Incidental Mutation 'IGL01392:Gm7168'
ID79242
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm7168
Ensembl Gene ENSMUSG00000067941
Gene Namepredicted gene 7168
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.096) question?
Stock #IGL01392
Quality Score
Status
Chromosome17
Chromosomal Location13948373-13950678 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to A at 13948907 bp
ZygosityHeterozygous
Amino Acid Change Aspartic acid to Asparagine at position 179 (D179N)
Ref Sequence ENSEMBL: ENSMUSP00000094997 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000088809]
Predicted Effect probably benign
Transcript: ENSMUST00000088809
AA Change: D179N

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000094997
Gene: ENSMUSG00000067941
AA Change: D179N

DomainStartEndE-ValueType
low complexity region 6 20 N/A INTRINSIC
S_TKc 28 276 5.25e-91 SMART
UBA 296 333 4.39e-2 SMART
low complexity region 436 451 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 32 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acvr1 A G 2: 58,500,546 V2A probably benign Het
Adgrf5 A T 17: 43,450,012 Q866L probably benign Het
Ankrd13a A G 5: 114,797,853 E295G probably benign Het
Arid1a T C 4: 133,681,037 D2053G unknown Het
Calr4 A G 4: 109,253,874 E272G probably benign Het
Cmya5 T C 13: 93,089,206 S3125G probably damaging Het
Dnah7b T C 1: 46,126,788 Y538H probably damaging Het
Eri3 T C 4: 117,589,159 probably null Het
Fmo6 T A 1: 162,930,011 R63* probably null Het
Gm8979 T C 7: 106,083,755 I98V probably benign Het
Got1l1 T C 8: 27,197,991 T337A probably damaging Het
Igf2r A G 17: 12,704,349 M1191T probably benign Het
Ighv1-54 A G 12: 115,193,937 L30P probably damaging Het
Igkv8-30 A G 6: 70,117,347 S27P probably benign Het
Kcnab2 A T 4: 152,393,797 V335E possibly damaging Het
Klf12 A T 14: 100,149,757 I3N probably damaging Het
Megf8 T C 7: 25,363,749 V2510A probably benign Het
Mme A G 3: 63,362,046 D592G probably damaging Het
Myh1 A G 11: 67,221,301 N1727S probably benign Het
Ncor1 A G 11: 62,340,594 S796P probably damaging Het
Nlrp14 A G 7: 107,197,913 probably benign Het
Olfr1443 T A 19: 12,680,803 Y232N probably benign Het
Olfr508 C T 7: 108,630,678 R229C probably benign Het
Olfr564 T A 7: 102,803,854 Y125* probably null Het
Plekhm2 A G 4: 141,642,426 V86A probably damaging Het
Popdc2 G T 16: 38,374,131 V305L probably benign Het
Prpmp5 T C 6: 132,312,420 N147S unknown Het
Rttn C T 18: 88,995,613 H469Y probably benign Het
Slc2a12 T C 10: 22,664,684 V146A probably damaging Het
Sptlc3 A G 2: 139,546,421 E111G possibly damaging Het
Zfp108 T C 7: 24,258,447 probably benign Het
Zfp719 T A 7: 43,591,130 F714Y probably damaging Het
Other mutations in Gm7168
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01298:Gm7168 APN 17 13949858 missense probably benign 0.00
IGL01577:Gm7168 APN 17 13949387 missense probably damaging 0.99
IGL01691:Gm7168 APN 17 13948878 missense probably damaging 0.96
R0064:Gm7168 UTSW 17 13949859 missense probably benign 0.21
R0611:Gm7168 UTSW 17 13949535 missense probably benign
R0737:Gm7168 UTSW 17 13948983 missense probably damaging 1.00
R1789:Gm7168 UTSW 17 13949584 missense probably benign 0.03
R2864:Gm7168 UTSW 17 13949855 missense probably benign 0.42
R2865:Gm7168 UTSW 17 13949855 missense probably benign 0.42
R4179:Gm7168 UTSW 17 13949003 missense probably benign 0.00
R4652:Gm7168 UTSW 17 13949807 missense possibly damaging 0.88
R5174:Gm7168 UTSW 17 13948455 missense probably damaging 1.00
R5722:Gm7168 UTSW 17 13949562 missense probably benign
R6180:Gm7168 UTSW 17 13948596 missense probably damaging 0.98
R7195:Gm7168 UTSW 17 13949360 missense probably benign 0.01
R7366:Gm7168 UTSW 17 13949885 missense probably damaging 1.00
R7490:Gm7168 UTSW 17 13949013 missense probably benign 0.01
R7748:Gm7168 UTSW 17 13948652 missense probably benign 0.03
X0020:Gm7168 UTSW 17 13949736 missense probably benign 0.04
Posted On2013-11-05