Incidental Mutation 'R0848:Anks1b'
| ID |
77433 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Anks1b
|
| Ensembl Gene |
ENSMUSG00000058589 |
| Gene Name |
ankyrin repeat and sterile alpha motif domain containing 1B |
| Synonyms |
C030032C09Rik, Gm10937, AIDA-1b, LOC380650, E530015N03Rik |
| MMRRC Submission |
039027-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0848 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
89709371-90809162 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 89906987 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Alanine
at position 268
(E268A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138539
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000099368]
[ENSMUST00000182907]
[ENSMUST00000182936]
[ENSMUST00000183156]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000099368
AA Change: E268A
PolyPhen 2
Score 0.473 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000096968
Gene: ENSMUSG00000058589
AA Change: E268A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
21 |
46 |
N/A |
INTRINSIC |
|
ANK
|
58 |
87 |
1.88e-5 |
SMART |
|
ANK
|
91 |
123 |
3.13e-2 |
SMART |
|
ANK
|
127 |
156 |
6.92e-4 |
SMART |
|
ANK
|
160 |
189 |
3.08e-1 |
SMART |
|
ANK
|
193 |
222 |
1.43e-5 |
SMART |
|
ANK
|
225 |
254 |
4.75e-2 |
SMART |
|
low complexity region
|
498 |
513 |
N/A |
INTRINSIC |
|
low complexity region
|
551 |
577 |
N/A |
INTRINSIC |
|
low complexity region
|
659 |
670 |
N/A |
INTRINSIC |
|
SAM
|
806 |
875 |
2.06e-19 |
SMART |
|
SAM
|
880 |
931 |
4.44e-1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000182907
|
| SMART Domains |
Protein: ENSMUSP00000138614
Gene: ENSMUSG00000058589
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
21 |
45 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000182936
|
| SMART Domains |
Protein: ENSMUSP00000138209
Gene: ENSMUSG00000058589
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
21 |
46 |
N/A |
INTRINSIC |
|
ANK
|
58 |
87 |
1.88e-5 |
SMART |
|
ANK
|
91 |
123 |
3.13e-2 |
SMART |
|
ANK
|
127 |
156 |
6.92e-4 |
SMART |
|
ANK
|
160 |
189 |
3.08e-1 |
SMART |
|
ANK
|
193 |
222 |
1.43e-5 |
SMART |
|
ANK
|
225 |
254 |
5.03e2 |
SMART |
|
low complexity region
|
464 |
479 |
N/A |
INTRINSIC |
|
low complexity region
|
517 |
543 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183012
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000183109
AA Change: E5A
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000183156
AA Change: E268A
PolyPhen 2
Score 0.986 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000138539
Gene: ENSMUSG00000058589
AA Change: E268A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
21 |
46 |
N/A |
INTRINSIC |
|
ANK
|
58 |
87 |
1.88e-5 |
SMART |
|
ANK
|
91 |
123 |
3.13e-2 |
SMART |
|
ANK
|
127 |
156 |
6.92e-4 |
SMART |
|
ANK
|
160 |
189 |
3.08e-1 |
SMART |
|
ANK
|
193 |
222 |
1.43e-5 |
SMART |
|
ANK
|
225 |
254 |
4.75e-2 |
SMART |
|
low complexity region
|
498 |
513 |
N/A |
INTRINSIC |
|
low complexity region
|
551 |
577 |
N/A |
INTRINSIC |
|
low complexity region
|
659 |
670 |
N/A |
INTRINSIC |
|
SAM
|
806 |
875 |
2.06e-19 |
SMART |
|
SAM
|
880 |
948 |
5.66e-17 |
SMART |
|
low complexity region
|
968 |
983 |
N/A |
INTRINSIC |
|
PTB
|
1056 |
1194 |
2.94e-38 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.7%
- 10x: 97.3%
- 20x: 94.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011]
PHENOTYPE: Mice homozygous for a conditional allele activated in neurons alters hippocampal synaptic transmission. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 70 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aass |
A |
T |
6: 23,114,984 (GRCm39) |
H181Q |
probably damaging |
Het |
| Abca13 |
T |
A |
11: 9,632,011 (GRCm39) |
L4977* |
probably null |
Het |
| Abca8a |
T |
A |
11: 109,919,016 (GRCm39) |
Y1550F |
probably damaging |
Het |
| Actr2 |
C |
T |
11: 20,022,584 (GRCm39) |
E296K |
probably benign |
Het |
| Agtpbp1 |
A |
T |
13: 59,681,753 (GRCm39) |
|
probably benign |
Het |
| C1rl |
A |
G |
6: 124,485,465 (GRCm39) |
T279A |
probably benign |
Het |
| C5ar2 |
T |
C |
7: 15,971,526 (GRCm39) |
T134A |
probably benign |
Het |
| Cdkl3 |
G |
A |
11: 51,902,094 (GRCm39) |
R101Q |
probably damaging |
Het |
| Celsr2 |
A |
T |
3: 108,321,654 (GRCm39) |
F386Y |
probably benign |
Het |
| Chd1 |
C |
T |
17: 15,990,503 (GRCm39) |
P1685L |
probably damaging |
Het |
| Chrne |
G |
T |
11: 70,506,239 (GRCm39) |
H402Q |
probably benign |
Het |
| Clvs1 |
A |
G |
4: 9,282,003 (GRCm39) |
D149G |
possibly damaging |
Het |
| Cntnap5b |
T |
C |
1: 100,182,888 (GRCm39) |
Y620H |
probably benign |
Het |
| Col6a1 |
A |
G |
10: 76,549,458 (GRCm39) |
|
probably null |
Het |
| Cyp2d26 |
T |
A |
15: 82,674,434 (GRCm39) |
I483F |
probably benign |
Het |
| Dlx6 |
C |
T |
6: 6,863,665 (GRCm39) |
Q96* |
probably null |
Het |
| Dmac2l |
A |
T |
12: 69,788,584 (GRCm39) |
H161L |
probably benign |
Het |
| Eif1a |
T |
A |
18: 46,741,114 (GRCm39) |
N116K |
possibly damaging |
Het |
| Epb41l5 |
A |
T |
1: 119,477,684 (GRCm39) |
C696S |
probably benign |
Het |
| Exoc7 |
A |
G |
11: 116,186,074 (GRCm39) |
S376P |
possibly damaging |
Het |
| Fads1 |
C |
T |
19: 10,160,429 (GRCm39) |
P5L |
probably benign |
Het |
| G3bp1 |
T |
C |
11: 55,389,452 (GRCm39) |
F383L |
probably damaging |
Het |
| Gimap7 |
T |
C |
6: 48,700,657 (GRCm39) |
I81T |
probably damaging |
Het |
| Gtf2a1l |
T |
C |
17: 89,001,657 (GRCm39) |
V171A |
probably damaging |
Het |
| Hax1 |
A |
G |
3: 89,902,940 (GRCm39) |
S253P |
probably damaging |
Het |
| Hsd3b5 |
A |
T |
3: 98,526,671 (GRCm39) |
D258E |
probably damaging |
Het |
| Kcnb1 |
G |
T |
2: 166,948,187 (GRCm39) |
F220L |
probably damaging |
Het |
| Kif1a |
T |
A |
1: 92,947,620 (GRCm39) |
Y1708F |
probably damaging |
Het |
| Krt14 |
A |
T |
11: 100,095,090 (GRCm39) |
I379N |
probably damaging |
Het |
| Lpxn |
A |
G |
19: 12,781,401 (GRCm39) |
I40V |
probably benign |
Het |
| Lrp1 |
C |
T |
10: 127,389,231 (GRCm39) |
|
probably null |
Het |
| Lyst |
G |
A |
13: 13,809,515 (GRCm39) |
R395H |
probably benign |
Het |
| Mindy4 |
G |
A |
6: 55,295,271 (GRCm39) |
W737* |
probably null |
Het |
| Mki67 |
C |
A |
7: 135,302,772 (GRCm39) |
R754L |
probably benign |
Het |
| Morf4l1 |
A |
G |
9: 89,982,502 (GRCm39) |
V144A |
probably benign |
Het |
| Mvb12a |
T |
C |
8: 71,998,422 (GRCm39) |
S186P |
probably benign |
Het |
| Myrf |
G |
C |
19: 10,195,526 (GRCm39) |
T428S |
probably benign |
Het |
| Nipal1 |
A |
G |
5: 72,825,183 (GRCm39) |
N292S |
probably damaging |
Het |
| Nqo2 |
T |
G |
13: 34,156,461 (GRCm39) |
|
probably null |
Het |
| Or14a256 |
T |
C |
7: 86,264,848 (GRCm39) |
Y335C |
probably damaging |
Het |
| Or2d3b |
A |
G |
7: 106,514,200 (GRCm39) |
K265R |
probably benign |
Het |
| Or5ak24 |
A |
T |
2: 85,260,365 (GRCm39) |
N269K |
probably benign |
Het |
| Or6c214 |
C |
T |
10: 129,591,077 (GRCm39) |
V81I |
probably benign |
Het |
| Osbpl7 |
C |
A |
11: 96,951,350 (GRCm39) |
P507Q |
probably damaging |
Het |
| Pcdhb1 |
G |
A |
18: 37,400,475 (GRCm39) |
G809S |
probably benign |
Het |
| Pcm1 |
T |
C |
8: 41,735,720 (GRCm39) |
V846A |
probably damaging |
Het |
| Phf3 |
A |
G |
1: 30,902,253 (GRCm39) |
L20P |
probably damaging |
Het |
| Pih1d1 |
A |
G |
7: 44,807,041 (GRCm39) |
T58A |
probably damaging |
Het |
| Plekhn1 |
A |
G |
4: 156,308,021 (GRCm39) |
|
probably null |
Het |
| Plvap |
A |
T |
8: 71,959,526 (GRCm39) |
L422Q |
probably damaging |
Het |
| Polq |
C |
T |
16: 36,882,492 (GRCm39) |
A1273V |
probably benign |
Het |
| Prelid2 |
T |
A |
18: 42,068,289 (GRCm39) |
I51F |
probably damaging |
Het |
| Ptpn18 |
G |
A |
1: 34,501,783 (GRCm39) |
D8N |
probably damaging |
Het |
| Ptpra |
T |
A |
2: 130,360,911 (GRCm39) |
F190Y |
probably damaging |
Het |
| Pus7l |
A |
G |
15: 94,438,393 (GRCm39) |
S151P |
probably benign |
Het |
| Rsph6a |
G |
A |
7: 18,791,595 (GRCm39) |
D255N |
probably benign |
Het |
| Serpinb6c |
A |
T |
13: 34,083,288 (GRCm39) |
V42D |
probably damaging |
Het |
| Slc7a13 |
A |
G |
4: 19,818,866 (GRCm39) |
N22S |
probably benign |
Het |
| Snx5 |
G |
A |
2: 144,095,726 (GRCm39) |
R312C |
probably damaging |
Het |
| Stard9 |
T |
C |
2: 120,526,304 (GRCm39) |
S854P |
probably damaging |
Het |
| Syne2 |
AAGAG |
AAGAGAGAG |
12: 76,144,733 (GRCm39) |
|
probably null |
Het |
| Syne2 |
AGAGTGAG |
AGAGTGAGTGAG |
12: 76,144,734 (GRCm39) |
|
probably null |
Het |
| Tlr12 |
A |
G |
4: 128,510,084 (GRCm39) |
I722T |
probably benign |
Het |
| Tmem101 |
A |
T |
11: 102,046,692 (GRCm39) |
M59K |
possibly damaging |
Het |
| Trim34a |
C |
T |
7: 103,910,331 (GRCm39) |
R378C |
probably benign |
Het |
| Trim35 |
T |
A |
14: 66,546,574 (GRCm39) |
M447K |
probably benign |
Het |
| Trps1 |
C |
A |
15: 50,524,945 (GRCm39) |
S704I |
possibly damaging |
Het |
| Vmn1r231 |
T |
A |
17: 21,110,433 (GRCm39) |
S161C |
probably damaging |
Het |
| Vps13a |
A |
C |
19: 16,676,261 (GRCm39) |
N1237K |
probably damaging |
Het |
| Zfp619 |
G |
T |
7: 39,185,983 (GRCm39) |
C671F |
probably damaging |
Het |
|
| Other mutations in Anks1b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01669:Anks1b
|
APN |
10 |
90,733,100 (GRCm39) |
splice site |
probably benign |
|
|
IGL01890:Anks1b
|
APN |
10 |
90,480,389 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01966:Anks1b
|
APN |
10 |
90,730,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02176:Anks1b
|
APN |
10 |
89,878,530 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02205:Anks1b
|
APN |
10 |
89,906,956 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02465:Anks1b
|
APN |
10 |
89,999,127 (GRCm39) |
nonsense |
probably null |
|
|
IGL02534:Anks1b
|
APN |
10 |
90,730,979 (GRCm39) |
missense |
probably benign |
0.45 |
|
IGL02554:Anks1b
|
APN |
10 |
90,757,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02820:Anks1b
|
APN |
10 |
89,912,921 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03164:Anks1b
|
APN |
10 |
89,878,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0096:Anks1b
|
UTSW |
10 |
89,909,924 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0096:Anks1b
|
UTSW |
10 |
89,909,924 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0482:Anks1b
|
UTSW |
10 |
90,195,057 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0542:Anks1b
|
UTSW |
10 |
89,909,829 (GRCm39) |
splice site |
probably benign |
|
|
R1056:Anks1b
|
UTSW |
10 |
90,757,291 (GRCm39) |
splice site |
probably null |
|
|
R1398:Anks1b
|
UTSW |
10 |
89,885,891 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1446:Anks1b
|
UTSW |
10 |
90,346,935 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1548:Anks1b
|
UTSW |
10 |
89,885,847 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1551:Anks1b
|
UTSW |
10 |
89,912,843 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1607:Anks1b
|
UTSW |
10 |
89,878,410 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1667:Anks1b
|
UTSW |
10 |
90,347,046 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1701:Anks1b
|
UTSW |
10 |
89,885,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1843:Anks1b
|
UTSW |
10 |
90,348,751 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1899:Anks1b
|
UTSW |
10 |
90,096,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1957:Anks1b
|
UTSW |
10 |
89,885,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2036:Anks1b
|
UTSW |
10 |
90,805,715 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2279:Anks1b
|
UTSW |
10 |
89,885,958 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2280:Anks1b
|
UTSW |
10 |
90,802,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2937:Anks1b
|
UTSW |
10 |
89,912,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3739:Anks1b
|
UTSW |
10 |
89,869,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4061:Anks1b
|
UTSW |
10 |
90,143,484 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4459:Anks1b
|
UTSW |
10 |
90,346,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4479:Anks1b
|
UTSW |
10 |
89,885,754 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4510:Anks1b
|
UTSW |
10 |
90,346,652 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4511:Anks1b
|
UTSW |
10 |
90,346,652 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4780:Anks1b
|
UTSW |
10 |
89,709,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4785:Anks1b
|
UTSW |
10 |
90,750,612 (GRCm39) |
missense |
probably null |
0.88 |
|
R4790:Anks1b
|
UTSW |
10 |
89,999,137 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5012:Anks1b
|
UTSW |
10 |
90,194,999 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5400:Anks1b
|
UTSW |
10 |
90,348,686 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5586:Anks1b
|
UTSW |
10 |
89,912,926 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5687:Anks1b
|
UTSW |
10 |
90,750,573 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5899:Anks1b
|
UTSW |
10 |
90,759,379 (GRCm39) |
splice site |
probably null |
|
|
R5917:Anks1b
|
UTSW |
10 |
90,412,803 (GRCm39) |
intron |
probably benign |
|
|
R5999:Anks1b
|
UTSW |
10 |
90,194,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6080:Anks1b
|
UTSW |
10 |
90,802,211 (GRCm39) |
nonsense |
probably null |
|
|
R6216:Anks1b
|
UTSW |
10 |
90,096,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6265:Anks1b
|
UTSW |
10 |
90,777,362 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6298:Anks1b
|
UTSW |
10 |
90,516,699 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6337:Anks1b
|
UTSW |
10 |
90,757,158 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6522:Anks1b
|
UTSW |
10 |
90,733,189 (GRCm39) |
intron |
probably benign |
|
|
R6843:Anks1b
|
UTSW |
10 |
90,784,460 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6852:Anks1b
|
UTSW |
10 |
90,096,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6933:Anks1b
|
UTSW |
10 |
89,905,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7114:Anks1b
|
UTSW |
10 |
90,143,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7211:Anks1b
|
UTSW |
10 |
90,346,932 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7241:Anks1b
|
UTSW |
10 |
90,348,699 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7264:Anks1b
|
UTSW |
10 |
90,348,732 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7325:Anks1b
|
UTSW |
10 |
90,777,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7392:Anks1b
|
UTSW |
10 |
90,516,648 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R7578:Anks1b
|
UTSW |
10 |
89,885,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7604:Anks1b
|
UTSW |
10 |
90,096,708 (GRCm39) |
splice site |
probably null |
|
|
R7633:Anks1b
|
UTSW |
10 |
90,784,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7881:Anks1b
|
UTSW |
10 |
90,802,880 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7910:Anks1b
|
UTSW |
10 |
90,516,654 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7941:Anks1b
|
UTSW |
10 |
90,413,017 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8045:Anks1b
|
UTSW |
10 |
90,516,722 (GRCm39) |
missense |
probably benign |
|
|
R8146:Anks1b
|
UTSW |
10 |
90,143,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8176:Anks1b
|
UTSW |
10 |
89,905,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8535:Anks1b
|
UTSW |
10 |
90,784,493 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8681:Anks1b
|
UTSW |
10 |
89,885,868 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9300:Anks1b
|
UTSW |
10 |
90,412,966 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9469:Anks1b
|
UTSW |
10 |
90,733,205 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R9541:Anks1b
|
UTSW |
10 |
90,412,947 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9550:Anks1b
|
UTSW |
10 |
90,412,360 (GRCm39) |
start codon destroyed |
probably null |
|
|
R9653:Anks1b
|
UTSW |
10 |
90,346,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF004:Anks1b
|
UTSW |
10 |
89,869,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF008:Anks1b
|
UTSW |
10 |
89,869,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF017:Anks1b
|
UTSW |
10 |
89,869,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF018:Anks1b
|
UTSW |
10 |
89,869,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF023:Anks1b
|
UTSW |
10 |
89,869,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0064:Anks1b
|
UTSW |
10 |
90,348,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCTTCAGTGCTTGGCCTATATGC -3'
(R):5'- AAGGCTTCAGTGTCTCTCGCTTG -3'
Sequencing Primer
(F):5'- GCGTTTGAAATTAGAACGGTTAC -3'
(R):5'- TGTGCCAGGTGATGATATACCAC -3'
|
| Posted On |
2013-10-16 |
Incidental Mutation