Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL01392:Gm7168'

79242

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm7168

Ensembl Gene

ENSMUSG00000067941

Gene Name

predicted gene 7168

Synonyms

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.096) question?

Stock #

IGL01392

Quality Score

Status

Chromosome

Chromosomal Location

13948373-13950678 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 13948907 bp

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Asparagine at position 179 (D179N)

Ref Sequence

ENSEMBL: ENSMUSP00000094997 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000088809]

Predicted Effect

probably benign
Transcript: ENSMUST00000088809
AA Change: D179N

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000094997
Gene: ENSMUSG00000067941
AA Change: D179N

Domain	Start	End	E-Value	Type
low complexity region	6	20	N/A	INTRINSIC
S_TKc	28	276	5.25e-91	SMART
UBA	296	333	4.39e-2	SMART
low complexity region	436	451	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 32 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acvr1	A	G	2: 58,500,546	V2A	probably benign	Het
Adgrf5	A	T	17: 43,450,012	Q866L	probably benign	Het
Ankrd13a	A	G	5: 114,797,853	E295G	probably benign	Het
Arid1a	T	C	4: 133,681,037	D2053G	unknown	Het
Calr4	A	G	4: 109,253,874	E272G	probably benign	Het
Cmya5	T	C	13: 93,089,206	S3125G	probably damaging	Het
Dnah7b	T	C	1: 46,126,788	Y538H	probably damaging	Het
Eri3	T	C	4: 117,589,159		probably null	Het
Fmo6	T	A	1: 162,930,011	R63*	probably null	Het
Gm8979	T	C	7: 106,083,755	I98V	probably benign	Het
Got1l1	T	C	8: 27,197,991	T337A	probably damaging	Het
Igf2r	A	G	17: 12,704,349	M1191T	probably benign	Het
Ighv1-54	A	G	12: 115,193,937	L30P	probably damaging	Het
Igkv8-30	A	G	6: 70,117,347	S27P	probably benign	Het
Kcnab2	A	T	4: 152,393,797	V335E	possibly damaging	Het
Klf12	A	T	14: 100,149,757	I3N	probably damaging	Het
Megf8	T	C	7: 25,363,749	V2510A	probably benign	Het
Mme	A	G	3: 63,362,046	D592G	probably damaging	Het
Myh1	A	G	11: 67,221,301	N1727S	probably benign	Het
Ncor1	A	G	11: 62,340,594	S796P	probably damaging	Het
Nlrp14	A	G	7: 107,197,913		probably benign	Het
Olfr1443	T	A	19: 12,680,803	Y232N	probably benign	Het
Olfr508	C	T	7: 108,630,678	R229C	probably benign	Het
Olfr564	T	A	7: 102,803,854	Y125*	probably null	Het
Plekhm2	A	G	4: 141,642,426	V86A	probably damaging	Het
Popdc2	G	T	16: 38,374,131	V305L	probably benign	Het
Prpmp5	T	C	6: 132,312,420	N147S	unknown	Het
Rttn	C	T	18: 88,995,613	H469Y	probably benign	Het
Slc2a12	T	C	10: 22,664,684	V146A	probably damaging	Het
Sptlc3	A	G	2: 139,546,421	E111G	possibly damaging	Het
Zfp108	T	C	7: 24,258,447		probably benign	Het
Zfp719	T	A	7: 43,591,130	F714Y	probably damaging	Het

Other mutations in Gm7168

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01298:Gm7168	APN	17	13949858	missense	probably benign	0.00
IGL01577:Gm7168	APN	17	13949387	missense	probably damaging	0.99
IGL01691:Gm7168	APN	17	13948878	missense	probably damaging	0.96
R0064:Gm7168	UTSW	17	13949859	missense	probably benign	0.21
R0611:Gm7168	UTSW	17	13949535	missense	probably benign
R0737:Gm7168	UTSW	17	13948983	missense	probably damaging	1.00
R1789:Gm7168	UTSW	17	13949584	missense	probably benign	0.03
R2864:Gm7168	UTSW	17	13949855	missense	probably benign	0.42
R2865:Gm7168	UTSW	17	13949855	missense	probably benign	0.42
R4179:Gm7168	UTSW	17	13949003	missense	probably benign	0.00
R4652:Gm7168	UTSW	17	13949807	missense	possibly damaging	0.88
R5174:Gm7168	UTSW	17	13948455	missense	probably damaging	1.00
R5722:Gm7168	UTSW	17	13949562	missense	probably benign
R6180:Gm7168	UTSW	17	13948596	missense	probably damaging	0.98
R7195:Gm7168	UTSW	17	13949360	missense	probably benign	0.01
R7366:Gm7168	UTSW	17	13949885	missense	probably damaging	1.00
R7490:Gm7168	UTSW	17	13949013	missense	probably benign	0.01
R7748:Gm7168	UTSW	17	13948652	missense	probably benign	0.03
X0020:Gm7168	UTSW	17	13949736	missense	probably benign	0.04

Posted On

2013-11-05