Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01391:Znhit3'

79238

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Znhit3

Ensembl Gene

ENSMUSG00000020526

Gene Name

zinc finger, HIT type 3

Synonyms

Trip3

Accession Numbers

Essential gene?

Probably essential (E-score: 0.791) question?

Stock #

IGL01391

Quality Score

Status

Chromosome

Chromosomal Location

84801776-84807192 bp(-) (GRCm39)

Type of Mutation

utr 3 prime

DNA Base Change (assembly)

A to T at 84802283 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000099484 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000093969] [ENSMUST00000103195]

AlphaFold

Q9CQK1

Predicted Effect

probably benign
Transcript: ENSMUST00000093969

SMART Domains

Protein: ENSMUSP00000091502
Gene: ENSMUSG00000020527

Domain	Start	End	E-Value	Type
MYSc	29	759	4.07e-219	SMART
IQ	760	782	1.74e1	SMART
IQ	783	804	1.97e0	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000103195

SMART Domains

Protein: ENSMUSP00000099484
Gene: ENSMUSG00000020526

Domain	Start	End	E-Value	Type
Pfam:zf-HIT	7	36	9.3e-13	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000124152

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000127838

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000136656

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000141173

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000141705

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000144552

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000156046

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 47 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Ap3m2	T	A	8: 23,289,663 (GRCm39)	I147F	probably benign	Het
Areg	T	A	5: 91,288,954 (GRCm39)	S87T	probably damaging	Het
Arid1b	T	A	17: 5,369,133 (GRCm39)		probably benign	Het
Arl6ip6	A	G	2: 53,082,156 (GRCm39)	R8G	probably benign	Het
Brms1	A	G	19: 5,096,723 (GRCm39)	E135G	possibly damaging	Het
Ccser1	A	G	6: 61,615,505 (GRCm39)		probably benign	Het
Dock3	A	T	9: 106,784,433 (GRCm39)	M258K	possibly damaging	Het
Epb41l4a	T	G	18: 33,934,678 (GRCm39)	D562A	possibly damaging	Het
Etaa1	G	A	11: 17,896,005 (GRCm39)	T704I	probably damaging	Het
Fer1l4	T	A	2: 155,878,376 (GRCm39)	H972L	probably damaging	Het
Foxn1	A	G	11: 78,252,320 (GRCm39)	M356T	probably damaging	Het
Gfral	C	A	9: 76,072,107 (GRCm39)	G388*	probably null	Het
Gm12258	A	G	11: 58,739,520 (GRCm39)	T3A	probably benign	Het
Hoxa5	T	C	6: 52,181,311 (GRCm39)	N7S	probably damaging	Het
Itgb4	T	C	11: 115,881,746 (GRCm39)	L765P	probably damaging	Het
Jchain	C	T	5: 88,669,383 (GRCm39)	C90Y	probably damaging	Het
Klhl40	A	G	9: 121,607,983 (GRCm39)	Y381C	probably damaging	Het
Lhx6	A	T	2: 35,993,477 (GRCm39)	C74S	probably benign	Het
Magel2	A	G	7: 62,030,632 (GRCm39)	S1179G	unknown	Het
Mapre3	T	C	5: 31,022,241 (GRCm39)	I236T	probably damaging	Het
Mcf2l	A	T	8: 13,064,010 (GRCm39)		probably null	Het
Med13	A	T	11: 86,219,323 (GRCm39)	H374Q	probably benign	Het
Meioc	A	G	11: 102,565,113 (GRCm39)	Y187C	probably benign	Het
Myh1	G	A	11: 67,108,689 (GRCm39)	M1368I	probably benign	Het
Or14a258	A	T	7: 86,035,208 (GRCm39)	I220N	possibly damaging	Het
Or8b54	A	G	9: 38,686,826 (GRCm39)	I92V	probably damaging	Het
Phrf1	T	C	7: 140,842,394 (GRCm39)	Y1501H	probably damaging	Het
Pigb	T	C	9: 72,929,573 (GRCm39)	T337A	probably damaging	Het
Pls1	T	C	9: 95,655,751 (GRCm39)	K334E	probably benign	Het
Pramel51	C	T	12: 88,145,225 (GRCm39)	V34I	possibly damaging	Het
Rab3b	T	C	4: 108,797,999 (GRCm39)	C226R	probably damaging	Het
Ryr2	A	T	13: 11,571,571 (GRCm39)	I4889N	possibly damaging	Het
Serpinb1a	G	A	13: 33,029,398 (GRCm39)	S210L	probably benign	Het
Slc52a3	A	G	2: 151,849,522 (GRCm39)	I390V	probably benign	Het
Slc6a7	C	A	18: 61,136,382 (GRCm39)	A340S	probably damaging	Het
Tcaf3	T	C	6: 42,570,615 (GRCm39)	Y379C	probably damaging	Het
Tex261	A	G	6: 83,748,222 (GRCm39)	V180A	probably benign	Het
Tnnt1	C	T	7: 4,517,211 (GRCm39)		probably null	Het
Ttn	T	C	2: 76,798,847 (GRCm39)	T476A	possibly damaging	Het
Vcan	A	G	13: 89,852,288 (GRCm39)	S891P	probably benign	Het
Vmn2r16	T	A	5: 109,511,627 (GRCm39)	D611E	possibly damaging	Het
Vmn2r68	T	C	7: 84,886,819 (GRCm39)	T32A	probably benign	Het
Vwde	T	G	6: 13,190,526 (GRCm39)	S522R	probably benign	Het
Wdr3	G	A	3: 100,054,105 (GRCm39)		probably benign	Het
Wfs1	G	T	5: 37,128,907 (GRCm39)	Q288K	probably benign	Het
Zfp142	A	G	1: 74,618,699 (GRCm39)	V120A	probably damaging	Het
Zfp672	A	G	11: 58,208,192 (GRCm39)	F43S	probably damaging	Het

Other mutations in Znhit3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01766:Znhit3	APN	11	84,806,959 (GRCm39)	splice site	probably benign
R4133:Znhit3	UTSW	11	84,807,139 (GRCm39)	missense	probably benign	0.03
R4625:Znhit3	UTSW	11	84,802,316 (GRCm39)	missense	probably damaging	0.99
R4700:Znhit3	UTSW	11	84,807,155 (GRCm39)	missense	probably benign	0.20
R5792:Znhit3	UTSW	11	84,806,910 (GRCm39)	splice site	probably null
Z1177:Znhit3	UTSW	11	84,804,076 (GRCm39)	missense	probably damaging	1.00

Posted On

2013-11-05