Incidental Mutation 'R0827:Eps8l1'
| ID |
78310 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Eps8l1
|
| Ensembl Gene |
ENSMUSG00000006154 |
| Gene Name |
EPS8-like 1 |
| Synonyms |
DRC3, EPS8R1, 4632407K17Rik, 2310051G19Rik |
| MMRRC Submission |
039007-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0827 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
4463673-4483486 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 4480388 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 543
(V543A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133206
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000013886]
[ENSMUST00000086372]
[ENSMUST00000124248]
[ENSMUST00000163137]
[ENSMUST00000163893]
[ENSMUST00000171445]
[ENSMUST00000164987]
|
| AlphaFold |
Q8R5F8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000013886
|
| SMART Domains |
Protein: ENSMUSP00000013886
Gene: ENSMUSG00000019254
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
74 |
97 |
N/A |
INTRINSIC |
|
ANK
|
104 |
133 |
3.71e-4 |
SMART |
|
ANK
|
137 |
166 |
3.43e-8 |
SMART |
|
low complexity region
|
205 |
210 |
N/A |
INTRINSIC |
|
ANK
|
230 |
259 |
7.95e-4 |
SMART |
|
ANK
|
263 |
292 |
2.41e-3 |
SMART |
|
low complexity region
|
369 |
385 |
N/A |
INTRINSIC |
|
low complexity region
|
401 |
413 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
450 |
508 |
2.86e-5 |
PROSPERO |
|
internal_repeat_2
|
545 |
599 |
2.86e-5 |
PROSPERO |
|
low complexity region
|
631 |
649 |
N/A |
INTRINSIC |
|
Pfam:PRKG1_interact
|
682 |
782 |
9.7e-33 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000086372
AA Change: V482A
PolyPhen 2
Score 0.143 (Sensitivity: 0.92; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000083559
Gene: ENSMUSG00000006154
AA Change: V482A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PTB
|
35 |
165 |
2.1e-46 |
PFAM |
|
low complexity region
|
282 |
304 |
N/A |
INTRINSIC |
|
SH3
|
480 |
535 |
2.62e-11 |
SMART |
|
low complexity region
|
554 |
564 |
N/A |
INTRINSIC |
|
PDB:1WWU|A
|
632 |
698 |
1e-19 |
PDB |
|
low complexity region
|
701 |
715 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000124248
|
| SMART Domains |
Protein: ENSMUSP00000120029
Gene: ENSMUSG00000019254
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
25 |
54 |
3.71e-4 |
SMART |
|
ANK
|
58 |
87 |
3.43e-8 |
SMART |
|
low complexity region
|
126 |
131 |
N/A |
INTRINSIC |
|
ANK
|
151 |
180 |
7.95e-4 |
SMART |
|
ANK
|
184 |
213 |
2.41e-3 |
SMART |
|
low complexity region
|
290 |
306 |
N/A |
INTRINSIC |
|
low complexity region
|
322 |
334 |
N/A |
INTRINSIC |
|
PDB:2KJY|A
|
445 |
498 |
3e-11 |
PDB |
|
low complexity region
|
553 |
571 |
N/A |
INTRINSIC |
|
coiled coil region
|
604 |
704 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000127329
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000153101
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163137
|
| SMART Domains |
Protein: ENSMUSP00000131345
Gene: ENSMUSG00000006154
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PTB
|
35 |
100 |
1.9e-22 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163893
AA Change: V482A
PolyPhen 2
Score 0.143 (Sensitivity: 0.92; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000125840
Gene: ENSMUSG00000006154
AA Change: V482A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PTB
|
35 |
165 |
2.1e-46 |
PFAM |
|
low complexity region
|
282 |
304 |
N/A |
INTRINSIC |
|
SH3
|
480 |
535 |
2.62e-11 |
SMART |
|
low complexity region
|
554 |
564 |
N/A |
INTRINSIC |
|
PDB:1WWU|A
|
632 |
698 |
1e-19 |
PDB |
|
low complexity region
|
701 |
715 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000171445
AA Change: V543A
PolyPhen 2
Score 0.855 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000133206
Gene: ENSMUSG00000006154
AA Change: V543A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PTB
|
96 |
226 |
5.8e-46 |
PFAM |
|
low complexity region
|
343 |
365 |
N/A |
INTRINSIC |
|
SH3
|
541 |
596 |
2.62e-11 |
SMART |
|
low complexity region
|
615 |
625 |
N/A |
INTRINSIC |
|
PDB:1WWU|A
|
693 |
759 |
1e-19 |
PDB |
|
low complexity region
|
762 |
776 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000168924
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000167068
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000164987
|
| SMART Domains |
Protein: ENSMUSP00000130665
Gene: ENSMUSG00000006154
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
25 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.2775 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.1%
- 20x: 93.6%
|
| Validation Efficiency |
100% (88/88) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acan |
T |
C |
7: 78,749,419 (GRCm39) |
S1397P |
probably benign |
Het |
| Adamts15 |
T |
C |
9: 30,832,776 (GRCm39) |
Y253C |
probably damaging |
Het |
| Ankk1 |
A |
G |
9: 49,333,037 (GRCm39) |
I149T |
possibly damaging |
Het |
| Ankrd63 |
A |
G |
2: 118,533,034 (GRCm39) |
S296P |
possibly damaging |
Het |
| Arpc1b |
T |
G |
5: 145,062,566 (GRCm39) |
C227G |
probably benign |
Het |
| B4gat1 |
A |
G |
19: 5,089,725 (GRCm39) |
R241G |
possibly damaging |
Het |
| Ccar2 |
T |
C |
14: 70,377,287 (GRCm39) |
N751D |
probably benign |
Het |
| Cd55b |
T |
C |
1: 130,341,973 (GRCm39) |
I221M |
probably damaging |
Het |
| Cntn5 |
A |
G |
9: 9,666,943 (GRCm39) |
V1032A |
possibly damaging |
Het |
| Col11a1 |
G |
A |
3: 113,932,414 (GRCm39) |
R113H |
unknown |
Het |
| Colec10 |
G |
A |
15: 54,325,980 (GRCm39) |
C270Y |
probably damaging |
Het |
| Ctnnbl1 |
C |
T |
2: 157,641,337 (GRCm39) |
|
probably benign |
Het |
| Cyp2j12 |
T |
G |
4: 96,001,099 (GRCm39) |
|
probably benign |
Het |
| Dennd5a |
G |
A |
7: 109,498,938 (GRCm39) |
T999M |
probably damaging |
Het |
| Dusp13b |
C |
A |
14: 21,792,839 (GRCm39) |
V29L |
probably benign |
Het |
| Efr3a |
A |
C |
15: 65,725,400 (GRCm39) |
D83A |
possibly damaging |
Het |
| Elmod2 |
A |
G |
8: 84,043,424 (GRCm39) |
|
probably null |
Het |
| Eml3 |
C |
A |
19: 8,915,830 (GRCm39) |
T640K |
probably damaging |
Het |
| Ermn |
T |
C |
2: 57,938,263 (GRCm39) |
K117E |
probably damaging |
Het |
| F830045P16Rik |
A |
G |
2: 129,314,696 (GRCm39) |
S194P |
probably benign |
Het |
| Faim2 |
A |
G |
15: 99,422,617 (GRCm39) |
V60A |
probably benign |
Het |
| Fancd2 |
G |
A |
6: 113,563,210 (GRCm39) |
|
probably null |
Het |
| Fbxo43 |
A |
T |
15: 36,163,115 (GRCm39) |
S31T |
possibly damaging |
Het |
| Gab2 |
G |
A |
7: 96,949,539 (GRCm39) |
R411Q |
probably damaging |
Het |
| Gpm6a |
A |
T |
8: 55,511,918 (GRCm39) |
D264V |
probably damaging |
Het |
| H1f6 |
A |
G |
13: 23,880,204 (GRCm39) |
D119G |
probably benign |
Het |
| Hsp90aa1 |
T |
C |
12: 110,659,129 (GRCm39) |
E556G |
probably benign |
Het |
| Ifi203 |
A |
T |
1: 173,756,029 (GRCm39) |
|
probably benign |
Het |
| Iqca1 |
C |
A |
1: 90,070,453 (GRCm39) |
G133V |
probably null |
Het |
| Kcnc3 |
A |
G |
7: 44,244,630 (GRCm39) |
T307A |
probably damaging |
Het |
| Kin |
C |
A |
2: 10,095,187 (GRCm39) |
|
probably benign |
Het |
| Knl1 |
T |
C |
2: 118,919,382 (GRCm39) |
|
probably benign |
Het |
| Lrp4 |
G |
A |
2: 91,325,386 (GRCm39) |
V1404M |
probably damaging |
Het |
| Lrrc71 |
T |
A |
3: 87,649,952 (GRCm39) |
|
probably null |
Het |
| Med13l |
T |
C |
5: 118,864,312 (GRCm39) |
|
probably benign |
Het |
| Mfap5 |
A |
G |
6: 122,497,879 (GRCm39) |
D39G |
probably damaging |
Het |
| Mlxipl |
T |
C |
5: 135,161,592 (GRCm39) |
S504P |
probably benign |
Het |
| Myo3a |
T |
G |
2: 22,448,227 (GRCm39) |
Y1D |
probably damaging |
Het |
| Nek1 |
A |
G |
8: 61,558,682 (GRCm39) |
|
probably benign |
Het |
| Nfkbiz |
T |
C |
16: 55,636,730 (GRCm39) |
R524G |
probably damaging |
Het |
| Npbwr1 |
T |
C |
1: 5,987,008 (GRCm39) |
T169A |
possibly damaging |
Het |
| Nuggc |
T |
C |
14: 65,846,340 (GRCm39) |
Y84H |
probably damaging |
Het |
| Nxph3 |
G |
A |
11: 95,402,252 (GRCm39) |
S54L |
probably benign |
Het |
| Or13a21 |
A |
G |
7: 139,999,380 (GRCm39) |
F102S |
probably damaging |
Het |
| Or9e1 |
T |
C |
11: 58,732,597 (GRCm39) |
I219T |
probably damaging |
Het |
| Ostn |
A |
G |
16: 27,143,381 (GRCm39) |
N70D |
probably damaging |
Het |
| Pate7 |
A |
T |
9: 35,689,147 (GRCm39) |
L12Q |
probably damaging |
Het |
| Pcdhb2 |
G |
A |
18: 37,428,710 (GRCm39) |
V228I |
possibly damaging |
Het |
| Pnpla6 |
A |
T |
8: 3,567,618 (GRCm39) |
M109L |
possibly damaging |
Het |
| Ppil6 |
T |
A |
10: 41,370,500 (GRCm39) |
|
probably benign |
Het |
| Prss46 |
A |
G |
9: 110,680,500 (GRCm39) |
N215S |
probably benign |
Het |
| Ptprd |
A |
T |
4: 76,047,152 (GRCm39) |
D371E |
probably damaging |
Het |
| Ripor2 |
T |
A |
13: 24,878,169 (GRCm39) |
F315I |
probably damaging |
Het |
| Rmi2 |
G |
A |
16: 10,653,104 (GRCm39) |
G51S |
probably damaging |
Het |
| Scg3 |
A |
G |
9: 75,590,979 (GRCm39) |
I10T |
possibly damaging |
Het |
| Scn9a |
T |
A |
2: 66,366,468 (GRCm39) |
K761* |
probably null |
Het |
| Scyl2 |
A |
G |
10: 89,493,727 (GRCm39) |
L347P |
possibly damaging |
Het |
| Sh3d21 |
A |
G |
4: 126,046,064 (GRCm39) |
|
probably benign |
Het |
| Shc1 |
T |
A |
3: 89,334,090 (GRCm39) |
|
probably null |
Het |
| Slbp |
A |
G |
5: 33,801,166 (GRCm39) |
S182P |
probably damaging |
Het |
| Slc24a1 |
C |
T |
9: 64,835,472 (GRCm39) |
G885D |
probably benign |
Het |
| Slc24a3 |
T |
C |
2: 145,360,412 (GRCm39) |
|
probably benign |
Het |
| Sowahb |
T |
G |
5: 93,191,145 (GRCm39) |
N525H |
probably damaging |
Het |
| Sppl3 |
T |
A |
5: 115,220,392 (GRCm39) |
C101* |
probably null |
Het |
| Srsf5 |
A |
G |
12: 80,996,314 (GRCm39) |
K163E |
probably damaging |
Het |
| Sult2a4 |
A |
G |
7: 13,718,886 (GRCm39) |
I119T |
probably benign |
Het |
| Svep1 |
A |
G |
4: 58,053,113 (GRCm39) |
|
probably benign |
Het |
| Tas1r3 |
G |
A |
4: 155,945,326 (GRCm39) |
R632W |
probably benign |
Het |
| Tlr4 |
T |
A |
4: 66,752,117 (GRCm39) |
|
probably null |
Het |
| Tmf1 |
A |
C |
6: 97,135,011 (GRCm39) |
L1001* |
probably null |
Het |
| Tnnt2 |
A |
G |
1: 135,771,534 (GRCm39) |
|
probably benign |
Het |
| Trank1 |
G |
A |
9: 111,178,485 (GRCm39) |
|
probably benign |
Het |
| Trdn |
A |
T |
10: 33,275,154 (GRCm39) |
|
probably benign |
Het |
| Trmt6 |
A |
T |
2: 132,657,754 (GRCm39) |
V34E |
probably damaging |
Het |
| Trrap |
T |
C |
5: 144,751,640 (GRCm39) |
F1699L |
probably benign |
Het |
| Ttk |
A |
G |
9: 83,725,968 (GRCm39) |
R250G |
probably benign |
Het |
| Ttn |
T |
A |
2: 76,640,248 (GRCm39) |
I13787F |
probably damaging |
Het |
| Uggt1 |
T |
A |
1: 36,195,394 (GRCm39) |
|
probably null |
Het |
| Ugt2b35 |
T |
A |
5: 87,155,989 (GRCm39) |
|
probably benign |
Het |
| Ugt2b36 |
C |
A |
5: 87,214,234 (GRCm39) |
R470L |
possibly damaging |
Het |
| Unk |
A |
G |
11: 115,943,935 (GRCm39) |
D352G |
possibly damaging |
Het |
| Vmn2r77 |
G |
T |
7: 86,451,224 (GRCm39) |
C370F |
probably damaging |
Het |
| Vmn2r85 |
A |
G |
10: 130,265,387 (GRCm39) |
I32T |
possibly damaging |
Het |
| Zfp637 |
A |
G |
6: 117,822,405 (GRCm39) |
I178V |
possibly damaging |
Het |
| Zfp943 |
A |
G |
17: 22,211,071 (GRCm39) |
|
probably null |
Het |
| Zyg11a |
A |
G |
4: 108,067,239 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Eps8l1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01292:Eps8l1
|
APN |
7 |
4,481,919 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL01455:Eps8l1
|
APN |
7 |
4,481,922 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL01872:Eps8l1
|
APN |
7 |
4,475,295 (GRCm39) |
splice site |
probably benign |
|
|
IGL02343:Eps8l1
|
APN |
7 |
4,475,123 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02585:Eps8l1
|
APN |
7 |
4,472,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02596:Eps8l1
|
APN |
7 |
4,473,871 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02673:Eps8l1
|
APN |
7 |
4,481,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03117:Eps8l1
|
APN |
7 |
4,473,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Anamnestic
|
UTSW |
7 |
4,473,873 (GRCm39) |
missense |
probably damaging |
0.98 |
|
souvenir
|
UTSW |
7 |
4,480,895 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
PIT4142001:Eps8l1
|
UTSW |
7 |
4,474,414 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4151001:Eps8l1
|
UTSW |
7 |
4,474,414 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4480001:Eps8l1
|
UTSW |
7 |
4,474,414 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0015:Eps8l1
|
UTSW |
7 |
4,480,556 (GRCm39) |
splice site |
probably benign |
|
|
R0599:Eps8l1
|
UTSW |
7 |
4,480,956 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0686:Eps8l1
|
UTSW |
7 |
4,480,449 (GRCm39) |
missense |
probably benign |
0.36 |
|
R1015:Eps8l1
|
UTSW |
7 |
4,472,932 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1447:Eps8l1
|
UTSW |
7 |
4,477,055 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1490:Eps8l1
|
UTSW |
7 |
4,473,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1527:Eps8l1
|
UTSW |
7 |
4,474,393 (GRCm39) |
missense |
probably benign |
|
|
R1553:Eps8l1
|
UTSW |
7 |
4,480,448 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1763:Eps8l1
|
UTSW |
7 |
4,474,822 (GRCm39) |
missense |
probably benign |
0.43 |
|
R1863:Eps8l1
|
UTSW |
7 |
4,468,359 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R2357:Eps8l1
|
UTSW |
7 |
4,473,354 (GRCm39) |
missense |
probably benign |
0.06 |
|
R3153:Eps8l1
|
UTSW |
7 |
4,474,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4082:Eps8l1
|
UTSW |
7 |
4,473,797 (GRCm39) |
splice site |
probably null |
|
|
R4539:Eps8l1
|
UTSW |
7 |
4,481,623 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4684:Eps8l1
|
UTSW |
7 |
4,476,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4930:Eps8l1
|
UTSW |
7 |
4,463,915 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4931:Eps8l1
|
UTSW |
7 |
4,474,240 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5245:Eps8l1
|
UTSW |
7 |
4,473,873 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5247:Eps8l1
|
UTSW |
7 |
4,473,401 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5305:Eps8l1
|
UTSW |
7 |
4,480,895 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R5420:Eps8l1
|
UTSW |
7 |
4,473,160 (GRCm39) |
splice site |
probably null |
|
|
R5620:Eps8l1
|
UTSW |
7 |
4,463,945 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5705:Eps8l1
|
UTSW |
7 |
4,473,034 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6063:Eps8l1
|
UTSW |
7 |
4,474,296 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6909:Eps8l1
|
UTSW |
7 |
4,472,899 (GRCm39) |
nonsense |
probably null |
|
|
R7096:Eps8l1
|
UTSW |
7 |
4,477,190 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7136:Eps8l1
|
UTSW |
7 |
4,480,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7144:Eps8l1
|
UTSW |
7 |
4,475,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7381:Eps8l1
|
UTSW |
7 |
4,473,437 (GRCm39) |
splice site |
probably null |
|
|
R7539:Eps8l1
|
UTSW |
7 |
4,473,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7784:Eps8l1
|
UTSW |
7 |
4,475,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7833:Eps8l1
|
UTSW |
7 |
4,471,866 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R8190:Eps8l1
|
UTSW |
7 |
4,474,297 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8311:Eps8l1
|
UTSW |
7 |
4,474,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8549:Eps8l1
|
UTSW |
7 |
4,473,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8960:Eps8l1
|
UTSW |
7 |
4,481,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8974:Eps8l1
|
UTSW |
7 |
4,474,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9003:Eps8l1
|
UTSW |
7 |
4,464,016 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9023:Eps8l1
|
UTSW |
7 |
4,477,042 (GRCm39) |
nonsense |
probably null |
|
|
R9131:Eps8l1
|
UTSW |
7 |
4,480,573 (GRCm39) |
missense |
|
|
|
R9517:Eps8l1
|
UTSW |
7 |
4,480,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9653:Eps8l1
|
UTSW |
7 |
4,481,886 (GRCm39) |
missense |
unknown |
|
|
X0060:Eps8l1
|
UTSW |
7 |
4,473,850 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCTCCTGCTTGGCTCTAACTAATG -3'
(R):5'- ACATAGCCCTCTTGTCCCTGATGG -3'
Sequencing Primer
(F):5'- TAATCCAGACCATTGAGGCC -3'
(R):5'- GATGGTCCCGAACCTTCCAC -3'
|
| Posted On |
2013-10-16 |
Incidental Mutation