Incidental Mutation 'R0834:Ift172'
| ID |
77716 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ift172
|
| Ensembl Gene |
ENSMUSG00000038564 |
| Gene Name |
intraflagellar transport 172 |
| Synonyms |
4930553F24Rik, wim, avc1 |
| MMRRC Submission |
039013-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0834 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
31410623-31448458 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 31414715 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Arginine
at position 1395
(H1395R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000049335
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041565]
[ENSMUST00000054829]
[ENSMUST00000201937]
[ENSMUST00000201625]
|
| AlphaFold |
Q6VH22 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041565
AA Change: H1395R
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000049335
Gene: ENSMUSG00000038564
AA Change: H1395R
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
2 |
44 |
6e-3 |
SMART |
|
WD40
|
55 |
94 |
2.22e0 |
SMART |
|
WD40
|
102 |
139 |
1.23e2 |
SMART |
|
WD40
|
141 |
180 |
4.6e0 |
SMART |
|
WD40
|
186 |
223 |
3.3e1 |
SMART |
|
WD40
|
225 |
267 |
4.42e1 |
SMART |
|
WD40
|
279 |
314 |
1.03e1 |
SMART |
|
Blast:WD40
|
516 |
550 |
5e-13 |
BLAST |
|
low complexity region
|
573 |
588 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
625 |
1026 |
1.7e-10 |
PROSPERO |
|
Blast:TPR
|
1029 |
1062 |
2e-13 |
BLAST |
|
low complexity region
|
1077 |
1091 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1101 |
1498 |
1.7e-10 |
PROSPERO |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000054829
|
| SMART Domains |
Protein: ENSMUSP00000060414
Gene: ENSMUSG00000029149
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BCLP
|
19 |
211 |
8.6e-80 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201057
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201333
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201393
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201426
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201565
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201953
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000202384
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000202007
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000202560
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201672
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201697
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000201937
|
| SMART Domains |
Protein: ENSMUSP00000144464
Gene: ENSMUSG00000029149
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BCLP
|
19 |
206 |
1.8e-74 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000201625
|
| SMART Domains |
Protein: ENSMUSP00000144052
Gene: ENSMUSG00000029149
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BCLP
|
19 |
206 |
1.8e-74 |
PFAM |
|
| Meta Mutation Damage Score |
0.0609 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.9%
- 10x: 97.7%
- 20x: 95.7%
|
| Validation Efficiency |
100% (86/86) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a subunit of the intraflagellar transport subcomplex IFT-B. Subcomplexes IFT-A and IFT-B are necessary for ciliary assembly and maintenance. Mutations in this gene have been associated with skeletal ciliopathies, with or without polydactyly, such as such short-rib thoracic dysplasias 1, 9 or 10. [provided by RefSeq, Mar 2014]
PHENOTYPE: Mice homozygous for disruptions in this gene display embryonic lethality during organogenesis, neural tube defects, and developmental patterning abnormalities. Mice homozygous for a conditional allele activated in the early limb bud exhibit polydactyly and short limbs. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Add2 |
A |
T |
6: 86,063,899 (GRCm39) |
E66V |
probably damaging |
Het |
| Aldh1a3 |
T |
C |
7: 66,062,658 (GRCm39) |
I156V |
probably benign |
Het |
| Ang4 |
T |
A |
14: 52,001,725 (GRCm39) |
K74N |
probably benign |
Het |
| Arcn1 |
A |
T |
9: 44,670,172 (GRCm39) |
|
probably benign |
Het |
| Arhgef33 |
T |
A |
17: 80,655,026 (GRCm39) |
|
probably benign |
Het |
| Atn1 |
A |
G |
6: 124,720,188 (GRCm39) |
|
probably benign |
Het |
| Bmal2 |
A |
G |
6: 146,724,185 (GRCm39) |
H359R |
probably damaging |
Het |
| Bmerb1 |
T |
C |
16: 13,911,795 (GRCm39) |
L47P |
probably damaging |
Het |
| Brip1 |
T |
C |
11: 86,083,653 (GRCm39) |
T123A |
probably benign |
Het |
| Camkv |
A |
G |
9: 107,823,045 (GRCm39) |
Y95C |
probably damaging |
Het |
| Cdk12 |
T |
A |
11: 98,095,211 (GRCm39) |
S340T |
probably benign |
Het |
| Ckap2l |
G |
A |
2: 129,138,224 (GRCm39) |
|
probably benign |
Het |
| Clmn |
A |
T |
12: 104,738,085 (GRCm39) |
L1042Q |
probably damaging |
Het |
| Clmn |
G |
T |
12: 104,738,086 (GRCm39) |
L1042M |
probably damaging |
Het |
| Cluh |
T |
C |
11: 74,554,631 (GRCm39) |
V737A |
probably benign |
Het |
| Cpne8 |
A |
G |
15: 90,424,462 (GRCm39) |
V309A |
probably benign |
Het |
| Cpxm2 |
T |
A |
7: 131,756,342 (GRCm39) |
|
probably benign |
Het |
| Csmd3 |
A |
T |
15: 47,747,073 (GRCm39) |
|
probably benign |
Het |
| Ctr9 |
T |
A |
7: 110,650,159 (GRCm39) |
S818T |
probably benign |
Het |
| Cyp26a1 |
C |
T |
19: 37,688,405 (GRCm39) |
A309V |
probably damaging |
Het |
| Dbndd2 |
C |
T |
2: 164,332,122 (GRCm39) |
T115I |
possibly damaging |
Het |
| Dhcr7 |
A |
G |
7: 143,394,964 (GRCm39) |
N157S |
probably benign |
Het |
| Dlx2 |
C |
A |
2: 71,375,859 (GRCm39) |
V155F |
probably damaging |
Het |
| Duox1 |
A |
T |
2: 122,176,982 (GRCm39) |
I1470F |
probably damaging |
Het |
| Esrrb |
A |
T |
12: 86,517,071 (GRCm39) |
I68F |
probably benign |
Het |
| Fhod3 |
T |
A |
18: 25,248,862 (GRCm39) |
L1347* |
probably null |
Het |
| Fip1l1 |
T |
C |
5: 74,755,721 (GRCm39) |
|
probably benign |
Het |
| Frem3 |
A |
G |
8: 81,413,637 (GRCm39) |
Y1966C |
probably damaging |
Het |
| Gatd3a |
T |
C |
10: 77,998,539 (GRCm39) |
D229G |
probably damaging |
Het |
| Ggt5 |
C |
T |
10: 75,440,604 (GRCm39) |
R242C |
possibly damaging |
Het |
| Gm14496 |
G |
A |
2: 181,637,480 (GRCm39) |
V185I |
probably benign |
Het |
| Gnptab |
T |
C |
10: 88,265,814 (GRCm39) |
V409A |
probably damaging |
Het |
| Gramd1a |
A |
G |
7: 30,837,589 (GRCm39) |
F390S |
possibly damaging |
Het |
| Helz2 |
A |
G |
2: 180,872,570 (GRCm39) |
S2477P |
probably damaging |
Het |
| Hsd17b3 |
T |
C |
13: 64,236,936 (GRCm39) |
K3E |
probably benign |
Het |
| Jam2 |
T |
A |
16: 84,609,855 (GRCm39) |
C180S |
probably damaging |
Het |
| Kalrn |
A |
C |
16: 33,870,289 (GRCm39) |
S160A |
possibly damaging |
Het |
| Kcnk3 |
T |
C |
5: 30,779,979 (GRCm39) |
I343T |
probably damaging |
Het |
| Kif13a |
T |
C |
13: 46,967,712 (GRCm39) |
E334G |
probably damaging |
Het |
| Klhl41 |
A |
G |
2: 69,508,491 (GRCm39) |
K482E |
possibly damaging |
Het |
| Lig3 |
A |
G |
11: 82,689,113 (GRCm39) |
E794G |
probably damaging |
Het |
| Myh13 |
T |
C |
11: 67,240,436 (GRCm39) |
M780T |
possibly damaging |
Het |
| Ndst2 |
A |
G |
14: 20,779,761 (GRCm39) |
Y160H |
probably damaging |
Het |
| Ndufb10 |
T |
C |
17: 24,941,648 (GRCm39) |
M90V |
probably damaging |
Het |
| Obscn |
T |
C |
11: 59,024,104 (GRCm39) |
K522R |
probably benign |
Het |
| Olfml2b |
T |
C |
1: 170,475,413 (GRCm39) |
S113P |
probably benign |
Het |
| Or14a257 |
T |
A |
7: 86,138,698 (GRCm39) |
E20D |
probably benign |
Het |
| Or4a78 |
A |
G |
2: 89,497,423 (GRCm39) |
I269T |
probably benign |
Het |
| Or4d10b |
T |
A |
19: 12,036,979 (GRCm39) |
M46L |
probably benign |
Het |
| Or51v14 |
T |
C |
7: 103,261,444 (GRCm39) |
T39A |
probably benign |
Het |
| Or6k2 |
T |
A |
1: 173,986,930 (GRCm39) |
M197K |
possibly damaging |
Het |
| Parg |
T |
C |
14: 31,936,511 (GRCm39) |
|
probably benign |
Het |
| Pde7a |
C |
T |
3: 19,284,482 (GRCm39) |
C367Y |
probably damaging |
Het |
| Pigr |
T |
A |
1: 130,772,281 (GRCm39) |
C166* |
probably null |
Het |
| Pip4k2c |
A |
T |
10: 127,036,704 (GRCm39) |
|
probably benign |
Het |
| Ppp1r16a |
C |
T |
15: 76,577,869 (GRCm39) |
Q328* |
probably null |
Het |
| Prkd2 |
A |
T |
7: 16,599,602 (GRCm39) |
|
probably benign |
Het |
| Ptprt |
G |
T |
2: 161,654,059 (GRCm39) |
|
probably null |
Het |
| Rapgef5 |
C |
T |
12: 117,610,741 (GRCm39) |
|
probably benign |
Het |
| Retreg1 |
T |
C |
15: 25,971,756 (GRCm39) |
L356P |
probably benign |
Het |
| Rigi |
T |
A |
4: 40,239,596 (GRCm39) |
E34V |
possibly damaging |
Het |
| Rnf43 |
A |
G |
11: 87,622,077 (GRCm39) |
T393A |
probably benign |
Het |
| Samd3 |
T |
C |
10: 26,147,725 (GRCm39) |
S467P |
probably benign |
Het |
| Scarf1 |
C |
A |
11: 75,405,229 (GRCm39) |
C89* |
probably null |
Het |
| Sdk1 |
T |
C |
5: 141,227,779 (GRCm39) |
L59S |
probably benign |
Het |
| Sgca |
C |
T |
11: 94,861,512 (GRCm39) |
W244* |
probably null |
Het |
| Sh3d21 |
T |
C |
4: 126,045,065 (GRCm39) |
K538R |
probably benign |
Het |
| Smyd4 |
T |
A |
11: 75,281,958 (GRCm39) |
L477Q |
possibly damaging |
Het |
| Sra1 |
A |
G |
18: 36,801,829 (GRCm39) |
M87T |
probably benign |
Het |
| Ssh2 |
T |
C |
11: 77,328,459 (GRCm39) |
Y336H |
possibly damaging |
Het |
| Steap1 |
T |
C |
5: 5,790,357 (GRCm39) |
Y197C |
probably damaging |
Het |
| Strn3 |
A |
G |
12: 51,673,879 (GRCm39) |
|
probably benign |
Het |
| Tgm3 |
A |
G |
2: 129,868,677 (GRCm39) |
T205A |
probably benign |
Het |
| Tll2 |
G |
A |
19: 41,101,512 (GRCm39) |
T374I |
probably damaging |
Het |
| Tmem63b |
C |
A |
17: 45,971,870 (GRCm39) |
D782Y |
possibly damaging |
Het |
| Trim10 |
G |
A |
17: 37,183,283 (GRCm39) |
S193N |
probably benign |
Het |
| Ttf1 |
A |
T |
2: 28,963,962 (GRCm39) |
K613* |
probably null |
Het |
| Tube1 |
T |
A |
10: 39,010,168 (GRCm39) |
|
probably null |
Het |
| Uimc1 |
T |
A |
13: 55,224,222 (GRCm39) |
|
probably null |
Het |
| Wwp2 |
G |
T |
8: 108,283,428 (GRCm39) |
|
probably benign |
Het |
| Zfp101 |
C |
T |
17: 33,601,418 (GRCm39) |
V113I |
probably benign |
Het |
| Zfp292 |
T |
C |
4: 34,809,114 (GRCm39) |
D1310G |
probably benign |
Het |
| Zfp575 |
A |
T |
7: 24,285,245 (GRCm39) |
L132H |
probably damaging |
Het |
| Zmym2 |
T |
C |
14: 57,194,420 (GRCm39) |
F1226S |
probably damaging |
Het |
| Zswim6 |
A |
C |
13: 107,862,989 (GRCm39) |
|
noncoding transcript |
Het |
|
| Other mutations in Ift172 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Ift172
|
APN |
5 |
31,433,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01399:Ift172
|
APN |
5 |
31,423,592 (GRCm39) |
missense |
probably benign |
|
|
IGL01405:Ift172
|
APN |
5 |
31,419,196 (GRCm39) |
nonsense |
probably null |
|
|
IGL01562:Ift172
|
APN |
5 |
31,424,591 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01758:Ift172
|
APN |
5 |
31,438,058 (GRCm39) |
missense |
probably benign |
|
|
IGL01792:Ift172
|
APN |
5 |
31,434,215 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01830:Ift172
|
APN |
5 |
31,442,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01839:Ift172
|
APN |
5 |
31,423,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02007:Ift172
|
APN |
5 |
31,443,948 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02172:Ift172
|
APN |
5 |
31,438,681 (GRCm39) |
splice site |
probably benign |
|
|
IGL02190:Ift172
|
APN |
5 |
31,411,802 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL02334:Ift172
|
APN |
5 |
31,440,402 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02486:Ift172
|
APN |
5 |
31,414,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02517:Ift172
|
APN |
5 |
31,410,992 (GRCm39) |
splice site |
probably null |
|
|
IGL02571:Ift172
|
APN |
5 |
31,415,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02626:Ift172
|
APN |
5 |
31,421,840 (GRCm39) |
missense |
probably benign |
|
|
IGL03183:Ift172
|
APN |
5 |
31,429,348 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL03277:Ift172
|
APN |
5 |
31,424,642 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03349:Ift172
|
APN |
5 |
31,441,474 (GRCm39) |
missense |
probably benign |
0.05 |
|
ostinato
|
UTSW |
5 |
31,434,284 (GRCm39) |
missense |
probably benign |
0.10 |
|
pushback
|
UTSW |
5 |
31,444,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P0042:Ift172
|
UTSW |
5 |
31,418,799 (GRCm39) |
missense |
probably benign |
0.35 |
|
PIT4802001:Ift172
|
UTSW |
5 |
31,442,610 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0153:Ift172
|
UTSW |
5 |
31,417,968 (GRCm39) |
missense |
probably benign |
|
|
R0328:Ift172
|
UTSW |
5 |
31,421,195 (GRCm39) |
nonsense |
probably null |
|
|
R0357:Ift172
|
UTSW |
5 |
31,415,244 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R0369:Ift172
|
UTSW |
5 |
31,410,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0391:Ift172
|
UTSW |
5 |
31,444,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0512:Ift172
|
UTSW |
5 |
31,442,821 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0546:Ift172
|
UTSW |
5 |
31,414,945 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0553:Ift172
|
UTSW |
5 |
31,433,186 (GRCm39) |
splice site |
probably benign |
|
|
R0606:Ift172
|
UTSW |
5 |
31,411,657 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0973:Ift172
|
UTSW |
5 |
31,415,262 (GRCm39) |
unclassified |
probably benign |
|
|
R0973:Ift172
|
UTSW |
5 |
31,422,699 (GRCm39) |
missense |
probably benign |
|
|
R1189:Ift172
|
UTSW |
5 |
31,443,174 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1205:Ift172
|
UTSW |
5 |
31,443,136 (GRCm39) |
missense |
probably benign |
|
|
R1289:Ift172
|
UTSW |
5 |
31,438,320 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1342:Ift172
|
UTSW |
5 |
31,419,210 (GRCm39) |
missense |
probably benign |
|
|
R1395:Ift172
|
UTSW |
5 |
31,442,582 (GRCm39) |
unclassified |
probably benign |
|
|
R1417:Ift172
|
UTSW |
5 |
31,413,993 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2020:Ift172
|
UTSW |
5 |
31,424,585 (GRCm39) |
nonsense |
probably null |
|
|
R2111:Ift172
|
UTSW |
5 |
31,443,423 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2175:Ift172
|
UTSW |
5 |
31,424,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2509:Ift172
|
UTSW |
5 |
31,420,312 (GRCm39) |
missense |
probably benign |
|
|
R2870:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2870:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2871:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2871:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2872:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2872:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3705:Ift172
|
UTSW |
5 |
31,418,781 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3793:Ift172
|
UTSW |
5 |
31,414,925 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R4385:Ift172
|
UTSW |
5 |
31,444,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4477:Ift172
|
UTSW |
5 |
31,422,781 (GRCm39) |
missense |
probably benign |
0.38 |
|
R4590:Ift172
|
UTSW |
5 |
31,411,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4663:Ift172
|
UTSW |
5 |
31,441,559 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4665:Ift172
|
UTSW |
5 |
31,442,598 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4977:Ift172
|
UTSW |
5 |
31,429,460 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5109:Ift172
|
UTSW |
5 |
31,423,330 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5182:Ift172
|
UTSW |
5 |
31,424,958 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5343:Ift172
|
UTSW |
5 |
31,421,156 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5465:Ift172
|
UTSW |
5 |
31,418,862 (GRCm39) |
splice site |
probably null |
|
|
R5622:Ift172
|
UTSW |
5 |
31,440,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5718:Ift172
|
UTSW |
5 |
31,412,621 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5793:Ift172
|
UTSW |
5 |
31,434,292 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5870:Ift172
|
UTSW |
5 |
31,434,284 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5919:Ift172
|
UTSW |
5 |
31,418,006 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5968:Ift172
|
UTSW |
5 |
31,418,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6112:Ift172
|
UTSW |
5 |
31,414,241 (GRCm39) |
missense |
probably benign |
|
|
R6339:Ift172
|
UTSW |
5 |
31,444,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6339:Ift172
|
UTSW |
5 |
31,413,927 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6355:Ift172
|
UTSW |
5 |
31,441,501 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6565:Ift172
|
UTSW |
5 |
31,433,227 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6668:Ift172
|
UTSW |
5 |
31,412,683 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6755:Ift172
|
UTSW |
5 |
31,418,342 (GRCm39) |
nonsense |
probably null |
|
|
R6818:Ift172
|
UTSW |
5 |
31,423,304 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6939:Ift172
|
UTSW |
5 |
31,414,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6980:Ift172
|
UTSW |
5 |
31,414,730 (GRCm39) |
missense |
probably benign |
|
|
R7047:Ift172
|
UTSW |
5 |
31,433,238 (GRCm39) |
nonsense |
probably null |
|
|
R7156:Ift172
|
UTSW |
5 |
31,429,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7180:Ift172
|
UTSW |
5 |
31,411,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7288:Ift172
|
UTSW |
5 |
31,442,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7351:Ift172
|
UTSW |
5 |
31,433,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7706:Ift172
|
UTSW |
5 |
31,423,723 (GRCm39) |
nonsense |
probably null |
|
|
R7890:Ift172
|
UTSW |
5 |
31,440,425 (GRCm39) |
nonsense |
probably null |
|
|
R7980:Ift172
|
UTSW |
5 |
31,417,988 (GRCm39) |
missense |
probably benign |
|
|
R8263:Ift172
|
UTSW |
5 |
31,422,681 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8559:Ift172
|
UTSW |
5 |
31,413,921 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8717:Ift172
|
UTSW |
5 |
31,412,985 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8774:Ift172
|
UTSW |
5 |
31,415,207 (GRCm39) |
missense |
probably benign |
0.45 |
|
R8774-TAIL:Ift172
|
UTSW |
5 |
31,415,207 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9037:Ift172
|
UTSW |
5 |
31,420,400 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9038:Ift172
|
UTSW |
5 |
31,441,399 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9133:Ift172
|
UTSW |
5 |
31,442,867 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9607:Ift172
|
UTSW |
5 |
31,410,913 (GRCm39) |
missense |
|
|
|
X0022:Ift172
|
UTSW |
5 |
31,442,664 (GRCm39) |
missense |
probably damaging |
0.97 |
|
Z1176:Ift172
|
UTSW |
5 |
31,434,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TACAGGTCCAAGGCAGCTACTACG -3'
(R):5'- AGCAATCGATGCTTTCATTGAGGGG -3'
Sequencing Primer
(F):5'- gctcagcctcttgaccc -3'
(R):5'- ATGCTTTCATTGAGGGGGAAGAG -3'
|
| Posted On |
2013-10-16 |
Incidental Mutation