCm39) |
S376P |
possibly damaging |
Het |
| Fads1 |
C |
T |
19: 10,160,429 (GRCm39) |
P5L |
probably benign |
Het |
| G3bp1 |
T |
C |
11: 55,389,452 (GRCm39) |
F383L |
probably damaging |
Het |
| Gimap7 |
T |
C |
6: 48,700,657 (GRCm39) |
I81T |
probably damaging |
Het |
| Gtf2a1l |
T |
C |
17: 89,001,657 (GRCm39) |
V171A |
probably damaging |
Het |
| Hax1 |
A |
G |
3: 89,902,940 (GRCm39) |
S253P |
probably damaging |
Het |
| Hsd3b5 |
A |
T |
3: 98,526,671 (GRCm39) |
D258E |
probably damaging |
Het |
| Kcnb1 |
G |
T |
2: 166,948,187 (GRCm39) |
F220L |
probably damaging |
Het |
| Kif1a |
T |
A |
1: 92,947,620 (GRCm39) |
Y1708F |
probably damaging |
Het |
| Krt14 |
A |
T |
11: 100,095,090 (GRCm39) |
I379N |
probably damaging |
Het |
| Lpxn |
A |
G |
19: 12,781,401 (GRCm39) |
I40V |
probably benign |
Het |
| Lrp1 |
C |
T |
10: 127,389,231 (GRCm39) |
|
probably null |
Het |
| Lyst |
G |
A |
13: 13,809,515 (GRCm39) |
R395H |
probably benign |
Het |
| Mindy4 |
G |
A |
6: 55,295,271 (GRCm39) |
W737* |
probably null |
Het |
| Mki67 |
C |
A |
7: 135,302,772 (GRCm39) |
R754L |
probably benign |
Het |
| Morf4l1 |
A |
G |
9: 89,982,502 (GRCm39) |
V144A |
probably benign |
Het |
| Mvb12a |
T |
C |
8: 71,998,422 (GRCm39) |
S186P |
probably benign |
Het |
| Myrf |
G |
C |
19: 10,195,526 (GRCm39) |
T428S |
probably benign |
Het |
| Nipal1 |
A |
G |
5: 72,825,183 (GRCm39) |
N292S |
probably damaging |
Het |
| Nqo2 |
T |
G |
13: 34,156,461 (GRCm39) |
|
probably null |
Het |
| Or14a256 |
T |
C |
7: 86,264,848 (GRCm39) |
Y335C |
probably damaging |
Het |
| Or2d3b |
A |
G |
7: 106,514,200 (GRCm39) |
K265R |
probably benign |
Het |
| Or5ak24 |
A |
T |
2: 85,260,365 (GRCm39) |
N269K |
probably benign |
Het |
| Or6c214 |
C |
T |
10: 129,591,077 (GRCm39) |
V81I |
probably benign |
Het |
| Osbpl7 |
C |
A |
11: 96,951,350 (GRCm39) |
P507Q |
probably damaging |
Het |
| Pcdhb1 |
G |
A |
18: 37,400,475 (GRCm39) |
G809S |
probably benign |
Het |
| Pcm1 |
T |
C |
8: 41,735,720 (GRCm39) |
V846A |
probably damaging |
Het |
| Pih1d1 |
A |
G |
7: 44,807,041 (GRCm39) |
T58A |
probably damaging |
Het |
| Plekhn1 |
A |
G |
4: 156,308,021 (GRCm39) |
|
probably null |
Het |
| Plvap |
A |
T |
8: 71,959,526 (GRCm39) |
L422Q |
probably damaging |
Het |
| Polq |
C |
T |
16: 36,882,492 (GRCm39) |
A1273V |
probably benign |
Het |
| Prelid2 |
T |
A |
18: 42,068,289 (GRCm39) |
I51F |
probably damaging |
Het |
| Ptpn18 |
G |
A |
1: 34,501,783 (GRCm39) |
D8N |
probably damaging |
Het |
| Ptpra |
T |
A |
2: 130,360,911 (GRCm39) |
F190Y |
probably damaging |
Het |
| Pus7l |
A |
G |
15: 94,438,393 (GRCm39) |
S151P |
probably benign |
Het |
| Rsph6a |
G |
A |
7: 18,791,595 (GRCm39) |
D255N |
probably benign |
Het |
| Serpinb6c |
A |
T |
13: 34,083,288 (GRCm39) |
V42D |
probably damaging |
Het |
| Slc7a13 |
A |
G |
4: 19,818,866 (GRCm39) |
N22S |
probably benign |
Het |
| Snx5 |
G |
A |
2: 144,095,726 (GRCm39) |
R312C |
probably damaging |
Het |
| Stard9 |
T |
C |
2: 120,526,304 (GRCm39) |
S854P |
probably damaging |
Het |
| Syne2 |
AAGAG |
AAGAGAGAG |
12: 76,144,733 (GRCm39) |
|
probably null |
Het |
| Syne2 |
AGAGTGAG |
AGAGTGAGTGAG |
12: 76,144,734 (GRCm39) |
|
probably null |
Het |
| Tlr12 |
A |
G |
4: 128,510,084 (GRCm39) |
I722T |
probably benign |
Het |
| Tmem101 |
A |
T |
11: 102,046,692 (GRCm39) |
M59K |
possibly damaging |
Het |
| Trim34a |
C |
T |
7: 103,910,331 (GRCm39) |
R378C |
probably benign |
Het |
| Trim35 |
T |
A |
14: 66,546,574 (GRCm39) |
M447K |
probably benign |
Het |
| Trps1 |
C |
A |
15: 50,524,945 (GRCm39) |
S704I |
possibly damaging |
Het |
| Vmn1r231 |
T |
A |
17: 21,110,433 (GRCm39) |
S161C |
probably damaging |
Het |
| Vps13a |
A |
C |
19: 16,676,261 (GRCm39) |
N1237K |
probably damaging |
Het |
| Zfp619 |
G |
T |
7: 39,185,983 (GRCm39) |
C671F |
probably damaging |
Het |
|
| Other mutations in Phf3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00234:Phf3
|
APN |
1 |
30,850,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00704:Phf3
|
APN |
1 |
30,843,919 (GRCm39) |
missense |
probably benign |
|
|
IGL01147:Phf3
|
APN |
1 |
30,843,250 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01360:Phf3
|
APN |
1 |
30,847,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01376:Phf3
|
APN |
1 |
30,869,566 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
IGL01396:Phf3
|
APN |
1 |
30,843,386 (GRCm39) |
nonsense |
probably null |
|
|
IGL01830:Phf3
|
APN |
1 |
30,853,148 (GRCm39) |
nonsense |
probably null |
|
|
IGL02108:Phf3
|
APN |
1 |
30,869,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02156:Phf3
|
APN |
1 |
30,847,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02576:Phf3
|
APN |
1 |
30,869,117 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03031:Phf3
|
APN |
1 |
30,843,734 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03334:Phf3
|
APN |
1 |
30,844,810 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03411:Phf3
|
APN |
1 |
30,843,482 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4976:Phf3
|
UTSW |
1 |
30,844,104 (GRCm39) |
utr 3 prime |
probably benign |
|
|
PIT4458001:Phf3
|
UTSW |
1 |
30,855,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0037:Phf3
|
UTSW |
1 |
30,843,999 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0052:Phf3
|
UTSW |
1 |
30,847,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0114:Phf3
|
UTSW |
1 |
30,844,524 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0123:Phf3
|
UTSW |
1 |
30,844,146 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0225:Phf3
|
UTSW |
1 |
30,844,146 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0715:Phf3
|
UTSW |
1 |
30,850,919 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0835:Phf3
|
UTSW |
1 |
30,869,632 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1473:Phf3
|
UTSW |
1 |
30,845,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1522:Phf3
|
UTSW |
1 |
30,844,729 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1549:Phf3
|
UTSW |
1 |
30,843,923 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1555:Phf3
|
UTSW |
1 |
30,844,958 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1780:Phf3
|
UTSW |
1 |
30,851,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1789:Phf3
|
UTSW |
1 |
30,845,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1875:Phf3
|
UTSW |
1 |
30,869,704 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1912:Phf3
|
UTSW |
1 |
30,843,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1957:Phf3
|
UTSW |
1 |
30,870,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2019:Phf3
|
UTSW |
1 |
30,850,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2259:Phf3
|
UTSW |
1 |
30,843,424 (GRCm39) |
missense |
probably benign |
0.20 |
|
R2305:Phf3
|
UTSW |
1 |
30,844,556 (GRCm39) |
nonsense |
probably null |
|
|
R2345:Phf3
|
UTSW |
1 |
30,844,432 (GRCm39) |
nonsense |
probably null |
|
|
R2424:Phf3
|
UTSW |
1 |
30,845,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2497:Phf3
|
UTSW |
1 |
30,869,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2504:Phf3
|
UTSW |
1 |
30,849,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3522:Phf3
|
UTSW |
1 |
30,844,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3816:Phf3
|
UTSW |
1 |
30,844,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4152:Phf3
|
UTSW |
1 |
30,870,539 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4403:Phf3
|
UTSW |
1 |
30,843,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4658:Phf3
|
UTSW |
1 |
30,902,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4663:Phf3
|
UTSW |
1 |
30,860,296 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4669:Phf3
|
UTSW |
1 |
30,869,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4706:Phf3
|
UTSW |
1 |
30,844,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4757:Phf3
|
UTSW |
1 |
30,859,908 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4766:Phf3
|
UTSW |
1 |
30,853,020 (GRCm39) |
unclassified |
probably benign |
|
|
R4786:Phf3
|
UTSW |
1 |
30,855,638 (GRCm39) |
nonsense |
probably null |
|
|
R5107:Phf3
|
UTSW |
1 |
30,870,566 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5155:Phf3
|
UTSW |
1 |
30,863,457 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R5310:Phf3
|
UTSW |
1 |
30,842,887 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5823:Phf3
|
UTSW |
1 |
30,843,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5944:Phf3
|
UTSW |
1 |
30,859,785 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5979:Phf3
|
UTSW |
1 |
30,844,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6007:Phf3
|
UTSW |
1 |
30,843,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:Phf3
|
UTSW |
1 |
30,902,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6072:Phf3
|
UTSW |
1 |
30,869,769 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6533:Phf3
|
UTSW |
1 |
30,845,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6649:Phf3
|
UTSW |
1 |
30,844,104 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6653:Phf3
|
UTSW |
1 |
30,844,104 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6852:Phf3
|
UTSW |
1 |
30,843,711 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6855:Phf3
|
UTSW |
1 |
30,859,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6862:Phf3
|
UTSW |
1 |
30,853,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6930:Phf3
|
UTSW |
1 |
30,850,958 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7135:Phf3
|
UTSW |
1 |
30,870,190 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R7323:Phf3
|
UTSW |
1 |
30,852,211 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7352:Phf3
|
UTSW |
1 |
30,843,407 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7455:Phf3
|
UTSW |
1 |
30,876,239 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7549:Phf3
|
UTSW |
1 |
30,870,556 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7609:Phf3
|
UTSW |
1 |
30,844,582 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7720:Phf3
|
UTSW |
1 |
30,868,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7745:Phf3
|
UTSW |
1 |
30,843,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8134:Phf3
|
UTSW |
1 |
30,863,552 (GRCm39) |
missense |
unknown |
|
|
R8264:Phf3
|
UTSW |
1 |
30,870,138 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8545:Phf3
|
UTSW |
1 |
30,863,391 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8821:Phf3
|
UTSW |
1 |
30,860,347 (GRCm39) |
nonsense |
probably null |
|
|
R8831:Phf3
|
UTSW |
1 |
30,860,347 (GRCm39) |
nonsense |
probably null |
|
|
R8873:Phf3
|
UTSW |
1 |
30,843,773 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R9101:Phf3
|
UTSW |
1 |
30,843,026 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9402:Phf3
|
UTSW |
1 |
30,850,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9426:Phf3
|
UTSW |
1 |
30,870,625 (GRCm39) |
nonsense |
probably null |
|
|
R9594:Phf3
|
UTSW |
1 |
30,869,003 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9707:Phf3
|
UTSW |
1 |
30,868,923 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9803:Phf3
|
UTSW |
1 |
30,869,872 (GRCm39) |
missense |
probably benign |
0.16 |
|
Z1177:Phf3
|
UTSW |
1 |
30,851,049 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1177:Phf3
|
UTSW |
1 |
30,844,132 (GRCm39) |
missense |
unknown |
|
|
Z1177:Phf3
|
UTSW |
1 |
30,843,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGATCATTGCTATCCAAAACAGGCAAAC -3'
(R):5'- CATGTGTGTAAGTCCCACATAACTCACTAAAA -3'
Sequencing Primer
(F):5'- TATCCAAAACAGGCAAACAGAACTG -3'
(R):5'- GTGGACTCACTGTAAAAGCATTG -3'
|
| Posted On |
2013-10-16 |
Incidental Mutation