Incidental Mutation 'IGL01383:Psg26'
ID78932
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Psg26
Ensembl Gene ENSMUSG00000070799
Gene Namepregnancy-specific glycoprotein 26
SynonymsEG574429, cea14
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.054) question?
Stock #IGL01383
Quality Score
Status
Chromosome7
Chromosomal Location18474582-18484177 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 18480254 bp
ZygosityHeterozygous
Amino Acid Change Valine to Alanine at position 161 (V161A)
Ref Sequence ENSEMBL: ENSMUSP00000092392 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000094798]
Predicted Effect possibly damaging
Transcript: ENSMUST00000094798
AA Change: V161A

PolyPhen 2 Score 0.900 (Sensitivity: 0.82; Specificity: 0.94)
SMART Domains Protein: ENSMUSP00000092392
Gene: ENSMUSG00000070799
AA Change: V161A

DomainStartEndE-ValueType
IG 40 141 4.93e-3 SMART
IG 160 261 2.39e-1 SMART
IG 280 379 6.07e-3 SMART
IGc2 397 461 5.48e-10 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 41 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930555G01Rik C A 14: 5,051,570 probably null Het
4931409K22Rik A T 5: 24,548,294 N453K probably benign Het
Abca9 A C 11: 110,113,293 probably benign Het
Aox2 T A 1: 58,294,305 M227K probably benign Het
Asb5 T A 8: 54,550,509 L22H probably damaging Het
Atrx T C X: 105,802,075 D2309G probably damaging Het
Cand1 T A 10: 119,208,167 T1074S probably damaging Het
Ccdc114 T C 7: 45,939,700 S179P probably damaging Het
Cep97 T C 16: 55,911,607 E534G probably damaging Het
Cftr C A 6: 18,226,041 N329K probably benign Het
Clec7a T C 6: 129,472,640 T16A probably damaging Het
Col1a1 G A 11: 94,945,525 R674H probably damaging Het
Csf2rb2 T C 15: 78,297,043 S50G possibly damaging Het
Eepd1 A G 9: 25,482,482 D14G probably damaging Het
Fsd1 C T 17: 55,996,733 S491F probably damaging Het
Gm13103 T G 4: 143,846,532 probably benign Het
Grin1 C A 2: 25,296,967 R694L possibly damaging Het
Gtf3c1 A G 7: 125,699,500 I151T probably damaging Het
Havcr2 T C 11: 46,469,548 S152P probably damaging Het
Hvcn1 T C 5: 122,237,703 V15A probably damaging Het
Map3k10 C T 7: 27,657,999 V785M probably benign Het
Mis18bp1 T C 12: 65,148,989 N667S probably benign Het
Mup3 A C 4: 62,085,959 Y106D probably damaging Het
Mypn G T 10: 63,135,797 N821K probably damaging Het
Olfr1386 T A 11: 49,471,053 W301R probably benign Het
Olfr152 A G 2: 87,782,873 D111G possibly damaging Het
Olfr209 A T 16: 59,361,953 N88K probably benign Het
Olfr547 A G 7: 102,534,933 Y62C probably benign Het
Pcdhb10 A T 18: 37,413,275 H468L probably benign Het
Prp2 C A 6: 132,599,878 P43T unknown Het
Rab17 T G 1: 90,960,093 D115A probably damaging Het
Rrp1b T C 17: 32,058,578 F611L probably damaging Het
Skor1 T A 9: 63,146,556 T44S probably benign Het
Spaca5 T C X: 21,068,486 probably benign Het
Tatdn3 G A 1: 191,055,381 probably benign Het
Tbk1 T C 10: 121,576,279 D118G probably damaging Het
Tnfsf13b T C 8: 10,031,528 F230S probably damaging Het
Tnrc6c T C 11: 117,714,257 S73P probably benign Het
Vmn2r109 A G 17: 20,541,121 V658A possibly damaging Het
Vmn2r116 C T 17: 23,401,601 L770F probably damaging Het
Wwp2 T A 8: 107,533,291 probably null Het
Other mutations in Psg26
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01010:Psg26 APN 7 18478330 missense possibly damaging 0.83
IGL01453:Psg26 APN 7 18480074 missense possibly damaging 0.91
IGL01603:Psg26 APN 7 18475103 missense probably damaging 0.98
IGL02201:Psg26 APN 7 18480146 missense probably benign 0.04
IGL02468:Psg26 APN 7 18478462 missense probably damaging 0.96
IGL02648:Psg26 APN 7 18482766 missense probably benign 0.05
IGL02812:Psg26 APN 7 18475155 missense probably benign 0.00
R0226:Psg26 UTSW 7 18483958 missense possibly damaging 0.81
R0352:Psg26 UTSW 7 18475256 missense probably benign 0.00
R0369:Psg26 UTSW 7 18482556 nonsense probably null
R0718:Psg26 UTSW 7 18475235 missense probably benign 0.23
R0718:Psg26 UTSW 7 18478287 missense probably benign 0.18
R1710:Psg26 UTSW 7 18480041 missense probably damaging 0.99
R1899:Psg26 UTSW 7 18478425 missense probably benign 0.01
R1958:Psg26 UTSW 7 18478339 missense probably benign 0.04
R2102:Psg26 UTSW 7 18475142 missense probably damaging 1.00
R3766:Psg26 UTSW 7 18475071 missense probably benign
R4544:Psg26 UTSW 7 18478539 missense probably damaging 1.00
R4977:Psg26 UTSW 7 18475310 missense probably benign 0.11
R5000:Psg26 UTSW 7 18480132 missense possibly damaging 0.95
R5376:Psg26 UTSW 7 18480105 missense probably benign
R5416:Psg26 UTSW 7 18482600 missense probably benign
R5435:Psg26 UTSW 7 18478473 missense possibly damaging 0.60
R6000:Psg26 UTSW 7 18482692 nonsense probably null
R6285:Psg26 UTSW 7 18482828 missense probably benign
R7062:Psg26 UTSW 7 18482596 missense probably damaging 1.00
R7083:Psg26 UTSW 7 18480009 nonsense probably null
R7513:Psg26 UTSW 7 18475300 missense probably benign 0.03
R7817:Psg26 UTSW 7 18482647 missense not run
R7857:Psg26 UTSW 7 18478290 missense possibly damaging 0.71
R7905:Psg26 UTSW 7 18475317 missense probably benign 0.00
R7940:Psg26 UTSW 7 18478290 missense possibly damaging 0.71
R7988:Psg26 UTSW 7 18475317 missense probably benign 0.00
R8047:Psg26 UTSW 7 18478549 missense possibly damaging 0.50
Z1177:Psg26 UTSW 7 18480291 missense probably benign 0.02
Posted On2013-11-05