Incidental Mutation 'R0848:Phf3'
| ID |
77393 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Phf3
|
| Ensembl Gene |
ENSMUSG00000048874 |
| Gene Name |
PHD finger protein 3 |
| Synonyms |
AU020177, 2310061N19Rik |
| MMRRC Submission |
039027-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0848 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
30802339-30873921 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 30863172 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 20
(L20P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000140935
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000088310]
[ENSMUST00000186733]
[ENSMUST00000187968]
[ENSMUST00000188780]
[ENSMUST00000191064]
|
| AlphaFold |
B2RQG2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000088310
AA Change: L20P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000085650
Gene: ENSMUSG00000048874
AA Change: L20P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
337 |
344 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
651 |
660 |
N/A |
INTRINSIC |
|
PHD
|
697 |
748 |
3.82e-10 |
SMART |
|
low complexity region
|
847 |
859 |
N/A |
INTRINSIC |
|
low complexity region
|
876 |
887 |
N/A |
INTRINSIC |
|
TFS2M
|
908 |
1008 |
1.28e-47 |
SMART |
|
Pfam:SPOC
|
1188 |
1294 |
4.2e-26 |
PFAM |
|
low complexity region
|
1367 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1516 |
1529 |
N/A |
INTRINSIC |
|
low complexity region
|
1597 |
1620 |
N/A |
INTRINSIC |
|
low complexity region
|
1796 |
1811 |
N/A |
INTRINSIC |
|
low complexity region
|
1813 |
1846 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000186105
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000186733
AA Change: L20P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000139610
Gene: ENSMUSG00000048874
AA Change: L20P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
337 |
344 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
651 |
660 |
N/A |
INTRINSIC |
|
PHD
|
697 |
748 |
3.82e-10 |
SMART |
|
low complexity region
|
847 |
859 |
N/A |
INTRINSIC |
|
low complexity region
|
876 |
887 |
N/A |
INTRINSIC |
|
TFS2M
|
908 |
1008 |
1.28e-47 |
SMART |
|
Pfam:SPOC
|
1188 |
1294 |
4.2e-26 |
PFAM |
|
low complexity region
|
1367 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1516 |
1529 |
N/A |
INTRINSIC |
|
low complexity region
|
1597 |
1620 |
N/A |
INTRINSIC |
|
low complexity region
|
1796 |
1811 |
N/A |
INTRINSIC |
|
low complexity region
|
1813 |
1846 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000187600
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000187968
AA Change: L20P
PolyPhen 2
Score 0.933 (Sensitivity: 0.80; Specificity: 0.94)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000188780
AA Change: L20P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000140935
Gene: ENSMUSG00000048874
AA Change: L20P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
158 |
169 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000191064
AA Change: L20P
PolyPhen 2
Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000191245
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192050
|
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.7%
- 10x: 97.3%
- 20x: 94.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of a PHD finger-containing gene family. This gene may function as a transcription factor and may be involved in glioblastomas development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 70 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aass |
A |
T |
6: 23,114,985 (GRCm38) |
H181Q |
probably damaging |
Het |
| Abca13 |
T |
A |
11: 9,682,011 (GRCm38) |
L4977* |
probably null |
Het |
| Abca8a |
T |
A |
11: 110,028,190 (GRCm38) |
Y1550F |
probably damaging |
Het |
| Actr2 |
C |
T |
11: 20,072,584 (GRCm38) |
E296K |
probably benign |
Het |
| Agtpbp1 |
A |
T |
13: 59,533,939 (GRCm38) |
|
probably benign |
Het |
| Anks1b |
A |
C |
10: 90,071,125 (GRCm38) |
E268A |
probably damaging |
Het |
| Atp5s |
A |
T |
12: 69,741,810 (GRCm38) |
H161L |
probably benign |
Het |
| C1rl |
A |
G |
6: 124,508,506 (GRCm38) |
T279A |
probably benign |
Het |
| C5ar2 |
T |
C |
7: 16,237,601 (GRCm38) |
T134A |
probably benign |
Het |
| Cdkl3 |
G |
A |
11: 52,011,267 (GRCm38) |
R101Q |
probably damaging |
Het |
| Celsr2 |
A |
T |
3: 108,414,338 (GRCm38) |
F386Y |
probably benign |
Het |
| Chd1 |
C |
T |
17: 15,770,241 (GRCm38) |
P1685L |
probably damaging |
Het |
| Chrne |
G |
T |
11: 70,615,413 (GRCm38) |
H402Q |
probably benign |
Het |
| Clvs1 |
A |
G |
4: 9,282,003 (GRCm38) |
D149G |
possibly damaging |
Het |
| Cntnap5b |
T |
C |
1: 100,255,163 (GRCm38) |
Y620H |
probably benign |
Het |
| Col6a1 |
A |
G |
10: 76,713,624 (GRCm38) |
|
probably null |
Het |
| Cyp2d26 |
T |
A |
15: 82,790,233 (GRCm38) |
I483F |
probably benign |
Het |
| Dlx6 |
C |
T |
6: 6,863,665 (GRCm38) |
Q96* |
probably null |
Het |
| Eif1a |
T |
A |
18: 46,608,047 (GRCm38) |
N116K |
possibly damaging |
Het |
| Epb41l5 |
A |
T |
1: 119,549,954 (GRCm38) |
C696S |
probably benign |
Het |
| Exoc7 |
A |
G |
11: 116,295,248 (GRCm38) |
S376P |
possibly damaging |
Het |
| Fads1 |
C |
T |
19: 10,183,065 (GRCm38) |
P5L |
probably benign |
Het |
| G3bp1 |
T |
C |
11: 55,498,626 (GRCm38) |
F383L |
probably damaging |
Het |
| Gimap7 |
T |
C |
6: 48,723,723 (GRCm38) |
I81T |
probably damaging |
Het |
| Gtf2a1l |
T |
C |
17: 88,694,229 (GRCm38) |
V171A |
probably damaging |
Het |
| Hax1 |
A |
G |
3: 89,995,633 (GRCm38) |
S253P |
probably damaging |
Het |
| Hsd3b5 |
A |
T |
3: 98,619,355 (GRCm38) |
D258E |
probably damaging |
Het |
| Kcnb1 |
G |
T |
2: 167,106,267 (GRCm38) |
F220L |
probably damaging |
Het |
| Kif1a |
T |
A |
1: 93,019,898 (GRCm38) |
Y1708F |
probably damaging |
Het |
| Krt14 |
A |
T |
11: 100,204,264 (GRCm38) |
I379N |
probably damaging |
Het |
| Lpxn |
A |
G |
19: 12,804,037 (GRCm38) |
I40V |
probably benign |
Het |
| Lrp1 |
C |
T |
10: 127,553,362 (GRCm38) |
|
probably null |
Het |
| Lyst |
G |
A |
13: 13,634,930 (GRCm38) |
R395H |
probably benign |
Het |
| Mindy4 |
G |
A |
6: 55,318,286 (GRCm38) |
W737* |
probably null |
Het |
| Mki67 |
C |
A |
7: 135,701,043 (GRCm38) |
R754L |
probably benign |
Het |
| Morf4l1 |
A |
G |
9: 90,100,449 (GRCm38) |
V144A |
probably benign |
Het |
| Mvb12a |
T |
C |
8: 71,545,778 (GRCm38) |
S186P |
probably benign |
Het |
| Myrf |
G |
C |
19: 10,218,162 (GRCm38) |
T428S |
probably benign |
Het |
| Nipal1 |
A |
G |
5: 72,667,840 (GRCm38) |
N292S |
probably damaging |
Het |
| Nqo2 |
T |
G |
13: 33,972,478 (GRCm38) |
|
probably null |
Het |
| Olfr1532-ps1 |
A |
G |
7: 106,914,993 (GRCm38) |
K265R |
probably benign |
Het |
| Olfr294 |
T |
C |
7: 86,615,640 (GRCm38) |
Y335C |
probably damaging |
Het |
| Olfr807 |
C |
T |
10: 129,755,208 (GRCm38) |
V81I |
probably benign |
Het |
| Olfr994 |
A |
T |
2: 85,430,021 (GRCm38) |
N269K |
probably benign |
Het |
| Osbpl7 |
C |
A |
11: 97,060,524 (GRCm38) |
P507Q |
probably damaging |
Het |
| Pcdhb1 |
G |
A |
18: 37,267,422 (GRCm38) |
G809S |
probably benign |
Het |
| Pcm1 |
T |
C |
8: 41,282,683 (GRCm38) |
V846A |
probably damaging |
Het |
| Pih1d1 |
A |
G |
7: 45,157,617 (GRCm38) |
T58A |
probably damaging |
Het |
| Plekhn1 |
A |
G |
4: 156,223,564 (GRCm38) |
|
probably null |
Het |
| Plvap |
A |
T |
8: 71,506,882 (GRCm38) |
L422Q |
probably damaging |
Het |
| Polq |
C |
T |
16: 37,062,130 (GRCm38) |
A1273V |
probably benign |
Het |
| Prelid2 |
T |
A |
18: 41,935,224 (GRCm38) |
I51F |
probably damaging |
Het |
| Ptpn18 |
G |
A |
1: 34,462,702 (GRCm38) |
D8N |
probably damaging |
Het |
| Ptpra |
T |
A |
2: 130,518,991 (GRCm38) |
F190Y |
probably damaging |
Het |
| Pus7l |
A |
G |
15: 94,540,512 (GRCm38) |
S151P |
probably benign |
Het |
| Rsph6a |
G |
A |
7: 19,057,670 (GRCm38) |
D255N |
probably benign |
Het |
| Serpinb6c |
A |
T |
13: 33,899,305 (GRCm38) |
V42D |
probably damaging |
Het |
| Slc7a13 |
A |
G |
4: 19,818,866 (GRCm38) |
N22S |
probably benign |
Het |
| Snx5 |
G |
A |
2: 144,253,806 (GRCm38) |
R312C |
probably damaging |
Het |
| Stard9 |
T |
C |
2: 120,695,823 (GRCm38) |
S854P |
probably damaging |
Het |
| Syne2 |
AAGAG |
AAGAGAGAG |
12: 76,097,959 (GRCm38) |
|
probably null |
Het |
| Syne2 |
AGAGTGAG |
AGAGTGAGTGAG |
12: 76,097,960 (GRCm38) |
|
probably null |
Het |
| Tlr12 |
A |
G |
4: 128,616,291 (GRCm38) |
I722T |
probably benign |
Het |
| Tmem101 |
A |
T |
11: 102,155,866 (GRCm38) |
M59K |
possibly damaging |
Het |
| Trim34a |
C |
T |
7: 104,261,124 (GRCm38) |
R378C |
probably benign |
Het |
| Trim35 |
T |
A |
14: 66,309,125 (GRCm38) |
M447K |
probably benign |
Het |
| Trps1 |
C |
A |
15: 50,661,549 (GRCm38) |
S704I |
possibly damaging |
Het |
| Vmn1r231 |
T |
A |
17: 20,890,171 (GRCm38) |
S161C |
probably damaging |
Het |
| Vps13a |
A |
C |
19: 16,698,897 (GRCm38) |
N1237K |
probably damaging |
Het |
| Zfp619 |
G |
T |
7: 39,536,559 (GRCm38) |
C671F |
probably damaging |
Het |
|
| Other mutations in Phf3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00234:Phf3
|
APN |
1 |
30,811,847 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL00704:Phf3
|
APN |
1 |
30,804,838 (GRCm38) |
missense |
probably benign |
|
|
IGL01147:Phf3
|
APN |
1 |
30,804,169 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01360:Phf3
|
APN |
1 |
30,808,728 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01376:Phf3
|
APN |
1 |
30,830,485 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
IGL01396:Phf3
|
APN |
1 |
30,804,305 (GRCm38) |
nonsense |
probably null |
|
|
IGL01830:Phf3
|
APN |
1 |
30,814,067 (GRCm38) |
nonsense |
probably null |
|
|
IGL02108:Phf3
|
APN |
1 |
30,829,951 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02156:Phf3
|
APN |
1 |
30,808,778 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02576:Phf3
|
APN |
1 |
30,830,036 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL03031:Phf3
|
APN |
1 |
30,804,653 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03334:Phf3
|
APN |
1 |
30,805,729 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL03411:Phf3
|
APN |
1 |
30,804,401 (GRCm38) |
missense |
probably damaging |
1.00 |
|
FR4976:Phf3
|
UTSW |
1 |
30,805,023 (GRCm38) |
utr 3 prime |
probably benign |
|
|
PIT4458001:Phf3
|
UTSW |
1 |
30,816,541 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0037:Phf3
|
UTSW |
1 |
30,804,918 (GRCm38) |
missense |
probably benign |
0.03 |
|
R0052:Phf3
|
UTSW |
1 |
30,808,767 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0114:Phf3
|
UTSW |
1 |
30,805,443 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R0123:Phf3
|
UTSW |
1 |
30,805,065 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0225:Phf3
|
UTSW |
1 |
30,805,065 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0715:Phf3
|
UTSW |
1 |
30,811,838 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0835:Phf3
|
UTSW |
1 |
30,830,551 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1473:Phf3
|
UTSW |
1 |
30,805,940 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1522:Phf3
|
UTSW |
1 |
30,805,648 (GRCm38) |
missense |
probably benign |
0.05 |
|
R1549:Phf3
|
UTSW |
1 |
30,804,842 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1555:Phf3
|
UTSW |
1 |
30,805,877 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R1780:Phf3
|
UTSW |
1 |
30,811,942 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1789:Phf3
|
UTSW |
1 |
30,806,206 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1875:Phf3
|
UTSW |
1 |
30,830,623 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R1912:Phf3
|
UTSW |
1 |
30,804,345 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1957:Phf3
|
UTSW |
1 |
30,831,520 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2019:Phf3
|
UTSW |
1 |
30,811,847 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2259:Phf3
|
UTSW |
1 |
30,804,343 (GRCm38) |
missense |
probably benign |
0.20 |
|
R2305:Phf3
|
UTSW |
1 |
30,805,475 (GRCm38) |
nonsense |
probably null |
|
|
R2345:Phf3
|
UTSW |
1 |
30,805,351 (GRCm38) |
nonsense |
probably null |
|
|
R2424:Phf3
|
UTSW |
1 |
30,806,349 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2497:Phf3
|
UTSW |
1 |
30,830,014 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2504:Phf3
|
UTSW |
1 |
30,810,789 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3522:Phf3
|
UTSW |
1 |
30,805,603 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3816:Phf3
|
UTSW |
1 |
30,805,753 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4152:Phf3
|
UTSW |
1 |
30,831,458 (GRCm38) |
missense |
probably benign |
0.13 |
|
R4403:Phf3
|
UTSW |
1 |
30,804,409 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4658:Phf3
|
UTSW |
1 |
30,863,088 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4663:Phf3
|
UTSW |
1 |
30,821,215 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4669:Phf3
|
UTSW |
1 |
30,829,946 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4706:Phf3
|
UTSW |
1 |
30,805,606 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4757:Phf3
|
UTSW |
1 |
30,820,827 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4766:Phf3
|
UTSW |
1 |
30,813,939 (GRCm38) |
unclassified |
probably benign |
|
|
R4786:Phf3
|
UTSW |
1 |
30,816,557 (GRCm38) |
nonsense |
probably null |
|
|
R5107:Phf3
|
UTSW |
1 |
30,831,485 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5155:Phf3
|
UTSW |
1 |
30,824,376 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R5310:Phf3
|
UTSW |
1 |
30,803,806 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5823:Phf3
|
UTSW |
1 |
30,804,683 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5944:Phf3
|
UTSW |
1 |
30,820,704 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5979:Phf3
|
UTSW |
1 |
30,805,746 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6007:Phf3
|
UTSW |
1 |
30,804,345 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6024:Phf3
|
UTSW |
1 |
30,863,226 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6072:Phf3
|
UTSW |
1 |
30,830,688 (GRCm38) |
missense |
probably benign |
0.08 |
|
R6533:Phf3
|
UTSW |
1 |
30,806,318 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6649:Phf3
|
UTSW |
1 |
30,805,023 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R6653:Phf3
|
UTSW |
1 |
30,805,023 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R6852:Phf3
|
UTSW |
1 |
30,804,630 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R6855:Phf3
|
UTSW |
1 |
30,820,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6862:Phf3
|
UTSW |
1 |
30,813,982 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6930:Phf3
|
UTSW |
1 |
30,811,877 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7135:Phf3
|
UTSW |
1 |
30,831,109 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R7323:Phf3
|
UTSW |
1 |
30,813,130 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7352:Phf3
|
UTSW |
1 |
30,804,326 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R7455:Phf3
|
UTSW |
1 |
30,837,158 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7549:Phf3
|
UTSW |
1 |
30,831,475 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7609:Phf3
|
UTSW |
1 |
30,805,501 (GRCm38) |
missense |
probably benign |
0.05 |
|
R7720:Phf3
|
UTSW |
1 |
30,829,857 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7745:Phf3
|
UTSW |
1 |
30,804,224 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8134:Phf3
|
UTSW |
1 |
30,824,471 (GRCm38) |
missense |
unknown |
|
|
R8264:Phf3
|
UTSW |
1 |
30,831,057 (GRCm38) |
missense |
possibly damaging |
0.48 |
|
R8545:Phf3
|
UTSW |
1 |
30,824,310 (GRCm38) |
missense |
possibly damaging |
0.48 |
|
R8821:Phf3
|
UTSW |
1 |
30,821,266 (GRCm38) |
nonsense |
probably null |
|
|
R8831:Phf3
|
UTSW |
1 |
30,821,266 (GRCm38) |
nonsense |
probably null |
|
|
R8873:Phf3
|
UTSW |
1 |
30,804,692 (GRCm38) |
missense |
possibly damaging |
0.74 |
|
R9101:Phf3
|
UTSW |
1 |
30,803,945 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R9402:Phf3
|
UTSW |
1 |
30,811,847 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9426:Phf3
|
UTSW |
1 |
30,831,544 (GRCm38) |
nonsense |
probably null |
|
|
R9594:Phf3
|
UTSW |
1 |
30,829,922 (GRCm38) |
missense |
probably benign |
0.07 |
|
R9707:Phf3
|
UTSW |
1 |
30,829,842 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9803:Phf3
|
UTSW |
1 |
30,830,791 (GRCm38) |
missense |
probably benign |
0.16 |
|
Z1177:Phf3
|
UTSW |
1 |
30,811,968 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
Z1177:Phf3
|
UTSW |
1 |
30,805,051 (GRCm38) |
missense |
unknown |
|
|
Z1177:Phf3
|
UTSW |
1 |
30,804,295 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGATCATTGCTATCCAAAACAGGCAAAC -3'
(R):5'- CATGTGTGTAAGTCCCACATAACTCACTAAAA -3'
Sequencing Primer
(F):5'- TATCCAAAACAGGCAAACAGAACTG -3'
(R):5'- GTGGACTCACTGTAAAAGCATTG -3'
|
| Posted On |
2013-10-16 |
Incidental Mutation