Incidental Mutation 'IGL01382:Vmn1r7'
ID78886
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r7
Ensembl Gene ENSMUSG00000093696
Gene Namevomeronasal 1 receptor 7
SynonymsGm5568, V1rc31
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.129) question?
Stock #IGL01382
Quality Score
Status
Chromosome6
Chromosomal Location57024106-57025324 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 57024723 bp
ZygosityHeterozygous
Amino Acid Change Aspartic acid to Valine at position 184 (D184V)
Ref Sequence ENSEMBL: ENSMUSP00000135571 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000176252]
Predicted Effect probably damaging
Transcript: ENSMUST00000176252
AA Change: D184V

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
SMART Domains Protein: ENSMUSP00000135571
Gene: ENSMUSG00000093696
AA Change: D184V

DomainStartEndE-ValueType
Pfam:V1R 28 293 1.1e-59 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 39 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ap5z1 G T 5: 142,472,251 R393L probably benign Het
Arhgap21 G T 2: 20,855,700 P1128T probably damaging Het
Atp12a T G 14: 56,379,955 C567W probably damaging Het
Bcat2 C A 7: 45,588,260 R312S probably damaging Het
Cacna1g T A 11: 94,465,858 T151S probably damaging Het
Chid1 G A 7: 141,530,253 T53M probably damaging Het
Dis3l2 A G 1: 86,857,203 D272G probably benign Het
Ephx4 A G 5: 107,429,719 E303G probably damaging Het
Fam189b T C 3: 89,188,426 S596P probably damaging Het
Fsd1 C T 17: 55,996,733 S491F probably damaging Het
Gm9843 A T 16: 76,403,572 noncoding transcript Het
Gnb1l T C 16: 18,544,200 F11S probably damaging Het
Ipmk C T 10: 71,376,766 T186M probably damaging Het
Jph1 T C 1: 17,016,156 T381A probably damaging Het
Kbtbd8 T A 6: 95,122,230 I163K probably damaging Het
Kif18a T A 2: 109,296,766 Y348* probably null Het
Lrrc37a T A 11: 103,498,755 D1948V probably damaging Het
Mc4r A G 18: 66,859,793 I83T probably damaging Het
Myh8 A T 11: 67,301,973 E1530V probably damaging Het
Naip6 C T 13: 100,299,856 E720K possibly damaging Het
Ncor2 T A 5: 125,055,773 Q50L probably damaging Het
Olfr1411 A G 1: 92,597,200 Y227C possibly damaging Het
Olfr495 G A 7: 108,395,245 V42M probably benign Het
Plxnd1 A T 6: 115,960,527 M1575K probably damaging Het
Ptprg T G 14: 12,237,797 M643R probably benign Het
Reck T A 4: 43,940,662 C824S probably damaging Het
Rpgrip1 C T 14: 52,145,477 T689I possibly damaging Het
Ruvbl2 A T 7: 45,422,737 S358T probably benign Het
Sec14l3 G T 11: 4,068,104 C128F probably damaging Het
Serpinf2 C T 11: 75,438,037 probably benign Het
Sez6l C T 5: 112,425,621 V842I probably benign Het
Tm6sf2 A G 8: 70,078,368 Y257C probably damaging Het
Tmpo T C 10: 91,166,050 D99G probably damaging Het
Tulp3 A C 6: 128,325,070 N329K probably damaging Het
Vmn2r24 A G 6: 123,786,979 T272A possibly damaging Het
Vmn2r93 T A 17: 18,313,316 L494* probably null Het
Wdr18 T C 10: 79,965,272 L173P probably damaging Het
Zfp663 T A 2: 165,359,015 Y33F probably damaging Het
Zmiz2 T A 11: 6,403,781 probably null Het
Other mutations in Vmn1r7
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01528:Vmn1r7 APN 6 57024547 missense probably benign
IGL02024:Vmn1r7 APN 6 57024889 missense probably benign 0.01
IGL02234:Vmn1r7 APN 6 57024552 missense probably damaging 0.98
IGL02610:Vmn1r7 APN 6 57025052 missense probably benign 0.01
IGL02691:Vmn1r7 APN 6 57024388 missense probably benign 0.05
R0529:Vmn1r7 UTSW 6 57024465 missense possibly damaging 0.78
R0548:Vmn1r7 UTSW 6 57025081 missense probably damaging 0.96
R1254:Vmn1r7 UTSW 6 57024787 missense probably damaging 1.00
R1279:Vmn1r7 UTSW 6 57024949 missense possibly damaging 0.63
R1582:Vmn1r7 UTSW 6 57025158 missense probably damaging 1.00
R1973:Vmn1r7 UTSW 6 57025026 missense probably benign 0.00
R1991:Vmn1r7 UTSW 6 57024868 missense probably benign 0.37
R2160:Vmn1r7 UTSW 6 57024894 missense probably damaging 0.97
R3546:Vmn1r7 UTSW 6 57024849 missense possibly damaging 0.80
R3547:Vmn1r7 UTSW 6 57024849 missense possibly damaging 0.80
R5901:Vmn1r7 UTSW 6 57024606 missense probably damaging 1.00
R6294:Vmn1r7 UTSW 6 57024419 missense probably benign 0.00
R7063:Vmn1r7 UTSW 6 57024433 missense possibly damaging 0.63
R7192:Vmn1r7 UTSW 6 57024467 missense probably benign 0.00
R7647:Vmn1r7 UTSW 6 57025270 missense probably benign 0.01
R7781:Vmn1r7 UTSW 6 57024568 missense probably benign 0.03
Posted On2013-11-05